16 results about "Gastrointestinal bleeding" patented technology

The invention is applicable to the technical field of medical instruments, and provides an interventional therapy device for alimentary canal hemorrhage, which comprises an outer sleeve and a guide wire arranged in the outer sleeve, and further comprises a plurality of hemostatic clips, each hemostatic clip comprises a cylindrical body, a ball head is fixed at one end of each cylindrical body, and the other end of each cylindrical body is rotatably connected with two clamping jaws; a guide cavity is formed in the cylindrical body in the length direction, a guide block is slidably connected into the guide cavity, a tension spring is fixed to the end, close to the ball head, of the guide block, and the tail end of the tension spring is fixed into the guide cavity; when a plurality of hemostatic clips are sequentially connected end to end, the two clamping jaws on one hemostatic clip clamp the ball head on the adjacent hemostatic clip, so that the two adjacent hemostatic clips are in ball joint. A plurality of hemostatic clips can be placed in the outer sleeve at a time, a plurality of hemostatic clips can be used in sequence, the outer sleeve and the guide wire do not need to be repeatedly pulled out from a biopsy duct of an endoscope during use, then the surgical efficiency is improved, and surgical operation steps are simplified.

Provided herein are compositions for use in forming temporary occlusion of a target site and methods of making same. The compositions disclosed herein include rare-earth phosphates compositions for temporary occlusion of a target sites. The compositions can be used in a variety of medical indications, such as trauma, ambulatory transport, to prevent and / or control bleeding (e.g., organ bleeding, gastrointestinal bleeding, vascular bleeding, bleeding associated with an aneurysm, etc.).

1. Name of the product in this design: Suction connector (2). 2. Purpose of this design: To connect the suction connector (2) to the suction tube of the suction device when there is gastrointestinal bleeding. 3. The key design feature of this product is its shape. 4. The image or photograph that best illustrates the design's key points: a 3D model.

The invention discloses digestive tract hemorrhage suction equipment which comprises a suction assembly fixedly arranged on the side edge of a gastroscope, and the suction assembly and the gastroscope are fixed through a fixing part. The outer surfaces of the gastroscope and the suction assembly are fixedly coated with a coating layer; a stirring assembly is arranged in the suction assembly; in order to solve the problems that in the prior art, a suction hole channel of a common gastroscope is too small, and the blood clot suction efficiency is low, the suction assembly is designed, the suction head end of the suction assembly can be fixed to the front end of the gastroscope through combination and fixation between the suction assembly and the gastroscope and arrangement of an external coating layer, and the suction efficiency of the gastroscope is improved. The gastral cavity aspirator is provided with the aspirating assembly, so that hematocele in the gastral cavity can be effectively aspirated, the stirring assembly is arranged, large blood clots can be stirred and broken, and therefore it is guaranteed that when massive blood clots are formed, effective aspiration can also be guaranteed.

The present invention discloses an image detection method and system for gastrointestinal bleeding, which relates to the technical field of image detection. Based on the original data of the user to be detected and combined with the usage data of the capsule detection terminal in the data warehouse, the overall matching value between the user to be detected and each user is evaluated from two aspects of physical fitness and gastrointestinal peristalsis, so as to determine the set of detection body position and posture transformations of the user to be detected, with relatively high accuracy, ensuring the correctness of the posture of the user to be detected when using the capsule detection terminal for gastrointestinal bleeding examination, ensuring the smooth movement of the capsule detection terminal in the digestive tract, and improving the detection effect of the capsule detection terminal; based on the operation data of the capsule detection terminal of the user to be detected, it is judged whether there are problems such as image defects or too fast speed in the current capsule detection terminal, avoiding the influence on the recognition and determination of gastrointestinal bleeding of subsequent users to be detected, and ensuring the detection effect of the user to be detected.

The application provides a digestive tract hemorrhage locator, and relates to the field of medical devices, which comprises a probe-in mechanism; an inner part of the probe-in mechanism is fixedly connected with a monitoring structure, a driving mechanism, a second sliding mechanism and a storage mechanism, one side of the monitoring structure is fixedly connected with a first sliding mechanism and a control mechanism, the first sliding mechanism is movably connected with a rotating structure and the driving mechanism, the rotating structure is movably connected with the probe-in mechanism and the monitoring structure, the control mechanism is movably connected with the second sliding mechanism, and the storage mechanism comprises a medicine storage box, a protection box, an extension rod and a partition plate; the protection box is fixedly connected in the inner part of the medicine storage box, the extension rod is fixedly connected in the protection box, one end of the extension rod is fixedly connected with the partition plate through the protection box, and the partition plate is movably connected in the medicine storage box; the medicine storage box can effectively store the powdered medicine, and after the partition plate is lifted through the extension rod, the medicine can be discharged into the patient's body through the hollow slot B and the hollow slot A.

The present invention relates to the use of LAT1 inhibitors in the preparation of drugs for treating atherosclerosis, belonging to the field of pharmaceutical technology. To solve the clinical problem that there is still a relatively high residual risk in advanced atherosclerosis under the current treatment strategies, the present invention provides the use of LAT1 inhibitors in the preparation of drugs for treating atherosclerosis. The present invention has confirmed that LAT1 inhibitors delay the progression of atherosclerosis by inhibiting the entry of leucine into macrophages, reducing plaque area and necrotic core; at the same time, LAT1 inhibitors can also enhance the mitochondrial function of macrophages, increase fatty acid oxidation, reduce lipid deposition in atherosclerotic plaques, increase the stability of atherosclerotic plaques, delay the development of atherosclerosis induced by a high-fat diet, and can be applied to patients in whom the use of other types of anti-atherosclerotic drugs is limited due to diseases such as combined gastrointestinal bleeding, aortic aneurysm or tumor.

The absorbable gastrointestinal hemorrhage hemostasis tube comprises a first composition and a second composition, the first composition comprises polypeptide capable of being self-assembled in a water phase, and the second composition comprises methacrylamide gelatin (GelMA) and a photoinitiator; the polypeptide comprises 1-2 fragments R1 and 2-4 fragments R2, wherein the fragment R1 is connected to the N end or the C end of the fragment R2 or between the two fragments R2 through an amido bond; wherein the amino acid sequence of the fragment R1 is FLIVGSII. By means of various digestive enzymes in the digestive tract, different pH value environments and the scouring effect of fluid, the hemostasis tube can keep stable and play a role in the environments. For example, the structures and properties of polypeptides and GelMA enable them to resist the decomposition of digestive juice, maintaining their structural integrity of hemostasis in a dynamic environment within the digestive tract until the hemostasis process is completed and absorbed.

The application relates to the field of medical systems, in particular to a gastrointestinal hemorrhage prediction analysis system and method based on information planning, which analyzes the damage of food to the digestive tract and the influence of gastrointestinal hemorrhage abnormalities on the food through a multi-source data fusion method, judges the damage risk of food to the digestive tract, improves the edible safety of food, analyzes the chewing habit through a multi-layer perception machine neural network model, evaluates the influence of chewing on food, and then judges the damage of food to the digestive tract after chewing, and improves the accuracy of the damage risk judgment of food to the digestive tract.

This invention relates to a traditional Chinese medicine composition for delaying the progression of kidney deficiency and blood stasis syndrome in diabetic nephropathy, its application, and preparation method. The composition is made from Astragalus membranaceus, Salvia miltiorrhiza, Paeonia lactiflora, Anemarrhena asphodeloides, Phellodendron chinense, Cistanche deserticola, Scutellaria baicalensis, Euonymus alatus, Schisandra chinensis, raw oyster shell, Plantago asiatica, and Artemisia annua. It has the effects of nourishing the kidneys, clearing heat, eliminating toxins, and unblocking the meridians. This traditional Chinese medicine composition can effectively delay the decline in renal function in patients with massive proteinuria during the diabetic nephropathy stage, improve the clinical symptoms of patients with kidney deficiency and blood stasis syndrome, and improve their quality of life. Simultaneously, it has a low risk of hyperkalemia and gastrointestinal bleeding, and no significant damage to liver function has been observed, indicating high safety.

The application discloses a kind of intelligent early warning methods of gastrointestinal hemorrhage based on multi-source data fusion, it is related to medical information processing technical field, including: the clean data tensor of target patient is collected, and target feature group is extracted;According to target feature group, the first significant deviation moment of target patient feature is determined, and the elapsed time is obtained according to current time;The difference between estimated delay time and elapsed time is calculated as remaining safety time;According to remaining safety time, trigger early warning, record actual bleeding condition;The prior art relies on whole body physiological signal to cause the problem of early warning lag, realize the signal perception of early stage of bleeding;And based on remaining safety time, realize the leap from qualitative risk prompt to quantitative time early warning, further improve the reliability and anti-interference ability of early abnormal signal detection.

The application relates to the technical field of medical data mining, in particular to a digestive tract hemorrhage risk assessment system based on deep learning. Firstly, non-structural text data is preprocessed to determine key words and non-key words; then, in combination with risk features represented by text data changes and the influence of aspirin on hemorrhage risk, form risk feature values are determined in the dimension of text form; then, in combination with semantic information of the text data and the text semantics of each risk link corresponding to the digestive tract risk, correlation analysis is carried out, semantic risk feature values are determined in the dimension of semantic information; finally, in combination with the form risk feature values and the semantic risk feature values, the attention weight of each text evaluation dimension is determined, and a neural network model is adjusted according to the attention weight, so that the accuracy of the output digestive tract hemorrhage risk assessment coefficient is higher.

Cell death of mammalian cells is achieved by a treatment apparatus comprising a controller, a drive circuit controlled by the controller to generate drive pulses, and at least two electrodes or electrode portions linked with the drive circuit for delivering the pulses. The apparatus may be configured for treatment of conditions such as diabetes, obesity and GI tract bleeding. The controller causes the drive circuit to provide pulses in: (a) a first group of pulses sufficient to create / open cell pores and / or disrupt cell membranes of tissue near the electrodes, (b) a second group of one or more pulses with lower voltages (e.g., electrophoretic pulses), and (c) repetition of (a) and (b) in N cycles, N having a value of 0 to 100. This may achieve cell death with lower voltages and less patient discomfort. Artificial intelligence and / or machine learning models and algorithms are described.

The invention discloses a preparation method of a traditional Chinese medicine fire calcined carbon powder honeyed pill for treating hemorrhage of various symptoms, and relates to the technical field of traditional Chinese medicine preparations, and the preparation method comprises the following steps: (1) raw material pretreatment: taking eucommia ulmoides, pollen typhae, trogopterus dung, pseudo-ginseng, pig trotter shell, radix aconiti lateralis preparata and liquorice, cleaning and drying; (2) crushing: mixing and crushing the traditional Chinese medicinal materials dried in the step (1), and sieving with a 60-100-mesh sieve to obtain traditional Chinese medicinal coarse powder.Clinical observation shows that for various refractory hemorrhage (such as lung cancer, alimentary canal and metrorrhagia), people who stop bleeding take a quite high proportion within 2-4 hours after the traditional Chinese medicinal composition is taken for the first time, which indicates that the traditional Chinese medicinal composition has a rapid hemostatic effect, and has no toxic or side effect. 60 treated cases cover bleeding of multiple systems such as respiration, digestion and genitourinary systems, the total hemostasis rate is high, it is proved that the traditional Chinese medicine preparation has a good effect on bleeding caused by multiple causes of diseases, and the effective key guarantee of the preparation is achieved by conducting stir-frying twice, particularly conducting a precisely-controlled carbonization process, so that the drug properties of the medicinal materials are directionally converted, and the astringency hemostasis effect is enhanced.

The present invention relates to a biocompatible, foldable, thin profile, low mass and high surface area, chitosan dressing, optionally modified with catechol, and suitable for treating bleeding in a physiological environment, e.g. gastrointestinal tract. The characteristics and structures of the chitosan dressing are provided. Methods of making and using the chitosan dressing are also provided.