The invention relates to biological whitening and moisturizing cream. The biological whitening and moisturizing cream comprises four parts, namely biological juice, a biological extracting solution, biological essential oil and glycerin, wherein the biological juice comprises aloe vera juice and cucumber juice; the biological extracting solution comprises a radix rehmanniae extracting solution, a licorice extracting solution and a grape seed extracting solution; and the biological essential oil comprises neroli essential oil, rose essential oil, olive oil and almond oil. The mass parts of various materials are as follows: 15-35 parts of aloe vera juice, 20-40 parts of cucumber juice, 10-15 parts of radix rehmanniae extracting solution, 10-15 parts of licorice extracting solution, 15-30 parts of grape seed extracting solution, 10-25 parts of neroli essential oil, 10-25 parts of rose essential oil, 10-25 parts of olive oil, 10-15 parts of almond oil, and 10-20 parts of glycerin. The biological whitening and moisturizing cream provided by the invention is suitable for being used in the morning and evening, preferably used before going to bed late in the evening, and uniformly applied on the face, can be used as a primer when being used in the morning, and is applicable to all types of skin for a long time. The biological whitening and moisturizing cream provided by the invention is harmless to a human body, does not have side effects, and is good in whitening and moisturizing effects; the biological whitening and moisturizing cream can inhibit the growth of melanin, and is good in spot solution effect; and the biological whitening and moisturizing cream can keep the luster and elasticity of the skin, and is nourishing and anti-wrinkle, and good in delicateness restoring effect.