45 results about "Tumor Weight" patented technology

The invention provides the application of a radiotherapy sensitizer of the lychee grass water extract. The invention uses the lychee grass water extract as a radiotherapy sensitizer to inhibit the growth of tumor tissues of colorectal cancer CT26 cell line tumor-bearing mice. The use of lychee grass water extract as a radiotherapy sensitizer significantly improved the general activity of CT26 cell transplanted tumor model mice, inhibited the growth of tumor tissue, reduced tumor weight, and had a significant inhibitory effect on the growth and proliferation of colorectal cancer. The mechanism of action is related to the down-regulation of the expression of VEGF and Survivin in tumor tissues of mice transplanted with CT26 cells. The invention further expands the application of the water extract of lychee grass, clarifies the effect of the radiotherapy sensitizer of the water extract of lychee grass on inhibiting colorectal cancer, and provides an effective means for clinical tumor treatment by adopting the method of assisting radiotherapy with traditional Chinese medicine.

The present invention discloses thymopentin modified by heterocyclic carboxylic acid represented by general formula I, wherein RCO is 1,2,3,4-tetrahydro-β-carboline-3-formyl, β-carboline ‑3‑formyl, 1,2,3,4‑tetrahydroisoquinoline‑3‑formyl, isoquinoline‑3‑formyl, 1‑methyl‑1,2,3,4‑tetrahydro‑ β-carboline-3-formyl, 1-methyl-β-carboline-3-formyl and 4,5,6,7-tetrahydro-3H-imidazo[4,5-C]pyridine-6- Formyl, disclosed their preparation method, disclosed their anti-tumor cell proliferation activity in vitro, further disclosed their activity of inhibiting tumor weight gain in S180 tumor mice, and clarified their application in the preparation of anti-tumor drugs. RCO‑Arg‑Lys‑Asp‑Val‑Tyr I.

The invention relates to application of spirulina platensis polysaccharide, which is applied to preparing preparations for restraining tumor growth, preparations with antioxygenation functions to cells and nuclear factor kappa (NF-KB) immune preparations. A spirulina platensis washing gavage administration method has restraining functions on S180 tumors. After administration, spirulina platensis water is used for extracting washing polysaccharide of 100mg / kg, and T / C% is 58.95%. Compared with a control group, the weight of a tumor is obviously different (rho (0.05). Spleen cells of a mice immune organ are used for multiplication experiments of immune cells. Results show that 40, 200 and 1000 ug / ml of spirulina platensis polysaccharide all have functions of promoting multiplication of spleen cells, and when the T / C% is respectively 148.96%, 166.89% and 182.99%, and the T / C% is obviously different from a medicine-free group (rho (0.05). 0.2mol / l of spirulina platensis, 8ug / ml of Nacl elution polysaccharide and 40ug / ml of the Nacl elution polysaccharide have effects on promoting multiplication of spleen cells, and when the T / C% is respectively 19.88% and 202.81%, the T / C% is obviously different from the medicine-free group (rho (0.05).