54 results about "Intestine obstruction" patented technology

The invention discloses an anti-winding intestinal obstruction catheter system and method. The anti-winding intestinal obstruction catheter system comprises a handle, a catheter body and a rigidity adjusting device. The catheter body is a flexible body, the near end of the catheter body is connected with the handle, and the far end of the catheter body is provided with a balloon and a charging pipeline communicated with the balloon; the rigidity adjusting device is connected with the catheter body and used for adjusting the bending rigidity of the catheter body after the catheter body is placed into the duodenum. The anti-winding intestinal obstruction catheter system is adopted in the catheter indwelling method of the anti-winding intestinal obstruction catheter, and the anti-winding intestinal obstruction catheter system and method can effectively prevent the catheter from being wound, improve the catheter indwelling success rate and ensure the operation safety at the same time.

The invention relates to a magnetic control self-conformal intestinal stent and a dynamic monitoring system, and belongs to the technical field of medical instruments, and the magnetic control self-conformal intestinal stent comprises a biodegradable main skeleton, a magnetic driving unit, a pressure sensing array and an in-vitro control device. A magnetic response material is embedded into the main framework, and form regulation and control and degradation rate control are realized through an in-vitro magnetic field; the flexible sensing array monitors intestinal wall pressure in real time, and the self-adaptive structure is linked to dynamically adapt to the intestinal tract curved surface. The in-vitro device integrates magnetic field adjustment and data processing, and supports precise positioning of the support and intelligent adjustment of the attaching force. The system improves the stability in a complex intestinal environment through magnetic coupling driving and multi-mode monitoring, early warns abnormal risks in real time, and avoids the rigid defect and monitoring lag problems of a traditional stent. The biodegradable material is combined with intelligent control, the degradation process and tissue repair are synchronized, a safe and effective treatment scheme is provided for diseases such as intestinal obstruction, and the treatment effect of a patient is improved.

The present invention complies with the technical field of intestinal obstruction catheters, and in particular relates to an intestinal obstruction catheter with a visual camera. It comprises a catheter body, the catheter body is fixedly connected to a guide head, the guide head is provided with circumferentially spaced visual cameras, the catheter body is provided with a suction channel, a reserved channel 1 and a reserved channel 2, the catheter body is provided with spaced suction holes, the catheter body is provided with a liquid sac 1, the liquid sac 1 is connected to a catheter 1, the visual camera is connected to a data cable, the data cable is located in the reserved channel 2, and the tail end of the catheter body is provided with a liquid injection port 1, a data plug and a guide wire inlet. The present invention utilizes circumferentially equally spaced visual cameras to timely observe the internal environment of the intestinal cavity and the intestinal lesions, and at the same time, does not require an endoscope to be lowered into the intestinal cavity along with the catheter body, thereby reducing the discomfort of the patient's esophagus and throat after surgery.

The intestinal obstruction catheter kit comprises a catheter, a balloon, a medicine supply connector, a suction connector and an air inlet connector, the catheter is provided with a suction cavity channel, a medicine supply cavity channel and an air inlet cavity channel, the suction cavity channel, the medicine supply cavity channel and the air inlet cavity channel extend in the length direction of the catheter, the suction cavity channel and the medicine supply cavity channel are isolated, and the air inlet connector is connected with the balloon. The balloon is sleeved on the catheter and communicated with the air inlet cavity, the medicine supply connector is connected to the catheter and communicated with the medicine supply cavity, the suction connector is connected to the catheter and communicated with the suction cavity, the air inlet connector is connected to the catheter, and the air inlet connector is communicated with the air inlet cavity. The medicine supply cavity channel is arranged in the catheter and is isolated from the suction cavity channel, so that the problem of clinical cross infection can be solved. The intestinal obstruction catheter kit supports administration aiming at intestinal obstruction conditions and suction treatment of foreign matters at the same time, and is beneficial to accurately, safely and quickly solving the problem of intestinal obstruction.

The invention relates to the technical field of medical instruments, in particular to an intestinal obstruction catheter anti-reflux drainage device. The device comprises a three-way connector, a first drainage catheter communicated with a port in one end of the three-way connector, a spiral drainage tube communicated with a port in one end of the three-way connector, a one-way valve communicated with a port in one end of the three-way connector and a multi-cavity collection bag communicated with the spiral drainage tube. A plurality of elastic valves are arranged on the inner tube wall of the first drainage catheter in the circumferential direction of the first drainage catheter, each valve is provided with a pair of side edges and a lower edge, and the lower edges of the valves are fixedly connected with the inner wall of the first drainage catheter. According to the intestinal obstruction catheter anti-reflux drainage device, the problems that in existing intestinal obstruction drainage, intestinal contents in a drainage tube are prone to reflux, and the reflux solving operation is tedious are solved.

The invention discloses a full-degradable intragastric balloon and a preparation method thereof, and relates to the technical field of medical instruments. The intragastric balloon is of a double-layer composite structure, the outer layer of the balloon is an alkali response gel film, and the inner layer of the balloon is an acid response polymer film; the alkali response gel film is a PVA-boric acid gel film, and the acid response polymer film is polymethacrylate resin. The dual pH response mechanism ensures that the damaged balloon is not detained in the intestinal tract for a long time, and the risk of causing intestinal obstruction is reduced. Therefore, the safety of the intragastric balloon is improved, and the active safety design concept that the function can be maintained and the failure can be degraded is achieved.

The invention relates to the technical field of medical nutrition preparations, in particular to an enteral nutrition composition for patients with lymph node injury chylomile leakage, and 100g of the composition comprises the following components: 15-30g of compound oligopeptide powder, 35-80g of carbohydrate, 5-15g of fat, 3-5g of glutamine, 0.1-2g of multivitamins, 0.05-1g of trace elements, 2-4g of electrolyte, 0.1-0.3 g of food additives and 109-1011CFU of probiotics. The composition well solves the problems of inaccurate intestinal nutrition support, low absorption and utilization rate, lack of functional regulation components and the like of incomplete intestinal obstruction tumor patients.

The application provides a multifunctional intestinal stent and a preparation method thereof. The multifunctional intestinal stent comprises, from outside to inside, an anti-tumor layer, a load-bearing layer and an anti-stenosis layer. The anti-tumor layer comprises an outer layer and an inner layer, wherein the outer layer is a nanofiber membrane containing MXene, and the inner layer is a composite membrane containing a chemotherapeutic drug, and the inner layer is in contact with the outer side of the load-bearing layer. The load-bearing layer is a tubular stent obtained by 4D printing of a shape memory polymer material. The anti-stenosis layer contains triprolidine. The multifunctional intestinal stent provided by the application can not only rapidly and continuously treat intestinal obstruction caused by space-occupying tumors, but also facilitate coordinated deformation, reduce tissue abrasion, and has an anti-restenosis function, so as to better maintain normal intestinal function.

The present invention relates to 1-isopropyl-2-oxo-1,2-dihydroquinoline-3-carboxylic acid {(1S,3R,5R)-8-[(R)-2-hydroxy-3-(methanesulfonyl-methyl-amino)propyl]-8-azabicyclo[3.2.1]oct-3-yl}amide (velcetrag) or a pharmaceutically acceptable salt thereof for use in the treatment of idiopathic chronic intestinal pseudo-obstruction (CIPO), neuropathic chronic intestinal pseudo-obstruction, or chronic intestinal pseudo-obstruction secondary to a neurodegenerative or demyelinating condition in patients suffering from said disease or condition.

The present invention relates to methods and materials for treating diseases, disorders, and / or conditions associated with elevate lipase levels and / or activity. Diseases, disorders, and / or conditions can be selected from intestinal obstruction, spontaneous bacterial peritonitis, or cirrhosis, and / or one or more diseases, disorders, and / or conditions worsened by a pancreatic injury in a mammal (e.g., a human). For example, methods for using one or more lipase inhibitors to treat a mammal having or at risk of developing intestinal obstruction are provided.

The invention relates to the technical field of intestinal obstruction catheters, and particularly discloses a novel intestinal obstruction catheter placed through abdominal wall-stomach fistulization, the novel intestinal obstruction catheter comprises a cannula, an abdomen and a stomach, one end of the cannula penetrates through the abdomen and the stomach under the guidance of a gastroscope, a first fixing mechanism is arranged at one end of the cannula, and a first through hole and a second through hole are formed in the cannula; a catheter body and a nutrient canal are installed in the first through hole and the second through hole respectively, a fixing end is installed at the other end of the cannula, a connecting opening is formed in one end of the catheter body, and a sheath tube is inserted in the connecting opening. According to the intestinal obstruction catheter, the cannula is directly installed in the stomach of a patient, and then the catheter body penetrates through the cannula and is placed in the intestinal tract of the patient, so that the situation that the catheter body directly penetrates through the nostril-esophagus of the patient to cause great pain to the patient, especially the patient needing to place the intestinal obstruction catheter for a long time, is avoided; and the catheter body is matched with the nutrition tube, so that nutrition can be conveniently supplied to the intestines, and the malnutrition condition of the patient is avoided.

The invention relates to the technical field of medical instruments, in particular to a split intestinal obstruction catheter device with a nutrition supporting function. The device comprises a drainage tube, a connecting branch tube arranged at the rear end part of the drainage tube in a communicating manner, a nutrient tube of which the front end penetrates through the connecting branch tube and is movably arranged in the drainage tube, and a locking piece which is fixedly arranged on the connecting branch tube and is used for locking the nutrient tube. The invention aims to provide a split intestinal obstruction catheter device with a nutrition support function.

This invention discloses an intelligent enema device for elderly patients with incomplete intestinal obstruction, belonging to the field of medical device technology. It includes a collection box with a constant temperature control system on its inner wall, a U-shaped dispensing tube fixedly connected to the top, and an infusion tube fixedly connected to the outer wall of the dispensing tube. The top of the infusion tube is detachably connected to an insertion tube via a connector. A switching component is provided on the outer wall of the dispensing tube. The switching component enables rapid switching between single-tube infusion and gas delivery paths. The constant temperature control system ensures stable enema fluid temperature through multi-node temperature detection, precise PID adjustment, and an all-around insulation structure. It also features convenient assembly and disassembly, safety alarms, and other functions, reducing the complexity of medical operations and improving treatment efficiency and safety. It is suitable for clinical enema treatment of elderly patients with incomplete intestinal obstruction.

The utility model discloses a kind of intestinal obstruction surgery intestinal tract dredging drainage structures, it is related to medical equipment technical field, including colon, the right side of the colon is fixedly installed with fixed component, the right side of the fixed component is fixedly installed with connecting component, the right side of the connecting component is fixedly installed with connector, the right side of the connector is fixedly connected with conveying pipe.The utility model said a kind of intestinal obstruction surgery intestinal tract dredging drainage structures, by rotating annular mounting plate, annular mounting plate can be rotated and clamped into the inside of two limit arc clamping plate, limit column is ejected under the action of spring and is clamped in the arc limit slot of annular mounting plate at this time, to be limited and fixed on the bottom disc under the action of limit arc clamping plate, simultaneously annular plate, pull rod can pull limit column and move back into the inner cavity of fixed sleeve, to be able to rotate and take down annular mounting plate, to be convenient for quick installation and fixed and disassembly when using.

The invention relates to a traditional Chinese medicine composition for treating qi-stagnation and body fluid deficiency and blood-deficiency dampness loss type intestinal pseudoobstruction, which can effectively solve the medication problem of the qi-stagnation and body fluid deficiency and blood-deficiency dampness loss type intestinal pseudoobstruction. The traditional Chinese medicine preparation is prepared from the following traditional Chinese medicine raw materials by weight: radix asteris, semen raphani, fructus aurantii, radix rehmanniae, herba cistanche, angelica sinensis, peach kernels, fructus cannabis, rhizoma cimicifugae and liquorice, and is prepared by soaking the raw materials in water, boiling with strong fire, decocting with slow fire, filtering and concentrating. The traditional Chinese medicine composition disclosed by the invention is matched and mutually supported according to a main and secondary relationship of monarch, minister, assistant and guide, is scientifically prepared, has the effects of promoting qi circulation, nourishing yin, nourishing blood and moistening intestines, is convenient to take and good in effect, is a new breakthrough in medicines for treating qi stagnation, fluid deficiency and blood deficiency type intestinal pseudoobstruction, and has practical popularization and application values.

The invention discloses a gastric-soluble fiber material applied to infant and pet supplies and a preparation method of the gastric-soluble fiber material. The gastric-soluble fiber material comprises the following components in parts by weight: 100 parts of polymethacrylate; 5-10 parts of a plasticizer; due to the solubility of the gastric-soluble fiber material in a gastric acid environment, the products made of the gastric-soluble fiber material and applied to various infants and pets have necessary solubility, and when the products are possibly bitten, torn and damaged by the infants or pets, the products can not be damaged by the infants or pets. When the gastric juice is completely dissolved in the stomach, the gastric-soluble fiber material can react with hydrochloric acid in the gastric juice after a product made of the gastric-soluble fiber material generates fragments or the fiber body serving as a filler leaks and is eaten by mistake, so that the gastric-soluble fiber material is gradually dissolved into a flocculent or gelatinous state and is finally completely dissolved in the stomach environment; the intestinal obstruction condition caused by aggregation of common material fragments or fibers serving as fillers in intestines and stomachs can be avoided, and the safety of various infant and pet supplies can be remarkably improved.

The invention provides an intestinal obstruction soft robot control method and system and a storage medium, when a soft robot is guided to move along an alimentary canal to reach an obstructed intestinal cavity through a magnetic control navigation assembly, a controllable attaching assembly is controlled to be attached and fixed to an intestinal wall; controlling an environment sensing assembly to collect intestinal environment parameters of the obstructed intestinal cavity before dredging; controlling the drug sustained-release component to release the dredging drug according to the drug sustained-release dosage; controlling an environment sensing assembly to obtain intestinal environment parameters of the obstructed intestinal cavity after dredging; judging whether the obstructed intestinal cavity is smooth or not; the controllable attaching assembly is controlled to be separated from the intestinal wall, and the soft robot is guided to move along the alimentary canal through the effect of an in-vitro magnetic field till being moved out of the body. Through the combination of the soft bionic structure design and the magnetic field remote control technology, precise positioning and attaching, local medicine slow release and state monitoring feedback of the soft robot are achieved, closed-loop control of propelling, attaching, sensing, slow release, judging and recycling is formed, and the preoperative cleaning efficiency and operation safety of intestinal obstruction are improved.

The cancerous intestinal obstruction intervention device comprises a main drainage tube, a water bag and a body surface fixing mechanism are arranged on the main drainage tube, the water bag is arranged at the end, intervened into a patient, of the main drainage tube, and the body surface fixing mechanism is used for being matched with the water bag to fix the main drainage tube; the water bag is communicated with a plurality of jet flow mechanisms used for dredging intestinal contents based on contraction pressure of the water bag, self-adaptive switching mechanisms are arranged in the jet flow mechanisms, and the self-adaptive switching mechanisms are used for opening and closing the jet flow mechanisms based on pressure changes in the main drainage tube and switching the jet flow direction based on the pressure direction until the jet flow direction points to the blocking position. According to the scheme, the probability that the catheter is blocked can be reduced, and the smoothness of enteric cavity decompression is improved.

The utility model relates to the technical field of medical instruments, in particular to an ileum fistulization bypass catheter device. The ileum fistulization bypass catheter device comprises a first catheter body, the front end of the first catheter body is of an open structure, a plurality of first through holes are formed in the side portion of the first catheter body, and an air bag assembly is arranged on the rear section of each first through hole; a connecting port is formed in the tube tail of the first tube body, and a drainage bag is detachably connected to the outer side of the connecting port; a first branch tube communicated with the air bag assembly is arranged on one side of the tube tail of the first tube body, and an air injection valve used for injecting air into the air bag assembly or exhausting air from the air bag assembly is installed on the first branch tube, so that the function of cutting off an enteric cavity (namely air bag intestinal obstruction) is achieved, intestinal contents can be transferred through a catheter, and the risk of leakage of an anastomotic stoma is reduced. The nursing bed is easy to operate, convenient to nurse and easy to accept by patients and family members, and pain caused by treatment of the patients is greatly reduced.

The utility model relates to the technical field of medical supplies, in particular to an intestinal transnasal intestinal obstruction catheter fixing device which comprises a clamping ring, foam dressing is fixedly connected to the outer surface of the clamping ring, and pasting films are fixedly connected to the left portion and the right portion of the outer surface of the foam dressing. According to the catheter fixing device for the intestinal transnasal intestinal obstruction, the clamping ring provides a fixing function for the catheter, shaking and displacement of the catheter are reduced, it is ensured that the catheter is always kept at a stable position in the using process, the foam dressing has soft texture and good elasticity, pressure on the skin of a patient can be relieved, and the catheter is prevented from being damaged. Particularly, under the condition that the fixing device is worn for a long time, the foam dressing can effectively prevent the formation of pressure sores and improve the comfort of a patient, and meanwhile, the foam dressing can timely absorb percolate appearing around the catheter and keep the skin dry and clean, so that the risk of skin infection is reduced, and wound healing is promoted.

The present application relates to the technical field of medical devices, and discloses a real-time pressure regulating system for an intestinal obstruction catheter and the intestinal obstruction catheter. The system comprises a data acquisition module that generates a dynamic three-dimensional intestinal pressure field model, synchronously monitors intestinal PH value, oxidation-reduction potential and gas composition; an intestinal obstruction type identification module that analyzes pressure waveform characteristics and identifies the obstruction type in combination with knowledge graph reasoning; a comprehensive obstruction index output module that fuses multiple physiological data to obtain a comprehensive obstruction index; a cross-patient scheme adaptation module that adapts a cross-patient treatment scheme to obtain an initial airbag adjustment strategy; a scheme optimization and closed-loop fuzzy control module that constructs a personalized intestinal data coupling model, combines an MPC and a double closed-loop fuzzy PID controller to optimize a strategy output control instruction; and through model prediction and closed-loop control, the airbag pressure can be adjusted in real time and accurately according to the intestinal condition of the patient, dynamic and accurate control of the intestinal obstruction treatment process is realized, and the treatment effect is improved.

The invention provides a safe plush toy applied to infants or pets, which is characterized in that an outer sleeve sleeved on the surface of the safe plush toy, an internal filler and accessories on the surface of the safe plush toy are independently or jointly prepared from chitosan, polymethacrylate or polyvinyl acetal diethylamino acetate or prepared from the chitosan, the polymethacrylate or the polyvinyl acetal diethylamino acetate through modification; therefore, the outer sleeve sleeved on the surface of the safe plush toy, the inner filler and the accessories on the outer sleeve all have the dissolving property in a gastric acid environment, so that when the safe plush toy is possibly bitten, torn, damaged and mistakenly eaten by infants or pets, the safety plush toy can be prevented from being eaten by the infants or the pets. The outer sleeve arranged on the surface of the safe plush toy in a sleeving mode, the inner filler and the accessories on the surface can react with hydrochloric acid in gastric juice, so that chitosan fibers are gradually dissolved into a flocculent or gel state and finally completely dissolved in the stomach environment; the condition of intestinal obstruction caused by aggregation of common polymer fibers in intestines and stomach can be completely avoided, and the safety of the plush toy product can be obviously improved.

The utility model discloses a duckbill valve for fixing a nasointestinal obstruction catheter. Comprising a first pipeline and a second pipeline; a duckbill valve mechanism is mounted in the first pipeline; the duckbill valve mechanism comprises a threaded connecting ring, a supporting part is fixedly arranged at one end of the threaded connecting ring, and a valve port part is fixedly arranged on one side of the supporting part. The first pipeline or the second pipeline is installed through an adjustable fixing mechanism.

Provided herein is a bulk composition comprising the trihydrate form of (3S, 4R, 3′R)-6-[4-(4-amino-5-chloro-2-methoxy-benzoylamino)-3-methoxy-piperidin-1-yl]-hexanoic acid 1-azabicyclo[2.2.2]oct-3′-yl ester di-hydrochloride salt. Provided are also pharmaceutical compositions and dosage forms comprising the trihydrate form, and methods and uses for treating a gastrointestinal disorder in a subject with the trihydrate form. In some embodiments, the gastrointestinal disorder is gastroesophageal reflux disease (GERD), dyspepsia (such as functional dyspepsia or functional motility disorder), gastroparesis, paralytic ileus, post-operative ileus, emesis, nausea, heartburn, intestinal pseudo-obstruction, irritable bowel syndrome (IBS), constipation, enteral feeding intolerance (EFI), or esophagitis. In some embodiments, the gastrointestinal disorder is post-operative ileus, chronic grass sickness, constipation, megacolon, gastritis, gastrointestinal stasis, or abomasal emptying defect.

The invention discloses an intestinal obstruction catheter kit and a medical device, and relates to the technical field of medical instruments. The intestinal obstruction catheter kit comprises a first balloon catheter and a second balloon catheter, a first far-end balloon and a first near-end balloon which are spaced from each other are arranged on the outer surface of a first catheter body of the first balloon catheter, the first far-end balloon is close to the far-end end of the first catheter body, and the first near-end balloon is located at the near end of the first far-end balloon; the first far-end balloon and / or the first near-end balloon are / is used for being anchored with the intestinal wall; the outer surface of the far end of a second catheter body of the second balloon catheter is at least provided with a second far-end balloon, and the second far-end balloon is used for being anchored with the intestinal wall; the first catheter body is further provided with a first channel penetrating in the axial direction, and the first channel is used for allowing the second balloon catheter to pass through and enabling the second far-end balloon to reach the far end of the first balloon catheter. According to the intestinal obstruction catheter suite, the advancing speed of the intestinal obstruction catheter suite can be obviously increased by anchoring the balloon and the intestinal wall and then pulling the catheter back.

The present application relates to medical decompression apparatus technical field, specifically in the intestine of a kind of intestinal decompression device for use in intestinal obstruction surgery, including catheter main body, catheter main body is equipped with suction hole and front balloon, still including the movable pipe one and movable pipe two of movable setting in catheter main body, movable pipe one and movable pipe two are connected with catheter main body by elastic liquid-filled bladder, elastic liquid-filled bladder is communicated with front balloon, movable pipe one is equipped with communication hole, communication hole is misaligned with suction hole in initial state;And the fixed frame of setting in movable pipe two, fixed frame is equipped with magnetic ring two, fixed frame is slidably installed with sealing element, one side of sealing element is equipped with magnetic ring one, one side of sealing element is equipped with guide slope.The present application is pushed movable pipe one and movable pipe two by front balloon liquid filling, opens suction hole and movable pipe two to cooperate suction, when front balloon is damaged, communication hole is misaligned with suction hole, sealing element retracts and seals movable pipe two, prevent to be sucked to patient intestinal inner wall, it is safer.

The invention discloses a composite emulsion for intestinal obstruction, a preparation method thereof and application of the composite emulsion in intestinal obstruction treatment. The intestinal obstruction composite emulsion comprises the following components in percentage by weight: 10-30% of a traditional Chinese medicine extract, 60-85% of paraffin oil, 3-8% of an emulsifier and 0.5-2% of a stabilizer, and the intestinal obstruction composite emulsion is a W / O type emulsion. The invention has the beneficial effects that the lubricating effect of the traditional paraffin oil and the anti-inflammatory and detumescence effects of the traditional Chinese medicine extract are deeply fused through a nano-emulsification technology, and the core defects of single mechanism, systemic toxicity and poor targeting property of the existing therapy are overcome. According to the traditional Chinese medicine composition, the symptom remission rate can be greatly improved, inflammatory factors are obviously reduced, the curative effect is obviously improved, and safety is optimized and applicable people are expanded. The composite emulsion is expected to become a first-line choice for conservative treatment of intestinal obstruction, especially provides a new treatment hope for patients who cannot tolerate operations, and has remarkable clinical transformation value and social and economic benefits.

The utility model discloses an effusion and pneumatosis discharging device for intestinal obstruction abdominal distension of old people, which belongs to the related technical field of medical instruments and comprises a drainage box, a drainage tube and a negative pressure tube are communicated on the drainage box, a first cavity, a second cavity and a third cavity are arranged in the drainage box, the first cavity and the second cavity are communicated with the drainage tube, and the third cavity is communicated with the negative pressure tube and the second cavity. The first cavity and the second cavity are communicated through a first air guide pipe, and a first measuring cavity, a second measuring cavity and a third measuring cavity are formed in the first cavity. The drainage box with the large size is used for conducting drainage and collection on hydrops in a patient, and when the hydrops are gradually accumulated in the first measuring cavity, the second measuring cavity and the third measuring cavity in the cavities, the hydrops in the patient can be collected through the drainage box with the large size; according to the device, the proper time period is selected, the indicating assembly is used for marking the hydrops in each time period, so that the hydrops change conditions among the time periods are simple, clear and easy to observe, the data recording process is simplified, and nursing work of medical staff is facilitated.

The invention relates to 1-isopropyl-2-oxo-1,2-dihydroquinoline-3-carboxylic acid {(1S,3R,5R)-8-[(R)-2-hydroxy-3-(methanesulfonyl-methyl-amino)propyl]-8-azabicyclo[3.2.1]oct-3-yl}amide (velusetrag) or a pharmaceutically acceptable salt thereof for use in a method of treating idiopathic chronic intestinal pseudo-obstruction (CIPO), neuropathic chronic intestinal pseudo-obstruction, or chronic intestinal pseudo-obstruction being secondary to neurodegeneration or to demyelinating conditions in a patient suffering from said diseases or conditions.

This invention discloses an integrated intestinal obstruction decompression and suction scraping device, relating to the field of medical device technology. It includes a handheld main unit, a disposable suction tube, and a transparent collection bag. The tail end of the disposable suction tube is detachably connected to the front end of the handheld main unit, and the transparent collection bag is detachably installed on the side of the handheld main unit. The handheld main unit houses a drive motor, and the front end of the drive motor has a transmission shaft. This invention utilizes the dual rotational crushing and scraping functions of the scraping head and the basket-shaped scraper. When the head end of the inner spiral outer tube encounters fecal impaction, it can directly initiate rotational scraping within the intestinal lumen, breaking up the fecal impaction and suctioning it out under negative pressure. This achieves unblocking without removal from the body, avoiding mechanical damage to the intestinal wall caused by repeated insertion and removal. By integrating the crushing, suction, and scraping functions into a single device, the smoothness of the procedure is improved.