Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Application of asiatic acid or salt thereof and injection suspension and preparation method thereof

A technology of asiatic acid and suspensions, which is applied in the direction of medical preparations containing active ingredients, pharmaceutical formulas, emulsion delivery, etc., and can solve the problem of no reports on the prevention and treatment of body cavity adhesions, no obvious curative effect, and unusable films, etc. problem, to achieve a good wound healing effect

Inactive Publication Date: 2012-10-31
SHANGHAI INST OF PHARMA IND
View PDF1 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In the prior art, some oral preparations are used to treat body cavity adhesions, but there is no obvious curative effect; at the same time, in view of the special disease of body cavity adhesions, film preparations cannot be used, so it is urgent to develop related drugs that can effectively treat body cavity adhesions
[0003] It is reported in the prior art that asiatic acid and its salts can prevent and treat fibrosis diseases of some internal organs, but there is no report on the prevention and treatment of body cavity adhesions

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Application of asiatic acid or salt thereof and injection suspension and preparation method thereof
  • Application of asiatic acid or salt thereof and injection suspension and preparation method thereof
  • Application of asiatic acid or salt thereof and injection suspension and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030]

[0031] Preparation method: according to the above formula, use a mortar to grind and mix asiatic acid or its salt with a wetting agent, then mix evenly with suspending agent, preservative and water for injection, and then grind. Wherein, the particle size of the grinding is 0.1 μm.

Embodiment 2

[0033]

[0034] Preparation method: according to the above formula, use a mortar to grind and mix asiatic acid or its salt with a wetting agent, then mix evenly with suspending agent, preservative and water for injection, and then grind. Wherein, the particle size of the grinding is 0.3 μm.

Embodiment 3

[0036]

[0037] Preparation method: according to the above formula, use a mortar to grind and mix asiatic acid or its salt with a wetting agent, then mix evenly with suspending agent, preservative and water for injection, and then grind. Wherein, the particle size of the grinding is 0.3 μm.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses application of asiatic acid or a salt thereof and an injection suspension and a preparation method of the asiatic acid and the salt thereof. The application refers to application of the asiatic acid or the salt thereof to preparation of a medicament for preventing or treating body cavity adhesion. A formula of an injection suspension of the asiatic acid or the salt thereof comprises 0.5-10 percent of asiatic acid or the salt thereof, 0.1-1 percent of a suspending aid, 0.01-0.1 percent of a wetting agent, 0.0-5 percent of a preservative and the balance of water for injection, wherein the percentage refers to the mass percentage of each component in the total amount of the injection suspension. The injection suspension of the asiatic acid or the salt thereof can be used for effectively preventing or treating adhesion of body cavities including chest cavities, abdominal cavities, pleuroperitoneal cavities or joint cavities, and has a good wound healing effect.

Description

technical field [0001] The present invention relates to the application of asiatic acid or its salt, its injection suspension and its preparation method. Background technique [0002] Body cavity adhesion (same as "adhesion") is a complication that is prone to occur after surgery or bacterial inflammation, generally including abdominal cavity, chest cavity, joint cavity and other body cavity adhesions. In the prior art, some oral preparations are used to treat body cavity adhesions, but there is no obvious curative effect; at the same time, in view of the special disease of body cavity adhesions, film preparations cannot be used, so it is urgent to develop related drugs that can effectively treat body cavity adhesions. [0003] It is reported in the prior art that asiatic acid and its salts can prevent and treat some fibrotic diseases of internal organs, but there is no report on the prevention and treatment of body cavity adhesions. Contents of the invention [0004] The...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/56A61K9/10A61P41/00
Inventor 刘英刘全海陆伟根刘珉宇黄晓玲张瑱肖璘蔡立吴学军陈亭亭
Owner SHANGHAI INST OF PHARMA IND
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com