51 results about "Pleuroperitoneal" patented technology

The invention provides a robot for assisting a minimally invasive surgery of the pleuroperitoneal cavity and relates to a robot for clamping an endoscope and a surgical instrument in the minimally invasive surgery of the pleuroperitoneal cavity to overcome the shortcoming that in the traditional minimally invasive surgery process, unstable focus image display is caused by hand trembling and fatigue of an assistant due to long-time endoscope and surgical instrument holding, and a stable and continuous surgical drag force cannot be provided for the focus tissue. The robot comprises a base, a middle mechanical arm and side mechanical arms. The middle mechanical arm comprises a positioning joint and an end effector for clamping the endoscope. The positioning joint comprises a swing joint I, a swing joint II, a swing joint III and a swing joint IV. Each side mechanical arm comprises a swing joint V and a rotating joint. Each of the rotating joint and the five swing joints comprises a clutch, an encoder, a rotating shaft and a locking and swing measuring mechanism of a shaft sleeve. The robot is used for the minimally invasive surgery of the pleuroperitoneal cavity.

The invention discloses a simulation device for human body pleuroperitoneal cavity movement caused by breathing. The simulation device comprises a workbench, a base, a support, a drive motor, lead screw, a slide block, a push plate, a needle cylinder body, a needle cylinder piston and a push rod, wherein the base and the support are sequentially arranged on the workbench, the drive motor is arranged on the base, the lead screw is connected with the output end of the drive motor through a coupling, the slide block is arranged on the lead screw and can move leftwards and rightwards along with rotation of the lead screw, and the push plate is perpendicularly arranged at the top of the slide block; the needle cylinder body is arranged on the support, a needle cylinder piston is arranged in the needle cylinder body, and the push rod is connected with the exterior of the needle cylinder piston; the push rod is fixedly connected with the push plate, meanwhile a needle nozzle of the needle cylinder body is provided with a balloon for in-vivo simulation, and the outer side of the balloon for in-vivo simulation is sleeved with balloon for body surface simulation. The simulation device has the advantages that relevance three-dimensional movement of the chest wall body surface and in-vivo tumor generated when a human body breathes is represented, an accurate movement model is provided for breathing tracking and positioning research of tumor radiotherapy, and the accurate positioning function of breathing motion compensation on the image-guided radiation therapy.

The invention provides a kit for detecting serum amyloid A content and a preparation method and detection method thereof and belongs to the field of medical detection. The kit comprises a hemolytic agent R1 and a latex reagent R2 which are independent with each other. The latex reagent R2 comprises latex coated with a serum amyloid A antibody. The latex coated with the serum amyloid A antibody isprepared from latex having particle sizes of 60-130nm and coated with the anti-serum amyloid A1 antibody and latex having particle sizes of 190-220nm and coated with the anti-serum amyloid A2 antibodythrough mixing. The invention also provides a preparation method and a detection method of the kit for detecting serum amyloid A content. The kit can detect whole blood, serum, a cerebrospinal fluidand a pleuroperitoneal fluid, utilizes a small amount of samples, is free of separation or pretreatment, can be directly used for detection and has good sample compatibility.

The invention provides a wireless transmission type pleuroperitoneal minimally-invasive device carrying with an OCT technology, and belongs to the technical field of medical treatment and public health. The wireless transmission type pleuroperitoneal minimally-invasive device is characterized in that a wireless emitting device is installed in a pleuroperitoneal minimally-invasive endoscope device, image information obtained by an endoscope head sensor through the OCT technology is transmitted to a wireless receiver in a display screen viewed by an operator in a wireless mode, the output end of the wireless receiver is connected with the input end of the display screen, and therefore the image information can be displayed by the display screen; the wireless emitting device in the display screen transmits display information to a remote computer, wireless type high-frequency ultrasonic knives capable of entering from different minimally-invasive openings are arranged for selecting operation. The wireless transmission type pleuroperitoneal minimally-invasive device carrying with the OCT technology has the advantages that miniaturization is conducted on the wireless transmission type pleuroperitoneal minimally-invasive device, and carrying is convenient; meanwhile, an OCT system is integrated, minimally-invasive operation instruments used in hospital operations currently can be carried to a rescue and treatment site from hospitals, the advanced minimally-invasive operation instruments can be applied to remote areas and field sites without alternating current power supply, and application of on-site rescue and treatment is achieved.

The invention discloses an external application drug for treating pleuroperitoneal fluid and a preparing method thereof. The external application drug is prepared from, by weight, 20-30 parts of radix astragali, 20-30 parts of radix et rhizoma rhei, 10-20 parts of polyporus, 10-20 parts of rhizoma alismatis, 5-15 parts of pericarpium arecae, 5-15 parts of mirabilite, 5-15 parts of rhizoma atractylodis macrocephalae, 4-12 parts of cortex magnoliae officinalis, 4-12 parts of fruit of immature citron, 4-12 parts of semen lepidii, 2-8 parts of radix phytolaccae, 2-8 parts of seed of bunge pricklyash, 2-8 parts of semen pharbitidis and 0.5-1.5 parts of radix kansui. The common traditional Chinese medicinal materials are adopted as raw materials, the formula is scientific, cost is low, using is convenient, the treatment effect is remarkable, no side effect is caused, relapse can not occur, the functions of purgating heat and bowels, inducing diuresis and excreting dampness, removing blood stasis and stimulating the menstrual flow, relieving stagnant Qi and removing qi stagnation and tonifying spleen and kidney are realized, and pleuroperitoneal fluid can be effectively treated.

The invention relates to a novel multifunctional pleuroperitoneal cavity drainage tube which comprises a double-cavity drainage tube formed by a main drainage tube and an auxiliary drainage tube. Thecross sections of the main drainage tube and the auxiliary drainage tube are semicircular; the main drainage tube and the auxiliary drainage tube are attached together back to back to form the double-cavity drainage tube with a round cross section, the tail ends of the main drainage tube and the auxiliary drainage tube are separated and are both provided with fasteners, and a flow rate control valve is arranged at the tail end of the main drainage tube. The double-cavity drainage tube is provided with a conical air bag. By utilizing the double-cavity drainage tube, the situation can be avoidedthat a single-cavity drainage tube needs to be re-punctured and replaced due to blockage of the single-cavity drainage tube, pain of a patient is relieved, and workload of medical staff is relieved;continuous drainage is executed through the main drainage tube, and continuous flushing or medicine injection is executed through the auxiliary drainage tube; after the conical air bag is expanded, the conical air bag can be tightly attached to the skin, exudate at a wound can also be prevented from seeping outward; the flow rate control valve can control the drainage speed. The novel multifunctional pleuroperitoneal cavity drainage tube is simple in structure, low in cost, convenient to use, good in fixation, controllable in flow rate, convenient for washing and medicine injection, small in trauma to patients and free of repeated drainage bag replacement.

As an FAM19A4 protein is possibly related to various physiological and pathological conditions and plays an important role in the physiological and pathological conditions, and quantitative detectionof the soluble FAM19A4 protein in specific samples such as blood, body fluid and cell culture supernatant has significance. The invention firstly relates to an application of the FAM19A4 protein serving as a diagnosis marker of a disease including an infectious disease and an autoimmune disease. The invention further relates to a method and kit for quantitatively detecting the soluble FAM19A4 protein. According to the method and kit, the soluble FAM19A4 protein is detected through a micro-sphere solid carrier and a flow cytometry technique by the aid of the double-antibody sandwich method principle, and the method and kit can be used for quantitatively detecting the FAM19A4 protein in body fluids such as serum, plasma, urine, pleuroperitoneal fluids, joint fluids, cerebrospinal fluids, amniotic fluids and follicular fluids of a clinic patient, basic research and various biological samples such as cell culture fluids and mouse blood in a mouse model.

The invention provides an immunomagnetic head negative enrichment method and an application thereof. The method comprises the following steps: obtaining a separating medium from a pretreated pleuroperitoneal fluid sample, balancing, and centrifuging to remove deposited red blood cells; performing adsorption reaction on supernatant liquid and magnetic beads; centrifuging, balancing all liquid deposited on the magnetic beads by using a hCTC buffer solution, and then placing on a magnetic frame to adsorb the magnetic beads; centrifuging, then collecting supernatant liquid, and balancing the supernatant liquid by using the hCTC buffer solution; centrifuging to remove the supernatant; and counting cells, diluting, smearing and drying, and then performing FISH (Fluorescence In Situ Hybridization) detection. By combining the FISH detection, the method provided by the invention can improve the sensitivity and specificity of tumor cell enrichment, and is used for differential diagnosis of benign and malignant pleuroperitoneal fluid, dynamic gene detection of solid tumors, thereby realizing individualized treatment.

The invention discloses a multifunction thoracic and abdominal cavity puncturing device, which comprises a trocar for the thoracic and abdominal cavity puncturing. The trocar is connected with a drainage system for liquid drainage and also connected with an injector for injecting medicines. A first valve for controlling the breakover of the trocar and the drainage system is arranged between the trocar and the drainage system. A second valve for controlling the breakover of the trocar and the injector is arranged between the trocar and the injector. The multifunction thoracic and abdominal cavity puncturing device has reasonable structure, is easy to be grasped in operation, can be applied to aspects such as thoracocentesis drawing liquid, thoracic cavity washing, thoracocentesis air suction, thoracic cavity medicine injection, abdominocentesis drawing liquid and abdominal cavity washing , abdominal cavity medicine injection, etc.

The invention provides a method for mass production of a tissue or cell chip. The method comprises shaping tissue particles, cultured cells or collected exfoliated cells (such as pleuroperitoneal fluid exfoliated cells) through a shaping device. The tissue particles are obtained through smashing fresh tissue, tissue fixed by formalin or other solvents (such as alcohol), or paraffin-embedded tissueblocks through a tissue blender. The shaped tissue or cells are implanted into a receptor wax mold or are bonded to a metal plate and then are sliced so that a tissue or cell chip is obtained. The method has the advantages of low cost, convenience, rapidity, mass production and variety of shapes, can be used for exfoliated cells of fresh tissue, fixed tissue, paraffin-embedded tissue and cultureor pleuroperitoneal fluid, and can be spread to every pathology and related research unit.

The invention discloses a reinforced-fixed temperature measuring pleuroperitoneal cavity drainage tube, which comprises a drainage tube body, a temperature sensor, a temperature sensing line, a temperature detector, fixed airbags, gas injection paths and check valves, wherein side holes are formed in the first part of the drainage tube body; the temperature sensor is arranged on a first scale position of a second part of the drainage tube body; the temperature sensing line is connected to the temperature sensor and the temperature detector; and the temperature sensing line and the drainage tube body are closely stuck. The reinforced-fixed temperature measuring pleuroperitoneal cavity drainage tube provided by the invention, when achieving a drainage function, can synchronously conduct continuous and accurate deep temperature monitoring, and the drainage tube can be fixed in a reinforced mode; two treatment monitoring purposes can be achieved by implementing operations once; and the drainage tube can be effectively prevented from getting fallen.

The invention discloses an incision expander for a pleuroperitoneal cavity operation, which includes a left half body, a right half body and a double-hole connecting piece, wherein the right half body includes a right half body front assembly and a right half body rear assembly; the left half body, the right half body and the double-hole connecting piece form a controllable four connecting-rod structure by four pin shafts; the shape of the four connecting-rod structure can be changed when a handle is pressed, and the four connecting-rod structure is stable when shaped like a triangle, and an expansion piece for connecting the left half body and the front side of the right half body front assembly is at the maximum opening degree at the time. The incision expander has the automatic locking and closing functions, can be opened or locked when a surgeon exerts pressure, and can be closed when the surgeon continues to exert pressure, so that the operation is very convenient; the structure is simplified, the production cost is reduced, cooperation of all parts is reasonable, tiny parts are not involved, and the service life is long.

The invention discloses a tip reinforcing type pleuroperitoneal cavity drainage tube, comprising a drainage tube, wherein a tube body of the drainage tube is provided with scales; and the inner layer of the tip of the drainage tube is welded with one layer of a plastic gasket. The tip reinforcing type pleuroperitoneal cavity drainage tube is safe and reliable, and successfully solves the problem that a puncture force is greater than a tip opening closing force; and the hidden danger that a puncture needle carelessly huts human body organs is avoided. The working efficiency is improved; and the puncture needle is firmly fixed by a reinforced type tip opening and a user can accurately and effectively use according to the scales on the tube body of the pleuroperitoneal cavity drainage tube.

The invention provides a method for cultivating and separating tumor-specific TIL cells. The method comprises the following steps: step 1, obtaining tumor cell clusters and immune cell sap in pleuroperitoneal fluids; step 2, performing tumor organoid culture on the tumor cell clusters; step 3, performing amplification culture on immune cells; step 4, treating tumor organoid obtained by culture into single cells, and co-culturing the single cells and the immune cells subjected to amplification culture; and step 5, separating a specific immune cell population in the co-cultured cells. According to the method disclosed by the invention, tumor organoids and the tumor-related immune cells are simultaneously separated and cultured by utilizing the sample from the same source, and then the tumor organoids and the immune cells are co-cultured, so that the obtained tumor-specific TIL cells can keep the biological effect of the organoids, the quantity is large, and the culture period is obviously shortened. In addition, the TIL cells separated and cultured by the method are higher in tumor specificity, so that the tumor killing activity is higher.

The pleuroperitoneal cavity puncturing, tube setting and draining device includes a steel core and a double-layered jacketed sleeve with crinkle and compression preventing thread. The steel core is set inside the jacketed sleeve and has its end exposed beyond the sleeve; and the jacketed sleeve has ring arranged holes in the position of 1-2 mm to its head and is provided with rubber pipe communicated with the sleeve cavity. The device of the present invention is used to complete the operation of puncturing pleuroperitoneal cavity, setting tube and draining in one operation and greatly raised work efficiency while avoiding the damage to deep tissue and minimizing the infection.

The invention relates to the technical field of medical instruments, in particular to a malignant pleuroperitoneal effusion perfusion treatment device. Comprising a moving assembly, a base, a filling module, a hose, a supporting frame, an adjusting cylinder, a driving assembly, a gear, a rack and a traction assembly, the adjusting cylinder is arranged on the supporting frame, the driving assembly is fixedly connected with the adjusting cylinder, the gear is fixedly connected with the driving assembly, and the traction assembly comprises a connecting block, a connecting ring, a traction rope and a sleeving ring; the connecting ring is fixedly connected with the connecting block, the sleeving ring is arranged on the outer side wall of the hose in a sleeving mode, one end of the traction rope is fixedly connected with the connecting ring, the other end of the traction rope is fixedly connected with the sleeving ring, the connecting ring and the sleeving ring are connected through the traction rope, the hose is restrained under the traction force of the traction rope, and restraining of the hose is achieved; the situation that in the treatment process of a patient, the shape of the hose is changed at will, treatment operation of medical staff is affected, and the treatment progress is affected is avoided.

The invention belongs to the technical field of pleuroperitoneal cavity effusion drainage tubes, and particularly relates to a pleuroperitoneal cavity effusion drainage tube blockage prevention device which comprises a main body and a motor for transmission, the side end of the main body is connected with a drainage tube, one end of the motor is connected with a drainage tube, and one end of a transmission shaft is connected with an outer end motor through connection. One end of the main body is provided with a transmission shaft, the other end of the main body is connected with a spiral blade in a sleeved mode, the transmission shaft and the spiral blade are driven to rotate through transmission of a motor, the spiral blade stirs and disperses accumulated liquid through a cutting blade, and the situation that the interior of the drainage pipe is blocked due to accumulation of the accumulated liquid is effectively prevented. The position is driven by a limiting block motor to drive a transmission rod to rotate, the transmission rod drives the piston to slide at the position of the transmission rod through threads, and therefore the circular block and the buffering leather cushion are driven to slide, pressure is applied to the drainage tube, and hydrops in the body of a patient is led out.

The invention relates to an improved pleuroperitoneal cavity puncture needle. The puncture needle comprises a steel needle, an isolation plug is arranged at one end of the steel needle; an adjusting section is arranged at one end of the isolating plug; limiting protrusions are arranged on two sides of the adjusting section; an adjusting ring is arranged on the outer peripheral surface of the adjusting section; a limiting groove is formed in the inner wall of the adjusting ring; the limiting groove is matched with the limiting bulges; a fixing sheet is arranged on the adjusting ring; the periphery of the steel needle is sleeved with a hose; and the outer side wall of the steel needle is attached to the inner side wall of the hose. The improved pleuroperitoneal cavity puncture needle has theadvantages of effectively reducing puncture injuries, having good comfort degree, and being convenient to fix and adjust puncture length. The whole process can be completed by only one medical worker, so that time and labor are saved. The improved pleuroperitoneal cavity puncture needle can serve as a novel puncture and drainage tool and has a wide application prospect in clinical popularization.

The invention, relating to the field of medicine, discloses an externally used plaster, i.e. bupleunum-Fructus Aurantii Immaturus-Radix Curcuma-buckwheat plaster for treating hepatic cirrhosis and pleuroperitoneal fluid. The externally used plaster is a pure traditional Chinese medicine, comprising bupleunum, Radix Curcuma, Fructus Aurantii Immaturus, semen pharbitidis, rhizoma alismatis, bottle gourd peel, edible fungus, buckwheat, pseudo-ginseng, forsythia, ganoderma lucidum, white sugar, cape jasmine, red peony root, safflower, etc., is mainly used for treating hepatic cirrhosis and pleuroperitoneal fluid and preventing hepatic cirrhosis at early stage, and has the effects of promoting qi-circulation, alleviating water retention, softening liver, and invigorating spleen. The externally used plaster has the advantages of no toxic or side effect, good therapeutic effect, convenient usage, and low cost, and is an ideal medicine for treating and preventing hepatic cirrhosis and pleuroperitoneal fluid.

The invention discloses a human body pleuroperitoneal cavity three dimensional breathing motion analogue device. A rotation disc 1, a rotation disc 2 and a rotation disc 3 drive a drift angle rod 1, a drift angle rod 2 and a drift angle rod 3 with same angular velocity through rotation; a connection rod 1, a connection rod 2 and a connection rod 3 drive a tumor simulation block to generate three-dimension movement; a guiding rod 1, a guiding rod 2 and a guiding rod 3 which are fixedly connected inside an arc groove 1, an arc groove 2 and an arc groove 3 are driven to rotate along with the corresponding rotation disc with the same angular velocity under the driving of the corresponding rotation disc; the guiding rod 1 and the guiding rod 2 pushes a chest wall simulation block to horizontally move along the X direction and the Y direction through corresponding groove rod and forked tail; and the guiding rod 3 enables the chest wall simulation block to vertically move along the Z direction through pushing the support plate. The human body pleuroperitoneal cavity three dimensional breathing motion analogue device can simulate the relevance three-dimension movement between the chest wall and the tumor during the breathing of the human body, provides original data to the accurate breathing tracking and can also be used as a test platform to verify the effectiveness of the breathing tracking scheme.

The invention relates to a body model device and method for detecting navigation accuracy of a choledochoscope. The device comprises a phantom main body, wherein the phantom main body is provided witha pleuroperitoneal cavity and an operation window, the operation window communicates with the pleuroperitoneal cavity and is used for the choledochoscope to enter the pleuroperitoneal cavity, a plurality of label mechanisms are arranged on the phantom main body and are used for image registration, multiple positioning posts are arranged in the pleuroperitoneal cavity, one end of each positioningpost is connected to an inner wall of the pleuroperitoneal cavity, target ends are arranged at the other ends of the positioning posts, and graduations are arranged on the positioning posts. The bodymodel device and method for detecting navigation accuracy of the choledochoscope can be used for detecting and comparing accuracy of various navigation methods, and the clinical safety, stability andeffectiveness of various navigation methods is evaluated.

The invention discloses application of asiatic acid or a salt thereof and an injection suspension and a preparation method of the asiatic acid and the salt thereof. The application refers to application of the asiatic acid or the salt thereof to preparation of a medicament for preventing or treating body cavity adhesion. A formula of an injection suspension of the asiatic acid or the salt thereof comprises 0.5-10 percent of asiatic acid or the salt thereof, 0.1-1 percent of a suspending aid, 0.01-0.1 percent of a wetting agent, 0.0-5 percent of a preservative and the balance of water for injection, wherein the percentage refers to the mass percentage of each component in the total amount of the injection suspension. The injection suspension of the asiatic acid or the salt thereof can be used for effectively preventing or treating adhesion of body cavities including chest cavities, abdominal cavities, pleuroperitoneal cavities or joint cavities, and has a good wound healing effect.

The invention provides an external indentation positioning method for pleuroperitoneal fluid, which adopts an external indentation positioning patch for pleuroperitoneal fluid, the indentation positioning patch is attached to the skin surface, pleuroperitoneal fluid can be accurately positioned through the indentation positions of two imprinting rods. The positioning method provided by the invention is simple and practical, the positioning is noninvasive, will not bring any pain to a patient, and can avoid cross infection effectively.

The invention provides a protein chip for rapid detection of pleuroperitoneal carcinoma cells and a preparation method of the protein chip, and relates to the technical field of biomedicine. Accordingto the protein chip for rapidly detecting the pleuroperitoneal carcinoma cells and the preparation method of the protein chip, the protein chip comprises a glass slide, the glass slide is divided into a plurality of micro-array areas in a square array mode, and carboxyl magnetic beads are attached to the interior of each micro-array area. According to the protein chip for rapid detection of pleuroperitoneal carcinoma cells and a preparation method of the protein chip, carboxyl magnetic beads are attached to a glass slide; meanwhile, the carboxyl magnetic beads and the colloidal gold labeled antibody are subjected to crosslinking; the carboxyl magnetic beads and the colloidal gold labeled antibodies are subjected to cross-linking, and the sample application is performed in each micro-arrayregion, so that the colloidal gold labeled antibodies can be contained in each micro-array region, and the thoracic and ascites cancer cell detection precision can be effectively improved in the useprocess.