Anastomat for gastrointestinal tract anastomosis surgery and production method thereof

A stapler and gastrointestinal tract technology, applied in the field of medical devices, can solve the problems of increasing the scarring of the anastomosis, narrowing and obstruction of the intestinal lumen, unfavorable intestinal peristalsis, and reducing the elasticity of the gastrointestinal tract, etc., so as to improve the success rate of surgery, Effect of reducing wound infection and reducing treatment cost

Active Publication Date: 2013-08-14
HANGZHOU MEDZONE BIO-TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, after the surgery is cured, the leftover metal titanium nails will affect postoperative X-ray, CT, MRI and other examinations.
At the same time, titanium nails remain on the periphery of the suture site, which reduces the elasticity of the gastrointestinal tract, is not conducive to intestinal peristalsis, and increases the chances of anastomotic scarring and intestinal stenosis and obstruction

Method used

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  • Anastomat for gastrointestinal tract anastomosis surgery and production method thereof
  • Anastomat for gastrointestinal tract anastomosis surgery and production method thereof
  • Anastomat for gastrointestinal tract anastomosis surgery and production method thereof

Examples

Experimental program
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Effect test

preparation example Construction

[0070] The present invention also provides a method for preparing the stapler, characterized in that the stapler is melt-injected under the following conditions: the mold preheating temperature is 35-65°C, preferably 40-60°C, more preferably 45-55°C ℃; injection molding temperature is 215-235 ℃, preferably 220-230 ℃; injection pressure is 800-1200 bar, preferably 900-1100 bar; molding pressure is kept at 500-900 bar, preferably 650-800 bar; holding time is 2-8 seconds, preferably 3-6 seconds.

[0071] The gastrointestinal tract stapler provided by the invention has antibacterial, anti-inflammatory and hemostatic effects, and can be applied to drugs such as sulfonamides, quinolones, Anluoxue, and hemostasis. Drugs such as sulfonamides and quinolones have broad-spectrum antibacterial properties and can weaken or reduce postoperative inflammation of the gastrointestinal tract. Hemostatic drugs such as Anluoxue and Zhixuemin can reduce the permeability and fragility of capillarie...

preparation example 1

[0082] Preparation example 1, raw material preparation

[0083] Preparation of polyglycolide: Add 500 g of glycolide into the reactor, and add 0.005% (weight ratio) of stannous octoate catalyst into the reactor. The reaction system was sealed, and nitrogen gas was introduced to protect the reaction. The temperature of the reaction system was controlled at 120° C., and the reaction was carried out for 30 hours. The reactants were chopped to make pellets with a particle size of 1-8 mm, and 491 g of pellets were obtained by weighing, with a yield of 98.2%. The above pellets were dissolved in hexafluoroisopropanol solution, and the intrinsic viscosity of the polymer was measured as 3.28 dL / g by Ubbelohde viscometer in a constant temperature water bath at 25°C.

[0084] Preparation of raw materials for injection molding: 491 g of polyglycolide was packaged for use.

preparation example 2

[0085] Preparation example 2, raw material preparation

[0086] Preparation of polyglycolide: According to the method of preparation example 1, except that the reaction time was changed to 25 hours, 495 g of polyglycolide was prepared with a yield of 99%. According to the method of Preparation Example 1, the intrinsic viscosity of the polymer is 3.15 dL / g.

[0087] Preparation of injection molding raw materials: Mix 495g of polyglycolide and 26g of medical grade barium sulfate (ratio 95:5) evenly, and package for use.

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PUM

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Abstract

The invention provides an anastomat for gastrointestinal tract anastomosis surgery and a production method thereof. The anastomat comprises an anastomosis nail and a base and is divided into two types, namely a combined type and an independent type. The anastomat is composed of degradable materials and medical barium sulfate and can be finally disintegrated to be powder to be removed from the body after being used up. An envelope is formed on the outer surface of the anastomat through polyacrylic resin and contains medicines such as sulfonamides and quinolones antisepsis and anti-inflammation medicines and adrenobazonum, dicynone and other hemostasis medicines, and the envelope can selectively perform medicine slow release and controlled release according to different pH physiological environments of gastrointestinal tracts.

Description

technical field [0001] The invention relates to a medical instrument, in particular to a gastrointestinal tract stapler, which is mainly used in end-to-end anastomosis, end-to-side anastomosis and side-to-side anastomosis of human stomach, small intestine, large intestine and other digestive tracts. Background technique [0002] Surgical suturing is a commonly used surgical technique to reattach or reconstruct the channels of incised or traumatized tissues and organs, restore their functions, and ensure good healing. In 1881, Billroth successfully completed the first manual suture operation, and then the manual suture technique gradually matured, and suture became one of the important basic surgical techniques. Tissues and organs in different parts need to be sutured in different ways or methods. Simple suture is often used for suturing skin, subcutaneous tissue, muscle, and aponeurosis; eversion suture keeps the inner surface of the wound smooth, and is often used for sutur...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B17/115
Inventor 周秋梅郝峰张晓蕾张洁郑海菁裴明黎
Owner HANGZHOU MEDZONE BIO-TECH CO LTD
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