31 results about "Zinc hyaluronate" patented technology

The invention discloses a dressing composition used for inhibiting scars and accelerating wound healing and application thereof. The dressing composition consists of chitosan, acidic polysaccharide and panax notoginseng saponins in a weight proportion of 100:10-50:10-100, wherein the chitosan is selected from chitosan, chitosan lactate, acetate and hydrochloride; the acidic polysaccharide is selected from sodium carboxymethyl chitosan, sodium hyaluronate, zinc hyaluronate, sodium alginate and sodium carboxymethyl cellulose; and the panax notoginseng saponins accounts for no less than 40.0 percent of the total weight of ginsenosides Rg1 and Rb1. The formulations of the dressing composition are xerogel powder, capsules, gel membranes, hydrogels and fiber coatings. The dressing composition is used for wounds, burns, scalds, crush injuries, skin ulcers, gastroenteric ulcers and no healing of the wounds, has the advantages of rapid hemostasis, exudate reduction, moisturizing, air permeability, bacteriostasis, inflammation diminishing, itch relieving, no adhesion, effective inhibition of scarring, remarkable reduction of wound healing time and no need of replacing dressings, so that thedressing composition basically meets requirements of perfect functional external dressings.

The invention relates to the technical field of hyaluronic acid products, in particular to a hyaluronic acid mouth care film. The dry film contains the following components in percentages by weight: 10% to 50% of sodium hyaluronate, 10% to 40% of zinc hyaluronate and 10% to 40% of hydrolytic sodium hyaluronate. Hyaluronic acid and derivatives thereof are taken as film-forming materials of the mouth film, so that the mechanical property of the film is obviously improved, and the flexibility is strengthened; the hyaluronic acid and derivatives thereof are taken as main active ingredients of the mouth film and have various biological activities, and the hyaluronic acid has the effects of relieving release, promoting absorption and synergistically interacting for other added active ingredients; besides the biological activities of sodium hyaluronate, the zinc hyaluronate has higher anti-bacteria and anti-inflammation effects, and is more beneficial to mouth health, mouth disease prevention and treatment and throat nursing; the product disclosed by the invention is light in weight, small in size and convenient to carry and transport.

The invention relates to pharmaceutical compositions against peptic ulcer as well as to a method of treating peptic ulcer. The compositions contain and the method of treatment employs zinc hyaluronate as an active ingredient having a molecular weight in the range of 500,000 to 1,200,000 daltons.

A process for preparing the zinc hyaluronate features the ionic exchange between sodium hyaluronate and Zn salt in alcohol solution.

The invention discloses a preservative-free skincare mask essence. The formula of the mask essence contains no preservatives or other sensitizing substances, so the mask essence reduces the irritation of a mask to skins, and is suitable for sensitive skins. All ingredients in the formula do not degenerate or change the physical state after existing at 115 DEG C for 15-30 min; the addition of zinchyaluronate makes the mask essence have anti-inflammatory and moisturizing effects; and the molecular weights of the sodium hyaluronate have three types which are a large type, a medium type and a small type, and a ratio among the three types of molecular weights is controlled to achieve a best moisturizing effect.

The present application discloses a preparation method for an ophthalmic composition. The method includes the following steps: dissolving a high-molecular-weight hyaluronate and a low-molecular-weighthyaluronate in water under heating conditions, adding sodium chloride, performing uniform stirring, adjusting the pH to be alkaline by using an inorganic alkali or salt, performing alcohol precipitation, performing washing, and performing drying to obtain compound hyaluronate powder; dissolving the compound hyaluronate powder in water, and adding zinc hyaluronate, tetrahydropyrimidine or a tetrahydropyrimidine derivative to obtain a mixed solution; and adjusting the pH of the mixed solution, and performing filter sterilization or heat press sterilization to obtain the ophthalmic composition.The present application also provides the ophthalmic composition. The ophthalmic composition provided in the present application contains the compounded sodium hyaluronate, the zinc hyaluronate and the tetrahydropyrimidine, does not contain preservatives, the sodium hyaluronate, the zinc hyaluronate and the tetrahydropyrimidine have synergistic effects, and the composition has the effects of reducing tear evaporation, protecting ocular surface cells, stabilizing tear films, and relieving visual fatigue.

The invention discloses a hyaluronic acid-containing vola repairing and moisturizing spray and a preparation method thereof. The hyaluronic acid-containing vola repairing and moisturizing spray is prepared from super-active sodium hyaluronate, medium and low molecular weight sodium hyaluronate, zinc hyaluronate, low molecular weight zinc hyaluronate, centella asiatica extract, vitamins, amino acids, a preservative and purified water. The preparation method of the spray comprises the following steps: weighing the components, dissolving, filtering and filling into a spray bottle to prepare the water-soluble spray. The spray can be used for foot chapped symptoms commonly existing in life, and has the effects of foot moisturizing, bacteriostasis, inflammation diminishing and repairing. Super-active sodium hyaluronate, medium and low molecular weight sodium hyaluronate, zinc hyaluronate, low molecular weight zinc hyaluronate and centella asiatica are combined according to a certain mass ratio and can interact with one another, so that a synergistic effect is achieved, and the antibacterial and anti-inflammatory effects of the hyaluronic acid-containing vola repairing and moisturizing spray are remarkably improved.

The invention provides a structure dressing with compounding of oxidized graphene and nanofiber and a preparation method. The preparation method comprises the following steps: firstly mixing and stirring nano titanium dioxide, zeolite and PVA (Polyvinyl Alcohol) solution to be uniform so as to form slurry, and coating on the surface of a supporting layer; before drying, spraying a layer of 0.2-2%sodium alginate solution, and drying at a temperature of 40-75 DEG C to form a thin layer; then covering a layer of nanofiber on the surface of the thin layer, then coating slurry prepared from the oxidized graphene, the sodium alginate, zinc hyaluronate, vitamin B2 and vitamin B12, drying, and spraying a little amount of zinc salt solution to cure. The structure dressing provided by the inventionhas the beneficial effects that on the basis of the physical sterilization mechanism of the graphene and by combination with the breathable blocking action of a nanofiber film, the structure dressingis prepared by loading effective components; by adsorption and disinfection of all layers to tissue transudate, the aseptic condition of wounds is kept, and necessary nutritional substances are provided, so that secondary infection of the wounds is avoided, the heeling is enhanced and the preparation method is simple.

The invention relates to the technical field of injection reagent, in particular to a submucosal injection solution composition for an endoscope and a preparation method. The composition is prepared from 0.01 w/v% to 0.5 w/v% of hyaluronic acid, 0.005 w/v% to 0.5 w/v% of carboxymethyl chitosan, 0.001 w/v% to 0.1 w/v% of coloring agent and the balance of phosphate buffer solution, wherein the hyaluronic acid is selected from sodium hyaluronate, magnesium hyaluronate, calcium hyaluronate or zinc hyaluronate; the substitution degree of the carboxymethyl chitosan is greater than 0.85, and the dynamic viscosity of the carboxymethyl chitosan is 500-5000 mPa*s; and the coloring agent is selected from trypan blue, methylene blue, indigo blue, gentian violet or indocyanine green. The hyaluronic acid, the carboxymethyl chitosan and the coloring agent are combined for use, relatively long mucous membrane lifting time is kept, the lesion boundary is clearly displayed, postoperative bleeding and infection are reduced, and the submucosal injection solution can serve as an endoscopic submucosal injection solution to be applied to endoscopic surgery.

The invention discloses a zinc hyaluronate-containing private care packing suppository and a preparation method thereof. The zinc hyaluronate-containing private care packing suppository contains zinchyaluronate, carbohydrates, lactic acid, glycerin, gelatin and water. The private care packing suppository is used for female private part care, a layer of film can be formed on the inner surface of the vagina, harmful bacteria are inhibited, nutrient substances are provided for beneficial bacteria in the vagina, and therefore the effects of resisting bacteria, diminishing inflammation, lubricating, preserving moisture and promoting lactobacillus to become dominant strains are achieved.

The invention provides a preparation method of high-molecular-weight zinc hyaluronate, comprising the following steps of: adding sodium hyaluronate into a replacement solution, and replacing to obtainzinc hyaluronate precipitate; washing the precipitate with a washing liquid; and dehydrating the washed precipitate with a dehydration solution, and carrying out vacuum drying to obtain the high-molecular-weight zinc hyaluronate powder. According to the preparation method, the optimal preparation conditions are obtained by exploring the preparation conditions such as the replacement liquid pH, the replacement frequency, the washing pH, the washing frequency, the dehydration liquid pH and the dehydration frequency. The molecular weight of the zinc hyaluronate prepared by the preparation methoddisclosed by the invention can reach 1,000,000 Da or above, the light transmittance is greater than 99.5 percent, the zinc content is greater than 7.0 percent, and the problems of low molecular weight and low clarity are successfully solved.

The invention discloses hyaluronic acid oral liquid as well as a preparation method and application thereof. The hyaluronic acid oral liquid comprises the following components: 0.61 to 1.36 percent of hyaluronate; 0.3% to 0.9% of collagen peptide; 1.6%-3.1% of vitamin C and/or vitamin E; 0.2%-1.2% of a grape seed extract; 0.01% to 0.08% of isoflavone; 0.05% to 0.06% of nicotinamide; 0.02% to 0.04% of potassium sorbate; and the balance of water. The molecular weight of the hyaluronate is 10kDa-70kDa, the pH value of the hyaluronate is 6.5-7.0, and the hyaluronate comprises sodium hyaluronate and/or zinc hyaluronate. The hyaluronic acid oral liquid disclosed by the invention has efficient absorption capacity, is more easily absorbed by a human body, can be used for protecting the skin of the human body (especially moisturizing), achieves the protection of the skin of the whole body, and can fundamentally solve the protection problem of the skin.

The invention discloses an antibacterial release paper and a production method thereof. The antibacterial release paper comprises a base paper layer, a pre-coated layer and an isolation layer; the pre-coated layer comprises, by weight, 8-13 parts of lipoic acid, 6-15 parts of zinc hyaluronate, 4-8 parts of chitosan, 8-15 parts of seaweed gel, 5-10 parts of sodium lignosulfonate and 5-10 parts of butyl acetate; and the isolation layer comprises, by weight, 10-15 parts of an aqueous polyvinyl alcohol solution, 7-10 parts of benzotriazole, 5-8 parts of ferric citrate, 4-6 parts of polyoxyethylenecastor oil and 5-8 parts of disodium hydrogen phosphate. The antibacterial release paper is produced by compounding the base paper layer, the pre-coated layer and the isolation layer, and has the characteristics of good antibacterial effect and high strength, and the antibacterial rate of the antibacterial release paper on Escherichia coli and Staphylococcus aureus is 99% or more; and the production method has the advantages of easily available raw materials, easiness in realizing production process conditions, low production cost, and facilitation of production.

The invention relates to the field of cosmetics, and discloses preparation of an anti-acne hydrolat toner (toning lotion). The characteristics of the preparation are that anti-acne hydrolat, zinc hyaluronate, salicylic acid and derivatives, quaternium-73, hexamidine diisethionate, vitamin B6, vitamin B12, lactic acid and cosmetic auxiliary functional substances are taken to prepare the solvent-based cosmetic toner (toning lotion). The product has the efficacy of removing acne, and can meet the demands of people for daily skin care.