41 results about "Dermal collagen" patented technology

The present invention refers to a Laser therapy system and a method for skin treatment, comprising:

• • a unit for dispensing a Photosensitizer containing agent;
  • a first light source which generates at least one first light with a first wavelength;
  • a second light source as a Laser light source which generates at least a second light with a second wavelength;
  • an optical system which is connected to the first and to the second light source, comprising an electromechanical displacement device with an optical deflection and focusing system such that the first and second light gets focused and a respective focus point can be controllably positioned in the skin; and
  • a control unit for controlling the electromechanical displacement device and the first and the second light source such that the respective light spot with a controlled energy and position in the skin is produced.

A deep acting topically working facial care appliance includes a dual action facial puck having a rotating and counter rotatable facial implement that is dually effective both to clean, massage, apply compositions and otherwise topically work the skin and to deeply act to penetrate below the epidermis and into the dermis massaging and deeply passivating and enervating the dermis and dermal collagen.

An instrument and technique for the removal of epidermal layers in a controlled manner utilizing a hand-held instrument with a working end that (i) a vacuum aspiration system, (ii) a source for delivery of a sterile fluids or pharmacological agents to the skin; and (iii) a skin interface surface in the working end that has specially shape structure for abrading surface layers of the patient's epidermis as the working end is moved over the patient's skin while at the same time causing rapid penetration of the fluids into the skin for therapeutic purposes. Movement of the working end across the skin causes abrasion of the surface layers in a path over the patient's skin. The method of the invention may be used in a periodic treatment for the removal of superficial skin layers that enhances the synthesis of dermal collagen aggregates by inducing the body's natural wound healing response. The method of the invention creates more normal dermal architectures in skin with limited depths of skin removal by the series of superficial treatments that may be comparable to the extent of neocollagenesis caused by a deep skin removal treatment (e.g., CO² laser skin removal).

The invention discloses an oxidation chitosan graft modified porcine dermal collagen micro-nano fiber membrane and a preparation method thereof. The oxidation chitosan graft modified porcine dermal collagen micro-nano fiber membrane is characterized in that the preparation method comprises the steps: by applying an electrostatic spinning technology and using traceable purified porcine dermis as a raw material and hexafluoroisopropanol as a solvent, stirring at 4-10 DEG C until the mixture is transparent, formulating to obtain electrostatic spinning mother liquor with concentration of 0.5-10%, and directly spinning to obtain the porcine dermal collagen micro-nano fiber membrane; then performing graft modification on the porcine dermal collagen micro-nano fiber membrane by using oxidation chitosan, thereby finally obtaining the oxidation chitosan graft modified porcine dermal collagen micro-nano fiber membrane. A membrane material not only has good bio-compatibility, biodegradability and mechanical properties, but also has anti-oxidation effects, antibacterial activities, anti-inflammation/wound healing promotion effects, anti-cancer/anti-tumor effects and antiviral effects of chitosan, is significantly better than a collagen composite membrane material prepared by using collagen as the raw material, and can be widely applied to the preparation of biomedical materials such as hemostatic materials, tissue engineering scaffold materials, biological dressings and the like.

The invention discloses antigen-free porcine dermal collagen fibers and a preparation method thereof. The antigen-free porcine dermal collagen fibers with excellent performance and wide application are prepared by using purified porcine skin as a raw material and adopting a method of combining physics, chemistry and biochemistry to perform a series of treatment such as fluffing, fiber decomposition, fiber separation, carding and the like on the purified porcine skin on the premise of ensuring good mechanical property of the purified porcine skin unchangeable. The antigen-free porcine dermal collagen fibers have good biocompatibility, good mechanical property and proper degradability, and can be widely applied to preparation of medicinal biological materials such as tissue engineering scaffold materials, hemostatic materials, medicinal operation stitches and the like.

The invention discloses a preparation method of a xenogenic acellular dermal matrix. The method specifically includes the following steps of taking dermis, removing epidermal layers, conducting acellular disposal, punching holes through lasers, and conducting sterilizing. By means of the method, cell components are removed thoroughly, antigenicity is low, the dermal collagen structure is kept, histocompatibility is high, the time of the whole preparation process is only about 60 hours, disposal time is short, disposal cost is low, and good social benefits and economic benefits are achieved.

The invention relates to a preparation method of heterogeneous acellular dermal matrix. The preparation method comprises the following steps: taking bama miniature pig skin as a skin source, reversely taking split-thickness skin by adopting a skin drum, carrying out the steps of removing epidermis and extracting cells, thus obtaining acellular dermis, enabling the acellular dermis to react with carboxymethyl chitosan, thus obtaining acellular dermal matrix, finally, treating the acellular dermal matrix by adopting a softening agent and a humectant, so that the prepared acellular dermal matrix is closer to the natural state of the skin of the human body, and thus the use compliance of the acellular dermal matrix is improved. The heterogeneous acellular dermal matrix prepared by adopting the method disclosed by the invention is low in immunogenicity, meanwhile, the heterogeneous acellular dermal matrix keeps the three-dimensional stereoscopic structure of dermal collagen fibers, improves the stability of the three-dimensional structure of the dermal collagen fibers, and has the excellent biocompatibility.

The invention discloses a dermal collagen fiber prepared from tanning chromium-containing subsidiary waste and a preparation method thereof. In the preparation method, the tanning chromium-containing subsidiary waste is used as a raw material, is subjected to processing of puffing, separating fibers, splitting fibers and carding and the like by a physical, chemical and biochemical combination method on the premise of ensuring unchanged good physical and mechanical conditions of collagen fibers, and is prepared into the dermal collagen fiber with good performance and wide application ranges. The dermal collagen fiber reaches the following technical indexes: (1) the outer surface is provided with light blue fiber materials and does not have visible impurities; (2) the moisture content is between 18 and 25 percent; (3) the linear density is between 1.2 and 2.0 dtex; (4) the fiber length is between 20 and 30mm; (5) the breaking strength is more than or equal to 3.5 cN/tex; (6) the elongation at break is between 10 and 30 percent; and (7) the moisture regain is between 6 and 10 percent. The dermal collagen fiber can be used as raw materials of high-simulation leather (automobile seat leather, furniture leather, instep leather, garment leather, shoe lining leather, belt leather, luggage leather and the like), natural leather base cloth, senior carpets, senior wall paper, dermal fiber bedding and the like.

The present invention provides for the administration of aryl-substituted 1,1-diphosphonate compounds to increase the dermal collagen content of skin and effect improvement in photoaged skin, chronologically aged skin and in skin of postmenopusal women and patients suffering from osteoporosis.

The invention discloses a protein beverage formula for cosmetic whitening and a preparation method thereof. The protein beverage comprises the following raw materials in parts by weight: 100 parts ofwater, 5 to 10 parts of ocean fish oligopeptide powder, 6 to 12 parts of honey peach fruit powder, 8 to 15 parts of fructose-oligosaccharide, 5 to 10 parts of mulberry, 2 to 8 parts of soy peptide powder, 5 to 10 parts of acerola cherry powder, 2 to 5 parts of bird's-nest, 0.5 to 1 part of gamma-aminobutyric acid and 1 to 3 parts of vitamin C. The protein beverage disclosed by the invention has the advantages that excessive secretion of black poison is inhibited, deposited pigment and stains are metabolized, the skin metabolism is promoted, a dermal collagen network is repaired, and blood circulation of skin is promoted; the collagen supplementing structure is firmly fixed through elastin to form a tight and meticulous structure with filling and no collapse while collagen can be effectively supplemented for people; wrinkles are reduced and the elasticity is enhanced; the protein beverage is conductive to skin health and has a good beauty whitening effect.

The invention discloses a plant-derived polypeptide with an anti-aging effect, face cream containing the plant-derived polypeptide and a preparation method of the face cream. The plant-derived polypeptide is a sage seed polypeptide. Skin aging is a part of body aging, is shown as skin relaxation and thinning, and is one of the most intuitive external expressions of body aging due to wrinkle formation and gradual increase and deepening. Researches show that skin aging is related to the proliferation ability of skin fibroblasts and the decrease of the content of dermal collagen. Therefore, the promotion of the proliferation of human skin fibroblasts and the synthesis of collagen is an important aspect for keeping skin young and resisting aging. The test results show that the sage seed polypeptide can promote the proliferation of human skin fibroblasts and the synthesis of collagen by human skin fibroblasts, has an anti-skin aging effect, and can be used for preparing anti-skin aging cosmetics.

The invention discloses an environment-friendly building material and a preparation method thereof, and relates to the field of novel building materials. An intermediate layer of the environment-friendly building material is a collagen fiber net; an upper layer and a lower layer are woven fabric; a collagen fiber is extracted from wet blue leather waste. According to the preparation method of a collagen fiber thermal insulation material, the collagen fiber thermal insulation material with good service strength is prepared through simplifying and shortening extraction of the collagen fiber from the wet blue leather waste and a net-forming reinforcing process; the effects of using the collagen fiber in the blue wet leather waste and utilizing the collagen fiber in the blue wet leather waste at low cost on a large scale are reached; on one hand, the burden of the waste is relieved for leather-making enterprises, and a good method is provided for changing waste into treasures; on the other hand, a plurality of advantages that dermal collagen fibers are moisture-absorbing, breathable, lightweight, warm in winter and cool in summer, flame-retardant and the like are fully utilized, the building material is convenient to install on the spot, and is an environment-friendly building material; and an ideal choice is provided for pursuing environment-friendly and comfortable modern architecture.

The invention provides seabuckthorn oil body lotion containing hydrolyzed pearl powder flexible nano liposome. The seabuckthorn oil body lotion is prepared by conducting emulsification and homogenizing on the hydrolyzed pearl powder flexible nano liposome, seabuckthorn oil, emulgator, a moisturizing agent, stablizer and deionized water. Multiple nutrition substances including amino acid, microelements, polypeptide and the like contained in the hydrolyzed pearl powder are utilized, and metabolism of skin epithelial cells and dermal fibroblasts is effectively enhanced; the flexible nano liposome can penetrate through the skin surface of the human body easily to combine with cells, so that pearl powder plays a better functions, in cooperation with seabuckthorn oil which deeply moistens skin cutin to form cells and enhance the hydration of the dermal skin, the flexible nano liposome and the seabuckthorn oil jointly act, regeneration of a skin barrier and dermal collagen can be better promoted, skin texture is improved, health of the skin can be guaranteed, and skin resistance is enhanced. The seabuckthorn oil body lotion is natural, mild, nearly free of stimulation and capable of being used for moistening skin and preserving moisture for a long time, has good water supplementation and moisture preservation effects on dry skin, sensitive skin and the like and effectively whitens the skin.

The invention discloses a preparation method for a moisturizing cream for breast skin. The method comprises the steps that S1, liquid paraffin, stearic acid, IPP, acetylated lanolin, vaseline and monoglyceride are mixed to obtain an A mixture; S2, glycerol, gropylene glycol, konjac gum, (C16-C18) alkyl alcohol ethoxylate, methyl paraben, ethylenediaminetetraacetic acid disodium salt and water aremixed to obtain a B mixture; absolute alcohol, piperine, piperic acid, quercetin, ferulic acid and hyaluronic acid are fully mixed to obtain a C mixture. The moisturizing cream has the advantages of heat preserving, ultraviolet ray resisting and oxidation resisting, the skin elasticity can be improved, pigments can be reduced, wrinkles are lightened, ageing is slowed down, the skin is allowed to be tender and smooth, the absorption of other active components and nutritious substance can be promoted to improve the nutritious metabolism of skin, and a better environment is provided for the synthesis of dermal collagen and elastic fibers.

The invention discloses a composition as well as a preparation method and application thereof. The composition comprises a component (a), a component (b), a component (c) and a component (d), the component (a) is a soybean hydrolysate, the component (b) is a rambutan leaf extract, the component (c) is a kangaroo claw extract, and the component (d) contains a false leaf root extract and escin.

It is intended to provide a method whereby the skin conditions (for example, loss in the skin elasticity, wrinkle formation possibility, insufficient tightness in dermal collagen fiber bundles, or the like) can be exactly and conveniently assessed. It is also intended to provide a method whereby the wrinkle-improvement effect of a test substance can be exactly and conveniently evaluated. The skin conditions are assessed by using the expression amount of an adhesion factor in skin cells as an indication. The wrinkle reducing effect of a test substance is evaluated by using the expression amount of an adhesion factor in skin cells in the presence of the test substance as an indication.