136results about How to "Solve insoluble" patented technology

The invention discloses an assembling method of quantum point in the dielectric silica, which comprises the following steps: adopting SBA-15 as mould; making amino propyl trimethoxy silane to decorate dielectric silica; adding cadmium acetate; adsorbing Cd2+ in the channel to form SBA-15-Cd2+; reacting with TOPO, Se or Te; controlling reacting time to the grain size of cadmium selenide of quantum point of or cadmium telluride in the channel.

The invention provides ecoquinate soluble powder and a preparation method thereof. The preparation method comprises the steps: evenly mixing ecoquinate and a solid dispersion carrier together; heating the mixture to a fusing state at the temperature of 120DEG C to 150 DEG C; then, airing and crashing the mixture at room temperature; adding anhydrous dextrose to obtain the ecoquinate soluble powder. The decoquinate soluble powder comprises 1 percent to 20 percent of ecoquinate, 4 percent to 80 percent of solid dispersion carrier and anhydrous dextrose. The prepared soluble powder has good solubility and high stability, the property and the solubility of the soluble powder are not changed after being stored for 6 mouths under an accelerating test condition (40DEG C+ / -2DEG C) or being stored for 1 year at room temperature (25DEG C+ / -2DEG C ), the content of the ecoquinate soluble powder is reduced and meets the requirements of galenic pharmacy, the effective period of the ecoquinate soluble powder can be as long as 3 years by calculation, the content reduction is not obvious under an illumination experiment condition, and the content of drug active ingredients can be maintained above 90 percent for four hours in water. A prepared drug preparation has good effect and convenient use and has good popularization and application value.

A ticagrelor solid dispersion and preparation method thereof; the solid dispersion is prepared via dispersing the ticagrelor into a carrier material, the carrier material comprising one or more of polyvinylpyrrolidone, copovidone and crospovidone.

The invention discloses a syrup of and the preparation method thereof. The insolubleness and instability problems of desloratadine are successfully solved through addition of cosolvent and stabilizer, and the control of pH value. The syrup of antihistamines desloratadine can facilitate the oral-taking of patients with weak swallowing capability, has good taste and good stability.

The invention provides a determination method for calcium, cobalt, chromium and iron in tungsten carbide. The method employs inductively coupled plasma atomic emission spectrometry for determination of the content of calcium, cobalt, chromium and iron in tungsten carbide, and analytical ranges are as follows: Ca 0.005 to 2%, Co 1 to 15%, Cr 1 to 15% and Fe 0.005 to 10%. According to the invention, a tungsten carbide sample can be effectively dissolved, so the problem of difficult dissolution of the sample is overcome and a sample dissolution speed is accelerated; an optimal analytical line is found through interference experiments and spectrum analysis, interference among spectral lines is eliminated, accurate and reliable determination of the content of calcium, cobalt, chromium and iron in tungsten carbide is realized, and requirements of scientific research and production are met; and the method has the advantages of rapid measurement, easy and convenient operation and conservation of considerable manpower and material resources.

The invention relates to a glimepinride tablet preparation method, which comprises 1) glimepinride and microposer silica gel are ground with a micronizaion method, and the mixture powder of micronized glimepinride and microposer silica gel is obtained after passing through a screen of 80 to 100 mesh; wherein, the weight ratio of the glimepinride and microposer silica gel is 1: 1; 2) the mixture powder obtained in the step 1) is mixed with filling agent, disintegrant, lubricant, bond and 30 percent to 40 percent by volume concentration of ethanol solution for 15 minutes to 20 minutes in normal temperature, and passes through a screen with 18 to 24 meshes to obtain the particles. The particles adopts micronization technique to increase the surface area of slightly soluble main drug to facilitate glimepinride pulverization so that the wettability of the surface of the powder particles is improved and the dissolution of the raw medicine in tablets and the quality stability of the product during storage time are improved.

The invention relates to a manufacturing method of an organic thin-film transistor, which is suitable for the fields of the display, the sensor, the radio frequency identification (RFID) of a label, etc. The organic thin-film transistor has the structure that a grid (102), a gate insulator layer (103), a source cathode (104), a drain (105), a surface modification layer (106) and an organic semiconductor layer are arranged on a basement (101) in sequence. The preparation of the organic semiconductor layer can be realized via the transformation of pentacene derivatives to pentacene crystal. Through the adoption of the method, the organic semiconductor material is spin-coated and printed in a large area via solution. The manufacture of the organic thin-film transistor in large scale integration with a flexible substrate is accomplished, and the manufacture cost of the integrated circuit with the organic thin-film transistor can be reduced. Simultaneously, the surface modification layer is formed in the source cathode and the drain via OTS solution. The high mobility of the organic thin-film transistor, low leakage current and circuit working voltage can be further guaranteed.

The invention relates to a manufacturing method of organic thin-film transistors, which is suitable for the fields of the display, the sensor, the radio frequency identification (RFID) of a label, etc. The organic thin-film transistors include the structure that a grid (102), a gate insulator layer (103), a source cathode (104), a drain (105), a surface modification layer (106) and an organic semiconductor layer are arranged on a basement (101) in sequence. The preparation of the organic semiconductor layer can be realized via the transformation of pentacene derivatives to pentacene crystal. Through the adoption of the method, the organic semiconductor material is spin-coated and printed in a large area via solution. The manufacture of the organic thin-film transistors in large scale integration with a flexible substrate is accomplished, and the manufacture cost of the integrated circuit with the organic thin-film transistors can be reduced. Simultaneously, the surface modification layer is formed in the source cathode and the drain via the OTS solution. The high mobility of the organic thin-film transistors, low leakage current and circuit working voltage can be further guaranteed.

The invention provides a puerarin lagging cover slowly-releasing dripping pill which is formed by preparing puerarin quickly-releasing dripping pill core through slowly-releasing lagging cover, wherein the puerarin quickly-releasing dripping pill core is formed by preparing PEG6000 as matrix, and the proportioning by weight of puerarin to PEG6000 is 10:1-3:1. The invention also provides a method for preparing the slowly-releasing dripping pill. In the invention, puerarin is prepared into lagging cover slowly-releasing dripping pill, thereby remarkably increasing the dissolution to solve the problem of difficult dissolution, improving the oral bioavailability and achieves the aim of slow release by controlling the release through the lagging cover.

The invention relates to the technical field of photocatalytic materials, in particular to a preparation method and application of a perylene bisimide based organometallic polymer with visible-light photocatalytic performance.The preparation method includes the steps: 1, adding transition metal salt Tm and perylene bisimide derivative H2PDI in the molar ratio of 1:1.0-1.5 into a mixed solvent of N,N-dimethylformamide and water in the volume ratio of 1:2-2.5, and regulating the solution to alkalescence with NaOH; 2, putting the reaction solution prepared in the step 1 in an oven with the temperature controlled between 90 DEG C and 110 DEG C and time controlled between 60h and 80h, closing the oven, cooling to room temperature, crystallizing out, filtering and drying to obtain the target material Zn-PDI.The catalyst is simple to synthesize and easy to operate, the catalyst and the raw materials for catalytic reaction are low in cost, yield is high, visible-light photocatalysis can be realized under mild conditions, and convenience is brought to widespread popularization and application.

The invention provides a water-soluble cyclized metal iridium complex with a sugary ligand and application of the complex, wherein the cyclized metal iridium complex is generated by means of reaction between the sugary ligand and a chlorendic dikaryon iridium complex, can serve as an electrochemical luminescence and photoluminescence probe and is applied to detecting amine drugs in an aqueous solution system or used for biological markers. The cyclized metal iridium complex serving as the luminous probe is water-soluble and high in luminous quantum yield, solves the problem of a metal iridium luminous probe is insoluble in aqueous solution, and can be applied to analysis and test in aqueous solution.

The invention discloses tyrosinase inhibitor microemulsion as well as a preparation method and an application thereof, and belongs to the technical fields of foods, medicines and cosmetics. The microemulsion contains a matrix, a tyrosinase inhibitor norartocarpetin and water, wherein the matrix comprises 40%-60% of surface active agent, 20%-45% of cosurfactant and 5%-20% of oil phase; and the microemulsion is prepared by adding raw components according to a certain ratio. The tyrosinase inhibitor microemulsion can be used for overcoming the defects that the solubility of the natural tyrosinase inhibitor norartocarpetin in water is extremely low. The method provided by the invention is simple to operate and can be used for the spontaneous formation of the microemulsion. Nanoscale microemulsion can be formed by using water or an aqueous solution for diluting the tyrosinase inhibitor microemulsion. The obtained microemulsion can be used for effectively resisting enzymatic browning of fruits and vegetables, and preparing whitening cosmetics and other medicines for preventing and treating human hyperpigmentation diseases and melanomas (caused by excessive melanin) needing to inhibit the activity of tyrosinase.

The invention relates to a butylphthalide controlled release preparation and a preparation method thereof. Drugs can be uniformly released at a constant speed, and release of liquid drugs from the controlled release preparation in a liquid form is achieved.

This invention relates to a compound material for suppressing growing of alga including a carrier with porous basic substance and a nm metal mixture covering the carrier, in which, said mixture includes nm metal particles and a substance fixing the particles on the carrier. This invention further provides a method for suppressing the growing of alga.

The invention discloses a tyrosinase inhibitormicro-emulsion and a preparation method and an application of the tyrosinase inhibitor micro-emulsion, and belongs to the technical fields of foods, medicines and cosmetics. The micro-emulsion comprises a ground substance, tyrosinase inhibitors including steppogenin and artocarpanone, and water, wherein the ground substance comprises 45%-60% of surfactant, 20%-30% of cosurfactant and 10%-30% of oil phase. The micro-emulsionis prepared from various materials according to certain ratios. The defect of extremely low solubility of the tyrosinase inhibitors including steppogenin and artocarpanone in the water is overcome, the method which is simple in operation and can spontaneously form the micro-emulsion is provided, and the water or an aqueous solution is used for dilution so as to prepare the micro-emulsion with nanoscale grain size. The prepared micro-emulsion can be effectively used for preventing enzymatic browning of fruits and vegetables, preparing skin whitening cosmetics, preventing and treating chromatosis diseases and melanoma of a human body that are caused by excessive melanin, and preparing other medicines requiring inhibition of the tyrosinaseactivity.

The invention discloses aperture-controllable bacterial cellulose porous microspheres and a preparing method for the aperture-controllable bacterial cellulose porous microspheres. Bacterial cellulose is taken and dissolved in a solvent, a bacterial cellulose solution is obtained, template particles with different particle sizes are added in the bacterial cellulose solution, the mixture is put in an ultrasonic dispersing machine, the particles are evenly dispersed through ultrasonic treatment, and a dispersed solution is obtained; the dispersed solution and a surfactant are poured into an organic solvent for homogeneous emulsification, a w / o type bacterial cellulose emulsion is obtained, a precipitating agent is added in the bacterial cellulose emulsion and stirred, and microsphere suspension liquid is obtained; the microsphere suspension liquid is subjected to vacuum filtration, precipitate is collected and washed with n-butyl alcohol, acetone and acetone three times in sequence, the washed precipitate is then extracted with ethyl alcohol, precipitate is collected and subjected to frozen drying, and the aperture-controllable bacterial cellulose porous microspheres are obtained. The method has the advantages of being low in cost, simple in process, capable of facilitating industrialized production and the like, the stability and repeatability are good, the aperture of the bacterial cellulose porous microspheres ranges from 200 nanometers to 50 micrometers, and the bacterial cellulose porous microspheres are suitable for mass production.

The invention provides a cornua cervi pantotrichum polypeptide serial extraction method beneficial to skin or mucosa absorption. A weak acid solution is adopted for extracting cornua cervi pantotrichum natural polypeptide, residual byproducts are subjected to enzymolysis by adopting neutral protease, ultrafiltration and refining are combined, so that the cornua cervi pantotrichum polypeptide is extracted, and higher solubility is obtained. The extracted cornua cervi pantotrichum polypeptide is close to a pH tolerance value of human skin, higher solubility can be easily obtained in preparation of a product, and stimulation of pH value of the polypeptide, extracted by adopting the method provided by the invention, to skin is small. An acidolysis-enzymolysis two-step method is adopted for extracting the cornua cervi pantotrichum polypeptide, extraction ratio of the cornua cervi pantotrichum polypeptide is greatly increased, utilization ratio of raw materials is higher, extraction rate of polypeptide below 1000Da is increased to 2.64% from 0.44%, and polypeptide prepared through enzymolysis by virtue of the byproducts of the cornua cervi pantotrichum polypeptide has biological activity; hierarchical ultrafiltration refining is adopted, molecular weight of 90% of the prepared polypeptide is lower than 1000Da, and the prepared polypeptide is beneficial to absorption of skin and mucosa of human; wide-range application of the cornua cervi pantotrichum polypeptide in cosmetic or external skin preparation is provided.

The invention relates to a flexible inorganic solid-state electrolyte thin film and preparation and application thereof. The flexible inorganic solid-state electrolyte thin film is prepared by compounding graphite oxide and Li6.75La3Zr1.75Nb0.25O12LLZN inorganic solid-state electrolyte particles through electrostatic adsorbent lithium ions. The preparation comprises the following steps of uniformly dispersing an LLZN dispersing liquid, pouring onto a sand core with a filter film, sucking and filtering, then pouring a graphite oxide dispersing liquid, sucking and filtering under the vacuum condition, and drying, so as to obtain the flexible inorganic solid-state electrolyte thin film. The flexible inorganic solid-state electrolyte thin film has the advantages that the preparation method issimple, the cost is low, and the industrialization is easy; the weight of the prepared flexible inorganic solid-state electrolyte thin film is light, the flexibility is good, the ion conductivity is good, and the excellent safety property is realized; the application prospect is broad in the fields of flexible electron energy storage devices, flexible sensing, flexible display and the like.

The invention discloses an astaxanthin nanometer preparation prepared by an electrostatic spraying method and a preparation method thereof, and relates to the field of nanometer drug preparations. Theastaxanthin nanometer preparation consists of astaxanthin, a nuclear layer carrier and a shell layer carrier; a drug, a hydrophilic polymer carrier and an absorption promoting component are dissolvedin a nuclear layer mixed solvent; the hydrophilic polymer carrier is dissolved in water, and the astaxanthin solid nanometer preparation is prepared by the hydrophilic polymer carrier and the absorption promoting component by adopting the coaxial electrostatic spraying method. The mass ratio of the astaxanthin to the hydrophilic polymer carrier to the absorption promoting component in a nuclear layer solution is 1 to 0-8 to 2-4; the total concentration of the hydrophilic polymer carrier and the absorption promoting component in the nuclear layer solution is 0.2-1.2 percent (w / v); the total concentration of the shell layer carrier is 0.6-2.6 percent (w / v). The volume ratio of the nuclear layer solution to a shell layer solution is 1 to 1 (v / v). The astaxanthin nanometer preparation and thepreparation method thereof disclosed by the invention have the benefits that the solubility of the astaxanthin is significantly increased, the in-vitro drug release rate of the astaxanthin is improved, and the oral bioavailability is improved; the astaxanthin nanometer preparation is simple in process and high in degree of industrialization; the prepared astaxanthin solid nanometer preparation isuniform in particle size and stable in character, thereby having a better application prospect.

The invention discloses a preparation method for lithium ion battery cathode material ferric niobate. The method comprises the following steps: respectively dissolving columbium pentachloride and ferric salt at stoichiometric ratio as shown in the chemical formula of ferric niobate in absolute ethyl alcohol and uniformly stirring and mixing; dropwise adding ammonium hydroxide at constant speed till the pH value of the mixed solution is within 9-9.5 and keeping at room temperature; after completing dropwise adding, continuously stirring for 8-16h, and then centrifugally washing and drying, thereby acquiring a precursor hydroxide of the material; grinding the precursor hydroxide and sintering for 6h at 900 DEG C. The method for preparing the ferric niobate is simple in steps, is convenient for industrial mass production, can acquire fine and uniform compounded product particles and can guarantee the circulation capacity and electrochemical performance of the material.

The invention discloses self-foaming acne cleaning and oil controlling facial cleansing foam containing a hemp extract and a preparation method thereof. The facial cleansing foam contains 0.1%-3.0% ofthe hemp extract, 2.0%-20.0% of dipropylene glycol, 2.0%-30.0% of decyl glucoside, 0.001%-0.3% of a pH regulator, and 47%-93% of water. The facial cleansing foam of the invention has the advantages of transparent appearance, high content of the hemp extract, rich foam, easy rinse and no skin tight after cleansing, has the efficacy of antibacterial and anti-inflammatory, and especially has a goodinhibitory effect on Gram-positive anaerobic bacteria such as propionibacterium acnes.

The invention provides an etoricoxib gel preparation and a preparation method thereof. The gel preparation comprises the following components in percentage by weight: 0.3 to 10% of etoricoxib, 0.3 to 25% of carbomer 940, 0.1 to 30% of tromethamine, 1 to 45% of ethyl alcohol, 5 to 50% of propylene glycol, 0.5 to 5% of polyethylene glycol 400, 0.05 to 0.8% of edetate disodium, 1.0 to 10% of triethanolamine, and the balance of pure water. According to the preparation method, tromethamine is used to dissolve etoricoxib so as to solve the problem that etoricoxib is hardly dissolved in water; the skin penetrability of etoricoxib is improved and the transdermal absorption rate of etoricoxib is increased, and local external application of the gel preparation can obviously improve the treatment effect on arthritis or rheumatoid arthritis; simultaneously, a new administration route is provided for patients. The gel preparation is in a form of semi-solid gel with good transdermal absorption effect etoricoxib is completely dissolved and dispersed in the gel preparation, and thereby the pain of the patient can be relieved favorably. The preparation method is simple in process, and the preparation is stable and reliable in quality.

The invention provides an etching solution for a glass substrate thinning technology. The etching solution is prepared from the following raw materials in percentage by weight: 1 to 5 percent of HF (Hydrogen Fluoride), 10 to 25 percent of fluoride, 5 to 10 percent of strong acid, 1 to 5 percent of ethylenediamine tetraacetic acid (EDTA) or ethylenediamine tetraacetic acid salt (EDTA salt), 1 to 2percent of a surfactant, 1 to 2 percent of ethanol and the balance of water. According to the etching solution for the glass substrate thinning technology, a formula is optimized and the dosage of hydrofluoric acid is reduced; meanwhile, certain beneficial auxiliary agents are added, so that negative problems caused by the HF are avoided and an etching effect is good.

The invention discloses a Ginkgolide B powder injection, which is characterized in that: it is a powder injection consisting of main medcine and pharmacological acceptable filter aid, excipient and stabilizer. Said main medicine is Ginkgolide B, and filter aid is meglumine, and excipient is mannitol or dextran 40, and stabilizer is EDTA-2Na or EDTA-CaNa. The weight ratio is: Ginkgolide B:EDTA-2Na or EDTA-CaNa:mannitol or dextran 40 = 1:0.5-3:0.01-2:1-20. The preparation solves the problems such as Ginkgolide B indissolvable problem, redissolve clarity and stability.

The invention relates to an EKS and acrylic two-ingredient blend fiber product quantitative chemical analysis method, which is characterized by sequentially comprising the following steps of 1, performing original test sample pretreatment to obtain dry and pure test samples; 2, wetting the test samples by a sodium hypochlorite solution; 3, putting the test samples into a water bath being 80 to 120DEG C for heating; 4, taking residual fiber; performing suction and filtering in a sand core crucible; then, flushing the sand core crucible by a small quantity of sodium hypochlorite solution; 5, taking residual fiber; adding dilute acetic acid for neutralization; 6, taking the residual fiber; then, performing suction and drying by the sand core crucible; flushing the sand core crucible by clearwater; 7, performing drying and cooling to obtain the final residual fiber. A sodium hypochlorite dissolution method is used for completing the quantitative analysis; the operation is simple; the test stability is high; the environment pollution and the harm to the human body are low; the test result balance performance is good; the errors are small.

The invention relates to a preparation method of low-dielectric polyimide fibers. The preparation method comprises the steps that benzocyclobutene diamine, heterocyclic diamine and a polar aprotic solvent are mixed and stirred; aromatic dianhydride is added in to the mixture, and a polymerization reaction is conducted; and the obtained soluble polyimide solution is subjected to deaeration and spinning and then subjected to heat drawing treatment. The low-dielectric polyimide fibers obtained through the method have the characteristics of low dielectric constant, low water absorption rate, stable size and the like, and can be applied to the fields of wave-transparent composite materials, flexible electronic substrates, wearable devices and the like; and certain functionality is given to thefibers, and the application range of the material can be further expanded.

The invention discloses a peculiar-smell-free high-adhesion polyurethane composition, and relates to the technical field of polyurethane preparation. The peculiar-smell-free high-adhesion polyurethanecomposition contains 100 parts of a polymer polyether polyol, 20-40 parts of a polyisocyanate, 2-5 parts of a cross-linking agent, 1-5 parts of a foaming agent, 1-2 parts of a catalyst, and 0.5-2 parts of an antifoaming agent with an average molecular weight of 800-1200. The invention also provides a preparation method and equipment thereof. By synchronously improving the material components, theprocess and the equipment, the problems of sufficient reaction among the materials, provision of adhesive property and elimination of peculiar smell are solved, the material strength is improved, andthe reaction is sufficient and thorough, so that the peculiar smell generated by insufficient reaction of the raw materials is eliminated. The problem of insolubility of high-molecular polyether andlow-molecular polyether is solved, multiple catalysts are selected, the catalytic activity difference of each catalyst is different, foaming and gel are balanced in the early-stage foaming stage, gelreaction is conducted in the later stage, materials can be cured and cross-linked within set time at low temperature, and the material strength is improved.

The invention relates to an ibuprofen fat emulsion injection which is prepared from the following components in parts by weight: 50-150 parts of ibuprofen, 800-1,200 parts of soya bean oil, 60-120 parts of ovolecithin and 220-260 parts of glycerol; the water is injected for supplementation to 1,000 mL. According to the invention, the homogeneous-phase liquid ibuprofen fat emulsion injection is prepared by adopting a drug-loaded fat emulsion form, uniform emulsion droplet particles are formed in the long-term placing process of the ibuprofen fat emulsion injection, and stability and safety are higher.

The invention relates to a low solid-content accelerator and a preparation method thereof, which relate to a concrete additive, and especially relates to the low solid-content accelerator. The invention also relates to the preparation method of the accelerator. The low solid-content accelerator takes active aluminium hydroxide, aluminum sulfate, sodium silicate, sodium carbonate, sodium hydroxide,deionized water, and triisopropanolamine as raw materials for a reaction, and the above raw materials are subjected to a reaction to prepare mother liquor of the low solid-content accelerator; thickening agents such as sodium polyacrylate and maltodextrin as well as a stabilizing agent cellulose ether MF4 are added as a reaction auxiliary agent during usage of the mother liquor, the solid contentof the accelerator through complex formulation is 35%, an application amount of the low solid-content accelerator is reduced during usage, production usage cost can be greatly reduced, and the earlystage intensity of the concrete and the usage intensity at a later stage cannot be influenced.

The invention discloses an assembling method of quantum point in the dielectric silica, which comprises the following steps: adopting SBA-15 as mould; making amino propyl trimethoxy silane to decorate dielectric silica; adding cadmium acetate; adsorbing Cd2+ in the channel to form SBA-15-Cd2+; reacting with TOPO, Se or Te; controlling reacting time to the grain size of cadmium selenide of quantum point of or cadmium telluride in the channel.