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25 results about "Sinus tracts" patented technology

Surgical instrument for percutaneous transhepatic choledochoscope diagnosis and treatment

A surgical instrument for percutaneous transhepatic choledochoscope diagnosis and treatment is used for establishing a first-stage surgical channel of the percutaneous transhepatic choledochoscope and sinus tract forming of staging surgery, and the surgical instrument system is composed of a surgical working channel sheathing canal and a sinus tract forming drainage tube. The operation working channel sheathing canal is provided with a straight pipe, a bent pipe, an adjustable bending design and an adjustable bending device so as to adapt to all levels of bile ducts to walk, is provided with an anti-squashed pipe body or a variable-diameter material or a variable-diameter device pipe body, a controllable negative pressure connector, an endoscope insertion channel, a sealing cap and an instrument channel, and is provided with an expansion pipe, so that the sheathing canal can be conveniently and smoothly placed into the biliary tract; the sinus tract forming drainage tube body is of a reducing structure, adapts to the volume of a bile duct cavity, is provided with a pigtail-shaped anti-falling device, a fixing line and other anti-falling devices, reduces falling of the drainage tube, is provided with a side hole, can achieve the bile drainage function, is provided with a fixed Luer taper and a movable Luer taper, facilitates imbedding of the sinus tract forming drainage tube in different operation scenes, and is convenient to use. The device is used for improvement and smooth implementation of percutaneous transhepatic choledochoscope surgery.
Owner:刘鹏远

Chronic wound assessment and diagnosis system based on intelligent image recognition

The invention belongs to the technical field of wound assessment, and discloses a chronic wound assessment and diagnosis system based on intelligent image recognition, which comprises an image acquisition module, a region recognition module, a three-dimensional reconstruction module, an assessment module and a treatment scheme recommendation module, the image acquisition module can acquire multi-source heterogeneous chronic wound image data through a unified interface protocol; and the region identification module can segment a wound region from the processed chronic wound image data through a U-Net3 network algorithm and an analysis model, generate an edge weight map, classify necrotic tissues and analyze the trend of the restored sinus tract. The wound area is accurately segmented through the deep learning network, the wound features are intelligently recognized in combination with the image, the accuracy and reliability of evaluation are improved, the dynamic three-dimensional point cloud model is further constructed by applying the binocular vision principle, the spatial form, depth, area, volume, sneaking, sinus tract and flaccidity duct information of the wound is visually displayed, and the evaluation accuracy and reliability are improved. And the subsequent wound assessment effect can be improved.
Owner:BEIJING TONGREN HOSPITAL AFFILIATED TO CAPITAL MEDICAL UNIV

A self-expanding medicine thread and dressing system thereof

The utility model provides a self-expanding medicine thread and a dressing system thereof, which are used to solve the problem that the medicine thread cannot be well fixed in the sinus tract and the dressing is easy to remain in the sinus tract when used with a dressing; a self-expanding medicine thread and a dressing system thereof, wherein the medicine thread body is a solid or hollow cylindrical structure, the surface of the medicine thread has a medicine storage component formed by an inward depression, the medicine thread has a drainage channel, the medicine thread is placed in the sinus tract, the medicine thread is connected to the inside of the dressing, the dressing is placed on the skin around the sinus tract for use, and the surface of the dressing is covered with a biofilm.
Owner:茂名市行来生物科技有限公司

Negative pressure suction device for umbilical sinus tract of newborn

The invention provides a negative pressure suction device for a neonatal umbilical sinus tract, and belongs to the technical field of medical instruments. The device comprises an adhesive tape, the adhesive tape is arranged in a disc shape, and the bottom of the adhesive tape is fixedly connected with a hydrocolloid adhesive ring. During nursing, an adjusting valve is opened, cleaning liquid is added from a feeding hopper and flows into a tank body through guiding, a driving motor is started, a rotating shaft rotates reversely, a stirring plate is driven to stir medicine and liquid medicine, meanwhile, the liquid medicine is turned over through an auger rotating reversely, the mixing effect is enhanced, after stirring is completed, a flow valve is opened, the driving motor drives the auger to rotate forwards, and the medicine and the liquid medicine are mixed. Liquid medicine enters the sinus tract through the drainage pipe, the cleaning catheter and the injection cleaning cavity in sequence to be flushed and applied, the flow speed can be adjusted and controlled during flushing, a child patient is prevented from being stimulated, the independent cavity is adopted, liquid medicine pollution is prevented, frequent pipe replacement is not needed, thorough cleaning and suction are achieved, the sinus tract is effectively nursed, and the infection risk is reduced.
Owner:THE SEVENTH MEDICAL CENTER OF PLA GENERAL HOSPITAL

Filling plugging device for plugging structural heart fistula

InactiveCN119896506AOcculdersMicrosphereFistula
The invention discloses a filling plugging device for plugging a structural heart fistula, which solves the problems that the existing plugging device cannot adapt to the form of a diseased fistula and cannot effectively plug a diseased fistula damaged target area, so that backflow and even falling occur when the diseased fistula damaged target area is plugged, and comprises a plugging guide assembly, a plugging disc group and a self-adaptive plugging device, the plugging guide assembly comprises a plugging guide wire and a plugging composite tube; the self-adaptive plugging device is arranged, the self-adaptive plugging device can inject filling gel according to the sizes of different diseased fistula damaged target areas to achieve flexible adjustment of the expansion volume of the self-adaptive plugging device, after the self-adaptive plugging device injects embolism microspheres / gel, the fistula space can be rapidly filled, and a physical barrier is formed; the device has the functions of self-adaption and complete plugging of irregular sinus tracts, so that healing of surrounding tissues and sealing of fistula are promoted, and meanwhile, the device can also support the plugging disc group, so that it is guaranteed that the plugging disc group stably clamps a target area.
Owner:SHANGHAI FIRST PEOPLES HOSPITAL

Auxiliary tool for sinus tract wound detection and debridement

The invention relates to the technical field of medical instruments, and provides a sinus tract wound probing and debridement auxiliary tool which comprises a base body, a cylindrical body, a guide drill bit, a debridement structure and a driving assembly, the cylindrical body is rotationally connected with the base body through a driving element, the guide drill bit is detachably arranged on the cylindrical body and provided with a first wound debridement surface, and the first wound debridement surface is provided with a second wound debridement surface; the first wound cleaning surface is arranged in the rotating direction of the guide drill bit, the wound cleaning structure is arranged on the cylindrical body and driven by the driving assembly to move in the radial direction of the cylindrical body, the wound cleaning structure is provided with a second wound cleaning surface, and the second wound cleaning surface is arranged in the rotating direction of the guide drill bit. According to the sinus tract debridement device, the trend and form of the sinus tract can be preliminarily explored, the debridement structure is sent into the sinus tract after the sinus tract path is confirmed, necrotic tissue on the inner wall of the sinus tract is accurately removed, therefore, the debridement efficiency and operation safety are remarkably improved, and the sinus tract debridement device is particularly suitable for clinical diagnosis and treatment of sinus tract wound surfaces.
Owner:FIRST HOSPITAL AFFILIATED TO GENERAL HOSPITAL OF PLA

A novel tracheotomy sealing device

ActiveCN116712277BTracheostomy SiteBlood inflow
This invention relates to the field of medical devices, and particularly to a novel tracheostomy occlusion device, comprising an operating table, a fixation plate, an adjustment mechanism, and an execution mechanism. This invention addresses the following problems encountered in the practical use of tracheostomy auxiliary retraction devices: prolonged holding of the retractor by the surgical assistant can cause soreness and lead to shaking of the retractor, which in turn can cause neck movement, affecting the normal progress of the surgery and potentially causing further trauma to the patient's trachea. Furthermore, it cannot effectively manage blood flowing from the neck, which may lead to blood entering the trachea and causing respiratory discomfort, even threatening the patient's life; the portion of the tracheostomy cannula inside the trachea obstructs the airway, affecting the patient's ability to cough up sputum and leading to inaccurate assessments of the patient's coughing ability; and it can easily cause blind sinus tracts to form at the tracheostomy site.
Owner:SHANGHAI CHANGZHENG HOSPITAL

Visual excision mechanism, sneaking sinus tract wound surface cleaning device and cleaning method

The visual excision mechanism comprises a sheathing canal, an image acquisition assembly is installed at the front end of the sheathing canal, a plurality of through holes are formed in the side wall of the front end of the sheathing canal, a cutting blade and a sealing plug are arranged in the front end of the sheathing canal, the cutting blade is located on the side, close to the front end of the sheathing canal, of the through holes, and the sealing plug is located on the side, close to the front end of the sheathing canal, of the cutting blade. The edge of the cutting blade abuts against the inner wall of the sheathing canal, a cutting edge facing the side of the rear end of the sheathing canal is arranged on the edge of the cutting blade, the sealing plug is located on the side, close to the rear end of the sheathing canal, of the through hole, and the sealing plug is in sliding and sealing fit with the inner wall of the sheathing canal. According to the technical scheme, the part needing to be cleaned can be positioned through the image collecting assembly, the device can stretch into the sneaking or sinus tract for operation, the sneaking or sinus tract can be in an open state without additionally arranging a wound for incision, damage is reduced, wound recovery is facilitated, and the recovery period can be effectively shortened.
Owner:MIANYANG CENT HOSPITAL

A breast sinus tract drainage and medicine injection device

A breast sinus drainage medicine injection device, the utility model relates to medical field, the utility model discloses a drainage medicine injection device main part, drainage channel and medicine injection channel, the drainage medicine injection device main part is the hollow structure of upper conical body lower cylinder, and the hollow inner wall is opened to have drainage channel from top to bottom along the circumference, and the medicine injection channel is by the hollow structure in the drainage medicine injection device main part constitutes, the device of the utility model combines drainage and medicine injection into one device, realizes the common operation of drainage and medicine injection, the utility model greatly saves the operation process, reduces the cost, alleviates the discomfort of patient, has market application prospect.
Owner:SHENZHEN LUOHU PEOPLELS HOSPITAL

A method and system for detection and irrigation of deep infective wounds sinuses

The present application relates to a kind of based on deep infectious wound sinus tract detection flushing method and system, belong to medical intelligent detection instrument technical field.Wherein, the method includes: through the micro endoscope of detection flushing device probe connection obtains sinus tract internal image signal, and by real-time transmission to external display device;Terminal application of external display device receives sinus tract internal image signal and is converted into identifiable image information, based on image information self-adapting identification infection area and potential necrotic tissue in sinus tract, and set flushing parameter;Terminal application will flush parameter be transmitted to the wireless receiver of detection flushing device, and control module will be received flush parameter generation control instruction;According to control instruction, adjust flushing pressure and flushing flow to flush sinus tract.It has realized the accurate detection and efficient flushing of deep infectious wound sinus tract, improves the pertinence and effectiveness of flushing.
Owner:XIN HUA HOSPITAL AFFILIATED TO SHANGHAI JIAO TONG UNIV SCHOOL OF MEDICINE

Detection flushing method and system based on deep infectious wound sinus tract

The invention relates to a detection flushing method and system based on a deep infectious wound sinus tract, and belongs to the technical field of medical intelligent detection instruments. The method comprises the steps that a sinus tract internal image signal is obtained through a miniature endoscope connected with a probe of a detection flushing device, and the sinus tract internal image signal is transmitted to an external display device in real time; the terminal application of the external display device receives the sinus tract internal image signal and converts the sinus tract internal image signal into recognizable image information, an infected area and potential necrotic tissue in the sinus tract are recognized in a self-adaptive mode based on the image information, and flushing parameters are set; the terminal application transmits the flushing parameters to a wireless receiver of the detection flushing device, and the control module generates a control instruction according to the received flushing parameters; and flushing the sinus tract by adjusting the flushing pressure and the flushing flow according to the control instruction. Accurate detection and efficient flushing of the deep infectious wound sinus tract are achieved, and the pertinence and effectiveness of flushing are improved.
Owner:XIN HUA HOSPITAL AFFILIATED TO SHANGHAI JIAO TONG UNIV SCHOOL OF MEDICINE

Sinus tract expander system and method of treatment thereby

A tract expander includes a base having a threaded central hole and a plurality of wings. The base and the wings are connected by a plurality of hinges. Each of the plurality of hinges is connected to the base and to a wing of the plurality of wings so that each wing moves relative to the base. A threaded shaft includes a tip. The tip diameter is larger than the threaded shaft diameter and the threaded shaft is configured to screw into the threaded central hole. The threaded shaft is configured to rotate and move the tip toward the hinged base, causing the tops of the plurality of wings to move away from the threaded shaft.
Owner:ABSORBENT LLC

Traditional Chinese medicine ointment for treating chronic osteomyelitis, bone tuberculosis and long-lasting sinus and preparation method thereof

PendingCN122272755Apromote regenerationPromote wound closureWound healingOfficinal
This invention belongs to the field of traditional Chinese medicine external preparation technology, specifically providing a traditional Chinese medicine ointment for treating chronic osteomyelitis, bone tuberculosis, and persistent sinus tracts, as well as its preparation method. The traditional Chinese medicine ointment provided by this invention comprises 3-10 parts of *Achyranthes bidentata*, 5-15 parts of dried ginger, 0.3-1 part of red mercury sulfate, 20-50 parts of calcined gypsum, 4-12 parts of gecko, 5-15 parts of buffalo hide, and 40-100 parts of medicinal ointment base. This invention selects *Achyranthes bidentata*, red mercury sulfate, calcined gypsum, gecko, dried ginger, and buffalo hide as the main ingredients, achieving a combination of warming and cooling properties, and a tonifying and purging effect. It can effectively clear deep pus, necrotic tissue, and dead bone, while also warming and unblocking meridians, improving local blood circulation, promoting wound healing, and reducing the irritation of the medication.
Owner:SHIJIAZHUANG SHENGAN TRADITIONAL CHINESE MEDICINE HOSPITAL CO LTD

A multifunctional measurement and recording ruler for wound burrowing and sinus tracts

This utility model discloses a multifunctional measuring and recording ruler for wound undermining and sinus tracts. It includes a right-angle measuring ruler with connecting measuring rulers fixed at both ends, and a movable measuring ruler at the end of the connecting measuring ruler furthest from the right-angle measuring ruler. It also includes a movable sleeve connected to the top of the right-angle measuring ruler, with a colored pen inside the sleeve. This multifunctional measuring and recording ruler for wound undermining and sinus tracts allows for precise measurement of wound undermining and sinus tracts within the patient's wound using the right-angle measuring ruler, movable measuring ruler, and connecting measuring ruler. When wound depth needs to be measured, the ruler is held vertically, and one end of the movable measuring ruler is inserted into the wound to measure the depth. The depth is then marked with a colored pen according to the different depths of the wound, allowing for accurate and convenient recording of wound undermining and sinus tract size and depth, providing a basis for scientific wound assessment and treatment adjustments.
Owner:THE AFFILIATED SIR RUN RUN SHAW HOSPITAL OF SCHOOL OF MEDICINE ZHEJIANG UNIV

Wound nursing guidance system for remote synchronous video recognition

The invention belongs to the technical field of wound nursing, and discloses a wound nursing guidance system for remote synchronous video recognition, which comprises a video acquisition module, an AR measurement module, a dual-channel calculation module, a data fusion module and a specified suggestion generation module, the video acquisition module is used for performing video data acquisition work; the AR measurement module can dynamically superpose a preset virtual scale template in a corrected video image frame, and the dual-channel calculation module is used for calculating a wound necrosis regression rate and a granulation growth slope through dynamic indexes and quantifying a wound change trend, a sneaking depth and a flaccid paralysis node through a parallel processing mechanism. The AR measurement module augmented reality overlaps a virtual scale, the length, width, area, volume, sneaking, sinus tract and flaccidity duct parameters of a wound are accurately marked in a real-time video stream, meanwhile, the wound necrosis regression rate and the granulation growth slope are calculated through the two-channel calculation module, the wound change trend, sneaking depth and flaccidity duct nodes are quantified, and the wound necrosis regression rate and the granulation growth slope are calculated through the two-channel calculation module. The rate evolution track of the wound of the patient can be conveniently monitored.
Owner:BEIJING TONGREN HOSPITAL AFFILIATED TO CAPITAL MEDICAL UNIV

Sinus tract measurer

The utility model relates to a sinus tract measurer, which belongs to the field of medical instruments, and comprises an angle measurer and two detection rods with scale marks, one end of each detection rod is provided with a sterile contact block, and the other end of each detection rod is provided with a range finder used for measuring the distance between the end parts of the two detection rods; the rod bodies of the two detection rods are connected through a hinge block, the hinge block is slidably connected with the two detection rods, and the hinge block can rotate around the axis of the hinge block relative to the detection rods; the angle measurer is connected to one detection rod in a sliding manner, and the angle measurer is parallel to the two detection rods respectively; the sinus tract width measuring device can be suitable for measuring the width of the deep part of the sinus tract under complex conditions, is simple to operate, can complete sinus tract sampling at the same time so as to facilitate next inspection, and improves the working efficiency.
Owner:JINING NO 1 PEOPLES HOSPITAL (JINING ACAD OF MEDICAL SCI)

L-shaped drainage tube for common bile duct and release method

The invention discloses an L-shaped drainage tube for common bile duct and a release method, and belongs to the technical field of drainage tubes. Comprising an L-shaped pipe which comprises a vertical pipe, a transverse pipe and an elastic bent part connected between the vertical pipe and the transverse pipe, and a drainage opening communicated with the interior of the L-shaped pipe is formed in the arc-shaped outer side of the bent part; the supporting part is inserted into the L-shaped pipe and used for straightening the bent part, the supporting part is connected with a pull wire penetrating out of one end of the vertical pipe, and a guide channel allowing a guide wire to penetrate through is formed in the supporting part. The L-shaped drainage tube can be switched from a straightened state to a bent state by moving the supporting component, can smoothly enter a common bile duct incision from a sinus tract by means of the straightened state, and can form a hook-shaped structure for hooking the common bile duct incision by means of the bent state, so that the drainage tube is prevented from falling off; the L-shaped drainage tube is relatively simple to operate, the difficulty of an implantation operation of the drainage tube can be reduced, the placement time of the drainage tube is shortened, and the operation process is optimized.
Owner:THE THIRD AFFILIATED HOSPITAL OF PLA NAVAL MEDICAL UNIVERSITY

A tubular negative pressure drainage device for orthopedics

The present invention discloses a tubular negative pressure drainage device for orthopedics, which includes an inner tube located inside the wound and an outer tube located outside the wound. The outer tube is located at the top of the inner tube and the inner tube and the outer tube are communicated with each other. A plurality of uniformly distributed side holes are formed on the side wall of the inner tube, and the inside of the inner tube is filled with sponge. The present invention improves the existing aspirator by stuffing the sponge into the inner tube structure. There are side holes on the inner tube, so there will be no problems such as sponge block falling off and difficulty in replacement. The advantage is that the tubular negative pressure drainage device can be safely used for deeper sinus tracts or wounds of the wound and there will be no risk of sponge shedding, etc., and the negative pressure attraction force inside the wound is more uniform. The structure of the present invention is simple. When the sponge needs to be taken out, it can be taken out completely very conveniently, avoiding the generation of dead space, thereby accelerating the healing of the wound.
Owner:XIAN CENT HOSPITAL

In-vitro water absorption structure of sinus tract cannula

The invention provides a sinus tract cannula in-vitro water absorption structure, which relates to the technical field of sinus tract cannula in-vitro water absorption, and comprises a drainage tube, an attachment part, a negative pressure bag, a first one-way valve, a liquid storage bag and a second one-way valve, one end of the drainage tube is used for being inserted into the sinus tract and used for absorbing seepage of the sinus tract, and the attachment piece is connected with the drainage tube and used for being attached to the skin of a patient so that the drainage tube can be detachably attached to the skin and block the sinus tract; the inlet end of the first one-way valve is connected with the end, away from the sinus tract, of the drainage tube, the outlet end of the first one-way valve communicates with an inlet of the negative pressure bag, and the negative pressure bag is constructed to be capable of automatically recovering elasticity and generating negative pressure on the drainage tube when being released after being manually extruded; the inlet end of the second one-way valve is communicated with the outlet of the negative pressure bag, and the outlet of the second one-way valve is detachably communicated with the liquid storage bag. The in-vitro water absorption structure of the sinus tract cannula has the advantages of being simple in structure, low in cost, capable of being managed by a patient autonomously, not limited in activity and the like.
Owner:CHENGDU MILITARY GENERAL HOSPITAL OF PLA

A light guide component and light therapy terminal for sinus tract phototherapy

The present invention provides a light-guiding component and a phototherapy terminal for sinus phototherapy. The phototherapy terminal is composed of a light-guiding component and an optical adapter. The main body of the light-guiding component is made of a first light-transmitting material, which can transmit visible light. The main body of the light-guiding component is a columnar body, and the front end surface of the columnar body is flat. The columnar body is configured to allow light to be irradiated from the side surface and the front end surface of the columnar body. The beneficial effects of the present invention are as follows: (1) The light-guiding component of the phototherapy terminal can penetrate deep into the sinus tract and can evenly transmit light to the surface of the tissue inside the sinus tract; (2) The phototherapy terminal can be suitable for various sinus tract sizes; (3) The light-guiding component in contact with the sinus tract is low-cost, easy to replace, and suitable for disposable use.
Owner:JIANGSU SIGMA MEDICAL TECH CO LTD

Sinus tract detection rod

The utility model provides a sinus tract detection rod, and relates to the technical field of medical instruments. The detection rod comprises a handle, wherein a part of the outer side surface of the handle is concave inwards to form a first accommodating groove; the telescopic rod body comprises a first rod body, a second rod body and a driving mechanism, the first rod body is matched with the first storage groove in a telescopic mode, a second storage groove is formed in the side, away from the bottom of the storage groove, of the first rod body, the second rod body is matched with the second storage groove in a telescopic mode, and the driving mechanism is arranged on the first rod body. The second rod body is used for driving the second rod body to slide relative to the second accommodating groove; and the camera is provided with a light source and is arranged at one end, far away from the first rod body, of the second rod body. The detection rod does not need a large space when being stored, the detection rod is more convenient to put into a medical bag or other carrying containers, and the practicability and the flexibility of the detection rod are improved.
Owner:LUZHOU HOSPITAL OF TRADITIONAL CHINESE MEDICINE

Combined wound flushing negative pressure device

The utility model discloses a combined wound flushing negative pressure device which comprises a dressing layer, a liquid medicine bottle, a liquid inlet pipeline, a liquid outlet pipeline and a negative pressure source. The dressing layer is configured to cover the upper surface of a wound surface or sinus tract of a human body; the liquid medicine bottle is arranged above the dressing layer, and washing liquid medicine is stored in the liquid medicine bottle; the input end of the liquid inlet pipeline is communicated and connected with the liquid medicine bottle, and the output end of the liquid inlet pipeline is fixedly mounted at one end of the upper side surface of the dressing layer; the input end of the liquid outlet pipeline is fixedly installed at the other end of the upper side face of the dressing layer, and the output end of the liquid outlet pipeline is fixedly installed in the liquid collecting tank. The negative pressure source is connected with the output end of the negative pressure pipe in a conducting mode, and the input end of the negative pressure pipe is fixedly installed in the liquid collecting tank. According to the utility model, the negative pressure in a treatment area can be continuously, uniformly and stably improved, and local liquid removal obstacle and accumulation are avoided.
Owner:SHANGHAI YANGPU DISTRICT TRADITIONAL CHINESE MEDICINE HOSPITAL

Closed pressurizing ring

The utility model relates to the technical field of sinus tract radiography, in particular to a closed pressurizing ring. The device comprises a closed ring, Velcro hasps symmetrically arranged on the two sides of the closed ring, and a fixing band used for connecting the two Velcro hasps. The closed ring is provided with a through hole matched with an injector, penetrating grooves matched with the hook-and-loop fastener buckles are symmetrically formed in the two sides of the closed ring, and one end of each hook-and-loop fastener buckle penetrates through one side of the corresponding penetrating groove and then adheres to the other side of the hook-and-loop fastener buckle. And the magic tape hasp is fixedly connected with the fixing band. The sinus port can be tightly combined with the injector, leakage of radiography liquid during sinus tract radiography is avoided, and the whole-course radiography rate of sinus tract radiography lesions is increased.
Owner:SUZHOU WUZHONG PEOPLES HOSPITAL

Sinus therapy tube assembly and sinus therapy device

The present invention relates to the field of medical device technology, and provides a sinus treatment tube assembly and a sinus treatment device. The sinus treatment tube assembly includes a tube body and a plasma generator. The tube body includes a tube body and a treatment end connected to each other, the treatment end being suitable for insertion into a sinus tract. The plasma generator is located at the treatment end and is suitable for connecting to a power module. The plasma generator includes a stacked negative electrode layer, a dielectric barrier layer, and a positive electrode layer, or the plasma generator includes a coplanar positive electrode and a negative electrode. The sinus treatment tube assembly provided by the present invention not only has drainage and flushing functions, but also has the additional function of plasma treatment, which can exert a strong bactericidal effect and promote wound healing.
Owner:BEIJING MEDICAL PLASMA LABORATORY TECHNOLOGY CO LTD

Application of regulating Notch / Wnt signal channel to block formation of hidradenitis suppurativa active sinus tract

The invention discloses an application of regulating and controlling a Notch / Wnt signal channel in blocking formation of hidradenitis suppurativa active sinus tracts, and further discloses an application of regulating and controlling the Notch / Wnt signal channel in screening a medicine for blocking formation of the hidradenitis suppurativa active sinus tracts. The screening is realized by detecting the influence of a candidate substance on the activity of the Notch / Wnt signaling pathway. The influence on the activity of the Notch / Wnt signal path comprises activation of the Notch signal path and / or inhibition of the Wnt signal path. According to the invention, the S0 epithelial cell subgroup and a molecular marker combination (such as COL4A1, LAMC2, ITGA6, MMP1 and the like) specifically expressed by the S0 epithelial cell subgroup are identified, and the key regulation function of a Notch / Wnt signal channel in the subgroup is defined, so that a clear direction and a target spot are provided for deeply researching a molecular mechanism formed by a sinus tract; and a key theoretical basis and a feasible technical path are provided for subsequent establishment of a targeted drug screening system and discovery of effective candidate substances.
Owner:RENJI HOSPITAL AFFILIATED TO SHANGHAI JIAO TONG UNIV SCHOOL OF MEDICINE