The invention discloses a Baibei anti-tuberculosis pill for treating pulmonary tuberculosis, tuberculous pleuritis, peritonitis, empyema and bronchopleural fistula. The Baibei anti-tuberculosis pill is prepared by smashing decoction pieces of twenty one traditional Chinese medicines comprising pseudo ginseng, lily, fritillaria cirrhosa, radix ophiopogonis, honeysuckle flower, balloonflower root, radix scrophulariae, common hogfenneI root, rhizoma picrorhizae, selfheal, and the like, sieving, fully mixing to obtain a pill made with water, and drying at a low temperature. The Baibei anti-tuberculosis pill is a pure traditional Chinese medicine preparation, and has characteristics of wide medicine sources, easily available raw materials, simple process, convenient medicine taking, definite curative effects, and no damage, side effects or toxic effects to live and kidney. Through clinical observation, after taking of the pill, the body weight is obviously increased, the immunity is boosted, focuses, pleural effusion and fester are self-absorbed, encapsulated effusion is absorbed or shrank, and symptoms are eliminated completely. Compared with the prior art, the pill has advantages of short curative course, rapid production of desired effects, no relapse, obvious curative effects for drug-resistant, allergic and refractory pulmonary tuberculosis, tuberculous pleuritis, peritonitis, empyema and bronchopleural fistula, and value for wide popularization.