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5 results about "Viral Oncogene" patented technology
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Cancer-causing genes encoded in viral genomes. Usually denoted v-onc.
Novel compounds as KRAS inhibitors and uses thereof
Described herein are Kirsten rat sarcoma viral oncogene homologue (KRAS) inhibitors and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for the treatment of a KRAS associated disease or disorder.
Owner:INSILICO MEDICINE IP LTD
Methods of using Anti-EGF antibodies to augment the activity of BRAF and KRAS inhibitors
Embodiments of the present disclosure are directed to methods for treating and preventing disease conditions, such as cancer, particularly in those individuals who have developed a resistance to, or who are not responsive to, cancer therapies involving v-Raf murine sarcoma viral oncogene homolog B1 (BRAF) or Kirsten rat sarcoma oncogene homolog (KRAS) inhibitors.
Owner:IN3BIO LTD
T cell receptors recognizing HLA-CW8 restricted mutated KRAS
Disclosed is an isolated or purified T cell receptor (TCR) having antigenic specificity for mutated Kirsten rat sarcoma viral oncogene homolog (KRAS) presented in the context of an HLA-Cw*0802 molecule. Related polypeptides and proteins, as well as related nucleic acids, recombinant expression vectors, host cells, populations of cells, and pharmaceutical compositions are also provided. Also disclosed are methods of detecting the presence of cancer in a mammal and methods of treating or preventing cancer in a mammal.
Owner:THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY DEPARTMENT OF HEALTH & HUMAN SERVICES
