2 results about "False Negative Result" patented technology

This invention relates to the field of gene detection technology, and in particular to a primer-probe combination, product, and application for detecting Alzheimer's disease. The primer-probe combination and kit provided by this invention can simultaneously detect Alzheimer's gene mutations and methylation, effectively distinguishing between Alzheimer's patients and non-Alzheimer's subjects. It achieves low-invasiveness, low cost, high sensitivity, and high specificity in Alzheimer's disease detection. The overall sensitivity for detecting Alzheimer's blood samples reaches 88.89%, and the specificity for detecting non-Alzheimer's blood samples reaches 95.74%, reducing the probability of false negatives and demonstrating high accuracy.

This invention relates to the field of detection kit technology, specifically to an African swine fever virus pathogen detection kit and detection method. This invention provides an African swine fever virus detection kit and detection method integrating specific primers and probes, a multiplex quality control system, and standardized operating procedures. By optimizing the nucleic acid extraction process, establishing a dual-channel fluorescent PCR detection system, and defining clear judgment criteria, it achieves high sensitivity and high specificity detection of African swine fever virus nucleic acid and full-process quality monitoring. It can not only accurately identify virus-positive samples but also effectively exclude false negative results through an internal standard system. This solves the key problems of insufficient specificity and low reliability of traditional detection methods, providing a stable and reliable complete technical solution for the clinical diagnosis and prevention and control of African swine fever.