8 results about "Pyloric orifice" patented technology

In some examples, a gastroretentive system includes a dissolvable outer capsule, a body disposed within the outer capsule, at least one expandable and collapsible member coupled to the body and configured to be disposed within the outer capsule in a collapsed condition when the outer capsule is present and to transition to an expanded condition without the outer capsule, the expanded condition being too large to pass through a human pylorus, wherein at least one of the body and the at least one expandable and collapsible member includes a drug product.

The utility model discloses a kind of gastric cavity plugging catheters of gastrostomy in the medical instrument technical field, the device increases plugging balloon and sealing clamping piece, can be held by inside and outside, hold stomach wall and skin to position the device, while plugging balloon seals and isolates the puncture of stomach wall inside gastric cavity, effectively avoid gastric juice to flow out, avoid gastric juice to overflow along the puncture and cause skin burning;Positioning baffle is also increased, can be unfolded inside duodenum, positioning baffle can position nutrition tube, avoid nutrition tube to slide and separate, can also effectively block pylorus, effectively avoid enteric digestive juice to enter stomach, and do not hinder gastric juice to flow into intestine normally, and by pressure relief port and pressure relief pipe, stomach is conveniently decompressed, effectively avoid that pressure is too high and nutrition liquid is refluxed to esophagus.

A system for a bypass-like, transduodenal passage of stomach contents, comprising: a transduodenal bypass unit (BE), itself comprising a transduodenal assembly (TDG) having a tubular film (7) for the passage of stomach contents into the jejunum, and also comprising a transpyloric assembly (TPG) having a hose-like or tubular shaft component (2); a transesophageal positioning unit (PE) having a tubular shaft component (9), the outer diameter of said shaft component being smaller, at least in a distal region, than the inner diameter of the shaft component (2); and an extracorporeally controllable coupling device (KE) which selectively fixates the shaft component (2) to the shaft component (9) for coupling purposes or releases the same for decoupling purposes.

This invention relates to the field of pharmaceutical formulation technology, specifically to a sustained-release formulation of rifabutin, and more specifically, to a sustained-release rifabutin formulation composition for treating Helicobacter pylori infection. The key technical point of this invention is that it uses a novel antibiotic for treating Helicobacter pylori infection as the active ingredient, supplemented with specific inactive ingredients, including a hydrophilic gel-type matrix sustained-release material, a swelling agent, a buoyancy aid, and a lubricant. Through the synergistic effect of the hydrophilic gel-type matrix sustained-release material, the swelling agent, and the buoyancy aid, the composition can rapidly swell in gastric juice and maintain a floating state, thereby significantly prolonging the residence time of the formulation in the stomach and upper small intestine. This invention solves the technical problem of conventional formulations having a short residence time in the stomach and requiring frequent administration to maintain an effective antibacterial concentration, achieving the goal of effectively eradicating Helicobacter pylori by reducing the number of doses while maintaining an effective concentration at the site of infection for a longer period.

This invention provides a pyloric myotomy device capable of performing opening and cutting operations with a single instrument, comprising: an operating rod having a fixed jaw at one end and a fixed handle at the other end; a movable jaw hinged to the fixed jaw; a movable handle rotatably connected to the fixed handle and connected to the movable jaw via a connecting assembly for controlling the opening and closing of the movable jaw; and an operating sleeve fixedly fitted on the outer surface of the operating rod and positioned close to the fixed handle. The operating rod has a receiving groove extending along its length, and a blade is disposed within the receiving groove. The operating sleeve has an operating handle connected to the other end of the blade for controlling the blade to extend or retract from the opening. The operating handle has a limiting element that prevents the movable handle from rotating, so that the movable handle cannot rotate when the blade extends from the opening under the control of the operating handle, thereby limiting the opening of the movable jaw.

The application discloses a nasointestinal tube catheterization position recognition and catheterization state guiding method and system, acquires an endoscope video stream in a catheterization process, recognizes an anatomic position of a front end of a nasointestinal tube in a digestive tract after image preprocessing, recognizes a tube body and a scale mark of the nasointestinal tube, calculates a catheter use length from a cardia to a pylorus according to a cardia position, a pylorus position and corresponding scales, and generates a gastric catheterization state judgment result in combination with a cardia-to-pylorus spatial distance; after the front end of the nasointestinal tube passes through the pylorus, a reference scale at the pylorus is recorded, a pylorus passing length is generated according to a difference between a front end corresponding scale and the reference scale, and an intestinal tract part auxiliary judgment result is output. The system superimposes and displays position recognition, gastric catheterization state judgment and intestinal tract depth judgment results, and provides guidance for a nasointestinal tube catheterization process.

The utility model relates to medical instrument technical field discloses a long -acting gastric retention drug delivery device, can enter the stomach through the oral self -ingestion mode, further realizes size change through the unfolding of elastic component, and the mechanical strength of elastic component is strengthened through water -induced hard polymer, avoids being extruded deformation and is emptied through the stomach pylorus. The device includes drug loading component, elastic component and connecting component, and the drug loading component includes multiple drug loading pieces, and the drug loading piece all has the drug loading cavity. The elastic component includes multiple elastic pieces, and the first end of multiple elastic pieces is connected with each other to make the elastic component present star -like under the unfolded state. The outer layer of elastic component is covered with reinforcing film, and the reinforcing film is formed by water -induced hard polymer solidification and can gradually transform from flexible to rigid under the aqueous environment. The connecting component includes multiple connecting pieces, and the second end of an elastic piece is connected with a drug loading piece through a connecting piece, and the connecting piece is decomposed under the preset condition, so that the drug loading piece and elastic component are separated and are discharged outside non -invasively.

This invention discloses a traditional Chinese medicine composition for the prevention and / or treatment of gastric ulcers and / or their complications. By weight, the composition comprises: 2-6 parts of Atractylodes lancea, 2-6 parts of Poria cocos, 1-4 parts of Magnolia officinalis, 2-6 parts of Aucklandia lappa, 1-4 parts of Lindera strychnifolia, 1-4 parts of Cyperus rotundus, 1-4 parts of Alpinia officinarum, 1-4 parts of Amomum villosum, 1-4 parts of Coix lacryma-jobi, 1-4 parts of Citrus reticulata peel, 1-4 parts of Citrus medica, 1-4 parts of Crataegus pinnatifida, 1-4 parts of Massa fermentata, 1-4 parts of Hordeum vulgare, 1-4 parts of Gallus gallus domesticus gizzard lining, 1-4 parts of Bletilla striata, 2-6 parts of Paeonia lactiflora, 2-6 parts of Corydalis yanhusuo, 1-4 parts of Cinnamomum cassia, and 1-4 parts of Piper longum. The complications are selected from one or more of the following: pain, inflammation, and delayed gastric emptying. This traditional Chinese medicine composition is safe, effective, and has a simple and efficient preparation method with controllable quality. It exhibits significant anti-inflammatory, analgesic, and gastric motility-promoting effects, and can reduce the colonization of Helicobacter pylori in the stomach. It also has significant therapeutic effects on gastric ulcers induced by different factors (Helicobacter pylori infection, pyloric ligation, and nonsteroidal anti-inflammatory drugs).