The invention discloses a traditional Chinese medicine composition for preventing and treating sheep stomatitis and a preparation method thereof. The traditional Chinese medicine composition comprises the following raw herbal materials: honeysuckle, forsythia, andrographis, folium isatidis, natural indigo, dandelion, Chinese violet, wild chrysanthemum, rhizoma smilacis glabrae, houttuynia, cohosh, mongolian snakegourd root, lithospermum purpurocaeruleum, lophatherum gracile, cortex phellodendri, cortex dictamni, meadowrue root and rhizome, circium japonicum, common cephalanoplos herb, garden burnet root, ramie root, bezoar, pearl, ferrosic oxide, borneol, potentilla freyniana, manystem stonecrop leaf, yarrow, assam crotalaria root, entada phaseoloides and hibiscus root. The traditional Chinese medicine composition for treating sheep stomatitis provided by the invention has the beneficial effects of mainly clearing away heat and toxic materials, and eliminating sore and reliving pain to diminish inflammation, sterilize and prevent virus, heal sores, prevent infection, and control state of an illness, supplementarily tranquilizing mind by nourishing the heart and treating yin deficiency by reinforcing body fluid to enhance immunity of sheep, and uneasily producing drug resistance due to low drug residues; the Chinese herbal medicines are selected, the cost price is low, and the administration is convenient.