2428 results about "Anti inflammation" patented technology

This invention discloses new krill oil compositions characterized by having high amounts of phospholipids, astaxanthin esters and/or omega-3 contents. The krill oils are obtained from krill meal using supercritical fluid extraction in a two stage process. Stage 1 removes the neutral lipid by extracting with neat supercritical CO₂ or CO₂ plus approximately 5% of a co-solvent. Stage 2 extracts the actual krill oils by using supercritical CO₂ in combination with approximately 20% ethanol. The krill oil materials obtained are compared with commercially available krill oil and found to be more bioeffective in a number of areas such as anti-inflammation, anti-oxidant effects, improving insulin resistances and improving blood lipid profile.

An internal dry powder delivery system through a working channel of an endoscopic cannula for directly applying the powder form medication to an internal tissue/organ site, includes an elongated tubular delivery channel and a powder supply device for producing pressurized gas mixing with the dry powder for feeding to form a mixture of dry powder and pressurized gas delivering to an internal tissue/organ site through the delivery channel via endoscopic cannula. It ensures a smooth powder release by preventing liquid from accumulation at the tip of the delivery channel and offers physicians a new powder form drug delivery method via endoscope. Also, it offers new minimal invasive application by directly and precisely applying the powder format drug to the internal sites of human gastrointestinal organ via endoscope to achieve hemostasis, anti-inflammation, anti-ulcer and anti-tumor treatment, etc.

The present invention discloses a preparation method of an antiphlogistic and antisticking stanching sponge. The preparation method includes the following steps: through the cross linking of polyvinyl alcohol, chitosan gel microspheres are fixed on the inner wall of a sponge, the sponge is then soaked in antiphlogistic solution and antisticking solution, and finally, the PVA/drug-loaded chitosan antiphlogistic and antisticking stanching sponge is prepared. The antiphlogistic and antisticking stanching sponge prepared by the method can be trimmed according to the size of an operative cavity in order to be placed into the corresponding part, the pressure on the circumference is uniform, blood can be thoroughly stanched, and the injury on the mucous membrane of the operative cavity is little. The antiphlogistic and antisticking stanching sponge prepared by the method, which has good antiphlogistic, stanching and antisticking functions, biocompatibility, and mechanical and anti-oedema properties, can promote the injured tissues to have strong recovering capability, prevent rebleeding and avoid the inevitable potential virus hazard caused by glutin and animal collagen proteins, so the use safety is greatly improved, and moreover, the antiphlogistic and antisticking stanching sponge can alleviate the pain and discomfort suffered by patients. The antiphlogistic and antisticking stanching sponge is expected to substitute the import products and have remarkable social and economic benefits.

The present disclosure relates to drug eluting devices, and their uses. The drug eluting devices can allow for perfusion during deployment. The coatings the may contain bioactive materials which elute once deployed in a patient and can have anti-proliferative, anti-inflammation, or anti-thrombotic effects. Sol gel technology can be used to coat the devices.

The invention discloses an anti-inflammation active component group of a stomatitis clearing preparation and an analysis method. Fingerprint characteristic spectra of the component group are constructed and are applied to detecting the quality of the stomatitis clearing preparation. The analysis method which is a quality detecting method particularly includes detecting the quality of the stomatitis clearing preparation by the aid of a detection index which is anti-inflammation efficacy; uniformly designing difference samples with different component proportions; acquiring fingerprint characteristic data of the difference samples by the aid of UFLC-Q-TOF-MS/MS (ultrafast liquid chromatography-quadrupole-time of flight-mass spectrometry/mass spectrometry) technologies; acquiring anti-inflammation activity data of the preparation. The relevance between chemical components of the difference samples and the efficacy is comprehensively analyzed by the aid of the mathematical statistics method, accordingly, 29 anti-inflammation efficacy active components can be determined, and the fingerprint characteristic spectra of the component group can be constructed. Compared with the prior art, the anti-inflammation active component group and the analysis method have the advantages that the active component group is analyzed on the basis of the relevance between the spectra and the efficacy, accordingly, the quality of raw medicinal materials, semi-finished products and finished products can be directly, objectively, scientifically and comprehensively monitored in production procedures, and the effectiveness and the quality consistency of the products can be guaranteed.

An apparatus for ablating deposits along the blood vessel of human and animals is disclosed. The apparatus has an extracting and pressurizing unit for extracting blood from a supply vessel and pressurizing it plus a downstream delivering and injecting unit for delivering and injecting the filtered and pressurized source blood into a blood vessel under treatment. Besides inducing a blood circulation and having ablation devices like ultrasound and RF heating, the apparatus ablates the deposits from a nearby portion of the vessel. The characteristics of selective ablation and self-termination make the proposed apparatus safe and effective in treating early-stage atherosclerosis. A DC discharging device can be included to neutralize excess surface charge generation on the wounded healthy tissues following ablation for disinfection and anti-inflammation. Placement of the blood extracting point just downstream of the blood injecting point insures thorough collection and removal of blood-clogging plaque and calcification fragments.

The invention relates to an aroniamelanocarpa fruit wine and a brewing method thereof. The fruit of aroniamelanocarpa is taken as raw material and is made into fruit juice, fruit wine microzyme is selected for use and put into the fruit juice according to the proportion being 5-10% of the weight of the fruit juice, and the aroniamelanocarpa fruit wine is brewed with the alcohol content of 5-13% (v/v) and the total sugar content of 4.0-80.0g/L. The brewing technique of the invention comprises preparing the fruit juice, inoculation and fermentation, aging and store maturity, purifying wine body as well as filtration and sterilization, and the most advanced fermenting and purifying technique can be adopted by the production. The product of the invention has unique flavor, slightly acerbic and fresh taste, mellow mouthfeel, pleasing aroma and wide applicable people. The fruit wine contains multiple nutritional functional components such as anthocyanin, flavone, polyphenol active substance, vitamins antioxidant, mineral composition, polyoses, organic acid and the like which are rich in the fruit of aroniamelanocarpa, and has good effects of oxidation resistance, ageing prevention, blood pressure regulation, vessel relaxing, blood-fat reduction, anti-inflammation and detoxification, radiation resistance, etc.

The present invention is concerned with an anti-inflammation analgesic preparation which contains a specific 3-0-substituted ascorbic acid as an active ingredient, shows excellent anti-inflammation analgesic effects and is excellent in shelf life, safety to a skin and endermic absorptivity of the active ingredient.

The present invention discloses a drug 'Jinling Xiaoyan Oral Liquor' made up by using 23 Chinese medicinal materials of toosendan fruit, corydalis tuber, codonopsis root, atractylodes root, white poria and others. It can be used for effectively curing acute and chronic gastritis, peptic ulcer, acute and chronic hepatitis, chelecystitis and pancreatis, etc. and its therapeutic effect is reliable.

Present invention features a novel use of Lactobacillus for treating type 2 diabetes, wherein the Lactobacillus is Lactobacillus reuteri GMNL-89 with the deposition numbers of BCRC 910340 and CCTCC M 207154 and comprises of live, dead bacteria or supernatant of the bacterial culture(s) and a pharmaceutically acceptable vehicle. The invention also discloses the efficacies of the indicated Lactobacillus strain including anti-oxidative enzyme activity, anti-inflammation, reduction of blood glucose level, reduction of triglycerides, reduction of total cholesterol, reduction of LDL, increase of HDL and improve insulin utilization.

The invention discloses a cosmetic composition with an acne treatment function and a preparation method thereof.The cosmetic composition comprises, by weight, (a) 2-20% of humectants, (b) 0.05-5% of thickener, (c) 2-15% of emollient, 0.02-3% of emulsifier, (e) 0.5-5% of anti-inflammatory agent, (f) 2-20% of skin conditioner, (g) 0.01-0.1% of essential oil and (h) 30-90% of deionized water.By the cosmetic composition, the problems of excessive sebum secretion, keratosis follicularis, pore blockage, acne related bacterial infection and oil degradation resulting in inflammation are solved, and the efficacy of bacteriostasis, anti-inflammation and oil control is achieved.

The invention belongs to the technical field of extraction of Chinese herbal medicine, and particularly relates to a herba centellae extract with anti-inflammation and anti-sensitivity effects. The herba centellae extract is prepared by adopting the following preparation method: S1. adding ethanol into herba centellae powder for extraction, carrying out ultrasonic assisted extraction, then centrifuging or filtering, and collecting a filtrate; S2. adding activated carbon to the filtrate obtained in step 1 for decoloring, centrifuging, and collecting a decolored filtrate; S3. concentrating the decolored filtrated obtained in step 2, adding a chitosan liquid for decontamination, filtering, and collecting a decontaminated filtrate; S4. adding macroporous adsorption resin to the decontaminated filtrate for purification, and eluting with ethanol to obtain an eluent; S5. concentrating, desalting and drying the eluent obtained in step 4 to obtain the herba centellae extract, wherein in S1, the concentration of ethanol is 60-90%, the ultrasonic power is 228W-380W, and the material-to-liquid ratio is 1:20-80. The herba centellae extract provided by the invention has remarkable anti-inflammation and anti-sensitivity effects, is prominent in oxidation resistant and free radical removal effects, and can be widely applied to skin care products with anti-inflammation and anti-sensitivity effects.

The invention discloses nutrient gel for sterilizing and healing a wound surface and belongs to the technical field of anti-bacteria gel. The nutrient gel for sterilizing and healing the wound surface is prepared from hydroxyethyl cellulose, chitosan and derivatives thereof, guanidine polymers, glycerinum and compound amino acid. The hydroxyethyl cellulose serves as a gel substrate, the gel which is used for sterilizing and healing the wound surface and contains the guanidine polymers, the chitosan and derivatives thereof and the compound amino acid is prepared through a simple process, and the nutrient gel has good skin compliance, is non-irritant, has sterilization and anti-inflammation functions, provides a certain nutrition support for the wound surface, effectively promotes healing and recovery of the wound surface, has no side effects and is safe and environment-friendly.

The invention discloses an oxidation chitosan graft modified porcine dermal collagen micro-nano fiber membrane and a preparation method thereof. The oxidation chitosan graft modified porcine dermal collagen micro-nano fiber membrane is characterized in that the preparation method comprises the steps: by applying an electrostatic spinning technology and using traceable purified porcine dermis as a raw material and hexafluoroisopropanol as a solvent, stirring at 4-10 DEG C until the mixture is transparent, formulating to obtain electrostatic spinning mother liquor with concentration of 0.5-10%, and directly spinning to obtain the porcine dermal collagen micro-nano fiber membrane; then performing graft modification on the porcine dermal collagen micro-nano fiber membrane by using oxidation chitosan, thereby finally obtaining the oxidation chitosan graft modified porcine dermal collagen micro-nano fiber membrane. A membrane material not only has good bio-compatibility, biodegradability and mechanical properties, but also has anti-oxidation effects, antibacterial activities, anti-inflammation/wound healing promotion effects, anti-cancer/anti-tumor effects and antiviral effects of chitosan, is significantly better than a collagen composite membrane material prepared by using collagen as the raw material, and can be widely applied to the preparation of biomedical materials such as hemostatic materials, tissue engineering scaffold materials, biological dressings and the like.

The invention relates to the technical field of hyaluronic acid products, in particular to a hyaluronic acid mouth care film. The dry film contains the following components in percentages by weight: 10% to 50% of sodium hyaluronate, 10% to 40% of zinc hyaluronate and 10% to 40% of hydrolytic sodium hyaluronate. Hyaluronic acid and derivatives thereof are taken as film-forming materials of the mouth film, so that the mechanical property of the film is obviously improved, and the flexibility is strengthened; the hyaluronic acid and derivatives thereof are taken as main active ingredients of the mouth film and have various biological activities, and the hyaluronic acid has the effects of relieving release, promoting absorption and synergistically interacting for other added active ingredients; besides the biological activities of sodium hyaluronate, the zinc hyaluronate has higher anti-bacteria and anti-inflammation effects, and is more beneficial to mouth health, mouth disease prevention and treatment and throat nursing; the product disclosed by the invention is light in weight, small in size and convenient to carry and transport.

The invention provides an anastomat for gastrointestinal tract anastomosis surgery and a production method thereof. The anastomat comprises an anastomosis nail and a base and is divided into two types, namely a combined type and an independent type. The anastomat is composed of degradable materials and medical barium sulfate and can be finally disintegrated to be powder to be removed from the body after being used up. An envelope is formed on the outer surface of the anastomat through polyacrylic resin and contains medicines such as sulfonamides and quinolones antisepsis and anti-inflammation medicines and adrenobazonum, dicynone and other hemostasis medicines, and the envelope can selectively perform medicine slow release and controlled release according to different pH physiological environments of gastrointestinal tracts.

The invention discloses a method for synthesizing a novel tetracyclic diterpene compound from stevioside, which is cost-efficient and feasible. The compound is represented by a general formula (I), wherein the definitions of R1, R2, X, Y are shown in the specification. The invention discloses a potential application value of the compound in the aspects of anti-tumor and anti-inflammation and a detailed preparation method of the compound as well as physical data of Fourier transform infrared spectroscopy (FT-IR), hydrogen nuclear magnetic resonance spectroscopy (1 HNMR), mass spectrometry (MS) and the like.

The invention discloses compound plant essential oil with effects of repelling mosquitos, relieve itching and subsiding swellings. The compound plant essential oil comprises the following raw materials: artemisia vulgaris oil, lemon essential oil, eucalyptus citriodora oil, clove essential oil, camellia seed essential oil, catnip essential oil, thyme essential oil, geranium essential oil, rosemaryessential oil, castor oil, citronella oil, litsea oil, lavender essential oil, lithospermum essential oil, clary sage essential oil, mentha spicata essential oil, cypress essential oil, platycladus orientalis essential oil, calendula officinalis essential oil, cedarwood essential oil, juniper berry essential oil, wild chrysanthemum essential oil, leonurus japonicus essential oil, eucommia ulmoides essential oil, jasmine essential oil, eucalyptus essential oil, valeriana officinalis essential oil, rose essential oil, osmanthus fragrans essential oil and lemongrass oil. The compound plant essential oil has obvious mosquito repelling effect, high itching relieving and swelling subsiding speeds, remarkable improvement effects on eczema improving suppuration, herpes, pimples, swelling furuncleand itching skin as well as obvious anti-bacterial and anti-inflammation functions.

The invention discloses a skin care composition which comprises at least one component for promoting blood circulation to remove blood stasis, at least one antisepsis and anti-inflammation component, at least one skin conditioner and at least one muscle generation skin care agent according to the mass ratio of (0.1-50):(0.1-30):(0.1-80):(0.1-30), wherein the component for promoting blood circulation to remove blood stasis is one or a combination of several of ginger juice, snake oil, a radix angelicae extract, a nux vomica extract, a natural copper extract, a sangusis draconis extract, a caulis spatholobi extract, frankincense essential oil, myrrh essential oil, sesame oil, sheep suet, salviae miltiorrhizae, radix notoginseng, a red peony root extract, trogopterus dung, safflower oil, lithospermum essential oil, an angelica sinensis extract, puffball powder, plant soot, orange peel and lavender essential oil. The invention also provides a facial tissue with the skin care composition. The facial tissue can be carried by a user and is used for nursing and improving a chilblain affected part, and the skin improving effect at the affected part is obvious.

The invention discloses clove compound mouthwash, which comprises the following ingredients in percentage by mass: 0.2 to 0.4 percent of tea polyphenol, 0.5 to 1 percent of eugenol, 0.17 to 0.2 percent of pseudo-ginseng extracts (20:1), 3 to 6 percent of active ingredient stabilizing agents, 0.5 to 1 percent of active ingredient regulating agents, 0.1 to 1 percent of sweetening agents, 0.02 to 1 percent of sour agents, 2 to 5 percent of wetting agents, 0.5 to 1 percent of essence, 0.05 percent of fluoride, 0.01 to 0.4 percent of edible antiseptics and the balance deionized water, wherein the tea polyphenol, the eugenol and the pseudo-ginseng extracts are active ingredients in the mouthwash. The eugenol has the inhibition effect on the pathogenic bacteria and the fungi, a certain antioxidation effect and a certain anti-cancer effect are also achieved, the flavor is unique, the anti-bacterium and anti-oxidation effects of the tea polyphenol are also very good, the tea polyphenol is widely applied to toothpaste, the pseudo-ginseng has better blood circulation promotion and anti-inflammation effects, and a good inhibition effect is achieved on major harmful bacteria in oral cavity resident flora.