182results about How to "Short onset time" patented technology

The present invention relates to a pure natural beverage with the function of relieving alcoholism. It is made of 23 Chinese medicinal materials of pueraria root, oyster shell, poria, Chinese yam, crataegus fruit, lablab bean, lily bulb and others through a special preparation process. It can quickly obtain obvious effect of relieving alcoholism and possesses the function of protecting liver.

The invention discloses an external skin care product capable of adjusting skin immunity and delaying skin aging. The external skin care product is characterized by comprising powder, an aqueous solution and emulsion, wherein the powder comprises oligopeptide-1 and ginsenoside; the aqueous solution comprises glycyrrhiza glabra root extract, artemisia capillaris flower extract, mulberry root extract, jujube fruit extract, scutellaria root extract, hydrolyzed rice protein and nicotinamide; and the emulsion comprises hgytantriol bifida ferment lysate, creatine, carnosine, alpha glucosyl hesperidin, hexapeptide-3, centella asiatica extract, coenzyme Q10 inclusion complex, opuntia ficus-indica stem extract, rhodiola rosea extract, saussurea involucrate extract, pseudo-ginseng root extract and Chinese angelica extract inclusion complex. According to the external skin care product, the powder, the aqueous solution and the emulsion are jointly used, and the external skin care product can reduce wrinkle and pachulosis, even skin tone and improve skin elasticity and skin firmness, so that the skin is finer and smoother and looks young.

The present invention relates to the R-isomers of anesthetic compounds, the methods of treatment therewith, the compounds being useful for inducing local anesthesia, analgesia and sleep.

Terpene-enriched cannabinoid composition. Cannabinoid compositions are described including at least one cannabinoid in a specific amount, a primary terpene in a specific amount, at least 5% by weight of a non-cannabinoid, non-terpene, carrier, optionally at least three secondary terpenes; less than 5% by weight glycol; and less than 20% by weight water, where said non-cannabinoid, non-terpene carrier comprises cellulose and the terpenes to cannabinoids weight / weight ratio in said composition is about 0.1 to about 1.0. Also described are the above compositions where said non-cannabinoid, non-terpene carrier comprise less than 5% by weight cellulose and the terpenes to cannabinoids weight / weight ratio in said compositions is about 0.05 to about 1.0, forming terpene-enriched cannabinoid compositions with enhanced therapeutic effect compared with that of a composition comprising the same cannabinoids amounts and one half the amount of said primary terpene.

The invention relates to long-acting combination type wound dressing and a preparation method thereof. The long-acting combination type wound dressing comprises chitosan, oligo-chitosan, chitosan oligosaccharide, glacial acetic acid, isinglass, glycerol and purified water, wherein 100 milliliters of purified water contains 0.5g-8g of isinglass, 0.5g-10g of oligo-chitosan, 0.5g-10g of chitosan oligosaccharide, 0.3g-6g of isinglass, 0.3 milliliters-6 milliliters of glacial acetic acid and 1 milliliters-10 milliliters of glycerol. The long-acting combination type wound dressing is novel bio-hydrogel dressing which is short in onset time and is long in action time, can promote the healing of burn and scald wounds and acute and chronic wounds, and has three functions of hemostasis, analgesia and healing promotion; three main raw materials with different molecular weight gradients, such as chitosan, oligo-chitosan and chitosan oligosaccharide, are used, so as to achieve the purpose that the main raw materials are gradually absorbed in turn and exerts actions.

The invention relates to a triad integration freckle-removing functional nano cream for skin external use and a method for preparing the same. The three types (night use type, daytime use type and auxiliary type) freckle-removing nano creams improve and optimize a novel international passive target transdermal drug delivery system (TDDS) as a carrier, and organically combine and solubilize freckle-removing functional components with different biological efficacies, action ways and physical and chemical properties to form a good mutual aid synergic function system which has remarkable effect of controlling and relieving colored patches (such as chloasma, inflammatory pigmentation, sunburn, and the like) caused by abnormal facial metabolism of pigment. The product has the advantages of tiny particle sizes of spherical particles, obvious passive target function, excellent adaptability, homodromous property, fluidity and dispersion, strong penetrability, even texture, subtleness, lubricity and luster, is simple and convenient to use, and is comfortable without pungency and side effects; besides, the appearance is light yellow with slight opalescence, is glittering and translucent, clear and transparent, sticky but not viscous, thick but not dense, and oily but not greasy, has good stability, excellent curative effect, short industrialization cycle and high production efficiency, saves time, materials and energy sources, dose not need special devices and heat energy, and is easy for popularization and application.

The present invention relates to a vesicle oil displacement agent formed from a gemini surfactant, wherein a gemini surfactant and mineralized water are mixed to prepare the vesicle oil displacement agent, the mass concentration of the gemini surfactant is 0.02-0.2 wt%, the gemini surfactant molecule contains at least two negatively-charged polar hydrophilic groups and one or two hydrophobic groups, the single hydrophobic carbon chain length is 8-24, and the single hydrophobic carbon chain contains the benzene ring or naphthenic group. According to the present invention, the vesicle oil displacement agent formed from the gemini surfactant has the strong interface adsorption trend, the vesicle oil displacement agent and crude oil can form the ultra-low interface tension of 10<-3> mN.m<-1> without addition of any alkalis, the effect generation time is short, the interface tension can be reduced to 10<-3> mN.m<-1> within 10-15 min, and the vesicle oil displacement agent can be separately used or the vesicle oil displacement agent and a polymer can form a binary oil displacement system, and can be used in tertiary oil recovery so as to improve the crude oil recovery rate.

The invention discloses a natural efficient avian antibacterial agent, which is prepared from the following components in parts by weight: 5-10 parts of honeysuckle, 5-10 parts of cordate houttuynia, 10-15 parts of common andrographis herb, 8-10 parts of coptis chinensis, 2-10 parts of folium isatidis, 10-15 parts of radix isatidis, 5-10 parts of garlic, 3-8 parts of golden cypress and 10-20 parts of antimicrobial peptide. The invention also discloses a preparation method of the natural efficient avian antibacterial agent. The natural efficient avian antibacterial agent is simple in preparation method, low in cost, short in antibacterial effect time, non-toxic, and beneficial to environment protection; and the problem of drug resistance of pathogens does not exist.

The invention provides a method for fixing bioactive molecules, stem cells and other medicinal materials having treatment values in a surgical dressing. The bioactive substances are integrated and doped into the surgical dressing, so the method is particularly useful in the development of a novel dressing material system, and human mesenchymal stem cells and bioactive substances extracted from a patient (or allogeneic equivalent thereof) can be used in the wound or target operation position through the novel system by a medical staff in order to make the wound rapidly and effectively heal. The wound dressing comprises chitosans, chitosan oligomers, chitosan oligosaccharides, acetate acid gracial, gelatin, glycerin, purified water, mesenchymal stem cells and fibroblast growth factors.

The invention discloses an external preparation capable of relieving swelling and pain and a preparation method thereof. The external preparation is prepared from the following raw materials in parts by weight: 15-20 parts of herba sarcandrae, 9-15 parts of safflower carthamus, 9-15 parts of angelica sinensis, 9-15 parts of radix clematidis, 9-15 parts of lycopodium clavatum, 9-15 parts of speranskia tuberculata, 30-40 parts of camphor oil, 5-7 parts of borneol and 5-7 parts of menthol. The preparation method of the external preparation comprises the following steps: preparing an oil phase with the camphor oil, stearic acid and glyceride, preparing an aqueous phase with triethanolamine and a OP emulsifying agent, then adding the aqueous phase into the oil phase while stirring, adding an appropriate amount of essence as well as an extract prepared from herba sarcandrae and borneol-menthol ethanol liquid at the temperature of 40 DEG C, uniformly mixing by a melting method, and cooling, so as to obtain the product. The external preparation disclosed by the invention is quick in initial effect time, capable of effectively improving traditional Chinese medicinal syndromes, safe to use, free of toxic and side effects, safe and effective to treat knee osteoarthritis.

The invention discloses a method for breeding pinaeus monodon fries. The method comprises the following steps of: (1) preparing a bdellovibro nectophore bacterial suspension; (2) putting the bdellovibro nectophore bacterial suspension into a breeding pool to ensure that the content of bdellovibro nectophores in seawater is more than 101pfu / mL, and then aerating for 5-12 hours; (3) putting pinaeus monodon nauplii into the breeding pool with a density of 60-120 thousands / m<3>; (4) in the process of breeding, feeding baits to the pinaeus monodon nauplii at regular intervals, and putting the bdellovibro nectophore bacterial suspension at least every six days with a concentration of higher than 10pfu / mL after the pinaeus monodon nauplii are put into the breeding pool, wherein when the pinaeus monodon nauplii grow for 15 days or the body lengths of all the pinaeus monodon nauplii reach longer than 1 centimeter, the pinaeus monodon fries are obtained. In the invention, the number of times of changing water in the breeding process can be effectively reduced through putting the bdellovibro nectophore bacterial suspension in the process of water quality treatment and the bait putting and scientifically managing the pinaeus monodon fry breeding quality, and even water does not need to be changed, so that the yield of pinaeus monodon fries is improved, and the survival rate and the immunity of the pinaeus monodon fries are improved.

The invention relates to a Chinese medicinal ointment for treating burn or sore and ulcer and a preparation method thereof. The method comprises the following steps: mixing and pulverizing 50 to 200 grams of golden thread, 30 to 120 grams of cortex moutan, 15 to 60 grams of sanchi, 50 to 200 grams of halloysit, 50 to 200 grams of calamine, 10 to 40 grams of frankincense and 10 to 40 grams of myrrh to prepare a medicament A; mixing and pulverizing 50 to 200 grams of rhubarb, 50 to 200 grams of burnet and 50 to 200 grams of nutgall to prepare a medicament B; putting and soaking the medicament B in ethanol; percolating the solution; reclaiming the ethanol to obtain a thick paste of the medicament B; heating 1,000 to 4,000 grams of sesame oil to a temperature of between 150 and 250 DEG C; decocting the sesame oil for 1 to 2.5 hours; sequentially adding 50 to 200 grams of beeswax, the medicament A and the thin paste of the medicament B into the sesame oil and stirring the mixture when the temperature is reduced to 100 to 110 DEG C; and adding 10 to 40 grams of borneol into the mixture and stirring the mixture to prepare the Chinese medicinal ointment when the temperature is reduced to 40 to 50 DEG C.

The invention relates to an ultra-micronized megestrol acetate in which 100% of particle sizes are smaller than or equal to 10 mu m. The invention also relates to a pharmaceutical composition containing the ultra-micronized megestrol acetate, which comprises an effective quantity of ultra-micronized megestrol acetate and medically acceptable excipient, wherein the effective quantity is 80-160 mg of ultra-micronized megestrol acetate. The pharmaceutical composition can be prepared into dispersing tablets, common tablets and capsules and used for treating advanced breast cancer, advanced endometrial carcinoma, renal carcinoma, prostatic cancer and oophoroma, and can improve the appetite and the cachexia of patients with advanced tumors.

The invention relates to weight-reducing tea. The weight-reducing tea is mainly prepared from the following materials according to a certain weight ratio: lotus leaf, roselle calyx, lemon, sour orange, wild mint herb, ass-hide gelatin, lotus seeds, green tea, epigallo catechin gallate and xylooligosaccharide. The materials can be prepared into tea beverage, instant tea and teabag. The tea provided by the present invention has effects of qi promoting, body fluid regeneration, intestine moistening and bowel relaxing. The total effective rate of the tea for treating habitual constipations is more than 87%. In addition, the tea is easy to be drunk, and has significant treatment and health effects.

The invention relates to an external pharmaceutical composition preparation with functions of resisting inflammation, reducing swelling and relieving pain, which is characterized in that the preparation is prepared by the following effective component raw materials in weight percent of the whole preparation: 0.01 to 20 percent of escin and / or pharmaceutically acceptable salt thereof, 0.01 to 10 percent of diclofenac or pharmaceutically acceptable salt thereof, and the balance being accessories. The external pharmaceutical composition can be made into any pharmaceutically acceptable external dosage form. The preparation can be used for treating symptoms, such as arthralgia, hyperosteogeny, gout, neuropathic pain, injuries from falls, chronic strain diseases and various closed injuries, and the like, and has strong practicability.

The invention discloses a compound isosorbide mononitrate aspirin sustained-release capsule preparation. The compound isosorbide mononitrate aspirin sustained-release capsule preparation is characterized by comprising an isosorbide mononitrate sustained-release capsule preparation and an aspirin enteric-coated preparation, wherein the isosorbide mononitrate sustained-release capsule preparation contains 40-80 parts by weight of isosorbide mononitrate and comprises an immediate-release pellet with 30 percent of isosorbide mononitrate and a sustained-release pellet with 70 percent of isosorbide mononitrate, and the aspirin enteric-coated preparation contains 50-90 parts by weight of aspirin. The invention also provides a preparation method of the compound capsule preparation. With the adoption of the compound isosorbide mononitrate aspirin sustained-release capsule preparation, the curative effects are better improved, the adverse reaction due to stimulation from the aspirin to a gastric mucosa is better reduced, and meanwhile, the isosorbide mononitrate can also satisfy the requirement of stable release in a stomach.

The invention belongs to the technical field of blast furnace iron making, and particularly relates to titanium-containing powder for blast furnace protection and a blast furnace protection method for injecting the titanium-containing powder through a blast furnace coal injection system. The content of TiO2 in the titanium-containing powder ranges from 30 wt% to 90 wt%, and by weight percent, the titanium powder with the granularity being smaller than 200 meshes accounts for 40%-100%. The titanium-containing powder and pulverized coal are injected into a blast furnace together through the blast furnace coal injection system. The furnace protection method comprises the following steps that firstly, the titanium-containing powder and the pulverized coal are evenly mixed; and secondly, the titanium-coal mixture obtained after mixing is placed in an injection tank of the blast furnace coal injection system, conveyed to a blast furnace tuyere through an injection pipeline and finally injected into the blast furnace through the tuyere. When the titanium-containing powder is injected, normal coal injection is not stopped, the titanium-containing powder is injected evenly, and uniformity and stability of a blast furnace hearth are guaranteed; the pulverizing and injection processes do not need to be changed, the phenomenon of segregation of the pulverized coal and the titanium powder is not generated, the combustibility of titanium coal is not changed in comparison with the pulverized coal, and a mill and the injection system are not influenced.

The invention belongs to the field of Chinese medicine pharmacy, and relates to an application of a stizolobium cochinchinensis seed extract to preparation of a medicament for treating a Parkinson's disease accompanied by sleep disorder. The stizolobium cochinchinensis seed extract mainly comprises levodopa and stizolobium cochinchinensis seed guanidine components which are purified and combined respectively for preparing a medicament for treating Parkinson's diseases accompanied by sleep disorder of mammals including human beings. As proved by the result of an animal experiment, the stizolobium cochinchinensis seed compound extract can be used for improving the sleeping effect, and has a similar hypnotic effect to a calming effect; the pentobarbital sodium sleeping time can be prolonged, and the anti-shock effect is similar to that of levodopa; and the toxic and side effects are weak. The stizolobium cochinchinensis seed compound extract disclosed by the invention has the advantages of higher bioavailability, shorter response time, longer action maintaining time and the like, can be used for effectively treating Parkinson's diseases accompanied by sleep disorder of mammals including human beings, and has a wide application prospect.

A dropping pill o f the common haw-leaf flavone is prepared from common haw-leaf flavone, polyethanediol and poloxamer. Its advantages are quickly curative effect and high biological utilization rate.

The invention relates to a composite tramadol hydrochloride formulation and preparation process, wherein the compound preparation can be made into the forms of capsules or dispersing tablets, each 1000 capsules or 1000 dispersing tablets comprise tramadol hydrochloride 40-45g, acetaminopher 300-350g, sodium carboxymethyl starch 7.5-25g, and magnesium stearate 2.5-5g.

Disclosed is a Chinese medicinal composition for preventing and treating cardiovascular and cerebrovascular diseases, wherein the medicament comprises the following raw material herbs (by weight portion): American ginseng 1-80 parts, notoginseng 1-80 parts, schisandra chinensis 1-50 parts, root of red rooted saliva 5-80 parts, borneol 0. 1-10 parts.

The invention provides a hydrobromic acid lappaconitine solid lipid nano particle and a preparation method thereof. The hydrobromic acid lappaconitine solid lipid nano particle is prepared from the following components, by weight percent: 0.1-1% of hydrobromic acid lappaconitine, 1-8% of lipid material, 0-5% of phospholipid, 0.5-10% of emulsifying agent and the balance water. The preparation method comprises the following steps: mixing the emulsifying agent and the water fully and evenly and preparing a water phase; mixing the hydrobromic acid lappaconitine, the lipid material and the phospholipid fully, melting and preparing an oil phase; heating the water phase and the oil phase respectively to 65-85 DEG C, adding the water phase into the oil phase under a stirring condition and preparing primary emulsion; emulsifying the primary emulsion at high pressure evenly and obtaining suspensoid liquid; and putting the suspensoid liquid under a condition of 0-4 DEG C, cooling, solidifying andpreparing the hydrobromic acid lappaconitine solid lipid nano particle. The invention adopts a high-pressure even emulsification method to prepare the hydrobromic acid lappaconitine solid lipid nanoparticle, does not need to use an organic solvent and is suitable for large industrialized production.

The invention discloses a method for preventing and treating soil insects by entomopathogenic nematodes. The method is characterized by comprising the specific steps: (a) preparing an entomopathogenic nematode suspension; (b) applying the entomopathogenic nematode suspension at a larval stage of the soil insects in a manner of enabling the entomopathogenic nematode suspension to be uniformly distributed to the land surface of crop soil; and (c) infecting larvae of the soil insects in the soil by the entomopathogenic nematodes in the entomopathogenic nematode suspension, so as to prevent and treat the soil insects. The method is a pollution-free natural-enemy biological control technology and has the characteristics of being convenient in application, high in host-searching capability, high in infected killing effectiveness, high in effect taking speed, safe to human and livestock, natural enemies and environments and the like, the defects of the traditional microbial agent biopesticides that the effect taking speed is low, resistance is easy to generate, the soil insects cannot be prevented and treated, and the like are broken through, and the soil insects can be prevented and treated instead of high-toxicity high-residue chemical pesticides, so that the method not only has ecological significance, but also has important environment-friendly significance.

The invention discloses a face cleaning product with acne treating effect and a preparation method of the face cleaning product. The cleaning product is composed of a water-washing type face cleaning mud base material and a traditional Chinese medicine compound preparation, wherein the traditional Chinese medicine compound preparation is composed of following raw materials according to a certain ratio: viola philippica, cape jasmine fruits, rheum officinale, paeonia veitchii, cortex moutan, coptis chinensis franch, dandelions, fructus forsythiae, gypsums, periostracum cicada, spina gleditsiae, borneol and mirabilite. The preparation method comprises the following steps: decocting the raw materials of the traditional Chinese medicine compound preparation according to a prescription dosage with water and extracting a concentrated solution; then adding the concentrated solution of the traditional Chinese medicine compound preparation into the preparation step of water cleaning type face cleaning mud to obtain the face cleaning product. According to the face cleaning product with the acne treating effect and the preparation method of the face cleaning product, traditional compound traditional Chinese medicines are combined with the modern water cleaning type face cleaning mud; the face cleaning product is convenient to carry and is tightly contacted with the face when being used; effective components can be sufficiently contacted with an affected part, so that the good treating effect is realized.

The invention provides a traditional Chinese medicine composition for treating acute sinusitis and a preparation method thereof. The traditional Chinese medicine composition comprises an oral medicine and an external-use medicine. The oral medicine comprises the following raw materials: fortune eupatorium herb, Chinese angelica, biond magnolia flower, manchurian wildginger, long pepper, small centipeda herb, Siberian cocklour fruit, honeysuckle flower, suberect spatholobus stem, lilac pink herb, ginseng leaves, astragalus root, coptis, gentian root, lycium berry, pueraria root, arctium fruit, prunella spike, feather cockscomb seeds, radix liriopes, dendrobium, silybum marianum, rhizoma polygonati, radix acanthopanacis senticosi and licorice root; and the external-use medicine comprises the following raw materials: the biond magnolia flower, the manchurian wildginger, the long pepper, the small centipeda herb, the Siberian cocklour fruit, perilla leaves, mint, ephedra, lygodium spore, ligusticum root, Yuzhou uniflower swisscentaury root, achyranthes root, cowherb seeds, folium ilicis purpurea, radix bupleuri, cornu bubali, Japanese ampelopsis root, coptis, akebia fruit, tangerine peel, musk and the licorice root. The traditional Chinese medicine composition has the advantages that the efficiency for treating the acute sinusitis is high, the time of taking effect is faster, the pain of a patient can be quickly relieved within a short time, the cure rate is high, and the recurrence rate is low.

The invention relates to the technical field of alopecia treatment, and discloses a traditional Chinese medicine composition for preventing alopecia, growing hair, controlling oil and removing dandruff. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 18-28 parts of ginseng, 18-28 parts of cacumen biotae, 15-25 parts of astragalus membranaceus, 11-21 parts of polygonum multiflorum, 15-25 parts of salvia miltiorrhiza, 10-15 parts of frosted mulberry leaves, 10-15 parts of radix rehmanniae recen, 10-15 parts of fructus viticis, 10-15 parts of rhizoma zingiberis, 10-15 parts of angelica sinensis, 10-15 parts of radix notoginseng, 5-15 parts of leech, 5-15 parts of radix sophorae flavescentis, 5-15 parts of safflower carthamus, 5-15 parts of pricklyash peel, 5-15 parts of liquorice roots, 2.5-12.5 parts of dandelion and 2.5-12.5 parts of Chinese caterpillar fungus. According to the composition, the single product is externally used, the use is simple and convenient, the effect taking time is short, the batch of new vellus hair can be seen by naked eyes in one month, the visual improvement effect is significant in three months, a series alopecia period and the adverse reaction do not exist, the obvious increase of body hair does not exist, the multi-layer effect is provided, the hair quality is significantly improved, the hair root is strong and straight, and the hair stem is thick and strong; the effects of controlling oil, removing dandruff and relieving itching are obvious, and the effect on head seborrheic dermatitis is obvious.

Internal-dermal formulations of RS—, S—, or R-2-[2-(N-phenyl-N-2-indanyl)aminoethyl]piperidine causing intradermal accumulation of said piperidine and intended for the treatment of neuropathic pain are provided, as well as a method of inducing the relief of pain using the compounds.

The invention belongs to the field of pharmacy, and particularly relates to a compound reserpine orally disintegrating tablet for treating hypertension and a preparation method of the compound reserpine orally disintegrating tablet. The compound reserpine orally disintegrating tablet is prepared from the following raw and auxiliary materials in parts by weight: 0.03 part of reserpine, 1 part of hydralazine hydrochloride, 0.025 part of cyclopenthiazide, 1.5 parts of hydrochlorothiazide, 2 parts of promethazine hydrochloride, 30 parts of potassium chloride, 5 parts of rutin, 2.5 parts of phosphate chloroquine, 1 part of vitamin B1, 1 part of vitamin B6, 2-10 parts of a stabilizer fumaric acid and other pharmaceutical adjuvants. An experiment result shows that the orally disintegrating tablet is short in onset time, long in medicine duration time, and convenient for treatment of a patient for a long period of time; the medication safety is improved; meanwhile, the prescription is high in process stability, and is free of effects of environmental temperature and humidity; and the difference between batches of the preparations is significantly reduced; and the stability of a sample is improved.

Dermal and mucosal formulations of 2-[2-(N-phenyl-N-2-indanyl)aminoethyl]piperidine, characterized by rapid dermal and mucosal absorption and long duration of therapeutic activity are provided. Also provided are solutions of 2-[2-(N-phenyl-N-2-indanyl)aminoethyl]piperidine for injection, characterized by short onset time and long duration of activity. Formulations containing both 2-[2-(N-phenyl-N-2-indanyl)aminoethyl]piperidine and capsaicin are also provided.

The invention provides a processing agent for polyolefin and alloy thereof, comprising the following blended components: oligomer and polyprotic acid, wherein the molar ratio of the oligomer to the polyprotic acid is from 1:0.1 to 1:10; the oligomer is linear or short branched chain oligomer, of which the molecular weight is from 2000 to 20000, and two ends or one end of the oligomer is provided with polar end groups or a polar end group; and the polyprotic acid is organic polyprotic acid or inorganic polyprotic acid. The processing agent has the advantages of small volume of addition, short effective time, favorable viscosity effect and the like when used in the polyolefin and the alloy thereof. By adopting an acid modifying method of acid modification, the heat resistance of the oligomer is improved so that the decomposition problem is not existed under the normal processing temperature and the product can not fade.