20 results about "SKIN SCARRING" patented technology

The application relates to the technical field of biomedical materials, in particular to a wound paste for preventing skin scar formation and a preparation method thereof. The wound paste for preventing skin scar formation comprises an integrated composite film comprising an adhesion layer and a functional layer; the adhesion layer comprises first silk fibroin and metal ions; the metal ions have at least one of the effects of antibiosis, anti-inflammation and pro-angiogenesis; the functional layer comprises composite fibers with a core-shell structure; the core of the composite fiber comprises second silk fibroin and an angiogenesis inhibitor, and the shell comprises third silk fibroin. The wound paste is good in biocompatibility, convenient to apply, gradually releases effective components, adapts to the healing process of a wound, and is more scientific and effective in preventing scar formation.

The invention discloses a repair liquid matching method based on skin scar repair. The method comprises the following steps: S1, acquiring a skin type, a scar type, a scar area and scar depth information of a user; s2, establishing a repair liquid database for each factor of the skin of the user; s3, performing weighted calculation to obtain the scar with the highest repair priority in all scars of the skin of the user; and S4, selecting the repair liquid with the highest conformity as matching output. Weighted calculation is carried out on the skin type, the scar type, the scar area and the scar depth information of the user, and the scar with the highest repair priority in all scars of the skin of the user is obtained; according to the method, the factor with the highest repair priority, the previous treatment data and the same type of treatment data are used as factors to compare the repair liquid database, the repair liquid with the highest conformity is selected as matching output, a personalized scar repair scheme can be provided according to specific conditions of different patients, and therefore the scar repair effect is improved.

This invention relates to the field of medical image processing, specifically to a skin scar image segmentation method for automated skin scar region identification and quantitative analysis. It addresses the problems of low segmentation accuracy, inaccurate boundary modeling, and unreliable quantization calculations caused by insufficient feature representation, weak generalization ability, and reliance on manual intervention in existing methods. The method includes: S1 acquiring a skin scar image; S2 inputting a trained improved SAM2 segmentation network; and S3 outputting a segmentation mask. The improved SAM2 network is trained by constructing and preprocessing a dataset; it includes a frozen-parameter backbone image encoder, a cue encoder, a medical image feature guidance module (extracting texture details, color contrast, and edge morphology features), a residual enhancement module (fusing general features, cue vectors, and medical features through residual connections), and a mask decoder. During training, the backbone network parameters are frozen, and only the cue encoder, medical feature guidance module, residual enhancement module, and mask decoder are fine-tuned.

The invention belongs to the technical field of Chinese herbal medicine compositions, and discloses a traditional Chinese medicine ointment for preventing burn and scald skin scars and a preparation method thereof. The traditional Chinese medicine composition is prepared from the following components: 15 to 25 parts of cortex phellodendri, 12 to 18 parts of herba houttuyniae, 17 to 25 parts of ilex rotunda, 15 to 23 parts of carbonized sanguisorba root, 10 to 22 parts of purple grass, 8 to 15 parts of radix scutellariae, 5 to 8 parts of calomel, 8 to 19 parts of dragon liver, 10 to 12 parts of radix notoginseng, 6 to 8 parts of frankincense, 3 to 6 parts of borneol and 7 to 12 parts of bristle carbon powder. Mixing the raw materials, crushing and stirring together with the raw camellia oil, and sealing filtrate in a dark place; the traditional Chinese medicine ointment disclosed by the invention has the effects of quickly relieving pain, diminishing inflammation and preventing infection on burnt and scalded skin, and is capable of quickly promoting tissue regeneration without leaving scars. Active ingredients contained in the raw camellia oil have the effects of diminishing inflammation, sterilizing and repairing cells; in addition, the camellia oil can prevent effective components from being damaged due to overheating in a mechanical process during crushing of the Chinese herbal medicine components, and the active components are protected.

A method of enhancing the quality of a skin scar by topical application of an agent for improving scar quality is characterised in that said agent is pre-emptively applied to a potential surgical cutaneous site in advance of surgery, including surgery involving use of lasers. The topical agent may be a polyphenol, such as (-)-epigallocatechin-3-gallate (EGCG). Use of such a topical agent in advance of surgery leads to significant beneficial effects on dermal scarring by reducing mast cells, angiogenesis, skin thickness and simultaneously increasing elastin content. The topical agent may be applied directly or incorporated in a dressing, such as in a dermal patch comprising an adhesive silicone sheet, and can be worn both in the lead up to surgery and post-operatively.

The invention discloses an in-situ cross-linked silicone elastomer for scar repair and a preparation method thereof.The silicone elastomer is prepared by mixing a component A with vinyl polysiloxane and a moisture absorbent as main components and a component B with polyhydrosilane as a main component and then coating the surface of skin with the mixture, under the action of a catalyst, in-situ polymerization and crosslinking are carried out on the skin surface. The preparation method comprises the following steps: firstly, respectively preparing a component A containing vinyl polysiloxane, a moisture absorbent and the like and a component B containing polysilazane; respectively filling the component A and the component B into different containers, uniformly mixing by a static mixer according to a certain proportion, and uniformly smearing the mixture on a skin scar; and standing and curing at normal temperature to form the silicone elastomer at the skin scar. The adhesive provided by the invention has the advantages of good adhesive property, convenient coating property, hygroscopicity, moisture retention, stability, lowest skin irritation, good fitness and few residues.

The invention relates to siRNA of a targeted skin scar promoting gene and application of the siRNA, and belongs to the technical field of biology. The invention provides siRNA (small interfering Ribonucleic Acid) targeting a skin scar promoting gene, and an antisense strand of the siRNA can be specifically combined with the skin scar promoting gene so as to trigger the degradation of the skin scar promoting gene; the skin scar promoting gene is a gene for coding a transforming growth factor 1; a positive-sense strand of the siRNA comprises a nucleic acid molecule with a nucleotide sequence as shown in SEQ ID NO.1, and an antisense strand of the siRNA comprises a nucleic acid molecule with a nucleotide sequence as shown in SEQ ID NO.11. Researches show that the siRNA can target the skin scar promoting gene, is high in interference efficiency, has high inhibitory activity on the skin scar promoting gene, and provides a good theoretical and practical basis for skin scar treatment.

The application provides a quick positioning device for tension reduction scar surgery, relates to the technical field of tension reduction positioning for scar surgery, and is characterized in that the top end of the base is provided with a one-way opening groove, and the top end of the groove is provided with a cover plate for covering the top end opening of the base. The existing method is to adhere a component similar to a band-aid on the skin of a patient, and to realize the limiting operation on the scar through the limiting of the band-aid, but the size of the band-aid is inconvenient to adjust, and the precise positioning and tension reduction operation cannot be realized according to the size of the wound of the patient, so that the limitation problem exists. The mutual approaching between the two bases realizes the gathering and tension reduction operation on the skin scar of the patient, the design can automatically adjust the tension reduction operation on the scar according to the size and degree of the scar compared with the traditional tension reduction method, can be more beneficial to the healing work of the scar on the skin of the patient, and preferably improves the practicability of the device as a whole.

The application discloses application of a cytokine interleukin-17D (IL-17D) in preparation of a medicine for preventing and / or treating scars. IL-17D is highly expressed in fibroblasts, but is down-regulated in myofibroblasts in skin scars and keloids. Low expression of IL-17D makes IL-17D unable to inhibit expression of fibrosis-related genes, thus unable to inhibit differentiation of fibroblasts into myofibroblasts, thereby causing generation of scars. Overexpression of IL-17D or injection of recombinant IL-17D protein in a mouse full-thickness skin wound can significantly inhibit formation of scars; after IL-17D gene of the mouse is knocked out, expression of fibrosis-related genes in the skin wound is up-regulated, and scars after wound healing are obviously aggravated. Therefore, the application discloses that IL-17D can be used as a medicine for diagnosing and treating skin scars or keloids.

The present application relates to hollow guide bone fracture reduction device, including hollow sleeve (2, 3) and fracture reduction needle (1, 4), both are made of hard material;The front end of hollow sleeve (2, 3) is hollow sleeve (2), the rear end is provided with first handle (3), and the inside of first handle (3) and front section sleeve (2) is through type hollow structure;The front end of fracture reduction needle (1, 4) is single-side angle sharp solid rod (1), the rear end is provided with second handle (4), and is set in the inside of hollow sleeve (2, 3), when second handle (4) is twisted forward, the front end angle sharp part (11) is exposed outside hollow sleeve (2). When the percutaneous minimally invasive implant internal fixation is reduced, the method can achieve the effect that both clavicle fracture can be effectively and quickly reduced and skin scar can be reduced.

To provide a scar management product effective for reducing and / or preventing dermal scarring, and to provide a process of manufacture thereof.SOLUTION: Provided is a scar management product for reducing and / or preventing dermal scarring at a closed wound site, the scar management product comprises a skin-contacting layer having a skin-contacting surface, the skin-contacting layer having a first side and a second side, the first side of the skin-contacting layer comprising: the skin-contacting layer including the skin-contacting surface of the skin-contacting layer; and pirfenidone incorporated into the skin-contacting layer, and the skin-contacting layer being a cured silicone material having pirfenidone mixed therein.SELECTED DRAWING: Figure 1

The invention relates to the field of medical image processing, in particular to a skin scar image segmentation method which is used for automatic skin scar area recognition and quantitative analysis. The problems of low segmentation precision, inaccurate boundary modeling and unreliable quantitative calculation caused by insufficient feature expression, weak generalization ability and manual dependence in the existing method are solved. The method comprises the following steps: S1, acquiring a skin scar image; s2, inputting a trained improved SAM2 segmentation network; and S3, outputting the segmentation mask. The improved SAM2 network is obtained by constructing and preprocessing a data set; the system comprises a trunk image encoder for freezing parameters, a prompt encoder, a medical image feature guide module (extracting texture details, color contrast and edge morphological features), a residual enhancement module (fusing general features, prompt vectors and medical features through residual connection) and a mask decoder. During training, backbone network parameters are frozen, and only the prompt encoder, the medical feature guide module, the residual enhancement module and the mask decoder are finely adjusted.

This invention discloses a bioactive composite gel dressing for skin scar repair that inhibits lactic acid production, belonging to the technical field of scar repair gel dressings. The gel dressing is obtained by mixing methacrylamide-modified hyaluronic acid, methacrylamide-modified carboxymethyl chitosan, and mesoporous polydopamine, followed by a cross-linking reaction initiated by a cross-linking monomer and a photoinitiator. The mesoporous polydopamine is loaded with berberine and resveratrol. The cross-linking monomer can gradually degrade in the weakly acidic, highly reactive oxygen species microenvironment of scars, achieving controlled release of active substances. The mesoporous polydopamine combines drug carrier and antioxidant functions; its three-dimensional porous network structure contains numerous carboxyl groups, providing a moist environment for the wound. The long-chain alkane structure of the cross-linking monomer enhances the compatibility and transdermal properties of hydrophobic drugs. The active substances berberine and resveratrol inhibit lactic acid production and abnormal fibroblast proliferation. This dressing has high biocompatibility, and its decomposition products can participate in skin protein synthesis and barrier repair.

The invention relates to the technical field of medical and industrial cross, and discloses an intelligent tension reducing device for improving skin scars and a sequential dynamic tension reducing method thereof.The device comprises a first auxiliary pasting film, a second auxiliary pasting film and a negative feedback sequential dynamic tension adjusting device; the two ends of the negative feedback time sequence dynamic adjusting tension device are fixed to the first auxiliary pasting film and the second auxiliary pasting film respectively, and the first auxiliary pasting film and the second auxiliary pasting film are pasted to the two sides of a human skin wound. The negative feedback time sequence dynamic tension adjusting device comprises a tensioning curved block, a tension adjusting module and a tension detection and negative feedback module; the two ends of the tensioning curved block are fixed to the first auxiliary pasting film and the second auxiliary pasting film respectively. The tension adjusting module is arranged on the tensioning curved block; and the tension detection and negative feedback module is arranged on the tensioning curved block. The technical problems that an existing skin tension reducing device is seriously intervened in an empirical mode, and real-time dynamic tension reducing management on the time domain is difficult to meet are solved.

The invention discloses a bioactive composite gel dressing for skin scar repair and capable of inhibiting generation of lactic acid, and belongs to the technical field of scar repair gel dressings. The gel dressing is obtained by mixing methacrylamidated hyaluronic acid, methacrylamidated carboxymethyl chitosan and mesoporous polydopamine and then initiating a cross-linking reaction through a cross-linking monomer and a photoinitiator, and berberine and resveratrol are loaded on the mesoporous polydopamine. The cross-linking monomer can be gradually degraded in a micro-environment with weak acidity and high active oxygen of scars, so that the controllable release of active substances is realized; mesoporous polydopamine has the functions of a drug carrier and antioxidation, a three-dimensional porous network structure contains more carboxyl groups and can provide a moist environment for a wound surface, and a long-chain alkane structure of a cross-linking monomer can enhance the compatibility and transdermal performance of a hydrophobic drug. The active substances berberine and resveratrol can inhibit the generation of lactic acid and inhibit the abnormal proliferation of fibroblasts. The dressing is high in biocompatibility, and decomposition products can participate in skin protein synthesis and barrier repair.

The invention relates to the technical field of terahertz irradiation systems, in particular to a terahertz irradiation system for skin scar repair. According to the technical scheme, the device comprises a terahertz wave generation module, a transmitting antenna, a control module and a power supply module, wherein the terahertz wave generation module is used for generating continuous terahertz waves with the frequency within the range of 60-200GHz and the output power smaller than 1W; the transmitting antenna is connected with the terahertz wave generating module and used for guiding and irradiating the terahertz waves to a skin scar area. According to the terahertz irradiation system provided by the invention, low-energy terahertz waves are used for skin corium layers in an uncreated manner, and the dual advantages of being painless, safe and accurate in repair are achieved; the built-in intelligent control system can adjust the power and the distance in real time, so that scalding is effectively prevented, and the operation safety is guaranteed; meanwhile, the system has the advantages of being portable, easy to use and controllable in cost, the daily nursing requirements of families can be met, and efficient and comfortable non-invasive scar repair is achieved.

The utility model relates to an update of a lock catch structure of a skin scar tension reducing device. On the basis of the previous invention, the anti-slip structure of the lock catch part of the skin scar tension reducing device is provided, and the four limbs and the trunk of the anti-slip structure can move freely and cannot slip off. The structure is characterized in that the clamp-shaped lock catch comprises a bottom plate fixed on the lock catch attachment part, an inclined plate in acute angle connection with the bottom plate, a front baffle in acute angle connection with the inclined plate and a rear baffle in acute angle connection with the bottom plate, and the bottom plate is fixedly connected with the inclined plate, the inclined plate is fixedly connected with the front baffle, and the bottom plate and the rear baffle are fixedly connected.

1. Name of the product in this design: Scar Removal Device (Medical Aesthetics Department). 2. Purpose of this design: This design is used for medical cosmetic skin scar repair. 3. The key design feature of this product is its shape. 4. The image or photograph that best illustrates the design's key points: a 3D model.

This invention relates to the fields of medical device manufacturing, radionuclide therapy, and automated control technology, specifically to an automated dressing manufacturing method and equipment, comprising: acquiring a skin scar image; segmenting and generating a target area feature map using an image recognition model; generating a cutting path based on the image and automatically cutting a carrier material to form a substrate matching the shape of the scar; quantitatively applying phosphorus-32 solution to the substrate according to preset activity parameters; and post-processing to produce a phosphorus-32 dressing. This invention accurately reproduces the scar contour through image recognition and automatic cutting, achieving a high degree of morphological matching and improving irradiation accuracy; parameterized application ensures uniform dosage, improving treatment safety and efficacy stability; and the fully automated process shortens the preparation cycle, reduces manual intervention, efficiently meets clinical needs, and simultaneously reduces the risk of radioactive operation, enhancing radiation safety.

The invention discloses an intelligent dynamic directional assembly-disassembly soft tissue repair material as well as preparation and application thereof, and belongs to the technical field of intelligent soft tissue repair materials. By selecting proper target materials and using different modification methods and special preparation modes for different forms of target materials, the target materials have oriented high-oxidation-state structures or highly-uniform high-oxidation-state structures, amine compounds are selectively subjected to long-wave response function modification, and through pH change and long-wave stimulation, the long-wave response function of the amine compounds is improved. And regionalized directional dynamic assembly-disassembly of the composite material is realized. The repair material has the advantages of multiple forms, multi-occasion adaptability, simplicity and convenience in operation, good biocompatibility, proper viscosity and injectability, proper mechanical property and degradability, excellent tissue repair performance and the like, and is used for repairing various soft tissues; the method includes repairing endometrium, vagina, abdominal cavity endometrium, cartilage, skin superficial trauma, digestive tract, stomach wall, urethra and the like and eliminating skin scars.