Piroxicam medicinal preparation and preparing method thereof

Abstract

The invention relates to a pharmaceutical preparation of piroxicam and process for preparation, wherein the pharmaceutical preparation comprises 0.5-10 weight parts of piroxicam as active composition, 5-95 weight parts of medicinal adjuvant, and 5-90 weight parts of casting agent. The preparation has the advantages of easiness in use, higher safety and reliability, and better analgesic and analgesic effects.

Description

technical field [0001] The invention relates to the field of pharmaceutical preparations, in particular to a pharmaceutical preparation of piroxicam and a preparation method thereof. Background technique [0002] Piroxicam is an antipyretic and analgesic non-steroidal anti-inflammatory drug. At present, there are six dosage forms of piroxicam preparations on the market including ointment, tablet, capsule, injection, gel and liniment. The inconvenient use of injections is self-evident; capsules and tablets must be taken orally, digested and absorbed by the digestive tract, and detoxified by the liver after a series of functional effects and then enter the blood circulation to exert their antipyretic and analgesic effects. The dosage is 10mg~20mg once for an adult, and it has the common disadvantages of oral preparations, such as dose limitation in severe cases, slow action, stimulation and damage to internal organs, contraindications to internal organ ...

AI Technical Summary

Problems solved by technology

The inconvenient use of injections is self-evident; capsules and tablets must be taken orally, digested and absorbed by the digestive tract, and detoxified by the liver after a series of functional effects and then enter the blood circulation to exert their antipyretic and analgesic effects. The dosage is 10mg~20mg once for an adult, and it has the common disadvantages of oral preparations, such as dose limitation in severe cases, slow action, stimulation and damage to internal organs, contraindications to internal organ functions, etc., and it will be accompanied by some adverse reactions, such as A small number of patients may experience nausea, vomiting, stomach burning sensation or mild indigestion, gastrointestinal ulcers and bleeding, perforation, etc.; ointment, gel and liniment are more convenient, and there are no contraindications and adverse reactions of oral medicine , will not cause direct stimulation and damage to the internal organs. These kinds of external medicines are directly applied to the epidermis of the lesion, absorbed through the capillaries of the affected area, and directly act on the affected area to relieve heat and analgesia, but the sealing performance is poor. , easy to produce secondary pollution, uneven administration, easy to cause pain to the patient, not fast antipyretic and analgesic, etc.