237 results about "Hybrid compound" patented technology

Disclosed are hybrid opioid compounds, mixed opioid salts, compositions comprising the hybrid opioid compounds and mixed opioid salts, and methods of use thereof. More particularly, in one aspect the hybrid opioid compound includes at least two opioid compounds that are covalently bonded to a linker moiety. In another aspect, the hybrid opioid compound relates to mixed opioid salts comprising at least two different opioid compounds or an opioid compound and a different active agent. Also disclosed are pharmaceutical compositions, as well as to methods of treating pain in humans using the hybrid compounds and mixed opioid salts.

Cathode material from exhausted lithium ion batteries are dissolved in a solution for extracting the useful elements Co (cobalt), Ni (nickel), Al (Aluminum) and Mn (manganese) to produce active cathode materials for new batteries. The solution includes compounds of desirable materials such as cobalt, nickel, aluminum and manganese dissolved as compounds from the exhausted cathode material of spent cells. Depending on a desired proportion, or ratio, of the desired materials, raw materials are added to the solution to achieve the desired ratio of the commingled compounds for the recycled cathode material for new cells. The desired materials precipitate out of solution without extensive heating or separation of the desired materials into individual compounds or elements. The resulting active cathode material has the predetermined ratio for use in new cells, and avoids high heat typically required to separate the useful elements because the desired materials remain commingled in solution.

The invention relates to novel hybrid compounds comprising at least one silicone entity (Sil) in which at least one of the silicons of Sil is substituted by at least one unit—Ro-B, B being an entity of a variable nature, for example polymer, hydrocarbonated or mineral, selected from a group comprising polyols (e.g. saccharides), silicones, polyalkylene glycols, polyamides, polyesters, polystyrenes, alkyls, alkenyls, alkynyls or aryls, in addition to mineral materials such as silica and the combinations thereof. The bond Ro between the entity Sil and the entity B is obtained by means of “click chemistry” and corresponds to formula (II.1) or (II.2), Z representing a carbon atom or a nitrogen atom. Said hybrid components can be used as emulsifiers, especially for cosmetics.

The invention discloses a preparation method of a layered structure molybdenum disulfide/carbon composite material and an application. The composite material is prepared by adopting a molybdenum oxide organic/inorganic hybrid compound of an organic amine intercalation layer as a precursor, putting the precursor into a high-temperature area, putting a sulfur source into a low-temperature area and simultaneously carrying out high-temperature vulcanization and carbonization treatment under inert gas protection. The composite material has a layered structure; carbon is located between laminated plates of a few of molybdenum disulfide layers; the composite material can serve as an electronic transmission channel to improve the conductivity of the electrode material; and furthermore, the interlayer distance is expanded and the diffusion ability of Li<+>between the layers is improved. The composite electrode material has relatively high specific capacity and good cycle performance and rate capability, and is simple in process and low in raw material cost; and large-scale industrial production is easy to implement.

The object of the present invention is to provide a rare-earth magnet having a sufficient corrosion resistance, and a method of manufacturing the same. The rare-earth element in accordance with a preferred embodiment comprises a magnet body containing a rare-earth element, and a protective layer formed on a surface of the magnet body. The protective layer in accordance with a preferred embodiment includes a first layer covering the magnet body and containing a rare-earth element, and a second layer covering the first layer and containing substantially no rare-earth element. Another protective layer in accordance with a preferred embodiment comprises an inner protective layer and an outer protective layer successively from the magnet body side. The outer protective layer is any of an oxide layer, a resin layer, a metal salt layer, and a layer containing an organic-inorganic hybrid compound.

The present invention is directed towards a composition comprising, in a cosmetically acceptable carrier, at least one silicone-organic polymer hybrid compound; at least one nonionic film forming polymer; at least one amphoteric film forming polymer; and a neutralizer. The present invention also relates to methods for imparting shape to or maintaining the shape of hair wherein the composition provides style memory, strong hold and good shine, while at the same time, providing smoothness and a natural feel to the hair.

The invention is a method for permanent connection of two components by soldering employing a glass or metal solder as the solder material. A layer system providing adhesion is applied to both components, between which the solder material is introduced. the layer system is heated to a soldering temperature characteristic for the solder material and results in a permanent solder connection between both components after cooling. The layer system providing adhesion has an adhesive layer applicable directly to the component and a solderable layer. The adhesive layer, if a glass solder is used, contains oxidic, carbidic, or nitridic components or mixed compounds thereof and, if a metal solder is used, the adhesive layer contains carbidic or nitridic components or mixed compounds thereof.

A process to prepare multi-metal materials based on transition metals, using co-precipitation of mixed compound from solutions containing the metals, more specifically a process to prepare multi-metal materials based on transition metals, using co-precipitation, preferably seeking a condition of formation of a gel, from the mixture of precursor solutions containing the metals. The parameters of the process are set in such a way that the material is able to be molded by extrusion, obtaining extruded material with superior physico chemical properties, which may be used as an adsorbent, a catalyst or catalyst support, or even as filler in the reactor or column.

This invention provides a radiation detector using a scintillator having both a strong luminescence intensity and a short time constant. This invention is a radiation detector comprising as a scintillator an organic/inorganic perovskite hybrid compound represented by the general formula AMX3, wherein A is R-NH3 or R'-NH2, or a mixture thereof, R is a hydrogen atom or a methyl group which may be substituted by an amino group or a halogen atom, R' is a methylene group which may be substituted by an amino group or a halogen atom, each X is a halogen atom that may be identical to or different from the other X groups, and M is a Group IVa metal, Eu, Cd, Cu, Fe, Mn or Pd.

The invention relates to an African swine fever virus nucleic acid amplification primer, a detection method and a kit. The primer pair and the specific nucleic acid probe are selected from SEQ ID NO: 1-12. The detection method comprises the following steps: (a) amplifying nucleic acid in the sample to be detected by using a PCR primer; (b) labeling the detection probe labeled by alkyl sulfydryl group on nano gold particles; (c) hybridizing the capture probe labeled by biotin and the detection probe labeled by nano gold in step (b) with a metamorphic PCR product; (d) adding the hybrid system in step (c) to a Streptavidin-coated ELISA plate to capture the hybrid compound; (e) carrying out silver enhancement to capture nano gold; (f) and stoping the silver enhancement reaction, and visually inspecting the grey scale judgment result. The invention has the characteristics of high detection sensitivity, strong detection specificity and low detection cost, can effectively eliminate false positive or false negative result when the PCR method is used for detecting African swine fever virus, and quickly detect the African swine fever virus nucleic acid.

A kit is provided to convert a compound archery bow into a left or right handed inline (vertical limb) crossbow. The conversion kit includes a mounting plate attachable to a side of the bow riser section to hold a socket to receive a draw-lock bar which can be removed for take-down and storage. The draw-lock bar has a series of laterally spaced bolt holes to attach a grip with a trigger release latch assembly at a selectable draw length. The bar can be rotated and attached to either side of the bow, and the trigger and grip can be reposition within the trigger housing for left, right or horizontal shooting. The string latch assembly has an anti-dryfire lever that is only moved from the blocking position when an arrow is nocked. The kit also provides a hinged cocking stirrup, and a front hand vertical grip on the riser side opposite the draw-bar socket. Also disclosed is a dedicated hybrid compound bow for dedicated use with kit as an inline or traditional crossbow. The hybrid compound bow is made especially. The hybrid bow has no forehand grip, and has a shoot through riser to provide vertical and horizontal centering of the arrow to the string

The invention discloses a molybdenum-containing polyoxometalate and adamantane hybrid compound, which is prepared by connecting molybdenum-containing polyoxometalate and adamantane through a covalent bond. The preparation method comprises the following synthesis steps of: 1) performing amidation reaction on adamantane carboxylic acid serving as an initial raw material and trishydroxymethyl aminomethane to obtain N-trishydroxymethyl-adamantane carboxamide; and 2) reacting with the molybdenum-containing polyoxometalate to obtain the hybrid compound. By the invention, the molybdenum-containing polyoxometalate and the adamantine are connected through the covalent bond for the first time; and the synthesis method is simple and feasible, reaction conditions are easy to realize, purification is simple, and the yield is high. The hybrid molecule has potential application value in the aspects of medicines, lubricants, surfactants, catalysts and the like.

Aminoquinoline-antibiotic hybrid compounds in the form of hybrid molecules QA, wherein Q is an aminoquinoline and A is an antibiotic or a resistance enzyme inhibitor, their synthesis and their uses as antibacterial agent. This compound is defined by the general formula (I):

Q-(Y₁)_p—(U)_p′—(Y₂)_p″-A  (I)

in which

• • Q represents an aminoquinoline, (Y₁)_p—(U)_p′—(Y₂)_p″— is an optional spacer arm and A is an antibiotic, one of its derivatives or precursors, or a resistance enzyme inhibitor. The invention unexpectedly enables the activity of the antibiotic to be improved.

The present disclosure provides compounds, or pharmaceutically acceptable salts thereof, for inhibiting the growth of a microbe; treating a mammal having a microbial infection, malaria, mucositis, an ophthalmic infection, an otic infection, a cancer, or a Mycobacterium infection; killing or inhibiting the growth of a Plasmodium species; inhibiting the growth of a Mycobacterium species; modulating an immune response in a mammal; or antagonizing unfractionated heparin, low molecular weight heparin, or a heparin/low molecular weight heparin derivative.

A coated fertilizer is composed of fertilizer core and coated layer. The said fertilizer core contains chemical fertilizer, nutritive meta-element fertilizer and nutritive trace-element fertilizer. The said coated layer is the mixture of polyvinyl alcohol, aldehyde, water-insulable additive and filler. Its advantages are high utilization rate, high effect on increasing yield, and no pollution.

Solid electrolyte comprising organic compound containing the organic polymer with hydroxyl group, inorganic compound, and water intended to provide the solid electrolyte that is less susceptible to performance deterioration even under high temperatures of 100° C. or higher and the electrochemical system using the said solid electrolyte. It is a principal object of this invention to provide the basic means for producing the solid electrolyte comprising the hybrid compound where part of or all of the hydroxyl groups of the organic polymer with hydroxyl group are combined with at least one species of phosphoric acid and boric acid by immersing the hybrid compound in the solution containing at least one species of phosphoric acid and boric acid; otherwise by coating it with the said solution. Moreover, the said hybrid compound is made by neutralizing inorganic salt by acid in the raw material solution with the organic compound containing the organic polymer with hydroxyl group coexisting, removing solvent, where the solution after the neutralization process contains at least one species of phosphoric acid and boric acid. Hereby, part of or all of the hydroxyl groups of the organic polymer with hydroxyl group are combined with at least one species of phosphoric acid and boric acid.

As the response speed of the scintillator used in the prior art positron emission tomography device was extremely limited, there was a limit to the resolution of the positron emission tomography device. To resolve this problem, it was considered that the scintillator should have a response speed of approx. 10<-10 >seconds (0.1 ns). If such a scintillator can be manufactured, a time-of-flight PET can be realized. The inventor already discovered that if a specific perovskite organic/inorganic hybrid compound is used as a radiation scintillator, it emits visible light with a very fast (subnanosecond order) response, and that this scintillator can be used as the gamma-ray detector of the positron emission tomography device. The PET device of this invention comprises as a scintillator a perovskite organic/inorganic hybrid compound selected from the group represented by the general formulae: (R<1>-NR<11>3)2MX4 or (R<2>-NR<12>)2MX4, (NR<13>3-R<3>-NR<13>3)MX4 or (NR<14>2=R<4>=NR<14>2)MX4, or AMX3.

The present invention is an article of a film or sheet or a laminate of the film or sheet with nonwoven facing layer(s). The film or sheet is a blended compound of selectively hydrogenated thermoplastic block copolymer, a tackifying resin, and polyolefin and/or polystyrene, that has superior tensile strength and a good balance of good elasticity, low stiffness and good adhesion.

The invention intends to determine a presence ratio between mixed compounds which are difficult to separate from each other by a separation unit and cannot be discriminated by MS. In a mass spectrometer with an MSⁿ analysis function for ionizing a sample eluted from a separation unit for separating the sample into individual components, fragmenting an ion of a desired mass number, and performing a mass analysis of fragment ions, the mass spectrometer includes a database storing correlation information between an isomer presence ratio and a particular ion intensity ratio in a mass spectrum per isomer. An isomer ratio can be clarified even for a mixed sample of isomers, such as enantiomers, which are difficult to separate from each other by the separation unit and cannot be discriminated by MS.

The invention belongs to the technical field of inorganic hybridized polymer materials and particularly relates to inorganic hybridized mixed-etherified melamine resin and a preparation method thereof. The preparation method mainly includes steps: (1) etherification reaction, to be more specific, adding hexamethylol melamine, methyl alcohol and butyl alcohol into a reactor, and performing thermal reaction to obtain tetra-etherified or penta-etherified melamine resin; (2) alkali neutralization; (3) hybridization reaction; (4) distillation for removing residual methyl alcohol and butyl alcohol; (5) cooling and filtering to obtain a finished product. The inorganic hybridized mixed-etherified melamine resin prepared according to the method has advantages that by hybridization cross-linking reaction with inorganic hybrid compounds, high-temperature flame-retardant elements such as boron, molybdenum and stibium are added into amino resin generated finally, and accordingly high temperature resistance and flame retardation of the amino resin are improved, and the resin is mainly applied to preparation of combined polyether and paint.

The invention aims at producing high-purity crystals of a hydroxycarboxylic acid represented by the following formula (1):

in high yield. Provided are a method for crystallization of a compound (1) which comprises acidifying a mixture of a solution of an alkali salt of the compound (1) and an organic solvent, and a method for crystallization of compound (1) by mixing a solution of the compound (1) in a water-miscible good solvent with water, in which a slurry with a necessary suspension amount of the compound (1) for inhibiting oil formation and scaling is prepared in advance and then a main crystallization is carried out in the presence of said slurry.