Patents
Literature
Hiro is an intelligent assistant for R&D personnel, combined with Patent DNA, to facilitate innovative research.
Hiro

80 results about "Fecal occult blood" patented technology

Fecal occult blood (FOB) refers to blood in the feces that is not visibly apparent (unlike other types of blood in stool such as melena or hematochezia). A fecal occult blood test (FOBT) checks for hidden (occult) blood in the stool (feces). It is a screening test whose main and only purpose is for colorectal cancer.

Devices and methods for sample collection and analysis

The present invention provides devices, methods, and kits for the collection of a solid or semi-solid sample and analysis for the presence, absence, or quantity of an analyte. The invention provides a collection slide having a first card and a second card. The first card has a sample collection area. The first and second cards have orifices allowing the passage of fluid through the sample collection area, and the cards are hingeably connected to each other. The invention also provides an assay device having a housing with a test element, a results window, and a docking area for receiving and engaging the collection slide. In one embodiment the collection slide and device can be used to detect the presence of fecal occult blood (human hemoglobin) in a stool sample. Many other embodiments are described herein.
Owner:ABBOTT RAPID DIAGNOSTICS INT UNLTD

Devices and methods for sample collection and analysis

The present invention provides devices, methods, and kits for the collection of a solid or semi-solid sample and analysis for the presence, absence, or quantity of an analyte. The invention provides an assay device having a housing containing a test element, a results window, and a docking area for receiving and engaging a sample collection slide. The docking area has a sample receiving orifice with one or more fluid transfer structures. In one embodiment the collection slide and device can be used to detect the presence of fecal occult blood (human hemoglobin) in a stool sample. Many other embodiments are described herein.
Owner:ACON BIOTECH (HANGZHOU) CO LTD

Kit for early stage colorectal cancer auxiliary diagnosis and use method and detection system thereof

InactiveCN106399570ANo detection blind zoneHigh test acceptanceMicrobiological testing/measurementBiological material analysisViral OncogeneGenes mutation
The invention provides a kit for early stage colorectal cancer auxiliary diagnosis and a use method and a detection system thereof. The kit comprises a nucleic acid isolation and purification reagent, a DNA (deoxyribonucleic acid) sulfite conversion reagent, a KRAS (kirsten rat sarcoma viral oncogene homolog) gene mutation detection reagent, a BMP3 (bone morphogenetic protein 3) and NDRG4 (N-myc downsteam regulated gene 4) gene methylation detection reagent and a fecal occult blood detection reagent, wherein the nucleic acid isolation and purification reagent is used for separating and purifying the human DNA in a faeces sample; the DNA sulfite conversion reagent is used for performing sulfite conversion on the purified partial human DNA, and is used for subsequent BMP3 and NDRG4 gene methylation detection. Through detecting two kinds of indexes of DNA and fecal occult blood in the faeces sample in a combined way, the kit provided by the invention is used for the early stage screening of the colorectal cancer. Compared with an FOBT (fecal occult blood test) detection method, the kit provided by the method can realize higher sensitivity on the detection of colorectal cancer, particularly the developing period tumor.
Owner:HANGZHOU NEW HORIZON HEALTH TECH CO LTD

Sanitary and compact fecal occult blood collector

A biological sample collection and test kit and a method of using the kit are disclosed in the application. The kit includes a swab, having a sample collection portion, a cover for covering the sample collection portion of the swab for hygienic purpose. Also disclosed is a package for the swab and the cover.
Owner:ABBOTT RAPID DIAGNOSTICS INT UNLTD

Devices and methods for sample collection and analysis

The present invention provides devices, methods, and kits for the collection of a solid or semi-solid sample and analysis for the presence, absence, or quantity of an analyte. The invention provides a collection slide having a first card and a second card. The first card has a sample collection area. The first and second cards have orifices allowing the passage of fluid through the sample collection area, and the cards are hingeably connected to each other. The invention also provides an assay device having a housing with a test element, a results window, and a docking area for receiving and engaging the collection slide. In one embodiment the collection slide and device can be used to detect the presence of fecal occult blood (human hemoglobin) in a stool sample. Many other embodiments are described herein.
Owner:INVERNESS SWITZERLAND GMBH

Feces color detection device

InactiveUS20170303901A1Easy to observeFacilitating daily monitoringSurgeryVaccination/ovulation diagnosticsMedicineAnimal feces
A plurality of color sensing sections are attached to a toilet seat so as to test a health state or a fecal occult blood portion every time by capturing the feces surface color during defecation. Before feces which have been excreted from a body sink into a water-seal portion, the circumference of the feces is optically captured to detect the color of the surface of the feces. By monitoring changes in color, the health state of the defecator is monitored. In particular, by checking the presence / absence of an occult blood portion, the present invention assists in early detection of colorectal cancer and allows a fecal occult blood test to be performed in a hygienic manner without burdening the user.
Owner:SETECH CO LTD

Full-automatic fecal occult blood analyzer

The invention relates to a full-automatic fecal occult blood analyzer, and belongs to measurement devices used for immunization test. The analyzer comprises a main case, an upper cover, a reaction disc component, a sample disc component, a reagent loading bracket, a probe component, a mechanical arm component and a base plate, wherein the probe component and the mechanical arm component are connected with the base plate respectively. The full-automatic fecal occult blood analyzer has the advantages that the full-automatic sample detection can be realized, the test velocity is fast, the possibility that a tester comes into contact with the sample is lowered, so that the environmental protection is facilitated and the hemoglobin concentration in excrement can be measured quantitatively.
Owner:DIRUI MEDICAL TECH CO LTD

Fecal occult blood testing device and method

A specimen testing device having a first panel including a first aperture for receiving a first specimen and a second aperture for receiving a second specimen; a second panel; a sheet disposed between the first and second panels for receiving at least the first specimen through the first aperture, wherein the sheet includes a test area having a reagent for possible reaction to the first specimen as part of a primary test procedure; and a removable tab at least partially aligned with the second aperture for receiving the second specimen, the removable tab accessible from an exterior of the device and available for use in a secondary test procedure. A method of testing for the presence of blood in fecal matter including primary and secondary testing of the fecal matter. A test kit including a specimen testing device and reagents for performing a primary test a secondary test on specimens.
Owner:IMMUNOSTICS

Sanitary and compact fecal occult blood collector

A biological sample collection and test kit and a method of using the kit are disclosed in the application. The kit includes a swab, having a sample collection portion, a cover for covering the sample collection portion of the swab for hygienic purpose. Also disclosed is a package for the swab and the cover.
Owner:ABBOTT RAPID DIAGNOSTICS INT UNLTD

Occult blood detection in biological samples by laser desorption and matrix-assisted laser desorption/ionization mass spectrometry for biomedical applications

Methods are described for detecting and quantifying occult blood in a biological sample using laser desorption mass spectrometry (LD MS). Biological samples that can be analyzed using various embodiments of the present invention include stool (fecal occult blood, FOB), and any bodily fluid including urine, cerebrospinal fluid and other bodily fluids. If the heme or heme metabolite is bound to protein, the sample is treated with acid before analysis to release the porphyrin. Some of the methods use LD MS with a time of flight analyzer (TOF) to detect and measure unbound heme, other hemoglobin metabolites and other molecules that have a porphyrin-based structure, e.g., bilirubin, biliverdin, protoporphyrin IX, and Zinc protoporphyrin in the biological sample. In other methods, matrix-assisted laser desorption / ionization mass spectrometry (MALDI MS) is used to detect and quantify the individual α- and β-polypeptide chains of hemoglobin.
Owner:THE JOHN HOPKINS UNIV SCHOOL OF MEDICINE

Device for fecal occult blood test

A devise for fecal occult blood test comprises a first and a second casings, a sampling portion extending from the first casing, a specimen processing portion, at least a testing portion and a packing cylindrical member. The packing cylindrical member is coupled between the first and second casings when unused and dismantled therefrom when used. After sampling via a specimen collecting portion of the sampling portion, the specimen collecting portion is drawn into the first casing to reduce the device size. The first and second casings are fixedly coupled together in a specimen processing position thereof to mix specimens with a liquid of the specimen processing portion into a testing liquid, and then in a specimen testing position thereof to disperse onto the testing portions for testing and directly display test results. The present invention advantages high accuracy, rather hygiene, significant size reduction, real-time testing-result display and convenient use.
Owner:TAICHUNG VETERANS GENERAL HOSPITAL

Fluid system of automatic fecal occult blood analyzer

The invention discloses a liquid-way system of a fully-automatic fecal occult blood analyzer, which is composed of an automatic sample adding module and a cleaning module, wherein the automatic sample adding module is used for adding samples and reagents; the cleaning module is used for cleaning sample needles, reagent needles and stirring rods; the automatic sample adding module is composed of asample injection pump, a sample needle, a reagent injection pump, a three-way solenoid valve, a reagent needle and a buffer solution bottle; and the cleaning module is composed of a cleaning injection pump, a three-way solenoid valve, a sample injection pump, a cleaning solution bucket, a cleaning pump, a two-way solenoid valve, a cleaning tank, a waste liquid pump and a waste liquid bucket. The invention has the beneficial effects that the injection rates of samples and reagents are controlled by the injection pumps, the quantitative accuracy is high, and the cleaning pump and the waste liquid pump are diaphragm pumps, thereby meeting the operating requirements and lowering the cost at the same time.
Owner:DIRUI MEDICAL TECH CO LTD

Enema for curing radioactivity rectitis

ActiveCN101254276AImprove lesionImprove radiation damageDigestive systemUnknown materialsSide effectBud
The invention belongs to the technology field of traditional Chinese medicine, in particular to an enema for the treatment of radioactive rectitis, which can solve the problem that the prior art has no ideal drug and effective method for the radioactive rectitis. The enema for the treatment of the radioactive rectitis is prepared by the raw materials with the following weight ratio of 3 to 6g of sanchi, 3 to 6g of catechu, 5 to 10g of donkey-hide glue, 10 to 30g of common bletilla pseudobulb, 15 to 45g of garden burnet root, 6 to 9g of rhubarb and 15 to 30g of hairyvein agrimonia herb and bud. The enema of the invention can significantly ease mucous bloody stool, diarrhea, abdominal pain, tenesmus, anal burning pain and bearing-down pain and other clinical symptoms, improve the positive of fecal occult blood test, the colonoscopy mucous membrane lesions and the radiation injuries and improve the quality of lives of the patients; and the enema has low recurrence rate, reliable efficacy, stable function, no toxicity or side effects, thus being the more satisfied drug for the treatment of the radioactive rectitis.
Owner:SHANXI ZHENDONG PHARMA

Colloid gold duplex test strip for detecting fecal occult blood and preparation method thereof

The invention relates to a colloid gold duplex test strip for detecting fecal occult blood and a preparation method thereof. The colloid gold duplex test strip is composed of a bottom lining, a sample pad, a marker pad, a coating film and bibulous paper, wherein the sample pad, the marker pad, the coating film and the bibulous paper are sequentially adhered to the bottom lining in a lap joint mode. The marker pad comprises a colloid gold marked mouse against human Hb monoclonal antibody Hb1 and a mouse against human Tf monoclonal antibody Tf1, the concentration of the mouse against human Hb monoclonal antibody Hb1 is 5-20 Mu g / mL, and the concentration of the mouse against human Tf monoclonal antibody Tf1 is 5-20 Mu g / mL. According to the colloid gold duplex test strip, hemoglobin and transferrin in faeces are detected synchronously, the specificity is high, the sensitivity is high (the detection limit of Hb is 200 ng / ml, and the detection limit of Tf is 40 ng / ml respectively), the positive detection rate of the digestive tract hemorrhagic disease is improved remarkably, the asymptomatic, slight and continuous alimentary tract hemorrhage which cannot be seen by naked eyes and a microscope can be accurately detected, and the colloid gold duplex test strip can avoid the interference of medicine, such as animal blood and so on.
Owner:XIAMEN INST OF RARE EARTH MATERIALS

Fecal occult blood detection kit and preparation method

The invention discloses a fecal occult blood detection kit, which comprises a fecal occult blood detection test paper strip or a test paper card, a sample processing pipe or a feces acquisition mixer and a sampling rod, the test paper strip or the test paper card comprises a detection zone (T) coated with anti-Hb 1 monoclonal antibody and a quality control zone (C) coated with a goat anti mouse polyclonal antibody and a colloidal gold coated with anti-Hb 2 monoclonal antibody. The preparation method of the kit comprises the following steps: preparing a treating liquid, preparing the kit, preparing a colloidal gold compound, spraying metal, cutting, assembling, cutting, packaging and the like. The fecal occult blood detection kit has the advantages of good specificity, high sensitivity, rapid and simple detection, and has no limitation by food and medicine.
Owner:安徽深蓝医疗科技股份有限公司

Fecal occult blood latex-enhanced immunoturbidimetric kit

The invention discloses a fecal occult blood latex enhanced immunoturbidimetric kit comprising a R1 reagent, a R2 reagent and a human hemoglobin calibrator; the R1 reagent comprises a glycine buffer,PEG6000 and ProClin-300; the R2 reagent comprises a glycine buffer, rabbit anti-human hemoglobin-coated latex microspheres, bovine serum albumin, Tween-20, trehalose, ProClin-300; the latex microspheres in the reagent R2 have a particle size of 60 to 220 nm, and a hemoglobin antibody is rabbit anti-human hemoglobin polyclonal antibody, and is linked to the polystyrene latex microspheres by covalent coupling. Latex enhanced immunoturbidimetric detection results objectively reflect the amount of bleeding, the fecal occult blood latex enhanced immunoturbidimetric kit facilitates observing of changes in conditions of diseases; due to a full automatic operation mode, the detection process is more convenient and quick, and the fecal occult blood latex enhanced immunoturbidimetric kit can test inbatches, and is more suitable for screening experiments of large-scale populations.
Owner:天津市协和医药科技集团有限公司

Automatic fecal occult blood detector

The present invention discloses an automatic fecal occult blood detector for detecting a sample kit, comprising: a feed passage and a discharging passage which are provided in parallel and convey a sample kit separately; a transfer platform configured between the feed passage and the discharging passage; a push rod configured to push the sample kit on the feed passage onto the discharging passage through the transfer platform; and an image capturing device provided on one side of the discharging passage to acquire the color band information presented on a test strip. In the present invention, the parallel arrangement of the feed passage and the discharging passage shortens the whole length of the automatic detector, meeting the requirement that the color band information of the test strip is automatically acquired after the sample kit is left in the device a certain time.
Owner:W H P M BIORES & TECH

Fecal occult blood detection kit

ActiveCN110441515ATaking storage stability into considerationImprove HB stabilityBiological testingArginineGrossularine-1
The invention discloses a fecal occult blood detection kit. The fecal occult blood detection kit comprises a sample diluent, a calibrator, a quality control material, a reagent 1 and a reagent 2; thereagent 1 is a reaction buffer solution; the reagent 2 is a hemoglobin antibody sensitized latex solution; and 1 g / L tris(2-carboxyethyl)phosphine, 1 to 2 g / L glutathione, 1 to 2 g / L glutamic acid, 0.1 to 0.2 g / L arginine, 0.1 to 0.2 g / L cysteine and 1 to 2 g / L ethylene diamine tetraacetic acid are added into the sample diluent, a background buffer solution of the calibrator, a background buffer solution of the quality control material, the reagent 1 and the reagent 2. According to the fecal occult blood detection kit, the stability in the storage and detection reaction process of HB can be improved; various reagent and raw materials are simple and easily obtained; and the fecal occult blood detection kit is convenient to prepare and wide in application range.
Owner:BYRON DIAGNOSTICS SHANGHAI

Integrating spherical optical system of automatic fecal occult blood analyzer

The invention relates to an integrating spherical optical system of an automatic fecal occult blood analyzer, which belongs to the optical system of the fecal occult blood analyzer, and comprises an illumination unit, a sample unit, a signal collecting unit and a signal processing unit, which are sequentially connected with each other, wherein an integrating sphere is added in the optical system to realize the simultaneous measurement of transmitted light and scattered light, the chromatic absorption problem is solved through a ratio method, and the light intensity fluctuation of a light source is corrected, so the sensitivity can be improved. The integrating spherical optical system can correct the interference of the chroma / or light absorption substances and can compensate the fluctuation of the light intensity, so long-term stable correction can be provided, and the integrating spherical optical system has strong practicability.
Owner:DIRUI MEDICAL TECH CO LTD

Rapid fecal occult blood double detection test strip and preparation method thereof

The invention discloses a rapid fecal occult blood dual detection test strip and a preparation method thereof, and relates to the technical field of detection of fecal occult blood markers transferrin and hemoglobin. The test strip is composed of a liner, a sample pad connected in sequence on the liner, a double detection gold standard binding pad, a coating film, and a water-absorbing pad. The double detection gold standard binding pad is sprayed with transferrin-labeled antibody and hemoglobin gold For the target glass fiber membrane, there are invisible detection lines T1 and T2 printed with transferrin antibody and hemoglobin antibody on the coated membrane, and invisible control line C printed with goat anti-mouse IgG. The invention is based on the colloidal gold immunochromatography technology for dual detection of transferrin and hemoglobin. One test paper can simultaneously detect two indicators of transferrin and hemoglobin, and has the characteristics of high sensitivity, short reaction time, convenience and ease of use.
Owner:安徽深蓝医疗科技股份有限公司

Devices and methods for reading and interpreting guaiac-based occult blood tests

A medical analysis system for reading and interpreting an occult blood test (OBT) device is provided. The instant system comprises an image sensor for capturing an image of the entire test area of the fecal occult blood test (FOBT) device and for converting the image into a digital data. The system further comprises a data processor conventionally coupled to the image sensor. The data processor compares the digital data with pre-determined threshold conditions of a positive FOBT by utilizing a spectrographic and morphologic image analysis algorithm and determines a presence of the occult blood in the sample. A hue angle analysis for data processing may be used. A method of performing FOBT on a sample is also provided.
Owner:BECKMAN COULTER INC

A household networked system for detecting occult blood in feces and urine

The invention provides a household networked system for detecting occult blood in feces and urine, and particularly provides a device for detecting fecal occult blood. The device comprises a detecting module and a result outputting module. The detecting module is used for detecting occult blood and sending a detection result to the result outputting module. The detection result is displayed in the result outputting module. The invention also provides a close stool comprising the device for detecting the fecal occult blood. By utilization of a technical scheme, detection is free of sampling, simple in operation, and free of operation by professional operators. The system, the device and the close stool are suitable for household use. The device is high in sensitivity, can be networked with a computer and a mobile phone data processing terminal so as to achieve data processing and / or sharing, can compare detection data with data in a database, and gives a reasonable suggest.
Owner:丰能医药科技(上海)有限责任公司

Method of detecting colon cancer marker

It is intended to provide a non-invasive and convenient method of detecting a tumor marker for diagnosing colon cancer which is superior in sensitivity and specificity to the existing fecal occult blood test. More specifically speaking, a method of detecting a tumor marker for diagnosing colon cancer which comprises collecting biological sample which is immediately frozen using liquid nitrogen in some cases, homogenizing the sample in the presence of an inhibitor of an RNA digesting enzyme to give a suspension, extracting RNA from the obtained suspension, subjecting the extracted RNA to reverse transcription to give cDNA, amplifying the obtained cDNA and then detecting the thus amplified cDNA. This method is characterized by involving no procedure of separating cell components from the biological sample.
Owner:NATIONAL UNIVERSITY +1

Sample automatic feeder of full automatic fecal occult blood analyzer

The invention discloses a sample automatic feeder of a full automatic fecal occult blood analyzer. The sample automatic feeder consists of a driving mechanism, a bar code scanning mechanism and a retaining tube mechanism, all of which are arranged on a base plate, wherein the driving mechanism consists of a motor, a synchronous belt and a sample tube frame, a transmission shaft of the motor is connected with a rotary shaft of the sample tube frame through the synchronous belt, the motor drives the sample tube frame to rotate through the synchronous belt, the bar code scanning mechanism consists of a bar code scanner and a support, the support is arranged on the base plate, the retaining tube mechanism consists of a retaining rod, a pull rod, an electromagnet and a tension spring, the retaining rod and the pull rod are connected by a pull rod shaft, and the pull rod drives the retaining rod to rotate through the pull rod shaft. The sample automatic feeder of the full automatic fecal occult blood analyzer, disclosed by the invention, has the beneficial effects of simple structure, convenience for using, stability in mechanical operation and lower installation use cost.
Owner:DIRUI MEDICAL TECH CO LTD

Method and kit for detecting an analyte in a sample

The present invention provides devices, methods, and kits for the collection of a solid or semi-solid sample and analysis for the presence, absence, or quantity of an analyte. The invention provides an assay device having a housing containing a test element, a results window, and a docking area for receiving and engaging a sample collection slide. The docking area has a sample receiving orifice with one or more fluid transfer structures. In one embodiment the collection slide and device can be used to detect the presence of fecal occult blood (human hemoglobin) in a stool sample. Many other embodiments are described herein.
Owner:LIAO FEIER +1
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products