38 results about "Pyloric orifice" patented technology

An occlusion device or plug having a proximal plug section and a distal plug section. The plug sections may each be shifted between an unexpanded configuration and an expanded configuration at the deployment site to occlude the deployment site. A tubular member such as a silicone tube may be used to form an occlusion device or plug shiftable or expandable into a desired configuration. An intermediate section between a proximal plug section and a distal plug section may be configured to be manipulated at least to shift at least one of the plug sections from an expanded configuration to an unexpanded configuration. A pair of stents may be coupled together via an intermediate section in such manner such that manipulation of the intermediate section causes at least one of the stents to shift from an expanded configuration to an unexpanded configuration.

In some examples, a gastroretentive system includes a dissolvable outer capsule, a body disposed within the outer capsule, at least one expandable and collapsible member coupled to the body and configured to be disposed within the outer capsule in a collapsed condition when the outer capsule is present and to transition to an expanded condition without the outer capsule, the expanded condition being too large to pass through a human pylorus, wherein at least one of the body and the at least one expandable and collapsible member includes a drug product.

The utility model relates to an automatic gastric emptying monitoring device of a bionic digestive system, which comprises a rotating disc, the rotating disc is rotationally arranged, the included angle between the center line of the rotating disc and the vertical direction is not zero, and a bionic stomach component is arranged on the rotating disc; the weighing assembly comprises a first container, a measuring instrument and a second container, the measuring instrument and the second container are contained in the first container, the measuring instrument is used for weighing the second container, the second container is communicated with the pylorus of the bionic stomach assembly, the first container comprises a container body and a rotating shaft, the container body is provided with a round hole, and the rotating shaft penetrates through the round hole and is rotationally connected with the container body; the rotating shaft is connected with the rotating disc and extends in the horizontal direction. According to the utility model, the weighing assembly is rotatably arranged on the turntable through the rotating shaft and the round hole, and the weighing assembly is adaptively adjusted to be in a horizontal state by utilizing the gravity of the weighing assembly, so that real-time online monitoring of gastric emptying data is realized, automatic sampling of the bionic gastric assembly is also realized, and the difficulty of sampling work is greatly reduced.

The utility model discloses a kind of gastric cavity plugging catheters of gastrostomy in the medical instrument technical field, the device increases plugging balloon and sealing clamping piece, can be held by inside and outside, hold stomach wall and skin to position the device, while plugging balloon seals and isolates the puncture of stomach wall inside gastric cavity, effectively avoid gastric juice to flow out, avoid gastric juice to overflow along the puncture and cause skin burning;Positioning baffle is also increased, can be unfolded inside duodenum, positioning baffle can position nutrition tube, avoid nutrition tube to slide and separate, can also effectively block pylorus, effectively avoid enteric digestive juice to enter stomach, and do not hinder gastric juice to flow into intestine normally, and by pressure relief port and pressure relief pipe, stomach is conveniently decompressed, effectively avoid that pressure is too high and nutrition liquid is refluxed to esophagus.

The utility model discloses a multifunctional bedside nasojejunum nutrition tube placement training device which comprises a head and neck bionic block, a nasopharyngeal cavity channel is arranged in the head and neck bionic block; the pleuroperitoneal cavity frame comprises a hard simulation frame and bionic skin covering the hard simulation frame. Wherein the head and neck bionic block and the pleuroperitoneal cavity frame are integrally formed or detachably connected. A bionic esophagus, a bionic stomach, a bionic duodenum and a part of bionic jejunum which are sequentially connected are arranged in the pleuroperitoneal cavity frame, and a bionic cardia and a bionic pylorus are arranged at the head end and the tail end of the bionic stomach respectively. A bionic inferior vena cava, a bionic abdominal aorta, a bionic mesenteric superior vein and a bionic mesenteric superior artery are further arranged in the pleuroperitoneal cavity frame; the bionic inferior vena cava and the bionic abdominal aorta are arranged on the rear sides of the bionic stomach and the bionic duodenum, the bottom ends are closed, and the head ends penetrate out of the bionic skin; the bottom ends of the bionic superior mesenteric vein and the bionic superior mesenteric artery are closed, and the head ends of the bionic superior mesenteric vein and the bionic superior mesenteric artery partially wrap the bionic duodenum and then penetrate out of the bionic skin.

A system for a bypass-like, transduodenal passage of stomach contents, comprising: a transduodenal bypass unit (BE), itself comprising a transduodenal assembly (TDG) having a tubular film (7) for the passage of stomach contents into the jejunum, and also comprising a transpyloric assembly (TPG) having a hose-like or tubular shaft component (2); a transesophageal positioning unit (PE) having a tubular shaft component (9), the outer diameter of said shaft component being smaller, at least in a distal region, than the inner diameter of the shaft component (2); and an extracorporeally controllable coupling device (KE) which selectively fixates the shaft component (2) to the shaft component (9) for coupling purposes or releases the same for decoupling purposes.

This invention relates to the field of pharmaceutical formulation technology, specifically to a sustained-release formulation of rifabutin, and more specifically, to a sustained-release rifabutin formulation composition for treating Helicobacter pylori infection. The key technical point of this invention is that it uses a novel antibiotic for treating Helicobacter pylori infection as the active ingredient, supplemented with specific inactive ingredients, including a hydrophilic gel-type matrix sustained-release material, a swelling agent, a buoyancy aid, and a lubricant. Through the synergistic effect of the hydrophilic gel-type matrix sustained-release material, the swelling agent, and the buoyancy aid, the composition can rapidly swell in gastric juice and maintain a floating state, thereby significantly prolonging the residence time of the formulation in the stomach and upper small intestine. This invention solves the technical problem of conventional formulations having a short residence time in the stomach and requiring frequent administration to maintain an effective antibacterial concentration, achieving the goal of effectively eradicating Helicobacter pylori by reducing the number of doses while maintaining an effective concentration at the site of infection for a longer period.

The gastric bypass device includes an obstruction device adapted to be positioned against the patient's pyloric sphincter and a liner extending distally from the obstruction device. A tether extends from the obstruction device. A dynamic leash can be secured to the obstruction device and can cooperate with the tether to help hold the obstruction device in place.

The invention relates to a Tibetan medicine compound preparation for relieving stomach discomfort and protecting gastric mucosa. The Tibetan medicine compound preparation is prepared from 11 medicinal materials including gypsum rubrum (prepared), safflower carthamus, liquorice and the like through a special process. The core innovation is as follows: gypsum rubrum is processed by co-melting borax, potassium nitrate and aconite, a high-dissolution-rate calcium-boron compound is generated, and the toxicity is reduced; the highland barley wine and the yellow milk cooperate to form a gastric mucosa protective film. The medicinal materials are subjected to dynamic three-stage ultrasonic extraction (300 W to 200 W to 200 W) to realize graded dissolution of fat-soluble and heat-sensitive components, and the purity of the effective components reaches 98% in combination with a membrane filtration system (5 mu m to 0.45 mu m to 0.2 mu m). According to the compound, three-axis synergy of acid-relieving and pain-relieving (the pH value is increased to 3.5-4.0 in 30 minutes), blood-activating and film-protecting (the DPPH clearance rate is 89%) and qi-regulating and distention-eliminating (the helicobacter pylori MIC value is 0.5 mg / mL) is adopted, and nitrogen-filled packaging (the stability is 18 months) and palatability optimization (the compliance is 92%) are adopted as auxiliary materials. The acute toxicity LD50 is greater than 5g / kg, the long-term toxicity does not cause liver and kidney injury, the bottleneck of side effects of western medicines is broken through, and the traditional Chinese medicine is suitable for health care and adjuvant therapy of stomachache, sour regurgitation and other symptoms.

The invention discloses a dynamic bionic stomach digestion model and application thereof in micro-plastic detection.The dynamic bionic stomach digestion model comprises a box body, a fixing plate, an artificial stomach model, rolling wheels, a pylorus squeezing plate, a pH meter, a heating mechanism, a gastric acid solution cavity, a gastric juice solution cavity, a peristaltic pump and a micro-dialysis probe, and the rolling wheels are rotationally arranged on the fixing plate and located on the periphery of the outer surface of the artificial stomach model; the pylorus extrusion plate is movably arranged on the fixing plate and located on the outer side of the lower end of the artificial stomach model so as to extrude the lower end of the artificial stomach model, and the gastric acid solution cavity and the gastric juice solution cavity are communicated with the upper end of the artificial stomach model through the peristaltic pump. The method comprises the following steps: adding an aged biofilm-loaded micro-plastic sample or a micro-plastic sample loaded with heavy metal and the like and agar balls into an artificial stomach model, digesting in the artificial stomach model, detecting discharged liquid, solids and the like after digestion is completed, detecting the concentration change of digestive juice, micro-plastic particles and micro-plastic precipitates on agar ball particles, and determining the concentration change of the micro-plastic precipitates on the micro-plastic particles and the agar balls. Product identification and the like.

This invention provides a pyloric myotomy device capable of performing opening and cutting operations with a single instrument, comprising: an operating rod having a fixed jaw at one end and a fixed handle at the other end; a movable jaw hinged to the fixed jaw; a movable handle rotatably connected to the fixed handle and connected to the movable jaw via a connecting assembly for controlling the opening and closing of the movable jaw; and an operating sleeve fixedly fitted on the outer surface of the operating rod and positioned close to the fixed handle. The operating rod has a receiving groove extending along its length, and a blade is disposed within the receiving groove. The operating sleeve has an operating handle connected to the other end of the blade for controlling the blade to extend or retract from the opening. The operating handle has a limiting element that prevents the movable handle from rotating, so that the movable handle cannot rotate when the blade extends from the opening under the control of the operating handle, thereby limiting the opening of the movable jaw.

The present application relates to the field of intelligent medical treatment and artificial intelligence, and discloses a preoperative precise evaluation system for gastric antrum cancer with pyloric obstruction based on AI image recognition, which comprises: a data acquisition and preprocessing module, which acquires structured clinical data and multi-modal image data of a patient and performs preprocessing; a lesion identification and segmentation module, which performs lesion identification and segmentation processing on the preprocessed image data by using an improved nnU-Net framework; a feature extraction and screening module, which extracts image features from the segmentation result and screens out features related to clinical indicators; a multi-modal feature fusion module, which performs feature fusion on the screened image features and the preprocessed structured clinical data; a multi-task risk evaluation module, which establishes a multi-parameter risk prediction model by using a semi-structured distribution regression method and outputs multi-task prediction results; and an evaluation report generation module, which generates a structured evaluation report. The present application realizes intelligent and precise preoperative evaluation and postoperative risk prediction for gastric antrum cancer patients.

The invention discloses a stomach pylorus dilatation balloon pipeline, and relates to the technical field of medical instruments, the stomach pylorus dilatation balloon pipeline comprises a pylorus balloon and a small intestine balloon, a membrane tube is communicated between the pylorus balloon and the small intestine balloon, the pylorus balloon comprises a dilatation balloon and a functional layer, the functional layer covers the outer side of the dilatation balloon, and the membrane tube is communicated with the membrane tube. The two ends of the functional layer are fixed to the upper side and the lower side of the inner side of the dilation balloon, a medicine storage ring is arranged in the functional layer, an outer side film of the functional layer is folded inwards to form the medicine storage ring, the medicine storage ring is gradually opened along with dilation of the dilation balloon, the middle portion of the outer side of the dilation balloon is concaved inwards, and the medicine storage ring is arranged in the middle of the dilation balloon. And the upper part and the lower part of the outer side of the expansion balloon protrude outwards.

The utility model belongs to the field of medical instruments, and relates to a nasointestinal tube convenient to place. Comprising a bendable catheter, the front end of the catheter is provided with an opening, the front end opening and the side wall of the catheter are coated with a soluble sol layer, the rear end of the catheter is communicated with a main cavity and a side cavity, a guide wire is arranged in the catheter, the rear end of the guide wire extends out of the catheter and the main cavity and is connected with a guide wire fixator, and the front end of the guide wire is connected with a connecting pipe thicker than the guide wire. And fluff is connected to the circumferential wall of the connecting pipe. The front end of the connecting pipe is further connected with a metal ball. After the nasointestinal tube is placed into the stomach, under the combined action of gastrointestinal motility and the special structure of the front end of the nasointestinal tube, the front end of the nasointestinal tube is automatically placed into the intestinal tract through the pylorus, the success rate of tube placement is improved, and a large amount of tube placement time of medical staff is saved.

This application relates to a composition for preventing, improving, or treating gastrointestinal diseases comprising a strain of the genus Corynebacterium, a culture thereof, and threonine. Since the composition according to this application has been confirmed to have excellent anti-Helicobacter pylori efficacy in cell experiments, efficacy in improving gastrointestinal diseases in animal experiments, and efficacy in the synthesis of gastric mucus, the composition may be used as a pharmaceutical composition for preventing or treating gastrointestinal diseases, as a feed for preventing or improving gastric ulcers, or as a feed composition.

The utility model relates to the technical field of in-vitro digestive systems, and aims to solve the technical problem that a pylorus structure is not simulated. In order to solve the technical problem, the utility model provides a bionic pylorus structure, a pylorus contraction structure and a bionic system. The device comprises a flexible main body with a tubular structure, the plurality of pyloric sphincter bionic pieces are uniformly distributed on the inner wall of the flexible main body along the circumferential direction; the pyloric sphincter bionic part is formed by bulging from the inner wall of the flexible main body to the center; the hollow structure is enlarged and shrunk; in the axis direction of the flexible main body, the bulging size of the pyloric sphincter bionic piece is gradually increased and then reduced; a gap is formed between the free ends of every two adjacent pyloric sphincter bionic pieces, so that a multi-awn-star-shaped channel is formed in the center of the flexible main body to simulate the pyloric sphincter; the pylorus contraction structure drives the multiple pylorus sphincter bionic parts to relax and contract, and the diameter of the channel and the width and length of the gap are changed. The device can simulate the pylorus structure, and the test accuracy is improved.

The invention relates to a jejunum tube indwelling method, which adopts a sphere with a line A and a line B. One end of the line A is located at the sphere, the other end of the line A is a first free end, one end of the line B is located at the sphere, and the other end of the line B is a second free end. The ball moves downwards to the stomach and enters the duodenum through the pylorus, and the first free end and the second free end are located outside the human body and dragged by an operator; 2, the jejunum tube enters the stomach and the duodenum through the A line serving as a lead and reaches the ball, the B line is pulled, so that the A line is moved out of the jejunum tube, and the ball and the B line are moved out of the duodenum, the stomach and the esophagus. After the technical scheme is adopted, the jejunum tube can be quickly fed into the jejunum part through the duodenum, the tube indwelling success rate and efficiency are improved, and the jejunum tube indwelling device has the advantage of being easy to operate.

The utility model relates to the technical field of intestinal obstruction catheters, and discloses an intestinal obstruction catheter convenient to place, which comprises a catheter main body, a side hole is arranged on the front side of the end face of one side of the catheter main body, a front guide is fixedly arranged on the front end face of the catheter main body, and a traction mechanism is arranged on the front side of the front guide. A fixing mechanism is arranged on the rear side of the pipe body, the traction mechanism comprises a fixing ring, a soft sleeve and a sliding block, a threaded column is fixedly arranged on the end face of the side, close to the fixing ring, of the soft sleeve, a traction ring is fixedly arranged on the inner wall of the side, away from the fixing ring, of the soft sleeve, and the fixing mechanism comprises a flitch and an elastic rope. And a clamping cylinder is fixedly arranged in the middle of the upper end surface of the flitch plate. According to the utility model, the catheter is lubricated and then placed in the stomach through the nasal cavity, the traction ring on the front guide is clamped by the foreign body forceps through the suboral gastroscope and the gastroscope forceps, the catheter main body is sent to the pylorus, and the catheter main body is guided to quickly reach the horizontal section of the duodenum.

The invention discloses a nasointestinal tube intelligent positioning and nutrition monitoring method and related equipment, and relates to the field of intelligent medicines.The method comprises the steps that a plurality of pairs of conductive electrodes are arranged on a nasointestinal tube catheter body in the axial direction to collect conductivity data of the current position of the front end of the catheter; performing multi-channel acquisition and processing on the plurality of groups of conductivity data through an in-vitro conductivity detection module to obtain a continuous conductivity change curve in a catheter propelling process; on the basis of the conductivity change curve, identifying the conductive characteristics of different cavity liquids to judge whether the front end of the catheter crosses the pylorus and enters the small intestine or not; after the catheter enters the small intestine, the nutrient solution in the intestine is infused, and according to the conductivity fluctuation data, the infusion starting and ending time and the state characteristics of a target patient, dynamic trend analysis is carried out to recognize the state information of the nutrient solution in the enteric cavity. Whether the catheter crosses the pylorus to enter the small intestine or not is judged, and dependence on external confirmation modes such as X-rays is reduced.

The invention discloses a stomach wall peristalsis detection method, device and equipment based on ultrasonic waves and a storage medium, and relates to the technical field of ultrasonic imaging, the method comprises the following steps: continuously collecting dynamic echo signals of a gastric anterior wall cross section through a high-frame-rate ultrasonic probe, and ensuring high temporal-spatial resolution of original data; analyzing the difference between adjacent frames of images by adopting a phase tracking and cross-correlation algorithm, and converting the stomach wall movement into a quantifiable discrete displacement vector field; next, the discrete displacement field is fitted into a continuous propagation trajectory, and the propelling process of peristaltic waves from the stomach body to the pylorus is visually presented; secondly, key kinetic parameters such as propagation speed and creeping strength are extracted from the trajectory through a multi-scale feature fusion algorithm, and the crossing from qualitative observation to quantitative evaluation is realized; finally, through fusion visualization of vector arrows and color codes, three-dimensional information of the propagation direction, speed and intensity of the peristaltic waves is displayed at the same time, and the detection precision of gastric wall peristalsis is obviously improved.

The gastric bypass device includes an occlusion device adapted to be deployed against the patient's pyloric sphincter, an anastomotic anchor adapted to be deployed against the anastomosis between the patient's stomach and the patient's small intestine, and a tether extending through the patient's small intestine between the occlusion device and the anastomotic anchor. A dynamic leash may be secured to the occlusion device and may function with the tether to help hold the occlusion device in place. The gastric bypass device may be deployed using a variety of methods, including a push-pull wire method, a rail method, a garage method, a two-piece method, and an all-inclusive method.

To provide a device for treating obesity or diabetes free from a negative side effect caused by engagement with a mucous membrane.SOLUTION: A device (10) for treating obesity or diabetes includes a first anchor (14) disposed at a predetermined distance (D) from the duodenal tube and from a proximal end of the duodenal tract. The first anchor (14) is configured to fix the tube on a distal side of the pylorus (P) without mucous membrane involvement. A second anchor (17) in the form of a conical inflatable balloon is used to fix the device (10) in a patient's stomach (S). The duodenal tube is flexible and can be disposed in the duodenum (D) and jejunum (J) of the patient.SELECTED DRAWING: Figure 4

A gastrointestinal implant comprising a stent adapted to be positioned distal to a pyloric sphincter, within a superior duodenum of a patient, and having non-point spring elements for contacting an inner surface of the superior duodenum. A lumen of a flexible sleeve coupled to the stent receives food from the stomach and allows it to pass through the sleeve lumen without contacting gastrointestinal tissue adjacent to the sleeve. The stent may be sized to fit securely in the superior duodenum without proximal or distal migration.

The utility model relates to the field of medical instruments, in particular to a visual catheter device for pylorus dilation, which aims to solve the technical problems of lack of visual and visual operation, low dilation treatment efficiency and incapability of synchronously realizing nutrition support in the prior art, and specifically comprises a catheter body, a visual component and a dilation component, a first cavity is coaxially arranged in the catheter body, the front end of the first cavity extends to the front end face of the catheter body to form a positioning binding opening, and the rear end of the first cavity extends to the rear end face of the catheter body to form a sealed opening. The visual assembly comprises a camera, a display screen and a transmission wire, the camera and the display screen are connected and communicated through the transmission wire, and the transmission wire is sleeved with a sealing joint; by means of the built-in visual assembly, esophagus and stomach wall damage possibly caused by a traditional blind insertion mode is effectively avoided, and treatment accuracy and safety are remarkably improved.

An anchor (20) for anchoring a tube (10) with respect to a pylorus of a patient. The tube (10) may be a bypass tube or bypass conduit for bypassing a portion of the bowel. The anchor (20) may comprise a gastric bulb (22) collapsible for introduction and optionally self-expanding to an operative condition. The bulb (22) may have an open structure of a low pressure chamber. The bulb (22) may be configured to partly collapse in response to stomach contractions. This enables the bulb to exhibit compliance with the stomach contractions, and absorb the contractions. Other embodiments of tubes, anchors, balloons, and stapling, are also described.

The invention relates to a method for detecting helicobacter pylori by adopting ion mobility spectrometry, which comprises the following steps: detecting stomach helicobacter pylori by monitoring the nasal exhaled ammonia concentration change rate (CCR) of a physical examinee before and after taking non-radioactive urea, and comparing the result with the 14C / 13C urea exhaling experiment result of the physical examinee; according to the method, the concentration of exhaled gas ammonia before and after a physical examination person takes non-radioactive urea is detected by adopting a photoionization ion mobility spectrometry technology, the change rate CCR of the exhaled gas ammonia concentration at different moments is calculated, when the CCR is larger than or equal to 20.2%, the detected person is prompted to be positive of helicobacter pylori, and when the CCR is smaller than 20.2%, the detected person is prompted to be negative of helicobacter pylori. The method for detecting the helicobacter pylori is non-invasive, rapid, sensitive and simple, and is very suitable for clinically detecting the helicobacter pylori and reducing the incidence rate of gastric cancer.

A surgical method of treating reflux disease comprising the steps of dissecting the fundus at least partially down on the posterior side thereof; in the approximate direction towards bursa Omentalis, as well as away from the spleen. The method further comprising the steps of dissecting the esophagus such that the esophagus is disconnected from the surrounding tissue at least 3 cm in a cranial direction from the angle of his and connecting the fundus to the esophagus by placing at least two posterior single sutures in a posterior suture line, or a posterior continuous suture line, connecting the fundus to the esophagus, on the sinister-posterior side of the esophagus, and placing at least two anterior sutures, in an anterior suture line, or an anterior continuous suture line, connecting the fundus to the esophagus, on the sinister-anterior side of the esophagus. The method further comprises placing an implantable movement restriction device between the angle of His and the diaphragm, such that the lower esophageal sphincter is prevented from sliding through the esophageal hiatus.

The utility model relates to medical instrument technical field discloses a long -acting gastric retention drug delivery device, can enter the stomach through the oral self -ingestion mode, further realizes size change through the unfolding of elastic component, and the mechanical strength of elastic component is strengthened through water -induced hard polymer, avoids being extruded deformation and is emptied through the stomach pylorus. The device includes drug loading component, elastic component and connecting component, and the drug loading component includes multiple drug loading pieces, and the drug loading piece all has the drug loading cavity. The elastic component includes multiple elastic pieces, and the first end of multiple elastic pieces is connected with each other to make the elastic component present star -like under the unfolded state. The outer layer of elastic component is covered with reinforcing film, and the reinforcing film is formed by water -induced hard polymer solidification and can gradually transform from flexible to rigid under the aqueous environment. The connecting component includes multiple connecting pieces, and the second end of an elastic piece is connected with a drug loading piece through a connecting piece, and the connecting piece is decomposed under the preset condition, so that the drug loading piece and elastic component are separated and are discharged outside non -invasively.