42 results about "Ileus" patented technology

Method and system to provide therapy for obesity and gastrointestinal disorders such as FGIDs, gastroparesis, gastro-esophageal reflex disease (GERD), pancreatitis and ileus comprises vagal blocking and / or vagal stimulation. Vagal blocking may be in the afferent or efferent direction, and may be with or without stimulation pulses. Blocking may be provided by one of a number of different electrical blocking techniques. Electrical signals may be provided with an external stimulator in conjunction with an implanted stimulus-receiver, or an implanted stimulus-receiver comprising a high value capacitor for temporary power source. In one embodiment, the external stimulator may comprise an optional telemetry unit. The addition of the telemetry unit to the external stimulator provides the ability to remotely interrogate and change stimulation programs over a wide area network, as well as other networking capabilities,

The present invention is directed to compositions useful in treating or preventing ileus in a patient. The compositions of the invention include a pituitary adenylate cyclase activating peptide (PACAP) receptor antagonist and / or a vasoactive intestinal peptide (VIP) receptor antagonist in an amount sufficient to treat or prevent ileus in a patient. In one embodiment both a PACAP and VIP receptor antagonists are present, preferably in a combination that blocks vasoactive pituitary cyclase 1 (VPAC1), VPAC2 and pituitary adenylate cyclase 1 (PAC1) receptors. Methods of using such composition to treat or prevent ileus in a patient are also encompassed by the invention.

A small bowel endoscopic system of an ileus tube type using a monolithic composite optical fiber that can be applied with an ileus tube employed to administer a contrast agent or the like to a patient suffering from ileus and which is an integral assembly of a large-diameter optical fiber with a core / cladding structure intended for laser light transmission and a multi-core image fiber section surrounding that optical fiber to enable image transmission.

The present invention is directed to compositions useful in treating or preventing ileus in a patient. The compositions of the invention include a pituitary adenylate cyclase activating peptide (PACAP) receptor antagonist and / or a vasoactive intestinal peptide (VIP) receptor antagonist in an amount sufficient to treat or prevent ileus in a patient. In one embodiment both a PACAP and VIP receptor antagonists are present, preferably in a combination that blocks vasoactive pituitary cyclase 1 (VPAC1), VPAC2 and pituitary adenylate cyclase 1 (PAC1) receptors. Methods of using such composition to treat or prevent ileus in a patient are also encompassed by the invention.

The present invention discloses a thermotherapeutic medicated bag for restoring gastrointestinal function after abdominal operation and its production method. It is characterized by that its composition comprises 17 Chinese medicinal materials of radish seed, unripe tangerine peel, fennel fruit, unripe bitter orange, magnolia bark and others. Said invented bag can improve local blood circulation, promote restoration of gastrointestinal function afte abdominal operation, and also can obtain obvious therapeutic effect for curing incomplete intestinal adhesion, ileus, constipation and other abdominal chronic inflammation, etc.

The invention provides an enteroclyster mixture for treating intestinal obstruction, which is prepared from magnolia bark, radish seeds, rhubarb horsetails, peach kernels, mirabilite, radix paeoniae rubrathe, immature bitter orange, banksia rose and herba patriniae through the steps of charging the medicinal materials into water, boiling three times, merging filtrate, filtering, stewing and taking the supernatant fluid, concentrating, homogenizing, finally split charging and sterilizing.

The Chinese medicine for treating intestinal obstruction is prepared with nine kinds of Chinese medicinal materials, including sena leaf, mirabilite, rhubarb, peach kernel, red peony root, etc. in certain weight proportion. It has facile materials, simple preparation process, low cost and high curative effect.

The cathartic medicine is prepared with licorice, honeysuckle, cassia obtusifolia, radish seed, skullcap root and other six kinds of Chinese medicinal materials, which are prepared into medicine powder through drying in the air or stoving, crushing, mixing in certain proportion, cooking and sterilizing. the medicine powder is taken after being mixed with boiling water to treating chronic constipation, intractable constipation, indigestion, gastritis, infantile malnutrition, ileus, etc. It has the functions of clearing away heat in the pericardium, resisting senility, regulating immunity, etc.

Solid dispersions of stable, amorphous opioid antagonists, particularly [[2(S)-[[4(R)-(3-hydroxyphenyl)-3(R),4-dimethyl-piperidinyl]methyl]-1-oxo-3-phenylpropyl]amino]acetic acid, with improved water solubility and bioavailability are disclosed. Also disclosed are methods of preventing or treating a side effect associated with an opioid. In addition, methods of treating or preventing pain, ileus, and opioid bowel dysfunction are disclosed.

The invention pertains to the use of a lipid-rich nutrition for the manufacture of a composition for the prevention and / or treatment of post-operative ileus. The lipid fraction inhibited IL-6 and TNF-α levels in peritoneal lavage fluid, and / or wherein the lipid fraction prevents influx of neutrophils in the intestinal muscularis following intestinal manipulation. The nutritional composition comprises at least a lipid fraction which accounts for 42 to 90%, preferably between 45 and 70% of the total energy of the composition. The lipid fraction preferably contains 8 to 50 wt % of phospholipids.

The invention relates to a traditional Chinese medicinal composition for treating intestinal obstruction which is prepared from the following Chinese medicinal herbs (by weight ratio): fresh ginger 10-40, bamboo shavings 9-36, root of large-flowered skullcap 6-24, white atractylodes rhizome 7-28, poria cocos wolf 6-24, rhubarb horsetails 5-20, Chinese angelica root 6-24, garden burnet root 5-20, coptis root 5-20, bupleurum root 10-40, dried orange peel 5-20, aloe 10-40, bear gall 5-20, ginseng 9-36 and cyperus tuber 6-24. The dose form includes capsules, decoctions, pills and powders.

The invention discloses an ileus dredging device which comprises a conduit, wherein a side hole is formed in the front end pipe wall of the conduit, an outer guide hole is formed in the rear end of the conduit, a pneumatic guide head is disposed on the front end of the conduit body, the pneumatic guide head comprises a pneumatic telescopic body and an elastic balloon which are connected integrally, and the elastic balloon is located on the front end of the pneumatic telescopic body; and the pneumatic telescopic body and the elastic balloon are connected to a telescopic body pipe and a balloonpipe respectively, the telescopic body pipe and the balloon pipe penetrate out from the tail part of the conduit, a telescopic body pipe joint and a balloon pipe joint used for air inflation and air deflation are disposed at the tail end of the telescopic body pipe and the tail end of the balloon pipe respectively, and the balloon pipe is an X-ray development pipe. The ileus dredging device is applied to depressurization, discharge of pneumatosis and hydrops and liquid medicine injection for an ileus patient. During use, when the conduct cannot be advanced normally due to obstruction obstacles, the pneumatic guide head can be operated to drag the conduit to advance and pass through the obstacles step by step to reach a drainage part. The flexible telescopic body pipe and the soft balloon pipe can look for clearance automatically when being inflated to extend, the passing capability is strong, the intestinal wall is not damaged, and operations are convenient, safe and reliable.

A traditional Chinese medicine for remedying the stasis type of ileus belongs to the traditional Chinese medicine for remedying the ileus. The components contain: 9g of prepared common monkshood daughter roots, 9g of parched hawthorn, 6g of Manchurian wild ginger, 15g of rhubarb, 30g of hematite, 30g of parched seeds of garden radish, 12g of orange fruits and 12g of barks of officinal magnolia. The dosage materials in the prescription are all made from natural traditional Chinese herbal medicines by the traditional processing method. The materials can be easily gotten; the prescription and the preparation method are simple; the expense for preparing the medicine is low. The compatibility of the traditional Chinese herbal medicines is simple; the medicines used in the medicine prescription are all natural herbal medicines which can be conveniently gotten and used; the manufacturing method is simple; the curative effect after being taken is good; the medicine price is cheap, and the medicine is especially fit for people who live at the remote small villages away from villages and towns to use. The treatment expense for the patient with the disease of the stasis type of ileus is low, which solves the treatment problem, which is caused by low family income, poor living and lack of local medical treatment condition.

The invention discloses a Chinese medicinal preparation for treating ileus. The Chinese medicinal preparation is prepared from following raw material medicaments in part by weight: 30 parts of aurantium fruit fructus aurantii, 10 parts of Chinese eaglewood, 10 parts of szechuan lovage rhizome, 6 parts of tsaoko amomum fruit, 15 parts of rhubarb, 15 parts of pharbitis seed and 50 parts of honey; the formulations of the Chinese medicinal preparation comprises pills, powders, oral liquid preparations and capsules manufactured by a traditional preparation process or a modern preparation process. Clinical application shows that the Chinese medicinal preparation has the advantages of rapid effect, obvious treatment effect, good tolerance, low cost and no any toxicity and side effect.

Methods for the treatment of ileus are disclosed wherein the peripheral mu opioid antagonist methylnaltrexone is administered.

A traditional Chinese medicine for remedying the paralytic ileus after the operation belongs to the traditional Chinese medicine for remedying the ileus. The components contain: 12g of dangshen, 12g of poria cocos, 9g of green tangerine peels, 15g of seeds of dwarf flowering cherry, 15g of seeds of garden radish, 6g of common aucklandia roots and 6g of senna leaves. The dosage materials in the prescription are all made from natural traditional Chinese herbal medicines by the traditional processing method. The materials can be easily gotten; the prescription and the preparation method are simple; the expense for preparing the medicine is low. The compatibility of the traditional Chinese herbal medicines is simple; the medicines used in the medicine prescription are all natural herbal medicines which can be conveniently gotten and used; the manufacturing method is simple; the curative effect after being taken is good; the medicine price is cheap, and the medicine is especially fit for people who live at the remote small villages away from villages and towns to use. The treatment expense for the patient with the disease of the paralytic ileus after the operation is low, which solves the treatment problem which is caused by low family income, poor living and lack of local medical treatment condition.

GI tract treatment and monitoring devices configured for temporary implantation in the GI tract and non-invasive removal via natural body processes are disclosed. Methods of implantation, treatment and monitoring with disclosed devices are also disclosed. Devices include bio-active fixation that allows removal from the body by natural processes after a time that may be engineered in the fixation elements. In some embodiments, devices are configured to be implanted on GI tract tissue and transmurally migrate into the GI tract to be passed from the body. In other embodiments, devices are configured for placement within the GI tract via a delivery tube such as an NJ / NG tube. Embodiments include stimulation devices for treating conditions such as ileus and sensors for monitoring GI leaks and / or biological or chemical markers for various GI tract conditions.

The invention discloses a traditional Chinese medicine for treatment of intestinal obstruction. The traditional Chinese medicine comprises: semen Raphani, immature bitter orange, rhubarb, radix paeoniae rubra and mirabilite. The traditional Chinese medicine for treatment of intestinal obstruction provided by the invention has the characteristics of rigorous Chinese medicinal prescription, scientific compatibility, obvious curative effect, no toxic or side effect, maximization of drug efficacy, convenient use, good patient compliance, low treatment cost, and no cause of economic burden to patients after long-term use, and is an ideal drug for treatment of mechanical intestinal obstruction.

The invention provides a medicine composition for treating ileus of equus animals. The medicine composition comprises the following raw medicines: Szechwan chinaberry fruit, cape jasmine fruit, cogon grass rhizome, Indian bread, gordon euryale seed, Chinese yam and pomegranate rinds. The medicine composition has the beneficial effects that the medicine composition takes activating collaterals and relaxing bowels and diminishing inflammation and expelling toxins as the treatment principles, has reasonable components, has simple preparation processes and has a wide range of application; the medicine composition is prepared from pure Chinese herbal medicines, has a wide source, is low in cost, has a high cure rate and does not have medicine residues or toxic or side effect; in particular, plant cell walls are furthest destroyed after superfine grinding, thus overcoming the defects that traditional medicine powder has high content of crude fibers and active ingredients are hard to dissolve out and being easier to absorb by horses; the medicine composition has obvious functions of activating collaterals and relaxing bowels and adjusting body functions, effectively treats ileus of equus animals and can shorten the recovery phase and avoid relapse compared with western medicines.

The invention relates to a traditional Chinese medicine for treating simple roundworm ileus, and especially relates to a traditional Chinese medicine composition prepared by taking plant Chinese herbal medicines as raw materials, for treating simple roundworm ileus. The traditional Chinese medicine is characterized by comprising bulk drugs preparing into effective components as follows: by weight, 10-30 g of dry ginger, 90-110 g of honey, 20-40 g of dark plum, 20-40 g of rheum officinale, 3-8 g of pericarpium zanthoxyli, and 5-15 g of betel nut. The components of the composition are compatible and complement each other; the traditional Chinese medicine has the efficacies of relieving exterior syndrome, dispersing cold, warming middle energizer to arrest vomiting, dissolving phlegm, introducing water, relieving heat, strengthening the middle warmer, moisturizing pathogenic dryness to loosen the bowel, detoxifying, relieving pain and the like; and the traditional Chinese medicine is synergistic in drug effects and none in side effects, and is capable of simultaneously treating principal and subordinate symptoms, and effectively curing simple roundworm ileus.

The invention discloses a traditional Chinese medicine for treating senile intestinal obstruction. The selected raw material medicine and its weight components are: 25 parts of Sophora flavescens, 25 parts of Atractylodes atractylodes, 30 parts of Smilax smilax, 20 parts of Plantago, 15 parts of capillary, 10 parts of agarwood, 10 parts of chuanxiong, 15 parts of rhubarb, 15 parts of petunias, and 50 parts of honey; its preparations include pills, powders, tablets, oral liquid preparations, and capsule preparations made by traditional preparation technology or modern preparation technology. It is found through clinical application that the present invention has the advantages of rapid action, obvious therapeutic effect, good tolerance, low cost and no toxic or side effects.

Provided herein is a bulk composition comprising the trihydrate form of (3S, 4R, 3′R)-6-[4-(4-amino-5-chloro-2-methoxy-benzoylamino)-3-methoxy-piperidin-1-yl]-hexanoic acid 1-azabicyclo[2.2.2]oct-3′-yl ester di-hydrochloride salt. Provided are also pharmaceutical compositions and dosage forms comprising the trihydrate form, and methods and uses for treating a gastrointestinal disorder in a subject with the trihydrate form. In some embodiments, the gastrointestinal disorder is gastroesophageal reflux disease (GERD), dyspepsia (such as functional dyspepsia or functional motility disorder), gastroparesis, paralytic ileus, post-operative ileus, emesis, nausea, heartburn, intestinal pseudo-obstruction, irritable bowel syndrome (IBS), constipation, enteral feeding intolerance (EFI), or esophagitis. In some embodiments, the gastrointestinal disorder is post-operative ileus, chronic grass sickness, constipation, megacolon, gastritis, gastrointestinal stasis, or abomasal emptying defect.

The invention relates to a health food and a preparation method thereof, and specifically relates to a healthcare and health preserving capsule and a preparation method thereof. The healthcare and health preserving capsule is used for nourishing women, beautifying, building the body and delaying ageing. The capsule is prepared by extracting and concentrating tremella fuciformis, Chinese yam, pearl barley, pawpaw, lotus seeds, cherry tomatoes, grape seeds, aloes, vitamin E, dried rose and lycium barbarum. The capsule is simple in preparation method and convenient to prepare; natural components above are scientifically extracted and then reasonably composited to prepare the healthcare product which is easily digested and absorbed; the capsule prepared by the method has the effects of invigorating spleen and supplementing Qi, nourishing liver and kidney, nourishing blood and liver, invigorating Qi and blood, improving sleeping, removing chloasma, improving skin moisture, achieving low heat, beautifying, relaxing bowels and expelling toxin, timely supplementing lost nemaline and protein caused by moderating in eating, quickly recovering physical strength, and keeping nice body form and nice skin for women, and has outstanding effects on treating constipation, ileus and endocrine dyscrasia.

A method of treating ileus in a subject by administering to the subject an effective amount of a pharmacological agent that increases the activity of cholinergic receptor in a subject. Examples of pharmacological agents are brain muscarinic agonist, cholinergic agonist or cholinesterase inhibitor. The methods of the present invention can be used to treat ileus caused by abdominal surgery, or administration of narcotics or chemotherapeutic agents such as during cancer chemotherapy.

The invention discloses an intestinal calculus and ileus treatment device by utilizing holmium lasers to crush stones. The device comprises a device box body, in which an air pressure device is arranged. The air pressure device comprises an air pressure pump. One side of the air pressure pump is provided with an air pressure output device. The air pressure output device comprises an air pressure bottle, in which a movable rod is arranged. A telescopic spring is arranged on the movable rod in a sleeving manner. One end of the movable rod is provided with a pressure board, below which an air pressure output bin is arranged. One side of the air pressure output bin is provided with an input opening. The other side of the air pressure output bin is provided with an output opening. An electronic element bin is arranged above the air pressure device. An information memorizer is arranged in the electronic element bin. One side of the information memorizer is provided with an ultrasonic wave source. The intestinal calculus and ileus treatment device by utilizing holmium lasers to crush stones has the following beneficial effects: treatment cost is reduced; data of lesions of patients is recorded, which is conducive to comparison of states of patients; and the device is easy to promote and apply.

The present invention discloses a thermotherapeutic medicated bag for restoring gastrointestinal function after abdominal operation and its production method. It is characterized by that its composition comprises 17 Chinese medicinal materials of radish seed, unripe tangerine peel, fennel fruit, unripe bitter orange, magnolia bark and others. Said invented bag can improve local blood circulation, promote restoration of gastrointestinal function afte abdominal operation, and also can obtain obvious therapeutic effect for curing incomplete intestinal adhesion, ileus, constipation and other abdominal chronic inflammation, etc.

Described herein are methods for use in the treatment of upper gastrointestinal disorders and conditions (e.g., dyspepsia, gastroparesis, postoperative gastrointestinal obstruction, functional esophageal disorders, functional gastroduodenal disorders, gastroesophageal reflux disease (GERD) or duodenal or gastric ulcer), as well as the peptides, compositions and related methods of other conditions and disorders described herein.

Disclosed herein are pharmaceutical compositions useful for the treatment and prevention of adhesions and ileus.

The present invention relates to a method of treating ileus in a patient comprising administering to the patient a pharmaceutical composition comprising carbon monoxide.