Kit for early stage colorectal cancer auxiliary diagnosis and use method and detection system thereof
A technology for auxiliary diagnosis of colorectal cancer, applied in the field of biotechnology and diagnostic research, can solve the problems affecting the sensitivity of tumor detection and missed diagnosis, and achieve the effect of high acceptance, high specificity and sensitivity
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Image
Examples
Embodiment Construction
[0045] Due to the growth characteristics of colorectal cancer, it first extends to the intestinal cavity. During its growth, including precancerous adenomas or early stages of cancer, a large number of tumor cells are constantly shed by metabolism and enter the excretory system to be excreted together with feces. Among these cells Contains genes closely related to tumorigenesis, reflecting the process of tumor formation, and by detecting these gene markers in feces, the presence of tumors on the intestinal wall can be found. Because these genes exist from the early stage of tumor generation, they can reflect the earliest process of tumor.
[0046] The gene targets used in the present invention are KRAS (v-Ki-ras2, Kirsten rat sarcoma viraloncogene homolog) gene mutation, BMP3 (Bone Morphogenetic Protein 3) and NDRG4 (N-MycDownstream-Regulated Gene 4) gene methylation. KRAS gene mutations are present in more than 35% of colorectal cancer cells, and the seven mutations in exon 2...
PUM
Property | Measurement | Unit |
---|---|---|
Sensitivity | aaaaa | aaaaa |
diameter | aaaaa | aaaaa |
Abstract
Description
Claims
Application Information
- R&D Engineer
- R&D Manager
- IP Professional
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com