97 results about "Pleurisy" patented technology

The invention discloses a Chinese medicinal herb composition for treating pleurisy. The composition is characterized by being prepared from the following raw materials in part by weight: 15 to 25 parts of pepperweed seed, 35 to 45 parts of Chinese date, 15 to 25 parts of tuckahoe, 5 to 15 parts of cassia twig, 25 to 35 parts of largehead atractylodes rhizome, 5 to 15 parts of pericarpium trichosanthis, 5 to 15 parts of allium macrostemon bunge, 5 to 15 parts of ginger-processed pinellia rhizome, 5 to 15 parts of orange peel, 15 to 25 parts of sessile stemona root, 15 to 25 parts of root of red rooted salvia, 25 to 35 parts of baical skullcap root, 5 to 15 parts of humulus scandens merr, 5 to 15 parts of lanceolate codonopsis root and 5 to 15 parts of liquorice. The composition is prepared by the following steps of: adding 1,500 parts of water, boiling the raw materials for 3 times; filtering, recovering and extracting decoction; and bottling, and sterilizing at a high temperature for later use. The pepperweed seed is taken as a monarch medicament; the Chinese date and tuckahoe are taken as ministerial medicaments; the cassia twig, largehead atractylodes rhizome, pericarpium trichosanthis and allium macrostemon bunge are taken as adjuvant medicaments; the ginger-processed pinellia rhizome, orange peel, humulus scandens merr, sessile stemona root, root of red rooted salvia, baical skullcap root, lanceolate codonopsis root and liquorice are taken as conductant medicaments. The Chinese medicinal herb composition has the advantages of convenient and safe preparation and use, and obvious effect on treating the pleurisy.

The invention relates to a traditional Chinese medicine composition for treating pleurisy and a preparation method thereof. The traditional Chinese medicine composition is prepared from the following bulk drugs by weight: common selfheal fruit-spike, heartleaf houttuynia herb, trichosanthes root, root of large-flowered skullcap, oriental waterplantain rhizome, tansymustard seed, dandelion, Poria cocos, radish seed, red sage root, weeping forsythia capsule, polyporus, lily, glossy privet fruit, dendrobium, Chinese wolfberry root-bark, bitter apricot seed, peach seed, milkvetch root, starwort root, cassia twig, licorice, Chinese thorowax root, coptis, Chinese magnoliavine, corydalis tuber, mulberry bark, prepared pinellia tuber, banksia rose, ephedra stem, green tangerine peel, bitter orange, balloonflower root, rosewood and manchurian wildginger. The invention has the following advantages: the traditional Chinese medicine composition a substantial curative effect, fast action and no toxic and side effects; the preparation method is simple; etc.

The invention discloses a new medical use of myricetin, belonging to the technology field of medicines. Through acetic acid writhing test, formaldehyde-induced pain test, glacial acetic acid-induced capillary permeability test, dimethybenzene-induced mouse ear swelling test, egg white and carrageenin-induced paw edema test, test of leukocytoplania of pleurisy caused by carboxymethyl cellulose, granuloma (chronic) inflammation test, and screening of adjuvant arthritis animal models with primary and secondary inflammations, the myricetin is found to have high antiphlogistic and analgesic activity and can prevent and treat adjuvant arthritis, the antiphlogistic activity of myricetin is equivalent to that of aspirin but no gastrointestinal toxicity, and the anti-rheumatoid arthritis activity of myricetin is equivalent to that of Tripterygium wilfordii, and the myricetin has liver protecting effect and is an ideal drug for preventing and treating acute and chronic inflammations and rheumatoid arthritis. The myricetin can be prepared into various preparations with pharmaceutically-acceptable carrier for relieving inflammations, reliving pain and treating rheumatoid arthritis.

The invention relates to a Chinese medicine composition for treating tuberculous pleurisy. The composition is prepared from the following Chinese medicines, by weight: 3 to 25 parts of ardisia japonica herbs, 3 to 20 parts of veronicastrum herbs, 3 to 20 parts of sweetgum fruits, 3 to 20 parts of selfheal spikes, 3 to 20 parts of houttuynia herbs, 3 to 20 parts of bletilla rhizomes, and 3 to 9 parts of licorice roots. The composition is a substitute for hormone medicines to reduce swelling and cure tuberculous pleural effusion. The composition has effects of dispelling wind, eliminating dampness, soothing the liver, invigorating the collaterals, and promoting dieresis, has some inhibition effect on mycobacterium tuberculosis, has an astringent effect on a tuberculous focus, can reduce fluid exudation at the tuberculous focus, and promotes circulation in lymphatic vessels, so that interstitial fluid is rapidly removed and absorbed. If the composition is orally taken and combined with anti-tuberculosis drugs to treat the tuberculous pleurisy, the effective rate and the cure rate are 100% and 98.7% respectively; it takes no more than 30 days to remove effusion; a whole treatment takes no more than 12 months; no significant toxic and side effects are observed; and there is no damage to liver, kidney, and stomach functions.

The invention discloses a traditional Chinese medicine composition for treating pleuritis, which is prepared from the following components in parts by weight: 5-7g of ephedra, 5-7g of cassia twig, 9-11g of radix bupleuri, 10-14g of Baikal skullcap root, 2-4g of licorice root, 8-12g of almond, 28-32g of plaster stone, 8-12g of rhizoma anemarrhenae, 28-32g of coix seed, 8-12g of haricot, 28-32g of radix psuedostellariae and 28-32g of herba houttuyniae. The traditional Chinese medicine composition for treating pleuritis has the effects of dissipating the wind-cold externally, eliminating shaoyang internally, clearing yangming and eliminating dampness, and has the advantages of favorable treatment effect on pleuritis, quick effect taking and no toxic or side effect.

The invention discloses a Baibei anti-tuberculosis pill for treating pulmonary tuberculosis, tuberculous pleuritis, peritonitis, empyema and bronchopleural fistula. The Baibei anti-tuberculosis pill is prepared by smashing decoction pieces of twenty one traditional Chinese medicines comprising pseudo ginseng, lily, fritillaria cirrhosa, radix ophiopogonis, honeysuckle flower, balloonflower root, radix scrophulariae, common hogfenneI root, rhizoma picrorhizae, selfheal, and the like, sieving, fully mixing to obtain a pill made with water, and drying at a low temperature. The Baibei anti-tuberculosis pill is a pure traditional Chinese medicine preparation, and has characteristics of wide medicine sources, easily available raw materials, simple process, convenient medicine taking, definite curative effects, and no damage, side effects or toxic effects to live and kidney. Through clinical observation, after taking of the pill, the body weight is obviously increased, the immunity is boosted, focuses, pleural effusion and fester are self-absorbed, encapsulated effusion is absorbed or shrank, and symptoms are eliminated completely. Compared with the prior art, the pill has advantages of short curative course, rapid production of desired effects, no relapse, obvious curative effects for drug-resistant, allergic and refractory pulmonary tuberculosis, tuberculous pleuritis, peritonitis, empyema and bronchopleural fistula, and value for wide popularization.

The invention discloses an automatic identifying and positioning system of pleura lines through ultrasonic, based on Radon transformation. The automatic identifying and positioning system is characterized by consisting of an ultrasonic image cropping module, a Radon transformation module, an image rotation module, a pleura line extracting module and a pleura line identifying and positioning module. Through a Radon transformation technique, peak points of pleura lines are extracted from cropped ultrasonic images, the range section of a pleura line transverse projection is obtained, and pleura lines are extracted, so that identifying and positioning of the pleura lines are realized. Compared with the prior art, the automatic identifying and positioning system disclosed by the invention has the advantages that the pleura lines can be quickly and accurately identified through combination of dissecting and dynamic characteristics of pleura, detection of the pleura lines can be more objective, quantitative evaluation of the pleura can be realized, diagnosis of some pleura diseases such as pleura inflammation and ultrasonic guided pleura puncture are facilitated, the confidence of inexperienced doctors for daily clinical diagnosis is increased, the efficiency of clinical operations is improved, and the automatic identifying and positioning system has great application prospects.

The invention relates to a traditional Chinese medicine composition for preventing and treating infectious pleurisy of pigs. The traditional Chinese medicine composition is prepared by scutellaria baicalensis, common andrographis herb, white mulberry root barks, Chinese wolfberry root barks, licorice, ginkgo, ephedra, perillaseed, pinellia ternate, almonds and Chinese magnoliavine fruits and can be powder. A preparation method comprises the steps of 1 smashing traditional Chinese medicine to be at 40-60 meshes, weighing the traditional Chinese medicine according to a formula and performing three-dimentional mixing to obtain traditional Chinese medicine powder; 2 throwing the mixed traditional Chinese medicine powder and 2-3 times of amount of water into an extraction tank to stay overnight for dipping; 3 heating hydrolysate to be at the temperature ranging from 40 DEG C to 100 DEG C and performing extraction for 8-12 hours; 4 filtering and removing medicine residues and standing filtrate for standby; 5 re-throwing the medicine residues into the extraction tank, adding water to repeat the step 3; 6 filtering and removing the medicine residues, mixing obtained liquid with the liquid extracted for the first time, and performing direct filling to obtain finished product, wherein the packing specification is 100-200 ml / per bag. The traditional Chinese medicine composition can effectively prevent and treat the infectious pleurisy of the pigs and has the effects of removing heat from the lung to relieve cough, resolving sputum and relieving asthma, and the recovery rate is higher than 90%.

The invention discloses a medicine capable of treating tuberculosis and osteomyelitis. A preparation method of the medicine comprises the steps of grinding baked dinodon rufozonatum, baked centipede, astragalus membranaceus, angelica sinensis, scutellaria baicalensis, dangshen, bighead atractylodes rhizome, angelica dahurica, radix stemonae, honeysuckle, radix rehmanniae, liquorice, radix cyathulae and poria cocos into fine powder, mixing, and refining into pills by using honey. The medicine has an obvious treatment effect on pulmonary tuberculosis, pleurisy, osteoarticular tuberculosis, tuberculosis of cervical lymph nodes, osteomyelitis and the like. After the tuberculosis of cervical lymph nodes ruptures, a thread covered with dinodon rufozonatum powder is inserted into the tuberculosis of cervical lymph nodes, and the medicine has internal and external treatment effects; after sinus tracts form in an osteomyelitis patient, the thread covered with the dinodon rufozonatum powder is inserted into the tracts, fester can be quickly discharged, sequestrum automatically comes off, and osteotrauma automatically repairs to recovery. The medicine does not increase the surgery pain of patients, has no side effects and does not cause serious allergy or damage internal organs after long-term taking; the medicine only needs to be taken at home, and holed cauterized needling can be applied in small clinics, so that the medicine expenses are small. The curative ratio of the tuberculosis diseases is above 99%, and the curative ratio of the osteomyelitis is above 90%.

The invention discloses a traditional Chinese medicine for treating internal heat type pleurisy due to yin deficiency, and weight ratio of each raw material is as follows: licorice 2-4, almond 6-10, houttuynia 1-3, hop 1-3, anemarrhena 10-14, myotonin 13-17, rhizome of bornet cowlily 6-8, gypsum 13-17, pseudostellaria root 28-32, white birdnest cup 10-14, ephedra stem 6-10, cassia twig 5-7, radix bupleuri 8-11, scutellaria 10-14 and Eria corneri 2-6. The traditional Chinese medicine composition comprises traditional Chinese medicine for nourishing yin and clearing heat, and has a good curative effect for treating internal heat type pleurisy due to yin deficiency without toxic and side effect.

The invention discloses a traditional Chinese medicine composition for treating pleurisy and preparation method thereof, and the product is composed the following ingredients by weight: 14-16 parts of stellaria root, 14-16 parts of scutellaria; 14-16 parts of oyster powder; 6-8 parts of licorice; 9-11 parts of almond; 5-7 parts of trichosanthes bark; 3-5 parts of santal; 7-9 parts of ginger; 9-11 parts of peking euphorbia; 9-11 parts of Gansui root; 4-6 parts of wild ginger flower; 2-4 parts of hollyhock flower; 8-12 parts of gypsum; 4-6 parts of anemarrhena; 3-5 parts of perilla; 2-4 parts of rose of Sharon; 5-7 parts of ephedra stem; 5-7 parts of cape jasmine; 8-10 parts of glittering pricklyash; 2-5 parts of roughhaired holly root; 5-7 parts of cassia twig; 10-15 parts of red ginseng and 4-6 parts of cordate houttuynia; The traditional Chinese medicine composition of the present invention can treat pleurisy, and has the efficacies for dissipating the cold, harmonizing the lesser yang, clearing the yang, transforming dampness, and has the advantages of good curative effect, fast effectiveness without any toxic and side effects.

The invention discloses prunella vulgaris traditional Chinese medicine oral liquid for adjuvant therapy of pleurisy. The prunella vulgaris traditional Chinese medicine oral liquid is made of the following active pharmaceutical ingredients, by weight: 100-200 parts of asparagus cochinchinensis, 150-300 parts of prunella vulgaris, 100-200 parts of plantain seed, 100-200 parts of cortex lycii radicis, 100-200 parts of Chinese honeylocust spine and 30-60 parts of honey-fried licorice root. The traditional Chinese medicine oral liquid has the effects of nourishing yin and benefiting qi, nourishingblood and moistening dryness, clearing heat and removing toxicity, moistening lung and eliminating phlegm, carrying out detumescence and apocenosis and removing wind and toxin, the special medicine is used for special cure, and the therapeutic effect is remarkable.

The invention relates to an anti-tuberculosis Chinese medicine, a special adjuvant medicine and a preparation method thereof. Pharmaceutically-effective raw materials of the anti-tuberculosis Chinese medicine comprise blister beetle, drgon's bone, oyster, chicken gizzard-membrane, pumice and egg white of 10 eggs (yolk removed). The adjuvant medicine is water soaking liquid or water decoction of one or more selected from milkvetch root, licorice root, ginseng, radix codonopsis, milkvetch root, red jujube and wine-processed twotoothed achyranthes root. The medicine has the effects of removing blood stagnation and eliminating pathogenic accumulation, and is mainly used to treat pulmonary tuberculosis, tuberculous pleurisy, pyogenic osteomyelitis, bone tuberculosis, tuberculosis of thoracic and lumbar vertebra, lymphoid tuberculosis, tuberculous peritonitis, silicosis complicated with tuberculosis, and acute lymphadenitis.

The invention discloses a Chinese herbal medicine for treating pulmonary diseases. Each dose of the Chinese herbal medicine contains the following raw medicines in proportions by weight: 6-12g of cassytha filiformis, 6-15g of mulberry leaf, 10-20g of houttuynia, 6-12g of impatiens chinensis, 6-12g of ficus simplicissima lour and 3-10g of berchemia lineata. According to the ancestral prescription, the inventor makes an improvement on the basis of ''a medicine for treating pulmonary diseases-Feijiling'' invented by the inventor previously, i.e. the cassytha filiformis and the mulberry leaf are added. The Chinese herbal medicine disclosed by the invention can be used for effectively curing pneumonia, pulmonary abscess and pulmonary tuberculosis, has an effect on treating pleuritis or pleural effusion and drug-tolerant pulmonary tuberculosis complicated with pulmonary diseases, has the advantages of short course of treatment, wide raw medicine sources, low cost and no obvious toxic side effects, and can effectively relieve the burden and pain of patients.

The invention provides a Chinese herbal medicine composition for treating pleurisy. The Chinese herbal medicine composition consists of the following components in parts by weight: 20-25 parts of pepperweed seed, 40-45 parts of Chinese date, 20-25 parts of indian buead, 10-15 parts of cassia twig, 30-35 parts of large-head atractylodes rhizome, 10-15 parts of snakegourd peel, 10-15 parts of longstamen onion bulb, 10-15 parts of pinellia, 10-15 parts of orange peel, 20-25 parts of sessile stemona root, 20-25 parts of red-rooted salvia root, 30-35 parts of baikal skullcap root, 10-15 parts of scandent hop, 10-15 parts of lance asiabell root and 10-15 parts of liquoric root. The Chinese herbal medicine composition is prepared by carrying out the following steps: adding 1600 parts of water, boiling in an earthen pot, decocting with soft fire for 20-30 minutes, collecting supernatant, and repeating for three times; mixing supernatant decocted in three times, bottling, and sterilizing at high temperature for later use. In the composition, the pepperweed seed is taken as a monarch; the Chinese date and the indian buead are taken as ministers; the cassia twig, the large-head atractylodes rhizome, the snakegourd peel and the longstamen onion bulb are taken as assistants; the pinellia, the orange peel, the scandent hop, the sessile stemona root, the red-rooted salvia root, the baikal skullcap root, the lance asiabell root and the liquoric root are taken as guides.

A carboxylic acid compound represented by formula (I): (meanings of the symbols in the formula are as mentioned in the specification) and a pharmaceutical agent comprising the compound. <>Since the compound represented by formula (I) binds to a DP receptor and shows antagonistic activity for the DP receptor, it is useful for prevention and / or treatment of diseases such as allergic disease (such as allergic rhinitis, allergic conjunctivitis, atopic dermatitis, bronchial asthma and food allergy), systemic mastocytosis, disorders accompanied by systemic mast cell activation, anaphylaxis shock, bronchoconstriction, urticaria, eczema, diseases accompanied by itch (such as atopic dermatitis and urticaria), diseases (such as cataract, retinal detachment, inflammation, infection and sleeping disorders) which is generated secondarily as a result of behavior accompanied by itch (such as scratching and beating), inflammation, chronic obstructive pulmonary diseases, ischemic reperfusion injury, cerebrovascular accident, chronic rheumatoid arthritis, pleurisy, ulcerative colitis and the like. Carboxylic acid compounds represented by the following general formula (I) (wherein each symbol is as defined in the description) and drugs containing these compounds: (I) Because of binding to DP receptor and antagonizing the same, the compounds represented by the general formula (I) are useful in preventing and / or treating allergic diseases (allergic nephritis, allergic conjunctivitis, atopic dermatitis, bronchial asthma, food allergy, etc.), systemic mast cell disease, systemic mast cell activation failure, anaphylactic shock, respiratory tract contraction, urticaria, eczema, diseases associated with itch (atopic dermatitis, urticaria, etc.), diseases (cataract, retinal detachment, inflammation, infection, sleep disorder, etc.) secondarily caused by behaviors associating itch (scratching, beating.

The invention discloses a traditional Chinese medicine composition for treating pleurisy and a preparation method thereof. The traditional Chinese medicine preparation for treating pleurisy comprises, by weight, 5-10 parts of sweet potato leaf, 3-8 parts of Pyrrosia lingua leaf, 3-5 parts of cortex lycii radices, 10-15 parts of American ginseng, 1-3 parts of cordyceps sinensis, 5-10 parts of herba cistanches, 3-8 parts of herba hyperici japonica, 10-15 parts of reed rhizome, 8-12 parts of gastrodia tuber, 8-12 parts of radix peucedani, 3-8 parts of whiteflower patrinia herb, 5-10 parts of licorice root, 5-10 parts of cortex phellodendri, 3-8 parts of coix seed, 4-6 parts of root of Chinese thorowax, 10-20 parts of lotus seed, 3-8 parts of Houttuynia cordata, 5-10 parts of cacumen biotae, 3-8 parts of uncaria rhynchophylla, 8-12 parts of cassia bark and 3-5 parts of castor bean. The traditional Chinese medicine composition for treating pleurisy has the effects of dispersing wind cold, harmonizing Shaoyang, smoothing yangming meridians, and resolving dampness, and has the advantages of fastness to take effect, effectiveness and no toxic and side effects in treating pleurisy.

The invention discloses a Miao (Miao is one of ethnic minorities in China) drug for treating a lung disease and relates to the Miao drug taking Chinese herbal medicines as raw materials. The Miao drug comprises the following raw materials by mass: 6-12 g of brooklet anemine root, 6-12 g of common tripterospermum herb, 6-12 g of dandelion, 6-12 g of platycodon grandiflorum and 6-12 g of cordate houttuynia. The lung disease is pleuritis, or pleural tuberculosis, or pulmonitis, or infiltrative pulmonary tuberculosis, or fibrous pulmonary tuberculosis, or hematogenous pulmonary tuberculosis, or perforated pulmonary tuberculosis. A preparation method for the Miao drug comprises the following steps: preparing the raw materials according to a formula; decocting by using clear water; concentrating; and filtering to remove the leaves so as to obtain a decoction; or mixing the raw materials, grinding into powder, taking water as an adhesive agent, widely preparing into pills, and drying to prepare the pills; or uniformly mixing the raw materials, grinding, and encapsulating to prepare a capsule. The Miao drug has the characteristics of quick action, high healing rate, no side effect, no relapse after healing, wide material source and easiness in processing, and is suitable for treating patients with the pleuritis, the pleural tuberculosis, the pulmonitis or phthisis.

The invention relates to the field of traditional Chinese medicine preparations, in particular to a traditional Chinese medicine preparation for treating pleurisy caused by yin deficiency. The preparation is prepared from, by weight, 15-20 parts of tofieldia divergens bur. et Franch., 5-10 parts of scrophularia kakudensis fianch, 15-20 parts of blackend swallowwort roots, 15-20 parts of bupleurum falcatum, 15-20 parts of salvia substolonifera, 15-20 parts of sea buckthorns, 10-15 parts of caryopteris terniflora maxim., 10-15 parts of lutetiana sp. Quadrisulcata, 5-10 parts of ginseng, 10-15 parts of dragon bones, 10-15 parts of radix astragali and 5-10 parts of monkshood. The traditional Chinese medicine preparation for treating pleurisy is prepared according to the traditional Chinese medicine theory, various traditional Chinese medicines are combined and achieve the maximum medicine effect for pleurisy treatment, toxic and side effects are small, the cost is low, and both symptoms and root causes are treated.

The invention relates to a hydrothorax exosome metabolite combination, a kit and a method for diagnosing tuberculous pleurisy. The hydrothorax exosome metabolite combination for diagnosing the tuberculous pleurisy is prepared from dimethylglycine, choline, acyl carnitine with the ratio of 10: 2, phosphatidylcholine with the ratio of 35: 6, phosphatidylcholine o with the ratio of -36: 0, phosphatidylethanolamine with the ratio of 33: 2, sphingomyelin with the ratio of 28: 1 and oleic acid. The kit for diagnosing the tuberculous pleurisy comprises an internal standard substance required for detecting the concentration of the metabolites in the hydrothorax exosome sample extraction solution. A combined marker provided by the invention has the characteristics of high sensitivity and high specificity for the diagnosis of tuberculous pleurisy, and meanwhile, can be complementary with the traditional marker adenosine deaminase, and can be used for the auxiliary diagnosis of the tuberculous pleurisy by being combined with the traditional marker adenosine deaminase.

The invention relates to the technical field of traditional Chinese veterinary medicine, in particular to a traditional Chinese medicine composition for preventing and treating common autumn diseases of sheep, a preparation method and application thereof. The traditional Chinese medicine composition comprises isatis root, tinglizi, loquat leaf and licorice. The invention belongs to pure traditional Chinese medicine formula, has the advantages of safety and effectiveness, reduced cost, easy material acquisition, simple and convenient processing, no toxic and side effects, etc., and is suitable for sheep prone to influenza, bronchitis, pneumonia, gastroenteritis, forestomach obstruction, stomatitis, and sheep in autumn. Oral sores, viral encephalitis, infectious conjunctivitis, pleurisy, indigestion, and other diseases, etc., all have significant preventive effects. At the same time, the use of the traditional Chinese medicine composition of the present invention can reduce or even avoid the residue and harm of chemical drugs, and promote the development of sheep diseases. The development of healthy farming provides people with healthy and harmless products, which has significant social significance.

The invention relates to a hydrothorax microparticle metabolite combination, a kit and a method for diagnosing tuberculous pleurisy. The pleural effusion microparticle metabolite composition for diagnosing tuberculous pleurisy comprises phenylalanine, tyrosine, methionine, kynurenine, lauroyl carnitine, glycine-binding chenodeoxycholic acid, phosphatidylcholine with the ratio of 36: 7 and lysophosphatidylcholine with the ratio of 20: 2. The kit for diagnosing tuberculous pleurisy comprises an internal standard substance for detecting the concentration of metabolites in the pleural effusion microparticle sample extraction solution. A combined marker provided by the invention has the characteristics of high sensitivity and high specificity for the diagnosis of tuberculous pleurisy, at the same time, can be complementary with a traditional marker adenosine deaminase, and can be used for the auxiliary diagnosis of the tuberculous pleurisy by being combined with the traditional marker adenosine deaminase.

The invention discloses a real-time fluorescent quantitative PCR (polymerase chain reaction) kit for assisting diagnosis of tuberculous pleuritis and application thereof. The kit comprises a primer and a probe which are used for detecting mycobacterium tuberculosis specific small RNA fragments (Mtb-ms-1 and Mtb-ms-2), and a sequence of Mtb-ms-1 is shown as SEQ ID NO.1, and a sequence of Mtb-ms-2 is shown as SEQ ID NO.2. Total RNA of little pleural fluid of a patient with pleuritis is extracted, mycobacterium tuberculosis specific small RNA segments in the total RNA are reversely transcribed into complementary cDNA, and a specific primer probe is applied for real-time fluorescent quantitative polymerase chain reaction detection, so that the kit is high in diagnosis sensitivity and specificity, can remarkably differentiate tuberculous pleuritis and a comparison group and is better than diagnosis methods like mycobacterium tuberculosis culture, anti-fast smear staining and DNA detection.

The invention relates to a production method of semen lepidii and fructus jujubae lung purging granules, in particular to production of semen lepidii and fructus jujubae lung purging granules from twobulk medicine materials of fructus jujubae and semen lepidii through technologies of pretreatment, decoction, decotion with stir-fried semen lepidii wrapped, filtering, concentration, drying, granulation and the like, and belongs to the field of traditional Chinese medicine preparations. The obtained semen lepidii and fructus jujubae lung purging granules have the efficacy of purging the lung, inducing diuresis, descending qi and dissolving phlegm, and are used for treating respiratory system disease of pulmonary heart disease, emphysema, wet pleurisy, lobar pneumonia, bronchial asthma, chronic bronchitis, pertussis and the like, the recipe is simple, however, the semen lepidii and fructus jujubae lung purging granules have significantly-curative and excellent effects. According to production of the semen lepidii and fructus jujubae lung purging granules from the two bulk medicine materials of the fructus jujubae and the semen lepidii through the technologies of pretreatment, decoction, decotion with the stir-fried semen lepidii wrapped, filtering, concentration, drying, granulation and the like, by conducting dosage form reform and innovation on traditional Chinese medicine decotion, the problems that production, taking and carrying are inconvenient, and the like can be effectively solved, the production method of the semen lepidii and fructus jujubae lung purging granules isscientific and reasonable, the materials for efficacy are kept furthest, and large-scale production is easy, so that the production method of the semen lepidii and fructus jujubae lung purging granules has significant economic benefits and application prospects.

The invention discloses a Chinese medicine for curing pleurisy. The Chinese medicine consists of following components, in parts by weight, 10 to 12 parts of cordate houttuynia, 10 to 12 parts of hypericum japonicum, 10 to 12 parts of cirsium japonicum, 3 to 5 parts of coptis, 1 to 2 parts of gen-seng, 10 to 12 parts of poria cocos, 6 to 9 parts of villous amomum fruit, 6 to 9 parts of bighead atractylodes rhizome, 6 to 9 parts of stellaria yunnanensis, 6 to 9 parts of cyperus rotundus, 3 to 5 parts of China rose, 10 to 12 parts of chinese waxgourd peel, 6 to 9 parts of radix bupleuri, 10 to 12 parts of hance brandisia herb, 10 to 12 parts of finelydivided phtheirospermum, and 10 to 12 parts of cortex moutan. The Chinese medicine is used for curing pleurisy, has the functions of clearing away heat and toxic materials, regulating the middle warmer, resolving dampness, invigorating spleen-stomach and replenishing qi, and has the advantages of good and quick pleurisy curative effect and no toxic or side effects.

The invention discloses a Chinese medicine for treating pleurisy due to combined phlegm and blood stasis. The Chinese medicine comprises raw materials of, by weight, 2-4 parts of humulus lupulus, 5-7 parts of ephedra stem, 5-7 parts of cassia twig, 8-12 parts of anemarrhena, 6-10 parts of cordate houttuynia, 6-8 parts of floating ferns, 9-11 parts of radix bupleuri, 8-12 parts of baikal skullcap roots, 1-3 parts of chloranthus japonicas sieb, 13-17 parts of coix seeds, 8-12 parts of hyacinth beans, 6-8 parts of herba salviae chinesnsis, 8-12 parts of almonds, 13-17 parts of gypsum and 8-14 parts of carex brownii tucker. The Chinese medicinal composition by the invention employs a Chinese medicine which activates blood, dissolves stasis, facilitates qi and activates collaterals, has good therapeutic effects on treating pleurisy patients due to combined phlegm and blood stasis, and has no toxic and side effects.

The invention discloses an anti-tuberculosis drug and a production method thereof. The anti-tuberculosis drug is mainly prepared from 3-15 parts of rhubarb, 9-15 parts of radix paeoniae alba, 6-15 parts of bletilla striata and 0.1-0.3 part of Semen Crotonis Pulveratum, and is made into pills. The Semen Crotonis Pulveratum is a mixture of croton seed powder and starch. The drug is completely made of Chinese herbal medicines, has the advantages of tuberculosis resistance and sterilization, pus expelling and tissue regeneration promotion, swelling and pain relieving, nerve repairing, promotion of tuberculosis focus absorption and repair, and strengthening of body immune function, etc., is mainly applicable to bone and joint tuberculosis complicated with abscess sinus, spinal tuberculosis complicated with pulmonary tuberculosis, lymphoid tuberculosis, tuberculous pleuritis, intestinal tuberculosis and renal tuberculosis, etc., also has no pain and risk of surgical trauma, and especially has the advantages of small toxic and side effect and adverse reaction, quick effect, short course of treatment and low price, etc.

The invention provides liquid medicine capable of eliminating pathogens from lung for expelling fluid retention and relieving cough and asthma. The medicine is prepared from 25-35 grams of radix codcnopsitis pilosulas, 20-25 grams of radix ophiopogonis, 15-25 grams of fructus schisandrae chinensis, 25-50 grams of radix astragali, 15-25 grams of fructus aurantii immaturus, 15-25 grams of cortex magnoliae officinalis, 15-20 grams of fructus psoraleae, 20-30 grams of radix salviae miltiorrhizae, 20-30 grams of radix paeoniae rubra, 15-20 grams of herba epimedii, 20-30 grams of semen descurainiae(wrap-boiling), 15-20 grams of radix polygonati officinalis, 10-15 grams of root of rhodiola rosea, 10-15 grams of ramulus cinnamomi, 5-10 grams of liquorice, 20-30 grams of rhizoma phragmitis, 20-30grams of coix seed, 15-20 grams of peach kernel, 15-20 grams of wax gourd seed, 12-18 grams of rhizoma polygoni cuspidate, 10-15 grams of fried radix stemonae, 6-12 grams of radix platycodonis, 25-35grams of fructus trichosanthis, 10-15 grams of rhizoma coptidis, 10-15 grams of radix scutellariae, 6-12 grams of rhizoma pinelliae, 5-10 grams of fried herba ephedra, 26-36 grams of herba houttuyniae, 3 grams of gecko (removing head and tail and boiling or administrating after dissolution) and 20 pieces of fructus ziziphi jujubae. The medicine has the effects of benefiting heart, clearing lung, tonifying kidney, relieving cough and asthma and expelling fluid retention, and treating pulmonary heart diseases, congestive heart failure, hydrothorax, ascites and pleurisy, and compared with westernmedicine, the medicine is taken easily, and has low cost and good effect.

The invention relates to a hydrothorax fluid metabolite combination, a kit and a method for diagnosing tuberculous pleurisy. The hydrothorax fluid metabolite combination for diagnosing tuberculous pleurisy comprises dimethylglycine, tyrosine, kynurenine, nicotinamide, betaine, acylcarnitine with the ratio of 12: 0, acylcarnitine with the ratio of 14: 2 and phosphatidylcholine with the ratio of 42:8. The kit for diagnosing tuberculous pleurisy comprises an internal standard substance required for detecting the concentrations of dimethylglycine, tyrosine, kynurenine, nicotinamide, betaine, acylcarnitine with the ratio of 12: 0, acylcarnitine with the ratio of 14: 2 and phosphatidylcholine with the ratio of 42: 8 in a pleural effusion sample extraction solution. A combined marker provided bythe invention has the characteristics of high sensitivity and high specificity for the diagnosis of tuberculous pleurisy, meanwhile, can be complementary with the traditional marker adenosine deaminase, and can be used for the auxiliary diagnosis of the tuberculous pleurisy by being combined with the traditional marker adenosine deaminase.