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External medicine composition preparation with anti-inflammation detumescence pain-easing function

A technology of externally used drugs and compositions, applied in the field of externally used pharmaceutical composition preparations, which can solve the problems of contaminated clothes, ulcers, oil leakage, etc.

Active Publication Date: 2013-05-01
JIANGSU KANION PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Because of its definite curative effect, convenient use, and low price, black plaster has a wide base of use among Chinese folks. However, because the preparation of plaster is more based on experience, there is a lack of controllable process parameters and quality standards in production, and the product quality is uneven. , not suitable for large-scale industrial production, and it is easy to cause oil leakage, oil leakage, and contamination of clothes
Due to the large compound prescriptions used in traditional Chinese medicine, the drug loading capacity of the rubber ointment is limited, and the curative effect is greatly affected
[0004] Aescin (or its pharmaceutically acceptable salt) is mostly used for injection clinically. Due to its own nature, it has obvious irritation to blood vessels and causes great pain to patients. It has to be shortened in the course of treatment. time, thus affecting the effectiveness of the treatment
Non-steroidal analgesic and anti-inflammatory drugs are mostly taken orally, which has the obvious disadvantages of gastrointestinal irritation, gastrointestinal bleeding and ulcers

Method used

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  • External medicine composition preparation with anti-inflammation detumescence pain-easing function
  • External medicine composition preparation with anti-inflammation detumescence pain-easing function
  • External medicine composition preparation with anti-inflammation detumescence pain-easing function

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0076] Example 1. A medicinal composition for external use with anti-inflammatory, detumescence and analgesic effects, the active ingredient raw materials of the medicine and the percentage by weight that account for the whole preparation are:

[0077] (1) Aescin or its pharmaceutically acceptable salt 0.01%;

[0078] (2) 0.01% of any one of ketoprofen, tilofenac, the pharmaceutically acceptable salts of tilofenac, meloxicam, piroxicam and naproxen;

[0079] The rest are excipients. It can be used for the treatment of local muscles, joints, nerve inflammation and pain.

Embodiment 2

[0080] Example 2. A medicinal composition for external use with anti-inflammatory, detumescence and analgesic effects, the active ingredient raw materials of the medicine and the percentage by weight that account for the whole preparation are:

[0081] (1) 20% of aescin or a pharmaceutically acceptable salt thereof;

[0082] (2) 10% of any one of ketoprofen, tilofenac, the pharmaceutically acceptable salts of tilofenac, meloxicam, piroxicam and naproxen;

[0083] The rest are excipients. It can be used for the treatment of local muscles, joints, nerve inflammation and pain.

Embodiment 3

[0084] Example 3. A medicinal composition for external use with anti-inflammatory, detumescence and analgesic effects, the active ingredient raw materials of the medicine and the percentage by weight that account for the whole preparation are:

[0085] (1) Aescin or its pharmaceutically acceptable salt 1%;

[0086] (2) 1% of any one of ketoprofen, tilofenac, tilofenac in pharmaceutically acceptable salts, meloxicam, piroxicam and naproxen;

[0087] The rest are excipients. It can be used for the treatment of local muscles, joints, nerve inflammation and pain.

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Abstract

The invention relates to an externally-used medical compound preparation having the functions of being anti-inflammatory, antipyretic and analgesic. The preparation is characterized in that the preparation is prepared by the following raw materials of active ingredients with the following weight percentages: 0.01 percent to 20 percent of aescin or salts thereof acceptable in pharmacy, 0.01 percent to 10 percent of one or more of ketoprofen, tiaprofenic acid, tiaprofenic salts acceptable in the pharmacy, meloxicam, piroxicam and naproxen, and the rest amount of accessories. The externally-usedmedical composition can be used for preparing any externally-used preparation acceptable in the pharmacy. The preparation of the invention can be used for treating arthrodynia, hyperosteogeny, gout, neuropathic pains, traumatic injuries, chronic eparsalgia, various closed injuries and other diseases, and has strong practicability.

Description

technical field [0001] The present invention relates to an external pharmaceutical composition preparation made of natural medicine and non-steroidal analgesic and anti-inflammatory drug; especially an external pharmaceutical composition preparation with anti-inflammatory, swelling and analgesic effects; the present invention also Involves the use of the preparation. Background technique [0002] Arthralgia, hyperosteogeny, gout, neuropathic pain, bruises and various closed injuries are common and frequently-occurring diseases, which seriously affect people's work, study and daily life. Although there are many Western medicines, most of them have side effects in varying degrees, so sticking and applying externally applied medicines are the easiest and most popular methods for treating the above-mentioned diseases. [0003] At present, there are many kinds of external preparations with anti-inflammatory and analgesic effects. Western medicines are mainly non-steroidal analge...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/704A61K36/185A61K9/00A61P19/02A61P19/06A61P19/10A61P25/02A61K31/192A61K31/381A61K31/5415A61K131/00
Inventor 丁岗曹亮张艳海孟兆青陈俊施敏倪玮烨
Owner JIANGSU KANION PHARMA CO LTD
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