427 results about "Drug detection" patented technology

The invention belongs to the technical field of medicines, and provides a cassia twig granular preparation as well as a preparation method and a product thereof. The cassia twig granule preparation is prepared from the following components in parts by weight: 35 to 50 parts of cassia twig granule extract dry paste and 50 to 105 parts of auxiliary materials, the auxiliary materials comprise lactose, beta-cyclodextrin and derivatives thereof, and citric acid. According to the invention, beta-cyclodextrin and derivatives thereof are used for replacing dextrin as an auxiliary material in the cassia twig granules, so that the interference problem of dextrin in drug detection is avoided, the formability, solubility and hygroscopicity of the cassia twig granule preparation are ensured, the stability of the preparation is improved, and the comprehensive performance is excellent.

The invention discloses a liquid medicine foreign matter detection method and system based on machine vision, and the method comprises the steps: obtaining multiband spectral data of a liquid medicine sample, and carrying out the normalization processing to generate a liquid medicine background standard spectral feature template; comparing the refractive index spectral characteristics of the template and the foreign matter-containing liquid medicine, and recording the surface roughness scattering mode and polarized light reflection angle change data of a foreign matter area; calculating a spectrum peak displacement quantized value according to the polarized light data, and extracting foreign matter edge spectrum gradient information in combination with a threshold value; calculating a transparency spectral attenuation coefficient based on the edge gradient information, and obtaining spectral contrast enhancement factors of different foreign matters in combination with the spectral response characteristic data; and if the enhancement factor does not reach the standard, adjusting the spectrum correction parameter and recalculating, fusing the scattering mode and the multi-angle incident spectrum response result to carry out consistency verification, and obtaining a final identification result containing the foreign matter material type and the danger level. The method can improve the drug detection accuracy and guarantee the drug quality safety.

The utility model provides a medicine detecting and rejecting device which comprises a support, a vacuum blowing block, a vacuum suction pipe, a vacuum exhaust pipe and a rejecting and receiving box, the vacuum blowing block and the rejecting and receiving box are respectively installed on the support, and the vacuum blowing block is provided with a plurality of hole channels. Each hole channel is correspondingly provided with a first air inlet hole, a first exhaust hole and a positive pressure hole, meanwhile, each positive pressure hole is connected with a positive pressure air source, each first air inlet hole is connected with a vacuum suction pipe, and each first exhaust hole is connected with a vacuum exhaust pipe; and one end, far away from the vacuum blowing block, of the vacuum exhaust pipe extends into the waste rejecting and receiving box. The utility model provides a vacuum negative pressure rejecting mode, and unqualified medicines are sucked into the waste box by utilizing vacuum, so that not only can the rejecting of the unqualified medicines be effectively ensured, but also the splashing of the unqualified medicines is avoided.

The invention discloses a detection method for determining N-nitroso-Vonoprasan in Vonoprasan fumarate, and belongs to the technical field of medicine detection.The detection method comprises the steps that a solution is prepared, and detection is conducted; the detection comprises the following steps: determining a test solution and a reference solution by adopting a liquid chromatography-mass spectrometry method, recording a chromatogram, and calculating the content of N-nitroso-Vonorazan according to the chromatogram and an external standard method; according to the method, a triple quadrupole rod liquid phase mass spectrometer is adopted; a chromatographic column adopts octadecyl silane bonded silica gel as a filling agent, the specification of the chromatographic column is Poroshell 120EC-C18, 1.9 mu m, 50 mm * 3.0 mm; a mobile phase is composed of a mobile phase A and a mobile phase B, and gradient elution is adopted; the ultra-high pressure chromatographic column is adopted, the operation time is shorter, the signal-to-noise ratio is higher, the detection sensitivity is higher, the detection cost is lower, and the detection requirement can be met on a low-end triple quadrupole mass spectrum.

The invention belongs to the technical field of drug detection, and particularly relates to a PCR primer pair and / or probe for detecting adulterated fritillaria in bulbus fritillariae cirrhosae or related products of bulbus fritillariae cirrhosae and application of the PCR primer pair and / or probe. Based on the PCR primer pair and / or probe provided by the invention, the adulterated fritillaria in the bulbus fritillariae cirrhosae or related products thereof is detected, the sensitivity is high, the repeatability and the precision are good, and qualitative or quantitative detection of the adulterated fritillaria in the bulbus fritillariae cirrhosae or related products thereof can be accurately realized.

Provided is a mammalian-derived cell model that can be used in anti-aging drugs. The mammalian-derived extraembryonic trophoblast cell model is an early mammalian-derived extraembryonic stage. A change model and an aging evaluation index system for differentiating the cells into the extraembryonic trophoblast cells / organoids can be used for various anti-aging researches and target detection, anti-aging drug detection, screening and identification, research on innovative drugs / natural products, and development of chemicals and / or health foods and additives. Screening and identifying many resistances is helpful. Candidate targets of aging may be further mechanically and functionally validated for future therapeutic use. The screening of anti-aging drugs or natural products will produce huge economic and social benefits.

The invention belongs to the technical field of immunodetection, and discloses a hapten and an artificial antigen for sulfonamide drug detection, a construction method and an application thereof, the structure of the hapten and the artificial antigen is shown as a formula (1): R1 =-COOH, R2 = R3 = H; r2 =-COOH, R1 = R3 = H; r3 is-COOH, and R1 is equal to R2 and H is equal to H. The invention discloses a novel sulfonamide immune hapten and a construction method of an artificial antigen of the novel sulfonamide immune hapten for the first time, and successfully obtains a specific antibody with high titer, high sensitivity and broad-spectrum recognition capability on the basis of immune animals of the artificial antigen.

The embodiment of the invention relates to the technical field of drug detection, in particular to an anti-CD38 antibody drug receptor occupation detection method and system, a peripheral blood sample is used for preparing a single-cell suspension, the single-cell suspension is divided into a TEST tube and an FMO tube, a cell surface antibody and an RO detection antibody are added into the TEST tube, only the cell surface antibody is added into the FMO tube, and only the RO detection antibody is added into the FMO tube. The TEST tube and the FMO tube are subjected to sample detection analysis, so that the average fluorescence intensity of RO detection antibodies of the TEST tube and the FMO tube is obtained. And performing RO detection analysis by adopting a dissociation method, taking the tubes which are not combined with the medicine as a total receptor group, taking the tubes which are combined with the medicine as a dissociation receptor group, and calculating an RO detection result according to the average fluorescence intensity of the TEST tube and the FMO tube.

The present invention provides a method and a detection device for detecting drugs and their metabolites in hair, which relates to the technical field of drug detection. The present invention collects hair samples, prepares samples with known drug concentration values, collects spectral data through a Raman spectrometer, inputs the spectral data matrix and the response variable matrix, analyzes them, generates a relationship matrix reflecting the correlation between the spectral data matrix and the response variable matrix, and further processes it to generate a weight vector reflecting the weight coefficients of the detection sample concentration at corresponding wavelengths. By analyzing the correlation between the weight vector and the spectral data matrix, a confidence vector that maximally reflects the directional relationship between the response variable matrix Y and the spectral data matrix X is generated, a back-projection matrix is generated after back-projection, and a confidence index is output. By comparing the confidence index with a confidence threshold, it is output whether the concentration detected by the Raman spectrometer in the current environment is valid.

Provided in the present invention is a method for detecting the fingerprint of an analgesic cream for knocks and falls, relating to the technical field of drug detection. The detection method comprises the following steps: preparing a test sample solution; preparing a reference sample solution; and injecting the test sample solution and the reference sample solution into a high performance liquid chromatograph, and recording the chromatogram. The method has the advantages of simplicity, stability, high precision, and good reproducibility. The method can conduct multicomponent fingerprint research on the analgesic cream for knocks and falls, and perform attribute research and similarity evaluation on main chromatographic peaks. The method comprehensively reflects the uniformity and stability of the analgesic cream for knocks and falls, and can evaluate, more comprehensively and scientifically, the quality of the analgesic cream for knocks and falls, thereby ensuring the quality and efficacy of the product.

The invention belongs to the technical field of medicine detection, and discloses a Raman spectrum-based traditional Chinese medicine decoction piece total flavone content detection method, which comprises: obtaining standard spectrum data of a standard flavone compound and characteristic spectrum data of a traditional Chinese medicine decoction piece sample; performing correlation degree evaluation according to the characteristic spectrum data and the standard spectrum data to obtain a flavone characteristic peak recognition matrix of each traditional Chinese medicine decoction piece sample; screening an effective characteristic wave band based on the flavone characteristic peak identification matrix; according to the spectral absorption intensity and the structure information of the effective characteristic wave band of each traditional Chinese medicine decoction piece sample, compiling a flavone quantitative characterization vector of the sample; detecting the content of total flavonoids in the traditional Chinese medicine decoction pieces on the basis of the flavone quantitative characterization vectors; the detection accuracy of the total flavone content of the traditional Chinese medicine decoction pieces is greatly improved.

The invention discloses a bladder cancer lymph node metastasis derived tumor organoid culture medium, a culture method and a rapid drug detection method, and belongs to the technical field of organoid and cell culture. The method comprises the following steps: culturing a bladder cancer lymph node metastasis-derived tumor organoid by using a bladder cancer lymph node metastasis-derived tumor organoid culture medium, immersing matrigel drops in the culture medium, and obtaining the bladder cancer lymph node metastasis-derived tumor organoid after the cultured organoid grows to 100-150 microns, to-be-detected drugs with different concentrations are directly added into the cell pore plate inoculated with the tumor organoids, the influence of the to-be-detected drugs on cell growth or metabolism is analyzed through a full-view bright-field imaging method, and the detection result of the drug for treating bladder cancer lymph node metastasis is obtained. Compared with a traditional ENR organ-like culture medium, the method has the advantages that the effect is better, and the cost is lower; the kit is used for screening medicines for bladder cancer lymph node metastasis, is simple and efficient, and can be used for accurately detecting medicines for efficiently killing bladder cancer lymph node metastasis cells.

The invention relates to the technical field of biological medicine, in particular to a drug screening model construction method based on airway organs, a model and application. The construction method of the drug screening model of the airway organoid comprises the steps of obtaining 2D airway epithelial cells, culturing the airway organoid, establishing an airway organoid inflammation model and / or establishing an airway organoid mucus secretion / goblet cell metaplasia model. Wherein the model is established according to the culture mode of the airway organ in cooperation with a specific stimulant for proliferation and differentiation. Compared with a traditional animal model, the organ-like model is low in cost and short in construction period, can better simulate the pathological process, can realize airway organ-like culture and establishment of an inflammation model and a mucus secretion / goblet cell metaplasia model at the same time, and has a good application prospect in drug detection of asthma and COPD diseases.

The invention discloses a method for detecting the content of effective components in a nerofloxacin malate capsule, and relates to the technical field of medicine detection and analysis, and the detection method comprises the following step: detecting the content of the effective components in the nerofloxacin malate capsule by adopting a high performance liquid chromatography. The invention provides the method for detecting the content of the effective components in the nerofloxacin malic acid capsule for the first time, and the inventor finds that the interference of non-effective components such as impurities and auxiliary materials in the nerofloxacin malic acid capsule can be effectively avoided by selecting a specific chromatographic column and a specific mobile phase for isocratic elution; the accuracy of detecting the content of the effective components in the nerofloxacin malic acid capsule is improved, the accurate quantification of the content of the nerofloxacin malic acid capsule is realized, and the blank in the prior art is filled.

The invention provides a preparation method and drug detection application of ZIF-8-Fe metal organic framework nano-enzyme, the ZIF-8-Fe metal organic framework nano-enzyme is prepared by adopting a heating reflux method, and peroxidase-like activity and drug detection application of the ZIF-8-Fe metal organic framework nano-enzyme are researched. In the presence of H2O2, the material can catalytically oxidize TMB to generate a blue product and shows good peroxidase activity, and through optimization experiments, proper reaction temperature and pH buffer system and optimal concentrations of ZIF-8-Fe, TMB and H2O2 are determined. Kinetic analysis shows that the affinity of TMB is superior to that of natural HRP, and a colorimetric detection method is established based on the inhibition effect of TC on the catalytic reaction. The method disclosed by the invention is reasonable in linear range, relatively low in detection limit and good in sample recovery rate and relative standard deviation performance, can be used for detecting tetracycline tablets, and shows a potential application value of the ZIF-8-Fe nano-enzyme in the field of drug detection.

The invention discloses drug residue detection equipment for aquatic product quality safety, and relates to the technical field of aquatic product drug detection.The drug residue detection equipment comprises a sampling mechanism and a pressing plate installed at the top of the sampling mechanism, a detection mechanism is arranged at the bottom of the sampling mechanism, and a detection beaker is arranged in the detection mechanism; the sampling mechanism comprises a first lifting support, a first lifting motor is fixedly mounted at the top of the first lifting support, the output end of the first lifting motor is fixedly connected with a first lifting threaded rod, and the outer side of the first lifting threaded rod is in threaded connection with a first lifting threaded sleeve; a lifting limiting block is fixedly installed on the outer side of the first lifting threaded sleeve, after liquid sampling is conducted through a heating ring, a solution can be heated and evaporated, steam is discharged through a through hole, and therefore the concentration of the solution can be increased, medicine residues can be conveniently detected, and through rotation of a fan-shaped cutting knife and a cutting sleeve, the medicine residues can be conveniently detected. And aquatic products can be conveniently cut.

The invention provides a drug detection method and device and a computer storage medium, the drug detection method comprises the steps that a blank terahertz chip and a sample terahertz chip are obtained, and the terahertz chip comprises a substrate and a metamaterial growing on the substrate; obtaining a terahertz reference time domain signal of the blank terahertz chip and obtaining a terahertz sample time domain signal of the sample terahertz chip; performing Fourier transform on the terahertz reference time domain signal to obtain a terahertz reference frequency domain spectrum signal; performing Fourier transform on the terahertz sample time domain signal to obtain a terahertz sample frequency domain spectrum signal; comparing the terahertz reference frequency domain spectrum signal with the terahertz sample frequency domain spectrum signal to obtain harmonic peak offset; and determining the drug solution concentration of the sample based on the harmonic peak offset. In this way, rapid qualitative and quantitative detection of the liquid drug solution can be achieved, and the method is easy to operate, small in sample sampling amount and easy to operate.

The present invention relates to the field of drug detection technology, and in particular to a drug detection device, including a spectrometer, wherein the spectrometer is provided with an inward detection cavity, a protective cover is hingedly connected to the inner side of the detection cavity, and a spectrometer probe for detecting tablets is provided at the bottom of the detection cavity, a shielding plate is provided in the detection cavity and above the spectrometer probe, a fixing frame is slidably connected to the inner side of the detection cavity, a shielding mechanism for opening the shielding plate is provided on the side wall of the fixing frame, a pair of rotating shafts are rotatably connected to the inner side of the fixing frame, and a circular plate is fixedly connected between the rotating shafts. Through the mutual cooperation of the above-mentioned structures, the present invention can quickly flip over the circular plate on which the drug was placed during the last detection to pour out the residue, and when the drug is pushed to the spectrometer probe for detection, the cleaning brush can be driven to rotate to further clean the residue on the flipped placement plate, thereby realizing automatic cleaning of the drug residue and greatly improving the detection efficiency of the device.

The utility model discloses a reagent bottle for drug detection, and belongs to the technical field of drug detection. Comprising a supporting base, a fixed backup plate is arranged on one side of the supporting base, a bearing ring is arranged in the fixed backup plate, a rotating rod is transversely arranged in the bearing ring, and a clamping assembly is connected to one side of the rotating rod. A limiting plate enables a double-toothed plate to controllably slide back and forth in the empty box body to drive a main gear to rotate, the main gear rotates to drive a rotating rod on one side to rotate, and the double-toothed plate reciprocates to directly drive a reagent bottle body clamped in a clamping assembly to oscillate in a reciprocating manner, so that drugs in the reagent bottle body can be stably shaken and mixed; the reagent bottles are prevented from falling off, the auxiliary gear rotates synchronously with the main gear under the movement of the double-toothed plate, and the auxiliary gear mainly plays a role in auxiliary rotation, so that the double-toothed plate can smoothly move back and forth.

The invention relates to the technical field of food detection, in particular to a composite purification filler and a pretreatment method for sulfonamide drug detection. The composite purification filler comprises carbonyl polymer particles, zinc chloride and polylactic acid, the weight ratio of the carbonyl polymer particles to the zinc chloride to the polylactic acid is 1: (0.1-0.5): (0.05-0.25). The composite purification filler provided by the invention is applied to a pretreatment method for detecting the sulfonamide residues in a meat sample, particularly a pretreatment method for detecting the sulfonamide residues in a chicken sample, so that efficient purification of the sample to be detected before detection can be simply and quickly completed.

The application provides a method for detecting psychotropic drugs in environmental sludge based on acid pretreatment, which comprises the following steps: S1: obtaining a sludge sample to be detected, performing pressurized fluid extraction on the sludge sample to be detected after freeze-drying to obtain an extraction solution, performing solid-phase extraction on the extraction solution to obtain an eluate, and redissolving the eluate to obtain a solution to be detected, wherein the pressurized fluid extraction is performed under the condition of 5 ‰ formic acid water without heating; and S2: performing liquid chromatography mass spectrometry on the solution to be detected to obtain a mass spectrum, wherein the psychotropic drug is one of eptazocine, codeine, AMP, MAMP, MDA, monoacetylmorphine, MDMA, PMMA, fentanyl, norfentanyl, ketamine, norfentanyl, benzoyl eptazocine, cocaine and tramadol, and the method realizes detection of multiple psychotropic drugs in environmental sludge.

The invention belongs to the technical field of drug detection, and particularly relates to a method for detecting lycium barbarum glycopeptide metabolites in rat plasma and tissues based on non-targeted metabonomics. According to the method, after rat lycium barbarum glycopeptides are administered through intragastric administration, blood, liver, intestine, lung and brain tissue samples after administration are collected. A UPLC-Q-TOF-MS (Ultra Performance Liquid Chromatography-Quadrupole Time of Flight Mass Spectrometry) analysis method is combined with a statistical analysis method comprising principal component analysis (PCA) and orthogonal-partial least squares discriminant analysis (OPLS-DA) to carry out in-vivo metabonomics analysis on the wolfberry glycopeptide. Then, based on a human metabolome database (HMDB), lycium barbarum glycopeptide differential metabolite is searched, so that the pharmacological action mechanism of the lycium barbarum glycopeptide is clarified from the perspective of metabolism, and a foundation is laid for deep research and development of the medicinal value of the lycium barbarum glycopeptide in future.

The invention discloses a method for determining related substances in a loxoprofen sodium patch in the technical field of drug detection, and aims to solve the technical blank existing in determination of related substances in a loxoprofen sodium patch in the prior art. The method comprises the following steps: respectively weighing a loxoprofen sodium reference substance and an impurity reference substance, and adding a solvent for dilution to prepare a reference substance solution; taking a loxoprofen sodium patch, stripping a protective layer, adding tetrahydrofuran and methanol, shaking to separate the paste from a backing layer, adding water, shaking again, adding a solvent for dilution, uniformly mixing, centrifuging, and taking supernate to obtain a test solution; injecting the prepared reference substance solution and the test solution into a high performance liquid chromatograph for determination to obtain peak areas of the reference substance solution and the test solution; and calculating the content of the related substances in the loxoprofen sodium patch by adopting an HPLC correction factor method according to the peak areas of the reference solution and the test solution. The method is suitable for measuring the content of the related substances in the loxoprofen sodium patch.

The invention relates to a detection method of a revivacin inhalation solution, and belongs to the technical field of medicine detection. According to the detection method provided by the invention, a revivin inhalation solution sample is analyzed by adopting high performance liquid chromatography to obtain the content of impurities in the revivin inhalation solution; the high performance liquid chromatography uses a phosphate buffer as a mobile phase A and acetonitrile as a mobile phase B, and the elution conditions are as follows: 0-5 min, the volume ratio of the mobile phase A to the mobile phase B is gradually changed from 95: 5 to 80: 20; the volume ratio of the mobile phase A to the mobile phase B is gradually changed from 80: 20 to 20: 80 in 5-30 min; the volume ratio of the mobile phase A to the mobile phase B is 95: 5. The method provided by the invention can realize accurate detection of five different impurities in the revienacin inhalation solution, and is beneficial to actual production quality control and improvement of drug safety.

The invention relates to the technical field of drug detection, in particular to a molecularly imprinted sensor for quantitatively detecting olanzapine in human blood as well as a preparation method and application of the molecularly imprinted sensor. Au-Pt NSF is deposited on the surface of a substrate electrode through an HBDT method, then a molecularly imprinted polyaniline layer is prepared through electro-polymerization, and the molecularly imprinted sensor is formed. A classical redox probe potassium hexacyanoferrate is used as a tool, and DPV is used for monitoring current change (delta I) caused by olanzapine addition, so that sensitive quantitative detection of olanzapine is realized. The sensor prepared by the invention shows a good linear relationship to olanzapine in the concentration ranges of 0.005-0.4 mu M and 0.4-10 mu M, the detection limit is 0.94 nM, and the sensor has high reproducibility and stability (relative standard deviation RSDlt;

The invention belongs to the technical field of medicine detection, and particularly relates to dipropyl malonic acid prepared by a dimethyl malonate method and a detection method of impurities of the dipropyl malonic acid. According to the detection method provided by the invention, the dipropyl malonic acid prepared by a dimethyl malonate method and impurities thereof are detected through high performance liquid chromatography (HPLC) for the first time; the impurities comprise propyl malonic acid, 2-methyl-2-propyl malonic acid, 2-propyl-2-butyl malonic acid, propyl malonic acid monomethyl ester, 2-methyl-2-propyl malonic acid monomethyl ester, dipropyl malonic acid monomethyl ester, 2-propyl-2-butyl malonic acid monomethyl ester, propyl malonic acid dimethyl ester, dipropyl malonic acid monopropyl ester and propyl malonic acid dimethyl ester; the invention relates to a method for preparing dipropyl malonic acid, which is selected from one or more of dipropyl malonic acid dimethyl ester, dipropyl malonic acid methyl ester propyl ester and 2-propyl-2-butyl malonic acid dimethyl ester, and solves the problems of quality control and process evaluation of dipropyl malonic acid serving as an intermediate of sodium valproate prepared by a dimethyl malonate method.

The invention relates to the technical field of data processing, in particular to a pharmaceutical production whole-process quality tracing method and system applying a block chain technology, and the method comprises the steps: obtaining a liquid matrix composed of pixel values of a liquid region in an injection bottle; obtaining an effective test region in the liquid matrix by using a region growth method; processing the pixel value of the effective test area to obtain an enhanced matrix; training a recognition network to recognize impurity types in the enhancement matrix; acquiring an enhanced matrix in the production process, and identifying whether impurity types exist or not by using the trained identification network; and in response to the existence of the impurity type, prompting related personnel to perform quality inspection on the corresponding production process. The method has the effects of improving the drug detection accuracy and providing a reliable data basis for subsequent drug traceability.

This invention discloses an intelligent batch dispensing device for mother liquor powder, comprising: a dispensing frame assembly including a first accommodating part and a second accommodating part; a frame rotation assembly including a rotation drive assembly and a rotation mounting base; a first feeding mechanism including a powder bottle feeding assembly and a powder bottle translation assembly; and a second feeding mechanism including a mother liquor bottle feeding assembly and a mother liquor bottle translation assembly. According to this invention, the intelligent batch dispensing device for mother liquor powder saves dispensing space due to the vertical arrangement of the first and second accommodating parts; a drug detection device is provided to read and identify the fixture and drug information; and the frame rotation assembly drives the rotation of the dispensing frame assembly, enabling the powder bottle translation assembly or the mother liquor bottle translation assembly to dispense the drug quickly and accurately, thereby improving dispensing efficiency.

The present invention relates to a method for analyzing and detecting related substances of desloratadine, and belongs to the technical field of drug detection and analysis. In order to solve the problem of low detection efficiency and low precision in the existing detection, a method for analyzing and detecting related substances of desloratadine is provided, and high performance liquid chromatography is used for detection, including the following chromatographic conditions: isocratic elution is adopted; 1.0g to 1.1g of sodium dodecyl sulfate and 0.86g to 0.88g of sodium dihydrogen phosphate are contained in each 550ml of water in the mobile phase; the volume ratio of water: triethylamine: acetonitrile: methanol in the mobile phase is 550: 1.4 to 1.6: 285 to 320: 145 to 156; phosphoric acid is used to adjust the pH value to 2.8 to 3.3. The present invention can produce peaks and can be separated from each other, with good separation, and the peaks of each impurity such as impurity A and the main peak do not overlap, so that high-efficiency detection and analysis are achieved, and the detection accuracy is high.

We provide a flexible, AI-powered wearable patch system for non-invasive medication compliance monitoring. [Solution] This system 100 integrates physiological sensors 101 to detect heart rate variability, skin temperature, electrocutaneous activity, and swallowing-related muscle signals. A drug detection sensor 102 identifies interactions with drug containers, and a medication event sensor 103 detects gestures or physiological signals indicating medication. An embedded AI processor 104 receives multimodal sensor data and performs digital filtering, normalization, artifact removal, and machine learning-based classification to determine medication confirmation events, missed doses, or irregular medication patterns. A power management unit 105 controls the power supply to ensure continuous operation. A wireless communication module 106 transmits processed medication data to an external device. This enables reliable, objective, and real-time medication confirmation without relying on invasive ingestion sensors or patient reports.