41 results about "Gastrointestinal bleeding" patented technology

The disclosure relates to a device and method such as for treatment of a gastrointestinal perforation and a gastrointestinal bleeding. The device can be a balloon catheter that controls bleeding by pressing on a bleeding area or / and prevents the gastrointestinal contents trespassing outside a gastrointestinal lumen into a body cavity by blocking an opening in the luminal wall or blocking the colon distal or proximal to the perforation. The preferred device is inserted using an endoscope and allows to partially or completely withdraw an endoscope while leaving the balloon at the target area. The device and method can facilitate ceasing a colonic bleeding and blocking colonic perforation.

A method for determining if blood in a stool sample originated from the upper or lower gastrointestinal tract. This includes a method for purifying and concentrating hemoglobin and its products from a stool sample to allow a simple and sensitive spectrophotometric analysis. A rapid, noninvasive determination of whether the blood originated from an upper gastrointestinal or lower gastrointestinal site is made on the basis of changes in the absorption spectra of hemoglobin that occur when hemoglobin is exposed to a highly acidic environment.

The invention relates to a novel oral enteric preparation which is composed of 0.1-1000mg of Grel drugs, or medically acceptable salts, ester or derivatives, 37.5-325mg of aspirin and at least one medically acceptable load, wherein the Grel drugs, or medically acceptable salts, esters or derivatives are clopidogrel, prasugrel, brilinta, sarpogrelate, ozagrel, anagrelide, pamicogrel, or medically acceptable salts, ester or derivatives, preferably, clopidogrel sulfate. The oral enteric preparation is used for curing acute coronary syndrome (ACS), angor pectoris, stroke, myocardial infarction or cardia cerebrovascular diseases of patients. According to the oral enteric preparation, adverse reactions such as functional gastrointestinal disorders, nausea, vomit, gastritis, concealed hemorrhage, ulcer exacerbation and gastrointestinal bleeding caused by strong stimulus of aspirin to stomach can be avoided.

A gastrointestinal bleeding noninvasive monitoring system belongs to medical apparatus technical field, wherein a miniature hemoglobin detecting device which enters into gastrointestinal tracts of human body through oral taking can realize 24-hour noninvasive detection of hemoglobin content value in gastrointestinal tracts and can transmit the value outside human body through wireless transmission; a bleeding spot locating device detects position information of the miniature hemoglobin detecting device and transmits detecting results to a record storage device through conducting wire; the record storage device receives gastrointestinal hemoglobin content value transmitted by the miniature hemoglobin detecting device through wireless transmission and stores data of gastrointestinal hemoglobin content value, position information of the miniature hemoglobin detecting device and detecting time information according to predetermined format; a gastrointestinal bleeding diagnosis-analysis system which is arranged outside human body reads and processes the data stored inside the record storage device. The invention can realize 24-hour noninvasive monitoring of gastrointestinal bleeding under normal physiological status of human body.

The invention discloses an intelligent detection system for gastrointestinal hemorrhage, belonging to the technical field of medical appliances. The intelligent detection system comprises a micro gastrointestinal blood color detection device, a bleeding point positioning device, an in-vitro data storage device and a gastrointestinal bleeding diagnosis analysis system, wherein the micro gastrointestinal blood color detection device enters the gastrointestinal tract by being taken orally and is applied to noninvasive detection and wireless emission of gastrointestinal hemorrhage amount information; the bleeding point positioning device is used for detecting the in-vivo position information of the micro gastrointestinal blood color detection device and transmitting the in-vivo position information to the in-vitro data storage device through a lead; the in-vitro data storage device is used for receiving and storing the gastrointestinal hemorrhage amount information transmitted by the micro gastrointestinal blood color detection device and the position information transmitted by the bleeding point positioning device; and the gastrointestinal bleeding diagnosis analysis system is used for reading and processing data stored in the in-vitro data storage device. The intelligent detection system can be used for detecting in a painless and noninvasive way without performing gut purge, and physiological parameters such as the pH, pressure and the like of the gastrointestinal tract of a human body do not influence the detection result.

The present invention relates to a kind of medicine composition, hemostatic beautyberry dripping pill, with functions of clearing away heat and toxic material and astringing to arrest bleeding and for treating gastrointestinal bleeding, hematochezia, traumatic breeding, etc. The present invention has high bioavailability, fast medicine release, fast acting, high effective content, taking convenience and low cost. The manyprickle acanthopanax -ginseng -astragalus dripping pill is prepared with Chinese medicinal material beautyberry leaf and medicine carrier as matrix.

The invention discloses stomach nourishing medicinal liquor. The stomach nourishing medicinal liquor is prepared from the following chosen raw herbal materials: wild lilac, semen pharbitidis, ginger, mango leaves, agilawood, lindera aggregata, schisandra chinensis, dandelion, radix codonopsis, radix paeoniae rubra, sword beans, cinnamon, polygonum multiflorum and Chinese rice wine. The stomach nourishing medicinal liquor disclosed by the invention can be used for strengthening the spleen and nourishing the stomach, inhibiting gastrointestinal peristalsis and hyperacidity, repairing peptic ulcer and stopping gastrointestinal bleeding, and has very good effects of nourishing the stomach and strengthening the spleen, repairing stomach problems, promoting digestion and relieving stasis, treating spleen deficiency with dampness-heat, promoting urination and defecation and treating a stomachache.

The present invention relates to a biocompatible, foldable, thin profile, low mass and high surface area, chitosan dressing, optionally modified with catechol, and suitable for treating bleeding in a physiological environment, e.g. gastrointestinal tract. The characteristics and structures of the chitosan dressing are provided. Methods of making and using the chitosan dressing are also provided.

A medical device designed for gastrointestinal endoscopists who require a more effective means of removing blood clots from the upper GI tract during episodes of upper GI bleeding. It is an endoscope attachment that breaks down blood clots, allowing them to be removed through the existing endoscope suction channel. Current methods are time-consuming, ineffective, and often life-threatening. This device offers an efficient alternative that makes the procedure quicker, safer, easier, and more cost-effective. The product offers simple solution to a life-threatening problem.

The invention discloses a Chinese medicinal mixture for treating upper gastrointestinal bleeding. The Chinese medicinal mixture comprises the following Chinese medicinal components in part by weight: 6 to 10 parts of calcined ophicalcite, 6 to 8 parts of cuttlebone, 2 to 5 parts of pseudoginseng root, 2 to 5 parts of rhubarb and 5 to 8 parts of liquoric root. The components of the mixture are the common pure Chinese traditional medicines, and the mixture has rational compatibility, does not have toxic or side effect and can immediately stop bleeding for an upper gastrointestinal bleeding symptom during use.

The invention discloses an application of honokiol in inhibiting streptococcus suis or a biofilm of the streptococcus suis. The inventors find that the honokiol or a pharmaceutically acceptable salt of the honokiol has the effect of inhibiting the formation of the streptococcus suis and the biofilm or killing the streptococcus suis in the mature biofilm; the inventors use a standard micro-dilutionmethod to measure the MIC value of the honokiol against the streptococcus suis, and results show that the MIC value of the honokiol against the streptococcus suis is close to the MIC value of antibiotics; and the inventors use a high-throughput static biofilm system method to construct an in-vitro biofilm model, and find that the subinhibitory-concentration honokiol can reduce the formation of the streptococcus suis biofilm and destroy the three-dimensional structure of the streptococcus suis biofilm through research results of a crystal violet method and scanning electron microscopy. The invention discloses a pharmaceutical composition for inhibiting the streptococcus suis or the biofilm by using the honokiol as a main active ingredient, and the pharmaceutical composition has good safety, and does not have the problems of drug residues, bacterial drug resistance, allergic reactions and gastrointestinal bleeding.

The invention relates to a composition for treating a gastric ulcer combined gastrointestinal bleeding. The composition comprises the following active components in parts by weight: 8-25 parts of ginsenoside Re, 10-30 parts of ginsenoside Rg3 and 5-20 parts of ginsenoside Rh1. The composition has the effects of obviously improving the gastric mucosal lesion and gastric mucosal lesion, promoting the blood coagulation and stopping bleeding, and is capable of effectively treating and / or preventing gastrointestinal diseases of the gastric ulcer combined gastrointestinal bleeding and the like.

The invention belongs to the technical field of traditional Chinese medicine, and specifically relates to a traditional Chinese medicine composition for preparing a color Doppler ultrasound contrast agent, applications and a preparation method thereof. The traditional Chinese medicine composition is composed of the following raw materials: turtle shell, radix astragali, bletilla striata, cuttlebone, dried alum, egg shell, radix codonopsis, dried orange peel, semen cuscutae, and talcum powder. The provided traditional Chinese medicine composition can be used as a contrast agent used in the digestive tracts, and also has a pharmacologic effect, so the composition can be used to treat diseases such as gastrointestinal ulcer, gastrointestinal bleeding, and the like in clinic.

The invention relates to a preparation method of a traditional Chinese medicine composition of Hewei Jiangni Xiaopi and its preparation. The preparation is prepared from the following raw materials in the weight ratio: Pinellia 10-30g, Codonopsis 10-25g, and Radix Scutellariae 10-25g 20g, roasted licorice 10‑15g, dried ginger 10‑20g, pitted jujube 10‑30g, coptis 5‑10g, cinnamon 1‑5g, peeled amomum 5‑10g. The invention has the advantages of regulating immunity, inhibiting Helicobacter pylori infection, protecting the gastric mucosal barrier and gastrointestinal bleeding, regulating cold and heat, eliminating spleen and dispelling stagnation, and having no adverse reaction, and the effect is like a drum.

The invention provides a compound comprising a proton pump inhibitor and a gastric mucosa protective agent and an application of the compound. The compound comprises the proton pump inhibitor and the gastric mucosa protective agent and can be directly mixed or indirectly connected through hydrogen bonds, co-crystallized sodium hydrate formed by hydrogen bond connection is more stable in property, and pharmacokinetic property is remarkably improved. Although the proton pump inhibitor and the gastric mucosa protective agent are different in action mechanism, the compound formed by the proton pump inhibitor and the gastric mucosa protective agent has unexpected synergistic effects and has a positive application prospect in the field of digestive ulcer and gastrointestinal bleeding treatment.

The invention provides a digestive tract hemorrhage image detection method used for a capsule endoscope. The method comprises the following steps of 1: after a patient swallows the capsule endoscope, acquiring an image in the digestive tract by the capsule endoscope, transmitting the image to a computer through wireless communication, and performing data preprocessing on the digestive tract image by the computer; and 2: performing point-like hemorrhage detection and face-like hemorrhage detection on the preprocessed digestive tract image, determining whether hemorrhage exists in the digestive tract or not, and marking a point-like hemorrhage region and a face-like hemorrhage region. According to the method, the hemorrhage in the image can be effectively identified, so that the working efficiency of doctors is improved.

The invention discloses a traditional Chinese medicine formula for treating gastrointestinal bleeding. The traditional Chinese medicine formula is prepared from the following medicinal raw materials in percentage by mass: 12-16g of humifuse euphorbia herb, 12-16g of sanguisorba officinalis and 12-16g of lalang grass rhizome; the medicinal raw materials are decocted in 750ml of water for 15-20min, an obtained decoction is cooled and dregs are removed; and an obtained traditional Chinese medicine is taken twice every day by 150-200ml in each time. The traditional Chinese medicine disclosed by the invention has functions of clearing away heat and toxic materials, cooling blood and stopping bleeding, and the like, and the traditional Chinese medicine is capable of rapidly treating gastrointestinal bleeding. The traditional Chinese medicine disclosed by the invention has the advantages of being good in curative effect, short in treatment course, low in cost, free from side effects, free from reoccurrence and the like, and a cure rate can reach 91% and above.

The present invention relates to surgical instruments used in combination with endoscopes during gastrointestinal procedures for clearing a surgical site of unwanted obstructions, such as blood and / or clots. More particularly, the irrigation devices according to the invention comprise a handle comprising valves for controlling fluid flow, at least one channel for transporting fluid, and a connection port adapted to communicate directly or indirectly with an endoscope for delivering fluid to and receiving fluid from and through the endoscope. The irrigation devices and systems incorporating them can be used in any endoscopic gastrointestinal surgical procedure to clean, clear, or evacuate an area of the gastrointestinal tract, such as the stomach, in cases of accidental poisoning, drug overdose, or gastrointestinal bleeding. The irrigation device according to the present invention is capable of clearing a stomach within seconds or up to 1-2 minutes.

The invention relates to a Chinese medicinal composition for treating hemorrhage of digestive tract, namely ulcer No. 2 powder. The Chinese medicinal composition is prepared from the following Chinese medicines in part by weight: 20 to 40 parts of bletilla, 10 to 35 parts of astragalus, 10 to 20 parts of Chinese angelica, 10 to 30 parts of cuttlebone, 5 to 20 parts of calcined oyster and 3 to 10 parts of plant soot, wherein on the basis of crude Chinese medicines, an appropriate excipient is added to prepare a medicinal preparation. The preparation method for the Chinese medicinal composition comprises the following steps of: crushing the six Chinese medicines into fine powder in the required weight ratio at normal temperature and normal pressure, sieving, mixing uniformly, sterilizing, packaging into separate bags, and preparing powder according to the conventional technology of the Chinese medicinal preparation, wherein other preparations also can be prepared according to the conventional technology of the Chinese medicinal preparation. The Chinese medicinal composition has the advantages of high pertinence, obvious curative effect, reasonable formula, moderate cost and no toxic or side effect, and is particularly practical.

The invention discloses stomach-nourishing medicinal wine. The stomach-nourishing medicinal wine comprises the following components in parts by weight: 30-40 parts of yellow rice wine, 15-25 parts ofpharbitis seed, 12-25 parts of agilawood, 5-10 parts of honeysuckle, 10-15 parts of polygonum multiflorum, 5-10 parts of hawthorn, 6-10 parts of fried immature bitter orange and 5-6 parts of clove. Through combination of the yellow rice wine with the pharbitis seed, the agilawood, the polygonum multiflorum and other medicinal materials, the stomach-nourishing medicinal wine effectively inhibits gastrointestinal motility, inhibits hyperacidity, repairs ulcers, stops gastrointestinal bleeding symptoms, effectively relieves stomach discomfort, and has a good therapeutic effect.

The invention relates to a pharmaceutical composition of ticagrelor and cilostazol, a preparation method of the pharmaceutical composition, and application of the pharmaceutical composition in medicines. The pharmaceutical composition has the effect of inhibiting or reversing atherosclerosis lipid plaques of artery blood vessel, in particular the effect of inhibiting or reversing atherosclerosis lipid plaques of coronary artery or carotid artery. The composition is able to effectively solve the problem due to interregnum of pharmaceutical function caused by occasionally missing ticagrelor, as well as reduce the possible cardiovascular and cerebrovascular diseases; in addition, the gastrointestinal bleeding can be greatly reduced, and the effect is far more than the effect of the composition of ticagrelor and aspirin.

The invention relates to a pharmaceutical composition of ticagrelor and cilostazol, a preparation method of the pharmaceutical composition, and application of the pharmaceutical composition in medicines. The pharmaceutical composition has the effect of inhibiting or reversing atherosclerosis lipid plaques of artery blood vessel, in particular the effect of inhibiting or reversing atherosclerosis lipid plaques of coronary artery or carotid artery. The composition is able to effectively solve the problem due to interregnum of pharmaceutical function caused by occasionally missing ticagrelor, as well as reduce the possible cardiovascular and cerebrovascular diseases; in addition, the gastrointestinal bleeding can be greatly reduced, and the effect is far more than the effect of the composition of ticagrelor and aspirin.

The present invention relates to a method for treating gastrointestinal bleeding in a subject with severe von Willebrand Disease comprising administering to the subject at least one dose of recombinant von Willebrand Factor (rVWF) ranging from about 40 IU / kg to about 100 IU / kg, wherein the first dose further comprises recombinant Factor VIII (rFVIII).

The invention discloses a Yunnan red medicine tablet, a preparation method and application thereof. Yunnan Hongyao Tablets are made of the following raw materials in parts by weight: Yunnan Hongyao 210-283, microcrystalline cellulose 5-8, sucrose powder 18-30, dextrin 12-15, magnesium stearate 3, talcum powder 3 , an appropriate amount of carboxypropyl methylcellulose 60% ethanol liquid; the parts by weight of the raw materials of Yunnan red medicine are: Panax notoginseng 20-30, Chonglou 55-65, Zijinlong 10-15, Cannabis 15 ~20, Jin Tie Suo 10~15, sliding leaf Dieda 20~28, jade grape root 20~30, Huangcaowu 35~40, Shichangpu 5~10, Southwest Huangling 20~30. Yunnan Hongyao Tablet is safe, non-toxic, has strong pharmacological effects and wide indications, and can be widely used in the preparation of medicines for treating or preventing stomach and duodenal ulcers, upper gastrointestinal bleeding, functional uterine bleeding, analgesia and anti-rheumatism.

The invention relates to the field of Chinese medicinal powder, in particular to a flesh engendering and skin growing Chinese medicinal powder and a preparation method thereof. The flesh engendering and skin growing Chinese medicinal powder comprises the following optimal weight parts of raw materials: 50 parts of pearl, 3 parts of dried alum, 50 parts of antler, 30 parts of concha haliotidis, and30 parts of propolis. The preparation method comprises the steps of: S1: raw material pretreatment; S2: wall-breaking crushing treatment; S3: premixing treatment; S4: drying treatment; S5: uniform mixing, weighing and packing. The Chinese medicinal powder provided by the invention can promote the self-repair of human skin and flesh damage, and has magical curative effect on burns, scalds, gastriculcer, gastrointestinal bleeding, postoperative nonunion of incisions, and diabetic toe necrosis, and has the advantages of convenient oral administration and external application, no toxic or side effect, fast effect, and maximum avoidance of the disadvantages brought about by other treatment means.

The invention discloses medicine for treating cancer and cardiovascular and cerebrovascular diseases through traditional and western medicine integration and a preparation method thereof. The medicine comprises western medicine components and Chinese medicine components, wherein the western medicine components comprise alprostadil, aspirin, ribonucleic acid and reduced glutathione; the Chinese medicine components comprise 12-30 g of rheum officinale, rhizoma cyperi, rhizoma sparganii, an anemone root, radix cynanchi paniculati, pharbitis seeds, a fresh water turtle shell, hericium erinaceus, dry toad skin, dung beetles, reeves's pheasants and ottelia alismoides. It is effectively avoided that aspirin will stimulate the gastric mucosa, so that gastrointestinal reaction such as nausea, vomiting and epigastric discomfort or pain is caused, and it is prevented that if people take the aspirin for a long term or take a large dosage of the aspirin, even gastrointestinal bleeding or anabrosis will happen. The medicine ingredients are mixed through an improved mixer, in this way, the anti-shake property and stability of a mixer case are greatly improved, the preparation efficiency of the medicine is improved, and the product cost for the medicine is lowered.

The invention discloses a method for making an anticoagulant gastric tube, which comprises the following steps: soaking the polyurethane tube body with ethanol solution for more than 1 hour at room temperature; taking out the polyurethane tube body and drying it naturally, and then rinsing it several times with distilled water; body immersed in CaCl 2 solution; shaking polyurethane tubing and CaCl 2 solution to fully combine the two; take out the polyurethane tube body and dry it naturally; mix heparin sodium solution and sodium alginate solution evenly with the same volume to form a mixed solution, put the polyurethane tube body in the mixed solution; shake the polyurethane tube body and the mixed solution to make the two Mix well; remove polyurethane tube and allow to dry. This production method makes the heparin sodium solution stably attached to the polyurethane tube body, reduces the formation of blood clots related to the gastric tube and external gastric tube in patients after upper gastrointestinal surgery and patients with major digestive bleeding, ensures smooth drainage in a short period of time, and promotes the treatment of patients. of rapid recovery. The invention is used in the field of medical gastric tube.

The invention discloses a composition of traditional Chinese medicines and a western medicine for treating angiitis and a preparation method of the composition. The composition of the traditional Chinese medicines and the western medicine contains the following raw materials in parts by weight: radix salviae miltiorrhizae, rhizoma chuanxiong, radix paeoniae rubra, semen persicae, flos carthami, sanguis draxonis, earthworms, leeches, radix achyranthis bidentatae, liquorice, astragalus membranaceus, angelica sinensis, herba ephedrae, rhubarb, rhizoma cyperi, rhizoma sparganii, saxifraga stolonifera, cynanchum paniculatum, semen pharbitidis, litsea pungens and aspirin. The defect that gastrointestinal reactions such as nausea, throw-up, epigastric discomfort or ache can be caused as gastric mucosa is irritated by aspirin can be effectively avoided, gastrointestinal bleeding or anabrosis which is caused in long-term taking can be prevented, and thus the composition can be relatively well popularized and applied. As an improved mixing machine is adopted to mix the medicines, the case shaking prevention property and the stability can be greatly improved, the medicine preparation efficiency can be improved, and the medicine production cost can be reduced.

The invention relates to a medicinal wine for treating hemorrhoids and a brewing method thereof. The medicinal wine for treating hemorrhoids of the present invention is characterized in that the medicinal wine is prepared by soaking Folium Folium Folium, green plantain flowers or stalks in corn wine, This medicated wine is taken internally and has the functions of regulating qi, smoothing qi, cooling blood, hemostasis, analgesia, etc. It can cure internal hemorrhoids, external hemorrhoids, mixed hemorrhoids, prolapse of the anus, gastrointestinal bleeding, etc. 15ml of this medicated wine each time, 3 times a day, Fifteen days is a course of treatment. Generally, one course of treatment can cure the hemorrhoids. In special cases, two to three courses of treatment can eradicate hemorrhoids without recurrence.