35 results about "Tuberculous pleurisy" patented technology

The invention discloses a Chinese medicinal pill preparation for treating tuberculosis pleuritis, peritonitis, empyema and broncho-pleural fistula, which is prepared from 26 kinds of Chinese medicinal herbs including notoginseng, lily bulb, Sichuan fritillary bulb, lepidium seed, selfheal and weeping forsythia through steps of disintegrating, sieving, mixing homogenously, making water pills, and drying at low temperature.

The invention relates to a traditional Chinese medicine composition for curing phthisis and tuberculous pleurisy. The composition provided by the invention is prepared from the following raw materials: 8-15g of American ginseng, 5-8g of ginseng, 20-30g of radix astragali, 5-8g of pearls, 5-7g of walnuts, 20-30g of herba epimedii, 5-7g of toad oil, 2-3g of Chinese caterpillar fungus, 15-25g of flax, 5-10g of hide glue, 20-30g of mulberry, 10-20g of lilium brownie, 5-15g of burdock and 2-3g of multifloral honey. The traditional Chinese medicine composition can rapidly enhance the functions of four immune systems, and has the efficacies of dispersing lung Qi and supplementing vitality, moistening the lung for arresting cough, regulating blood and qi circulation, enriching blood and qi, dispelling melancholy and soothing chest, reinforcing sufficiency of fiver organs, tonifying vitality of six spleens, restoring qi, and preventing and curing diseases. After the composition is taken, the clinical symptoms of phthisis can be rapidly alleviated, the composition becomes effective within 5-15 days, one month is a treatment course, phthisis patients can be cured after 2-3 treatment courses generally, and the treatment effect is preferable for phthisis drug resistant persons.

The invention relates to a Chinese medicine composition for treating tuberculous pleurisy. The composition is prepared from the following Chinese medicines, by weight: 3 to 25 parts of ardisia japonica herbs, 3 to 20 parts of veronicastrum herbs, 3 to 20 parts of sweetgum fruits, 3 to 20 parts of selfheal spikes, 3 to 20 parts of houttuynia herbs, 3 to 20 parts of bletilla rhizomes, and 3 to 9 parts of licorice roots. The composition is a substitute for hormone medicines to reduce swelling and cure tuberculous pleural effusion. The composition has effects of dispelling wind, eliminating dampness, soothing the liver, invigorating the collaterals, and promoting dieresis, has some inhibition effect on mycobacterium tuberculosis, has an astringent effect on a tuberculous focus, can reduce fluid exudation at the tuberculous focus, and promotes circulation in lymphatic vessels, so that interstitial fluid is rapidly removed and absorbed. If the composition is orally taken and combined with anti-tuberculosis drugs to treat the tuberculous pleurisy, the effective rate and the cure rate are 100% and 98.7% respectively; it takes no more than 30 days to remove effusion; a whole treatment takes no more than 12 months; no significant toxic and side effects are observed; and there is no damage to liver, kidney, and stomach functions.

The invention relates to a traditional Chinese medicine composition for treating pulmonary tuberculosis, which comprises the following components of lilium brownie, ladybell root, lilyturf root, rehmannia, ginseng, cortex lycii, bulbus fritillariae cirrhosae, radix stemonae,common bletilla pseudobulb, radix astragali, Chinese yam and radix ranunculi ternati. The traditional Chinese medicine composition has the effect of nourishing yin for moistening lung, replenishing qi and invigorating the spleen, and can be used for preparing a medicine for preventing and treating pulmonary tuberculosis and/or lymph gland tuberculosis and/or tuberculous pleurisy. The invention also relates to a preparation method of the traditional Chinese medicine composition, which adopts different extraction methods according to the medicine properties of different herbal medicines to extract effective components in the herbal medicines maximally, thus enhancing medicine effect.

The invention discloses a kit for detection or assisted detection of tuberculous pleurisy. The kit comprises a device for detecting the expression amount of an immune factor, wherein the immune factor comprises (1) IL-6, IL-13, G-CSF, CCL1, CCL21, IP-10 (CXCL10), CCL8 (MCP-2), CXCL9 (MIG) and CXCL12 (SDF-1); or (2) at least one of IL-6, IL-13, G-CSF, CCL1, CCL21, IP-10 (CXCL10), CCL8 (MCP-2), CXCL9 (MIG) and CXCL12 (SDF-1). Experiments prove that a method for specifically identifying tuberculous pleurisy by taking hydrothorax as a detection object, utilizing a group of immunologic molecular marker, and adopting a multiple-factor microsphere detection technique is developed, and the purposes of improving the disease diagnosis accuracy rate, scientifically judging the state of illness and the like are realized by a multiple-factor combination manner.

The invention relates to an anti-tuberculosis Chinese medicine, a special adjuvant medicine and a preparation method thereof. Pharmaceutically-effective raw materials of the anti-tuberculosis Chinese medicine comprise blister beetle, drgon's bone, oyster, chicken gizzard-membrane, pumice and egg white of 10 eggs (yolk removed). The adjuvant medicine is water soaking liquid or water decoction of one or more selected from milkvetch root, licorice root, ginseng, radix codonopsis, milkvetch root, red jujube and wine-processed twotoothed achyranthes root. The medicine has the effects of removing blood stagnation and eliminating pathogenic accumulation, and is mainly used to treat pulmonary tuberculosis, tuberculous pleurisy, pyogenic osteomyelitis, bone tuberculosis, tuberculosis of thoracic and lumbar vertebra, lymphoid tuberculosis, tuberculous peritonitis, silicosis complicated with tuberculosis, and acute lymphadenitis.

The invention relates to a hydrothorax exosome metabolite combination, a kit and a method for diagnosing tuberculous pleurisy. The hydrothorax exosome metabolite combination for diagnosing the tuberculous pleurisy is prepared from dimethylglycine, choline, acyl carnitine with the ratio of 10: 2, phosphatidylcholine with the ratio of 35: 6, phosphatidylcholine o with the ratio of -36: 0, phosphatidylethanolamine with the ratio of 33: 2, sphingomyelin with the ratio of 28: 1 and oleic acid. The kit for diagnosing the tuberculous pleurisy comprises an internal standard substance required for detecting the concentration of the metabolites in the hydrothorax exosome sample extraction solution. A combined marker provided by the invention has the characteristics of high sensitivity and high specificity for the diagnosis of tuberculous pleurisy, and meanwhile, can be complementary with the traditional marker adenosine deaminase, and can be used for the auxiliary diagnosis of the tuberculous pleurisy by being combined with the traditional marker adenosine deaminase.

The invention relates to a hydrothorax microparticle metabolite combination, a kit and a method for diagnosing tuberculous pleurisy. The pleural effusion microparticle metabolite composition for diagnosing tuberculous pleurisy comprises phenylalanine, tyrosine, methionine, kynurenine, lauroyl carnitine, glycine-binding chenodeoxycholic acid, phosphatidylcholine with the ratio of 36: 7 and lysophosphatidylcholine with the ratio of 20: 2. The kit for diagnosing tuberculous pleurisy comprises an internal standard substance for detecting the concentration of metabolites in the pleural effusion microparticle sample extraction solution. A combined marker provided by the invention has the characteristics of high sensitivity and high specificity for the diagnosis of tuberculous pleurisy, at the same time, can be complementary with a traditional marker adenosine deaminase, and can be used for the auxiliary diagnosis of the tuberculous pleurisy by being combined with the traditional marker adenosine deaminase.

The invention discloses a traditional Chinese medicine composition for treating tuberculous pleurisy. The traditional Chinese medicine composition is characterized by comprising, by weight, 10-30 parts of Mongolian milkvetch roots, 10-20 parts of nutgrass galingale rhizomes, 10-20 parts of incisory spleenwort herb, 5-15 parts of English walnut, 10-20 parts of fragrant solomonseal rhizomes, 5-15 parts of great burdock fruits, 10-20 parts of rhizome of lalang grass rhizomes, 10-20 parts of prepared rehmannia roots, 10-20 parts of Chinese hibiscus flowers, 5-15 parts of common bletilla tubers, 10-20 parts of common dayflower herb, 10-20 parts of sessile stemona roots, 10-20 parts of notoginseng roots, 5-15 parts of tanakaea omeiensis, 10-20 parts of agaric, 10-20 parts of paper mulberry fruits, 10-20 parts of Japanese ardisia stems and leaves, 10-20 parts of dahurian rose fruits, 10-20 parts of earthworm, 10-20 parts of fructus trichosanthis, 5-15 parts of Chinese corktree barks, 10-20 parts of clam shells and 5-15 parts of ural licorice roots. The traditional Chinese medicine composition has the functions of regulating qi, activating blood, resolving dampness and eliminating phlegm and is scientific in compatibility, remarkable in curative effect, reliable in action and free from side effect.

The invention relates to a traditional Chinese medicinal composition for treating tuberculous pleurisy. The traditional Chinese medicinal composition consists of the following traditional Chinese medicinal raw materials in parts by weight: 10-30 parts of radix codonopsis, 5-25 parts of herba epimedii, 5-25 parts of littleleaf indianmulberry herb, 5-20 parts of szechwan Chinaberry fruits, 5-25 parts of veronicastrum herb, 5-25 parts of herba aristolochiae, 5-25 parts of beautiful sweetgum fruits, 5-20 parts of flos carthami, 5-25 parts of henry clematis root, 5-25 parts of rhizoma curculiginis, 5-25 parts of rhizoma of ophiopogon tonkinensis, 5-20 parts of semen pharbitidis, 5-25 parts of herb of aernaria przewalskii maxim, 5-25 parts of marginate American agave leaf, 5-20 parts of common sowthistle herb, 5-25 parts of cudrania cochinchinensis kudo et masam, 5-25 parts of apricot kernels, 5-20 parts of rhizoma polygoni cuspidati, 5-25 parts of herb of bulbophyllum levinei schltr, 5-25 parts of anderson cirrhopetalum herb, 5-20 parts of pericarpium arecae, 5-25 parts of herba achyranthis asperae and 5-15 parts of liquorice root. The traditional Chinese medicinal composition provided by the invention has functions of tonifying spleen and lung, soothing liver and purging heat, reducing phlegm and removing fluid, promoting circulation of qi and blood, dredging collaterals and alleviating pain, and relieving stranguria by diuresis; and the traditional Chinese medicinal composition, on treating the tuberculous pleurisy, is significant in curative effect and reliable in action.

Tuberculous pleurisy treatment equipment disclosed in the invention comprises a liquid extraction mechanism, and supporting legs are fixedly connected to the four corners of the bottom end of the liquid extraction mechanism; and a bottom plate is arranged at the bottom end of the liquid extraction mechanism, the bottom plate can be placed at the liquid extraction position of a patient, fixing plates are evenly arranged on the periphery of the bottom plate, and the bottom plate can be fixedly connected to the liquid extraction position of the patient, so follow-up liquid extraction work is facilitated; a puncture needle is arranged at the bottom end of the liquid extraction mechanism, so follow-up puncture work is facilitated; and a motor is fixedly connected to the inner side of the liquid extraction mechanism, a first gear is fixedly connected to the output end of the motor, a second gear is connected to the first gear in a meshed mode, a connecting rod is fixedly connected to one side of the second gear, and puncture needles are fixedly connected to the two sides of the connecting rod, so the puncturing motion is slow and precise, and the doctor can conveniently do puncturing motion. The equipment is simple in structure and convenient to operate, and the working efficiency of the doctor is greatly improved.

The invention relates to an external traditional Chinese medicine for treating tuberculous pleurisy with introduction of magnetic heat and belongs to an external traditional Chinese medicine. The external traditional Chinese medicine is prepared from the following crude drugs in parts by weight: 50-100 parts of radix aconite, 50-100 parts of radix aconiti kusnezoffii, 20-30 parts of asarum, 50-80 parts of rhizoma alismatis, 50-100 parts of cassia twig, 50-100 parts of ligusticum wallichii, 30-60 parts of pseudo-ginseng, 30-50 parts of scorpio, 20-30 parts of safflower, 20-30 parts of mirabilite and 15-30 parts of semen strychni. Compared with the prior art, the external traditional Chinese medicine has the advantages of no toxic or side effect, good and rapid treating effect, low cost, convenient administration and the like.

The invention relates to the technical field of medicines, in particular to a molecular marker composition for diagnosing tuberculous pleurisy and application of the molecular marker composition. The molecular marker composition is a composition of miR-4455 (micro Ribonucleic Acid), miR-574-5p (micro Ribonucleic Acid) and miR-4701-3p (micro Ribonucleic Acid). The molecular marker composition is used for preparing a diagnostic reagent or kit for tuberculous pleurisy. According to the invention, a high-throughput microarray chip is used for identifying pleural effusion differential miRNA for distinguishing tuberculous pleurisy and malignant pleural diseases for the first time, and further verification is carried out in an independent sample. The invention provides and identifies the miRNA composition which can be used for identifying and diagnosing focus parts of tuberculous pleurisy and malignant pleural diseases, and the miRNA composition is very important for improving the diagnosis of the tuberculous pleurisy.

The invention relates to the technical field of medicines, in particular to a molecular marker for diagnosing tuberculous pleurisy and application of the molecular marker. The molecular marker is miR-4455 (micro Ribonucleic Acid) or miR-574-5p (micro Ribonucleic Acid) or miR-4701-3p (micro Ribonucleic Acid). The molecular marker is used for preparing a diagnostic reagent or kit for tuberculous pleurisy. The method has the advantages that (1) the identification effect is good; (2) the sensitivity is high; and (3) the specificity is high. And (4) the method is suitable for diagnosis and has high accuracy.