31 results about "Zinc hyaluronate" patented technology

A process for preparing the zinc hyaluronate features the ionic exchange between sodium hyaluronate and Zn salt in alcohol solution.

The invention discloses a dressing composition used for inhibiting scars and accelerating wound healing and application thereof. The dressing composition consists of chitosan, acidic polysaccharide and panax notoginseng saponins in a weight proportion of 100:10-50:10-100, wherein the chitosan is selected from chitosan, chitosan lactate, acetate and hydrochloride; the acidic polysaccharide is selected from sodium carboxymethyl chitosan, sodium hyaluronate, zinc hyaluronate, sodium alginate and sodium carboxymethyl cellulose; and the panax notoginseng saponins accounts for no less than 40.0 percent of the total weight of ginsenosides Rg1 and Rb1. The formulations of the dressing composition are xerogel powder, capsules, gel membranes, hydrogels and fiber coatings. The dressing composition is used for wounds, burns, scalds, crush injuries, skin ulcers, gastroenteric ulcers and no healing of the wounds, has the advantages of rapid hemostasis, exudate reduction, moisturizing, air permeability, bacteriostasis, inflammation diminishing, itch relieving, no adhesion, effective inhibition of scarring, remarkable reduction of wound healing time and no need of replacing dressings, so that thedressing composition basically meets requirements of perfect functional external dressings.

The invention relates to pharmaceutical compositions against peptic ulcer as well as to a method of treating peptic ulcer. The compositions contain and the method of treatment employs zinc hyaluronate as an active ingredient having a molecular weight in the range of 500,000 to 1,200,000 daltons.

The invention relates to pharmaceutical compositions with activity against disorders of urogenital system of mammals which comprises a zinc-hyaluronan complex as active ingredient and a pharmaceutically acceptable carrier and / or additive. The process for the preparation of said pharmaceutical compositions as well as the therapeutic use thereof for the treatment and prevention of diseases associated with abnormalities and deficiencies of glucosaminoglycan (GAG) layer in the urogenital system in mammals and a kit comprising zinc hyaluronate solution, a catheter which is applicable to intravesical administration and optionally a balloon which is applicable to bladder dillatation are also within the scope of the invention.

The present invention relates to a wound repairing spray and its preparation method and application. The wound repairing spray comprises the following components: 10-20wt% bioactive glass, 5-10wt% zinc hyaluronate, 50-70wt% solvent, 5-15wt% propellant, 0.1-0.5wt% film-forming agent and 1-5wt% penetration enhancer, the solvent is 70wt% ethanol aqueous solution of pH 6-7, the weight of the bioactive glass and zinc hyaluronate ratio of 2:1, the bioactive glass consists of Na 2 O, CaO, P 2 o 5 and SiO 2 composition, the particle size is 40-60 μm, and the molecular weight of the zinc hyaluronate is 10-15kDa. The wound repair spray can greatly enhance the role of bioactive glass in promoting wound healing and wound repair, and is convenient to use, has good stability and low irritation, and is especially suitable for treating diabetic ulcers, diabetic feet, bedsores, sinuses or Soft tissue ulcers or long-term erosions such as fat liquefaction wounds.

The present application discloses a preparation method of an ophthalmic composition, comprising the following steps: dissolving high-molecular-weight hyaluronate and low-molecular-weight hyaluronate in water under heating conditions, adding sodium chloride and stirring evenly, and using inorganic alkali or salt to adjust the pH to alkaline, and obtain compound hyaluronate powder through alcohol precipitation, washing and drying; dissolve the compound hyaluronate powder in water, and then add zinc hyaluronate, ectoine or hydropyrimidine derivatives to obtain a mixed solution; adjusting the pH of the mixed solution, and filtering or autoclaving to obtain an ophthalmic composition. The present application also provides an ophthalmic composition. The ophthalmic composition provided by the present application, the composition contains compounded sodium hyaluronate, zinc hyaluronate and ectoine, does not contain preservatives, and the sodium hyaluronate, zinc hyaluronate and ectoine act synergistically , has the effects of reducing tear evaporation, protecting ocular surface cells, stabilizing tear film, and relieving visual fatigue.

The invention relates to the technical field of hyaluronic acid products, in particular to a hyaluronic acid mouth care film. The dry film contains the following components in percentages by weight: 10% to 50% of sodium hyaluronate, 10% to 40% of zinc hyaluronate and 10% to 40% of hydrolytic sodium hyaluronate. Hyaluronic acid and derivatives thereof are taken as film-forming materials of the mouth film, so that the mechanical property of the film is obviously improved, and the flexibility is strengthened; the hyaluronic acid and derivatives thereof are taken as main active ingredients of the mouth film and have various biological activities, and the hyaluronic acid has the effects of relieving release, promoting absorption and synergistically interacting for other added active ingredients; besides the biological activities of sodium hyaluronate, the zinc hyaluronate has higher anti-bacteria and anti-inflammation effects, and is more beneficial to mouth health, mouth disease prevention and treatment and throat nursing; the product disclosed by the invention is light in weight, small in size and convenient to carry and transport.

The invention provides a preparation method of high-molecular-weight zinc hyaluronate, comprising the following steps: adding sodium hyaluronate into a replacement solution for replacement to obtain a zinc hyaluronate precipitate; washing the precipitate with a washing solution; The subsequent precipitation is dehydrated with a dehydrating solution, and vacuum-dried to obtain high molecular weight zinc hyaluronate powder. The preparation method of the present invention obtains the best preparation conditions by exploring the preparation conditions such as replacement liquid pH, replacement times, washing pH, washing times, dehydration liquid pH, and dehydration times. The zinc hyaluronate obtained by the preparation method of the invention has a molecular weight of more than 1 million Da, a light transmittance of more than 99.5%, and a zinc content of more than 7.0%, successfully solving the problems of low molecular weight and low clarity.

The invention relates to a shampoo composition containing zinc hyaluronate. In addition to water, the shampoo contains: (A) 1% to 30% by weight of the composition containing zinc hyaluronate anti-dandruff actives; (B) 5.0% to 40% by weight of the composition anionic surfactant; (C) 1.0% to 10% by weight of the composition cocamidopropyl betaine; (D) 0.05% to 3.0% by weight of the composition cationic polymer. The shampoo composition of the present invention contains active ingredients derived from nature and fermentation, and achieves good effects of scalp nourishment, oil control and anti-dandruff through the superposition of scalp moisturizing, antibacterial, soothing, oil-controlling and anti-itching effects, thereby maintaining scalp and dandruff. The healthy state of the hair, dandruff is not dry.