204 results about "Stomach part" patented technology

The invention discloses a vitamin K2 composite micro-capsule system with stomach protection and intestine slow release functions and a preparation method and application thereof, the vitamin K2 composite micro-capsule system with stomach protection and intestine slow release functions comprises three layers, namely a core layer, a middle layer and an outer layer from inside to outside in sequence; the core layer is formed by coating vitamin K2 with a zein-lac hydrophobic core, the middle layer is a pea protein-pectin electrostatic compound, and the outer layer is sodium alginate and chitosan double-network gel. The micro-capsule system provided by the invention can be tightly combined in a gastric acid environment after being orally taken, the release of active ingredients in the stomach is reduced, and then the micro-capsule system stays at intestinal mucosa for a long time and slowly releases contents, so that the functions of the micro-capsule system are slowly presented outside, the half-life period is prolonged, and the action effect is improved. Vitamin K2 directly or indirectly participates in and regulates various physiological processes related to health, and plays an important role in the aspects of maintaining bone health, preventing cardiovascular diseases, protecting nerves, improving metabolism and the like.

The present invention discloses a nasogastric feeding device for nursing the digestive tract with anti-backflow, which relates to the field of nasogastric feeding technology, including a feeding device and a hose, wherein the feeding device includes a driving rod and a housing, the upper and lower ends of the housing are respectively provided with end caps and a sleeve, a pressing plate and a mesh plate are installed inside the housing, a cavity is formed between the end cap and the sleeve, a four-way pipe is installed on the end cap, an air pump and a control valve are installed inside the four-way pipe, the pressing plate and the mesh plate are provided with a driving rod, and the four ports of the four-way pipe are respectively connected to the external environment, the cavity, the air pump and the space inside the housing. The present invention performs air extraction before food processing to prevent the liquid food from carrying a large amount of air into the patient's stomach during the infusion period, thereby preventing the patient from experiencing bloating. At the same time, the hose is provided with an anti-backflow mechanism to prevent the phenomenon of gastric fluid backflow due to the patient's body posture.

A system for imaging one or more particular structures in the stomach within a workspace is provided. In one embodiment, the system comprises: a) an active capsule endoscope positionable in the stomach, comprising a camera, an inertial measurement unit, and a permanent magnet; the driving unit comprises a Hall sensor array located at the bottom of the working space and a plurality of magnetic field generators used for generating expected magnetic fields; and c) a control unit.

The invention belongs to the technical field of biology, and particularly discloses a pH response type probiotic-liposome hybrid system, a preparation method and application thereof, and the pH response type probiotic-liposome hybrid system comprises engineered escherichia coli Nissle 1917, pinocembrin-loaded biotinylated liposome and an enteric polymer; wherein the engineered escherichia coli Nissle 1917 is in non-covalent binding with the biotinylated liposome loaded with the pinocembrin through surface display streptavidin, so that EcNPIN is formed, and the EcNPIN is coated with an enteric polymer, so that the pH response type probiotic-liposome hybrid system is formed. The pH response type probiotic-liposome hybrid system EcNPIN-L provided by the invention can resist the acidic environment of the stomach, completes pH response release and colonization in the intestinal tract, solves the problems of lack of intestinal tract localization of drugs and low probiotic treatment efficiency, improves the local intestinal tract concentration of pinocembrin, and promotes intestinal tract colonization of probiotics.

The invention provides a stomach tube space registration and dynamic positioning method based on historical features, and relates to the technical field of medical instruments, and the method comprises the following steps: data acquisition: recording a catheterization path curve when the catheterization of a patient succeeds, and determining the catheterization path curve as a physiological feature curve; data calibration: marking coordinates of key feature points such as an airway opening, key parts of an esophagus and a stomach entrance on the physiological feature curve; space registration: registering the real-time catheter advancing curve and the physiological characteristic curve in the same coordinate system, and aligning data; dynamic positioning: calculating the position deviation of the front end of the stomach tube, dynamically calibrating based on a deviation value, and controlling the stomach tube to move along a physiological characteristic curve, in the data acquisition step, the physiological characteristic curve is used as a historical reference for path matching in a subsequent tube indwelling process, and in the data calibration step, the tube indwelling control precision is improved by more than or equal to 15% by dividing characteristic sections; and by utilizing a historical physiological curve, the catheterization path deviation is less than or equal to 2mm, and the control precision is improved by 30%.

The invention provides application of bifidobacterium breve in preparation of a product for resisting gastric ulcer and gastric inflammation caused by helicobacter pylori, and belongs to the technical field of microorganisms. The preservation number of the bifidobacterium breve NKU BB1-2 is GDMCC NO: 65956, and the bifidobacterium breve NKU BB1-2 can antagonize helicobacter pylori colonization and relieve gastric ulcer aggravation caused by helicobacter pylori. The bifidobacterium breve NKU BB 1-2 has good helicobacter pylori antagonism ability in an in-vitro environment, and can significantly inhibit colonization growth of helicobacter pylori; animal experiments show that the bifidobacterium breve NKU BB 1-2 can relieve gastric ulcer aggravation caused by helicobacter pylori infection in vivo, and the gastric mucosa lesion is relieved, the stomach inflammation is relieved, and the stomach pH value is increased; in addition, the bifidobacterium breve NKU BB1-2 can also significantly improve the diversity of stomach microorganisms, regulate and improve the structure of the stomach microorganisms, and assist antagonism and removal of helicobacter pylori infection.

The invention relates to the field of animal health detection, and discloses a health detection method and equipment based on cattle stomach data and a storage medium. The method comprises the following steps: collecting characteristic time sequence data of a cattle stomach through an implantable stomach capsule; performing health state labeling processing on the feature time sequence data to obtain labeled feature data; performing parameter optimization processing on the preset linear regression model to obtain a first analysis model; performing parameter optimization processing on the preset random forest model to obtain a second analysis model; the method comprises the following steps: collecting monitoring time sequence data of a cattle stomach through an implantable stomach capsule; performing detection processing on the monitoring time sequence data to obtain a first analysis value, and performing detection processing on the monitoring time sequence data to obtain a second analysis value; and generating a health state corresponding to the cattle based on the first analysis value and the second analysis value. In the embodiment of the invention, under the condition that the deviation ratio of the analysis value is not high, the effect of detecting the accurate cattle health state based on the physiological data of the cattle stomach is realized.

An apparatus for treating obesity of a patient having a stomach with a food cavity. The apparatus comprising a volume filling device adapted to be at least substantially invaginated by a stomach wall portion of the patient with the outer surface of the volume filling device resting against the stomach wall, such that the volume of the food cavity is reduced in size by a volume substantially exceeding the volume of the volume filling device. The apparatus further comprises at least one adjustable stretching device adapted to be at least substantially invaginated by a stomach wall portion of the patient with the outer surface of the stretching device resting against the stomach wall and adapted to stretch a portion of stomach wall, and a fluid connection device interconnecting the volume filling device and the stretching device.

The invention discloses a long-acting pellet suitable for gastric absorption and a preparation method of the long-acting pellet. The long-acting pellet is prepared from the following components in parts by mass: 0.01-1 part of a medicine, 1-2.5 parts of a filler, 0.2-0.7 part of a modified pore-foaming agent mixture, 1-2.5 parts of an improved adhesive mixture and 0.1-0.7 part of an improved sonokinetic response agent. Wherein the modified pore-foaming agent mixture is prepared from a modified pore-foaming agent and glycosylated saponin, the modified pore-foaming agent is prepared by mixing a pore-foaming agent and seleno-amino acid according to a mass ratio of 4: 1, the improved adhesive is mixed with the adhesive through BHP-SH, and ionic crosslinking is performed by using CaCl2 to form a covalent ion dual network, so that the stomach adhesiveness is enhanced; the sonokinetic response agent is improved by the coated poria cocos extract, and the long-acting pellet is prepared by adopting a wet granulation method or a fluidized bed method, has the characteristics of slow release, long acting, targeted stomach absorption and responsive drug release, and is suitable for treating stomach diseases such as gastritis.

The invention discloses a medical organ image automatic segmentation and discrimination marking system based on deep learning. The system comprises an acquisition module, an identification module, a determination module, a determination module, an adjustment module, a marking module and an output module. According to the method, temporary grids are preliminarily screened out by analyzing the ratio and the surface roughness of deep color areas; determining key grids in combination with physiological status characteristics such as saturation and creeping frequency; the threshold value is dynamically adjusted according to key grid data, and the accuracy is improved; and finally, synthesizing the echo uniformity and the ideal polyp image, and determining the target polyp image, thereby reducing the risk of errors of a single model, facilitating the reduction of missed diagnosis and misdiagnosis, improving the diagnosis reliability, assisting the formulation of a scientific treatment scheme, and improving the diagnosis efficiency. The problems of inaccuracy in polyp recognition and inaccuracy in image segmentation caused by poor adaptability to unstable stomach peristalsis due to excessive dependence on a model are effectively solved.

The invention belongs to the technical field of microorganisms, and particularly relates to lactobacillus plantarum HNGD-YC1 capable of degrading free-state advanced glycosylation end products (AGEs) and application of the lactobacillus plantarum HNGD-YC1. The strain is classified and named as Lactobacillus plantarum, and the preservation number of the strain is CCTCC M 20251498. The strain can effectively degrade free AGEs, and has good acid resistance and cholate resistance. Besides, lactic acid bacteria are adopted for degrading free AGEs in food for the first time, the degradation rate is 69.3%, and the lactobacillus has an excellent probiotic function, is high in strain activity, can easily pass through the stomach and be planted in the intestinal tract and is low in economic cost; the invention provides a novel safe and sustainable method for solving the problem that the food-sourced harmful factor AGEs enters the body to damage the health, and also provides a safer and more effective diet strategy for people with AGEs-related metabolic diseases, thereby being beneficial to promoting the healthy life of people.

A method of deploying an intraluminal device to the cardiac region of the stomach and an intraluminal system used to deploy an intraluminal device to the cardiac region of the stomach, wherein the intraluminal device has a wall defining a surface and an open portion of the surface that is adapted to be aligned with the gastroesophageal (GE) junction. The surface and the cardiac portion of the stomach are conformable with each other. The method includes deploying the intraluminal device trans-orally to the stomach with an endoscopic deployment device and retaining the device against the cardiac region of the stomach with the open portion generally aligned with the GE junction. The intraluminal device is fastened to the stomach from the abdominal cavity with at least one laparoscopic instrument while concurrently visualizing the device with an endoscope in the stomach while it is being fastened. The laparoscopic instrument is adapted to respond to the endoscope in order to adjust location between the laparoscopic instrument and intraluminal device while the laparoscopic instrument is fastening the intraluminal device.

The present application relates to the technical field of Raman spectrum detection, and in particular to a stomach H. pylori infection detection method based on Raman spectrum. The method performs Raman spectrum detection on a gastric juice sample to obtain a Raman spectrum curve; a healthy Raman spectrum curve of a healthy gastric juice sample is obtained and constructed into a healthy sample spectrum library; according to the Raman intensity difference and waveform distribution similarity of each healthy Raman spectrum curve in the healthy sample spectrum library with other healthy Raman spectrum curves in a specified wavelength range, a representative weight of each healthy Raman spectrum curve is obtained; according to the Raman intensity distribution similarity of the Raman spectrum curve of the current patient with each healthy Raman spectrum curve in the specified wavelength range and the representative weight of each healthy Raman spectrum curve, the infection degree of the current patient is obtained, and it is determined whether the current patient is infected with H. pylori. The present application effectively improves the preparedness and universality of H. pylori detection by obtaining the infection degree.

This invention discloses a pharmaceutical composition and its preparation method for treating atrophic gastritis, precancerous lesions of the stomach, and stomach cancer, belonging to the field of traditional Chinese medicine preparation technology. The pharmaceutical composition is prepared by a specific two-step microbial fermentation process using Astragalus membranaceus, Hericium erinaceus, Curcuma zedoaria, Actinidia chinensis root, Camptotheca acuminata fruit, Hedyotis diffusa, Coptis chinensis, Taraxacum mongolicum, Viola yedoensis, Corydalis yanhusuo (processed with vinegar), Phellodendron chinense, Solanum nigrum, Scutellaria baicalensis, Panax notoginseng, Zingiber officinale, Piper cubeba, Cuttlebone, Fritillaria thunbergii, roasted soybean, and red yeast rice. This invention significantly improves the bioavailability of the active pharmaceutical ingredients through the synergistic effect of the multifunctional groups of traditional Chinese medicine and the enhanced effect of microbial fermentation. It can systematically reverse gastric mucosal atrophy and intestinal metaplasia, effectively improve microcirculation, and inhibit Helicobacter pylori, while also exhibiting good safety. This provides a novel and effective treatment for the aforementioned gastric diseases.

The invention discloses a novel multi-dimensional cascade assembled micro-nano intestinal delivery carrier and a preparation method and application thereof, and relates to the field of biological medicine and functional materials.The preparation method comprises the following steps that S1, phospholipid and a sterol regulator are dissolved in an ethanol solution to form a lipid film, the solution is added for hydration, and the lipid film is obtained; then treating to obtain a monodisperse vesicle suspension; s2, adding the vesicle suspension into the composite solution, and inducing adsorption of an inner shell layer to form intermediate particles; and S3, dropwise adding a cationic electrolyte solution into the intermediate particle suspension, and carrying out interface electrostatic complexing and coordination cross-linking reaction to obtain the delivery carrier. By constructing a cascade self-assembly delivery carrier with a multi-layer core-shell structure, the problem that a large amount of drugs are inactivated due to insufficient shielding in an extreme stomach environment can be solved, so that space-time limited release of the drugs in specific parts of intestinal tracts is realized, and oral bioavailability and targeted therapy efficiency are greatly improved.

The invention relates to the field of animal husbandry monitoring, and discloses a health monitoring method and equipment based on gastric capsule acquisition data, and a storage medium. The method comprises the following steps: based on a stomach capsule, collecting data of a cattle stomach; according to a physiological pressure algorithm, performing pressure calculation processing on the PH time sequence data, the body temperature time sequence data, the rumination frequency time sequence data and the stomach pressure time sequence data to obtain pressure time sequence data; obtaining multi-modal time sequence data based on a feature fusion algorithm; according to the sliding window parameters, performing window cutting processing on the multi-modal time sequence data to obtain multi-modal cutting data; according to a Bi-LSTM model, performing feature mapping processing on the multi-mode cutting data to obtain a time sequence feature vector; and according to the random forest model, performing evaluation processing on the combined cutting data to obtain health state data of the cattle. According to the embodiment of the invention, the accuracy of analyzing the health state of the ruminant animal by collecting the temperature data is improved, and a large amount of complicated manual analysis processes are avoided.

The present application relates to a kind of brain health nutrition capsule and its preparation method, belong to the technical field of functional health food.The preparation method includes the following steps: taking walnut kernel powder, DHA algal oil microcapsule powder, phosphatidylserine, ginkgo biloba extract and oligosaccharides are mixed, soft material is prepared by adding purified water, granulation is extruded by screen, and granule core is obtained by drying;Granule core is coated, and brain nutrition core granule is obtained by drying;Prepare base nutrition layer granule;Brain nutrition core granule and base nutrition layer granule are mixed, and composite granule is obtained, and composite granule is filled into capsule.The present application not only solves the three major obstacles of oxidation, precipitation and vitamin degradation of high polyphenol walnut base formula in gastric acid environment, but also unexpectedly builds from stomach protection to intestinal microecological optimization, finally realizes the cascade effect of brain nutrition efficient absorption, meets the core needs of teenagers brain health and intelligence, and truly realizes the effect of brain health and intelligence.

The invention is suitable for the technical field of medicine, and provides a stomach medicine capsule and a preparation method thereof, the stomach medicine capsule is prepared from 20-30 parts of Chinese angelica, 7-11 parts of phoenix-tail fern, 15-19 parts of radix berberidis, 5-9 parts of radix aucklandiae, 2-4 parts of reed seed, 13-17 parts of sea snail and auxiliary materials; the preparation method comprises the steps of raw material pretreatment, ethanol reflux extraction, vacuum concentration, spray drying, mixing granulation, capsule filling and packaging. The traditional Chinese medicine raw materials in a specific proportion are screened, the synergistic effect of resisting inflammation and bacteria, regulating qi to relieve pain, nourishing blood and repairing, and relieving acid and protecting the stomach is achieved, and the problems that an existing stomach medicine is single in effect and large in side effect are solved; meanwhile, extraction and drying processes are optimized, the dissolution rate of effective components and the stability of the preparation are improved, and the traditional Chinese medicine composition is suitable for treating stomach diseases such as acute and chronic gastritis, gastric ulcer and hyperacidity, high in safety and suitable for long-term administration.

The utility model discloses a kind of gastric cavity plugging catheters of gastrostomy in the medical instrument technical field, the device increases plugging balloon and sealing clamping piece, can be held by inside and outside, hold stomach wall and skin to position the device, while plugging balloon seals and isolates the puncture of stomach wall inside gastric cavity, effectively avoid gastric juice to flow out, avoid gastric juice to overflow along the puncture and cause skin burning;Positioning baffle is also increased, can be unfolded inside duodenum, positioning baffle can position nutrition tube, avoid nutrition tube to slide and separate, can also effectively block pylorus, effectively avoid enteric digestive juice to enter stomach, and do not hinder gastric juice to flow into intestine normally, and by pressure relief port and pressure relief pipe, stomach is conveniently decompressed, effectively avoid that pressure is too high and nutrition liquid is refluxed to esophagus.

The invention discloses a gastrointestinal decompression, drainage and pressure stabilization device, which belongs to the field of gastrointestinal drainage and comprises a drainage tank main body. A first one-way valve is installed on the left side of the upper surface of the drainage tank body, a filtering assembly is arranged on the surface of the upper end of the first one-way valve, a first connector is arranged on the upper surface of the filtering assembly, a first connecting hose is arranged at the tail end of the first connector, and a negative pressure tank is installed at the tail end of the first connecting hose. Through the arrangement of the negative pressure tank and the high pressure tank, when gas in the stomach of a patient is too much, the pressure in the patient can be rapidly reduced through the negative pressure tank, and mucosa injury caused by too high negative pressure is avoided. When the high-pressure tank detects that the pressure of the stomach of the patient is too low, in order to protect the stomach, the pressure of the stomach of the patient can be stabilized by controlling the electromagnetic valve to be opened, a more stable pressure environment is provided for treatment of the patient, and the treatment effect is improved; and discomfort and potential risks caused by excessive pressure fluctuation to the patient are reduced.

The invention discloses a control method of an artificial stomach, and belongs to the technical field of bionic medical instruments. Under the state that the starting signal is monitored, all the driving pieces are controlled to drive the diastole assembly according to a preset time sequence, so that the corresponding part of the artificial stomach is subjected to contraction or diastole movement, and the content in the artificial stomach is subjected to regular movement from the inlet direction of the artificial stomach to the outlet direction of the artificial stomach. By changing the time point and interval of successive movement of the whole stomach diastole assembly, the pathological characteristics of peristaltic wave conduction delay and starting time sequence disorder are simulated, and then by adjusting the interval between the contraction stop time point and the expansion starting time point, the expression of abnormal extension of the diastole and contraction switching interval or interruption of the peristaltic wave in the pathological state is re-engraved.

1. The name of the design product: stomach tube. 2. The use of the design product: the design product is used for the extraction, collection of gastric juice and administration to the stomach. 3. The design points of the design product: in shape. 4. The picture or photo that best indicates the design points: perspective view 1.

The invention relates to the technical field related to microcapsules, in particular to a preparation method of a wheat alpha-glucosidase inhibitory peptide microcapsule, which comprises the following steps: by taking wheat vital gluten as a raw material, carrying out enzymolysis by alkaline protease to obtain alpha-glucosidase inhibitory peptide, and then carrying out enzymolysis by adopting a sodium alginate-chitosan composite wall material system to obtain the wheat alpha-glucosidase inhibitory peptide microcapsule. By optimizing key parameters such as the core-wall ratio of 1: 2.632, the calcium chloride concentration of 2.48% and the curing time of 31.83 min, the double-layer microcapsule with the pH response characteristic is prepared by an ionic gel method. The embedding rate of the prepared microcapsule reaches 78.26%, the 2-hour release rate in simulated gastric juice (pH 2.0) is smaller than or equal to 21.38%, the 4-hour accumulative release rate in simulated intestinal juice is larger than or equal to 84.98%, and stomach protection and intestinal targeted release of the active peptide are achieved; meanwhile, the peptide loss rate of the product under the storage condition of 4 DEG C is less than or equal to 11.13%, the loss rate in the environment with the pH value of 2.0 is only 12.72%, and the stability of the active peptide is remarkably improved. The obtained product can effectively protect the activity of the alpha-glucosidase inhibitory peptide and improve the bioavailability of the alpha-glucosidase inhibitory peptide, and a new scheme is provided for developing functional hypoglycemic food.

The invention provides a gastrointestinal nutrition tube and belongs to the technical field of gastrointestinal tubules, the gastrointestinal nutrition tube comprises a tube body, the tube body is provided with a near end, a far end, an adjusting channel and an injection channel, the adjusting channel and the injection channel extend between the near end and the far end, a buffer film is arranged on the outer wall of the tube body, and a feeding hole and a discharging hole are formed in the buffer film. The feeding hole is communicated with the adjusting channel, the discharging hole penetrates through the pipe wall of the adjusting channel so that the buffer film can be communicated with the injection channel, a blocking piece is arranged in the adjusting channel, and the blocking state of the blocking piece on the feeding hole and the discharging hole can be adjusted by moving the position of the blocking piece in the adjusting channel. When the gastrointestinal nutrient canal is used, warm water is injected into the adjusting channel through the second connector, the warm water can enter the buffer film through the feeding hole, the buffer film can expand and block cardia or pylorus, and substances entering the stomach or enteric cavity can be effectively prevented from flowing back from the cardia or pylorus.

The invention belongs to the technical field of gastric lavage devices, and particularly relates to a flow-adjustable gastric lavage device for children, which comprises a mounting base, a fixing part is arranged in the mounting base, a liquid storage part is arranged in the fixing part, a butt joint part is further arranged in the mounting base, and the lower end of the butt joint part is communicated with the liquid storage part. The upper end of the butt joint part is connected with the flushing part, the cleaning liquid in the liquid storage part is conveyed to the flushing part through the butt joint part, the cleaning liquid is conveyed to the stomach through the flushing part, meanwhile, waste liquid obtained after cleaning of the flushing part can be extracted, and cleaning of the stomach and recycling of the cleaning liquid are achieved. According to the invention, first aid can be adapted through convenient operation, and the process is simplified through tool-free quick docking; safety protection is comprehensive, double-tube isolation and scratch prevention are achieved, and mild negative pressure guarantee is achieved; the treatment efficiency and tolerance are high, the effect is improved through parallel conveying and recycling, and discomfort of children is reduced.

The invention discloses TRuC-T cells capable of improving safety of targeted CLDN18.2 immune cells and application of the TRuC-T cells. The TRuC-T cells comprise AB011TRuC-T and F2H TRuC-T. According to the TRuC-T cells, the effective killing capacity on tumor cells is reserved, meanwhile, toxicity to normal stomach tissue is remarkably reduced, the technical problem of stomach side effects in an existing CLDN18.2 targeted therapy is effectively solved, and the TRuC-T cells can be used for improving the safety of the targeted CLDN18.2 immune cells. The invention provides a better choice for precise treatment of CLDN18.2 positive solid tumors, and has important scientific significance and clinical application value.

The application discloses a kind of based on magnetic torsion spring's bistable state stomach anchoring magnetic drive biopsy capsule robot, including camera module, biopsy module, magnetic torsion spring module and stable state switching module.Based on the bistable state structure of magnetic torsion spring.Two radial magnetization magnets in capsule are close, connecting rod is retracted, and the first stable state of capsule is obtained by driving magnet, and the robot is rolled to target position;And two radial magnetization magnets are far away, connecting rod is stretched, and the second stable state of robot is completed anchoring, and the lesion tissue is biopsied, and by applying external magnetic field, it is switched between two stable states, i.e., capsule can be actively moved to lesion tissue, and multiple anchoring multiple biopsy can be completed.

This invention relates to the field of pharmaceutical formulation technology, specifically to a sustained-release formulation of rifabutin, and more specifically, to a sustained-release rifabutin formulation composition for treating Helicobacter pylori infection. The key technical point of this invention is that it uses a novel antibiotic for treating Helicobacter pylori infection as the active ingredient, supplemented with specific inactive ingredients, including a hydrophilic gel-type matrix sustained-release material, a swelling agent, a buoyancy aid, and a lubricant. Through the synergistic effect of the hydrophilic gel-type matrix sustained-release material, the swelling agent, and the buoyancy aid, the composition can rapidly swell in gastric juice and maintain a floating state, thereby significantly prolonging the residence time of the formulation in the stomach and upper small intestine. This invention solves the technical problem of conventional formulations having a short residence time in the stomach and requiring frequent administration to maintain an effective antibacterial concentration, achieving the goal of effectively eradicating Helicobacter pylori by reducing the number of doses while maintaining an effective concentration at the site of infection for a longer period.

The invention belongs to the technical field of traditional Chinese medicine, and particularly relates to a traditional Chinese medicine composition with the function of relieving stomach inflammation and a preparation method and application. The traditional Chinese medicine composition comprises a main medicine and an auxiliary medicine, the main medicine consists of cuttle bone, thunberg fritillary bulb and rheum officinale; the adjuvants comprise a first adjuvant and a second adjuvant; the first adjuvant is belladonna and daphniphyllum calycinum; the second adjuvant comprises fructus aurantii and cortex magnoliae officinalis. The traditional Chinese medicine composition provided by the invention is simple in component, only a trace amount of belladonna extract needs to be added, meanwhile, daphniphyllum calycinum is compounded, the addition of excessive other unnecessary components is avoided, and the symptom of chronic non-atrophic gastritis with erosion can be remarkably improved.