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Hyaluronic acid mouth care film and preparation method and application thereof

A technology of hyaluronic acid and oral care, which is applied in the direction of pharmaceutical formulas, medical preparations containing active ingredients, and the digestive system, which can solve the problems of single function and unfavorable promotion, and achieve high safety, improve the safety of use, and improve dental health. The effect of reducing allergies

Active Publication Date: 2016-12-07
BLOOMAGE BIOTECHNOLOGY CORP LTD +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0010] In order to solve the problem of single function and unfavorable promotion of hyaluronic acid products in oral health care in the prior art, this application provides a hyaluronic acid oral care film with the functions of inhibiting bacteria and repairing cell damage.

Method used

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  • Hyaluronic acid mouth care film and preparation method and application thereof
  • Hyaluronic acid mouth care film and preparation method and application thereof
  • Hyaluronic acid mouth care film and preparation method and application thereof

Examples

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Embodiment Construction

[0037] The present invention will be further described below in conjunction with specific embodiment:

[0038] 1. The composition of embodiment formula

[0039]

[0040] Note: The values ​​in the table are the weight percentages of each component in the dry film.

[0041] 2. the preparation technology of embodiment:

[0042]Each embodiment prepares 100g solution respectively. First add sodium hyaluronate and (or) zinc hyaluronate, and hydrolyzed sodium hyaluronate into a corresponding amount of water, heat to 60-65°C under stirring, and continue stirring to fully dissolve. Then, add the rest of the ingredients, stir to dissolve and mix evenly, then spread it on a stainless steel plate with a thickness of 0.3mm, and dry it at 45-50°C to form a film (the residual moisture in the dry film is controlled to be 9%).

[0043] 3. Membrane Mechanical Properties Test

[0044] Method: Use a universal material testing machine to perform a tensile test on the samples of each example...

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Abstract

The invention relates to the technical field of hyaluronic acid products, in particular to a hyaluronic acid mouth care film. The dry film contains the following components in percentages by weight: 10% to 50% of sodium hyaluronate, 10% to 40% of zinc hyaluronate and 10% to 40% of hydrolytic sodium hyaluronate. Hyaluronic acid and derivatives thereof are taken as film-forming materials of the mouth film, so that the mechanical property of the film is obviously improved, and the flexibility is strengthened; the hyaluronic acid and derivatives thereof are taken as main active ingredients of the mouth film and have various biological activities, and the hyaluronic acid has the effects of relieving release, promoting absorption and synergistically interacting for other added active ingredients; besides the biological activities of sodium hyaluronate, the zinc hyaluronate has higher anti-bacteria and anti-inflammation effects, and is more beneficial to mouth health, mouth disease prevention and treatment and throat nursing; the product disclosed by the invention is light in weight, small in size and convenient to carry and transport.

Description

technical field [0001] The invention relates to the technical field of hyaluronic acid products, in particular to a hyaluronic acid oral care film, and also relates to a preparation method and application of the hyaluronic acid oral care film. Background technique [0002] Oral film is a film-like preparation prepared by processing drugs and suitable film-forming materials for oral or mucosal use. It is usually composed of water-soluble film-forming materials, plasticizers, disintegrants, fillers, flavoring agents, drugs, etc. Film-forming materials are the largest proportion of excipients in instant film formulations, accounting for more than 45% of the dry weight of film formulations, among which hypromellose, pullulan and gelatin are the most commonly used film-forming materials. Other commonly used film-forming materials include polycarbophil, cellulose derivatives, pullulan, xanthan gum, sodium alginate, chitosan, polyethylene oxide, polyvinyl alcohol, etc. Different ...

Claims

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Application Information

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IPC IPC(8): A61K9/70A61K31/728A61P1/02A61P11/04A61P31/02
Inventor 黄思玲张晓鸥阚洪玲王海英王玉玲郭学平刘爱华
Owner BLOOMAGE BIOTECHNOLOGY CORP LTD
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