84 results about "Necrotic tissue" patented technology

The invention relates to a traditional Chinese medicine composition for treating burns and scalds, which is prepared from spur root and jade grape root according to a certain compatibility, and has the following effects: pain relieving: aching feeling is relieved or even disappears within 15 minutes; convergence: seepage of tissue fluid can be stopped within two hours; bacteriostasis: after the ointment is used, wounds which are just burnt and scalded or fester for several months can be gradually healed, and necrotic tissues can scab and fall off; skin grafting is not needed for burn and scald patients, scar tissue hyperplasia is avoided, and the disability rate of the patients is greatly reduced.

The invention discloses a fruit and vegetable grafting wound healing nutrient solution containing polysaccharide complex enzyme and a preparation method, belongs to the technical field of agricultural biochemical preparations, and aims to solve the technical problems of low removal efficiency of necrotic tissues at grafting wounds and high risk of microbial infection. According to the technical scheme, the nutrient solution is characterized by being prepared from the following raw material components in parts by weight: 0.3 to 0.8 part of polysaccharide, 1 to 5 parts of cellulase, 0.5 to 2.5 parts of pectinase, 1 to 5 parts of glycerol and 90 to 100 parts of water. Wherein the pH value of the nutrient solution is adjusted to 5.0-6.5 by using a phosphate buffer agent, the polysaccharide is composed of chitosan and sodium alginate, the mass ratio of the chitosan to the sodium alginate is 1: 0.5-1: 2, the activity of cellulase in the nutrient solution is 100-500 U / mL, and the activity of pectinase in the nutrient solution is 50-250 U / mL. The nutrient solution is mainly used for promoting fruit and vegetable grafting wound healing, and application verifies that the nutrient solution can effectively improve wound healing quality and reduce infection risk in the grafting process of fruits and vegetables such as cucumbers, eggplants, peppers, tomatoes, litchis and oranges, and has a good application effect.

The invention belongs to the technical field of wound assessment, and discloses a chronic wound assessment and diagnosis system based on intelligent image recognition, which comprises an image acquisition module, a region recognition module, a three-dimensional reconstruction module, an assessment module and a treatment scheme recommendation module, the image acquisition module can acquire multi-source heterogeneous chronic wound image data through a unified interface protocol; and the region identification module can segment a wound region from the processed chronic wound image data through a U-Net3 network algorithm and an analysis model, generate an edge weight map, classify necrotic tissues and analyze the trend of the restored sinus tract. The wound area is accurately segmented through the deep learning network, the wound features are intelligently recognized in combination with the image, the accuracy and reliability of evaluation are improved, the dynamic three-dimensional point cloud model is further constructed by applying the binocular vision principle, the spatial form, depth, area, volume, sneaking, sinus tract and flaccidity duct information of the wound is visually displayed, and the evaluation accuracy and reliability are improved. And the subsequent wound assessment effect can be improved.

The invention relates to the technical field of medical instruments, and provides a sinus tract wound probing and debridement auxiliary tool which comprises a base body, a cylindrical body, a guide drill bit, a debridement structure and a driving assembly, the cylindrical body is rotationally connected with the base body through a driving element, the guide drill bit is detachably arranged on the cylindrical body and provided with a first wound debridement surface, and the first wound debridement surface is provided with a second wound debridement surface; the first wound cleaning surface is arranged in the rotating direction of the guide drill bit, the wound cleaning structure is arranged on the cylindrical body and driven by the driving assembly to move in the radial direction of the cylindrical body, the wound cleaning structure is provided with a second wound cleaning surface, and the second wound cleaning surface is arranged in the rotating direction of the guide drill bit. According to the sinus tract debridement device, the trend and form of the sinus tract can be preliminarily explored, the debridement structure is sent into the sinus tract after the sinus tract path is confirmed, necrotic tissue on the inner wall of the sinus tract is accurately removed, therefore, the debridement efficiency and operation safety are remarkably improved, and the sinus tract debridement device is particularly suitable for clinical diagnosis and treatment of sinus tract wound surfaces.

The application discloses a general surgery operation trauma nursing device and belongs to the technical field of medical devices, which comprises a body, and a separation component is arranged on the inside and outside of an operating table, wherein the separation component comprises a collecting frame which is inserted into the operating table, a scraping ring is fixedly connected to the inside of the collecting frame, a protective cover is arranged in the operating table, and a driving motor is arranged in the protective cover. The magnetic block ring is arranged to adsorb metal foreign matters, and the rotating disc accelerates the flow of liquid after rotation, so that the foreign matters and necrotic tissues are quickly separated. Since the magnet ring can adsorb the metal foreign matters during rotation, the foreign matters and necrotic tissues are separated, the foreign matters carrying the necrotic tissues are prevented from sinking into the physiological saline and being difficult to separate, and the rotating disc only accelerates the flow speed of the physiological saline during stirring of the physiological saline, so that the over-dissolution of the necrotic tissues is reduced, and the separation effect of the foreign matters and the necrotic tissues is guaranteed.

The invention relates to the technical field of nursing materials, and discloses an oral and maxillofacial nursing drainage apparatus, the oral and maxillofacial nursing drainage apparatus comprises a main pipe, an auxiliary pipe and a clamping sleeve which are integrally formed, the main pipe is provided with a drainage assembly, the drainage assembly comprises two sets of conical pipes, and the large ends of the two sets of conical pipes are fixedly connected with the two ends of the main pipe respectively. According to the oral and maxillofacial nursing drainage apparatus, by arranging the drainage assembly, when the drainage head is placed on a wound surface, a solid-liquid mixture can be drained, when the drainage cylinder is placed on the wound surface, the drainage cylinder is matched with the drainage hole to drain a liquid drainage object, natural negative pressure drainage force is generated through the height difference, and the drainage object enters the drainage collection bin through the hose, the conical pipe, the main pipe and the bent pipe; the sealing dressing is matched to improve the sealing performance, the auxiliary tube and the threaded locking valve are matched to facilitate drainage object removal, wound surface liquid accumulation, hematocele or necrotic tissue can be sucked out actively under the stable negative pressure, saliva pollution is isolated through the sealing design, and the drainage amount is measured through scale marks.

The present application relates to the technical field of clinical nursing, and specifically discloses a clinical nursing wound cleaning device, which comprises a negative pressure wound therapy instrument, and further comprises a negative pressure adsorption mechanism arranged on the negative pressure wound therapy instrument and used for adsorbing and cleaning a wound surface of a patient, and has at least the following beneficial effects: the negative pressure adsorption mechanism can be closely attached to the wound surface by means of an attached cover, thereby avoiding negative pressure leakage, improving adsorption efficiency and debridement effect, and using a negative pressure pump can efficiently adsorb and collect wound secretions and necrotic tissues, ensure complete debridement, and replace traditional mechanical debridement with negative pressure adsorption, which causes less damage to the wound surface and newly generated granulation tissue, significantly reduces the pain of the patient, and balances debridement effect and nursing safety, thereby meeting the fine cleaning requirements of various wounds in clinical practice.

The invention provides a necrotic tissue removing clamp under a choledochoscope, which relates to the technical field of medical instruments and comprises a first removing tube, a second removing tube and a plurality of barbs. The first clearing pipe comprises a first pipe body and a plurality of clearing elastic pieces, and the clearing elastic pieces are connected to one end of the first pipe body. The second cleaning pipe is coaxially and movably arranged in the first cleaning pipe in a penetrating mode. The barbs are arranged on the clearing elastic pieces and the second clearing pipe respectively. When the first clearing pipe is located in the instrument channel, the clearing elastic pieces are restrained by the instrument channel in the radial direction to be in a folded state. And when the first clearing pipe extends out of the end part of the instrument channel, the plurality of clearing elastic sheets are released from the radial constraint and are automatically and radially expanded. According to the invention, the cleaning efficiency can be effectively improved, the one-time cleaning success rate can be effectively improved, the problems of slippage and untight closing are solved, in addition, the device also has the advantage of simplicity and convenience in operation, and can be effectively adapted to a minimally invasive environment.

The utility model discloses a drainage tube fixing patch, and belongs to the technical field of drainage tube fixing patches. The drainage tube fixing patch comprises an upper patch body and further comprises a fixing block, the fixing block is connected with the lower end of the upper patch body, a sleeve is arranged in the fixing block, a drainage tube is arranged in the sleeve, and a first lower patch body and a second lower patch body are arranged on one side of the upper patch body. In order to solve the problem that after a drainage tube is fixed, drainage necrotic tissues of a human body are easily blocked at a bending point, so that the drainage tube is unsmooth, one end of the drainage tube firstly penetrates through a sleeve, then penetrates through gauze and finally enters the abdominal cavity of the human body, an upper patch is firstly pasted on the body surface by a person, and then a first lower patch and a second lower patch are respectively pasted on the body surface; then, the person adheres the first adhesive tape and the second adhesive tape to the side face of the drainage tube in a winding mode, so that the position of the drainage tube is fixed, the drainage tube enters the abdominal cavity from the outside without bending, and the situation that the drainage tube is unsmooth is avoided.

The invention discloses a traditional Chinese medicine composition for preventing and treating haemorrhoids, a medicine and a preparation method thereof, the traditional Chinese medicine composition is composed of 10-30 parts of red halloysite, 10-30 parts of medical stone and 10-30 parts of calamine, and the active ingredient of the medicine is the traditional Chinese medicine composition. The traditional Chinese medicine composition disclosed by the invention has the effects of astringing intestines and stopping bleeding, detoxifying and removing stasis, removing necrotic tissue and promoting granulation, and relieving itching and astringing sores, and can achieve the treatment effect on haemorrhoids by relieving anus swelling, improving capillary permeability, eliminating inflammation, astringing ulcer wounds and accelerating wound healing. Few medicines are used and the curative effect is obvious.

The invention provides a sorbitol and mannitol flushing fluid for urinary surgery. The invention relates to a freeze-dried powder injection, which comprises 20 to 50 grams of sorbitol, 10 to 30 grams of mannitol, 5 to 10 grams of sodium bicarbonate and 0.5 to 2 grams of sodium citrate in every 1000 milliliters of the freeze-dried powder injection, and the pH value of the freeze-dried powder injection is adjusted to 7.2 to 7.4. The preparation method comprises the following steps: heating distilled water to 80 DEG C, sequentially adding the components, continuously stirring until the components are completely dissolved, cooling to room temperature, fixing the volume to 1000ml, adjusting the pH value by using a 5mol / L sodium hydroxide solution, finally sterilizing by using a 0.22-micron microporous filter membrane, and packaging in a sterilized glass bottle. The flushing fluid can effectively dissolve blood clots, stones and necrotic tissues in an operation field by utilizing the high osmotic pressure characteristics of the sorbitol and the mannitol, so that the operation field is kept clear. The flushing fluid disclosed by the invention shows an excellent flushing effect and good safety in urinary surgery operations such as transurethral bladder tumor electrocision, flexible ureteroscope calculus removal and the like.

A method of endodontic therapy with improved disinfection and ablation characteristics may feature the use of an alcohol or polyol-based indocyanine green (ICG) solution with a laser system that emits a wavelength within the maximal absorption range of ICG. By matching the dye and laser output, radiant energy use is maximized for efficient ablation and disinfection of treated tissues. Also, the use of an alcohol or polyol as a solvent for the ICG solution increases the inherent disinfection qualities of the solution itself. In one embodiment, the prepared canal is flooded with the ICG solution and the laser activates with the laser fiber inserted into the solution. In an alternate embodiment, the solution is mostly removed prior to activation of the laser, but only after necrotic tissue has been stained.

The application discloses a kind of auxiliary diabetic foot ulcer grading wound image analysis method, it is related to medical image analysis technical field, can solve how to based on single frame optical image automatically, accurately distinguish the problem of solid-state necrotic tissue and liquid pus exudate with visual feature highly similar in diabetic foot ulcer wound, including: determining ulcer lesion area in input image, and determine lesion equivalent diameter;Determine the first point set that all tissue sample points to be classified in ulcer lesion area constitute, and the second point set that all potential convergence positions in ulcer lesion area constitute;According to lesion equivalent diameter, first point set and second point set, construct total cost matrix;Total cost matrix is solved using preset matching algorithm, each point in first point set is classified as liquid attribute point or solid attribute point;According to the number of being classified as liquid attribute point and first quantity determine liquid component proportion, compare with preset threshold value, output diabetic foot ulcer grading result.

The traditional Chinese medicine preparation device comprises a tank body, a feeding pipe is arranged at the top of the tank body, a discharging pipe is arranged at the bottom of the tank body, a rotating cylinder is rotationally installed at the center of the top of the tank body, and a main shaft extending into the tank body is arranged in the rotating cylinder; a rotary drum is fixedly mounted at the upper end of the main shaft, a rotary disc is rotatably mounted at the end, close to the top in the tank body, of the main shaft, and a sleeve penetrating through the rotary drum is fixedly mounted at the upper end of the rotary disc. Scattering of the dispersing plate, coarse crushing of the crushing assembly, fine grinding of the grinding cavity, material distribution of the material homogenizing assembly, homogenizing of the mixing assembly and finally discharging from the discharging pipe are conducted in sequence, continuous operation of feeding, processing and discharging is achieved, the production period is shortened through the process, impurity introduction and material loss in the manual transferring process are avoided, the finished product hygiene and the material utilization rate are improved, and the production cost is reduced. And standardized production requirements are met.

The invention discloses a traditional Chinese medicine for treating haemorrhoids, which comprises the following raw materials: borneol, centipeda minima, pepper, radix sophorae flavescentis, seaweed, rheum officinale, radix curcumae, radix angelicae, perilla leaf, mint, prepared myrrh and realgar. The composition design, pathogenesis and pathology distinguishing and channel tropism logic are strict and reasonable, and the effects of relieving pain and stopping bleeding, softening hardness to dissipate stagnation, removing slough and promoting tissue regeneration and treating both symptoms and root causes can be achieved when hemorrhoids are treated. The traditional Chinese medicine composition has the advantages of simple preparation process, quick effect of relieving pain and stopping bleeding and short curing time, can be used for treating hemorrhoids at different disease positions such as internal hemorrhoids, external hemorrhoids and mixed hemorrhoids, and can also be used for treating constipation, rectocele, anal abscess, rectal cancer, anal eczema and other related anorectal diseases.

The invention belongs to the technical field of biological medicine, and relates to a polypeptide composition as well as a preparation method and application thereof. According to the polypeptide composition, sodium carboxymethyl cellulose and xanthan gum are adopted as raw materials, pH-sensitive hydrogel capable of being rapidly cured at a wound is prepared, the hydrogel wraps polypeptide active ingredients and can be rapidly cured to form a layer of hydrogel film after being smeared on the affected part, the hydrogel film firmly covers the skin of the affected part, the environment of the affected part is kept stable and moist, and the wound healing effect is good. Necrotic tissues are softened, scabbing is reduced, active polypeptide components are continuously released, the action time is prolonged, and the repair period is shortened. The polypeptide component in the composition is compounded by arginine / lysine polypeptide, hexapeptide-11, palmitoyl tetrapeptide-7 and palmitoyl tripeptide-1, the four polypeptides construct an anti-inflammatory, repair-promoting and anti-scar complete-cycle repair system through multi-target and multi-stage synergy, and the composition is suitable for various skin wound scenes.

This invention discloses an integrated device for foot wound care and treatment in diabetic foot, relating to the field of medical device technology. It includes: a cleaning mechanism for removing necrotic tissue, bacteria, and secretions adhering to the wound surface; and a medication application mechanism that maintains contact between the sole of the foot and the medication layer, subsequently adhering an adhesion layer to the ankle. This invention achieves an integrated design for the foot wound care and treatment process, organically combining cleaning, disinfection, dressing changes, and auxiliary treatments within a single device. Medical staff no longer need to frequently switch between various instruments to complete different care and treatment steps, greatly simplifying the process. This saves time and effort while significantly improving overall work efficiency, providing higher quality and efficiency assurance for the care and treatment of diabetic foot patients, promoting wound healing, and accelerating the recovery process.

The present application relates to a kind of based on deep infectious wound sinus tract detection flushing method and system, belong to medical intelligent detection instrument technical field.Wherein, the method includes: through the micro endoscope of detection flushing device probe connection obtains sinus tract internal image signal, and by real-time transmission to external display device;Terminal application of external display device receives sinus tract internal image signal and is converted into identifiable image information, based on image information self-adapting identification infection area and potential necrotic tissue in sinus tract, and set flushing parameter;Terminal application will flush parameter be transmitted to the wireless receiver of detection flushing device, and control module will be received flush parameter generation control instruction;According to control instruction, adjust flushing pressure and flushing flow to flush sinus tract.It has realized the accurate detection and efficient flushing of deep infectious wound sinus tract, improves the pertinence and effectiveness of flushing.

Embodiments disclosed herein generally relate to identifying necrotic tissue in a multiplex immunofluorescence image of a sample section. In particular, aspects of the present disclosure relate to: accessing a multiplex immunofluorescence image of a sample section comprising a first channel for a nuclear marker and a second channel for an epithelial tumor marker, wherein the sample section comprises one or more necrotic tissue regions; providing the multiplex immunofluorescence image to a machine learning model; receiving an output of the machine learning model, the output corresponding to a prediction that the multiplex immunofluorescence image comprises one or more necrotic tissue regions at one or more particular portions of the multiplex immunofluorescence image; generating a mask for subsequent image processing of the multiplex immunofluorescence image based on the output of the machine learning model; and outputting the mask for the subsequent image processing.

A system for treatment of wounds consists of a treatment housing, a fluid delivery mechanism for supplying debridement fluids to the wound treatment area, an evacuation mechanism for evacuation of debris from the treatment chamber. A handheld device is connected to the treatment housing, wherein its interior accommodates a laser source, a scanning device, an image recording device and at least one sensor / detector, a control unit having a microprocessor for controlling operation of the system. The sensors detect concentration of various substances in the wound, and microprocessors analyze data obtained by the sensors and generate signals to adjust parameters of the laser, the liquid dispensing nozzles and the suction outlet to optimize removal of necrotic tissue, to promote wound healing.

The invention relates to the technical field of medical instruments, and provides a debridement device for an exposed wound surface of an implant after a skull plasty, the debridement device comprises a handle, a tube body, a debridement piece, a control mechanism and a flushing / negative pressure adsorption assembly, the tube body is rotatably connected with the handle, the debridement piece is detachably arranged at the far end of the tube body, the debridement piece can deviate relative to the radial direction of the tube body, and the control mechanism is arranged on the control mechanism. The control mechanism is operably arranged at the near end of the tube body, deformation holes distributed in the axial direction of the tube body are formed in the tube body, and the control mechanism is connected with the deformation holes through a transmission inhaul cable so that operation of an operator on the control mechanism can be synchronously transmitted to the deformation holes. The device can adapt to the curved surface appearance and the porous structure of skull implants such as a titanium mesh and a titanium plate, so that the debridement piece can be effectively attached to the inner side surface of the implants in the operation process and go deep into pores of the implants, attachments (such as fester, blood clots and necrotic tissues) are efficiently and thoroughly removed, and the debridement quality and the operation effect are remarkably improved.

The utility model provides a femoral head necrotic tissue cleaning device, which belongs to the technical field of medical instruments, and aims to solve the problem that the cleaning range is limited when the necrotic tissue is cleaned by the conventional device, the femoral head necrotic tissue cleaning device comprises a cleaner and a sleeve, the cleaner is movably arranged in the sleeve in a penetrating manner, and the cleaner comprises a mounting cylinder, a scraper and an adjusting component, the scraper is movably connected to the far end of the mounting cylinder, the adjusting assembly is connected to the mounting cylinder and movably connected with the scraper, the range of the scraper for removing the femoral head necrosis area is adjusted by means of opening and closing of the operating pliers similar to a scissor structure, the removing range of the necrosis bone tissue area is enlarged, and the removing efficiency of the necrosis bone tissue is improved; the operation time is shortened, and the device has great prospects and popularization value clinically.

The utility model discloses a medical anti-slip, convenient flushing, pressure measurable single 'J' tube, which comprises a single J tube annular part and a single J tube main body, the right end of the single J tube main body is provided with the single J tube annular part, the left end of the single J tube main body is provided with a single J tube side branch, the lower side of the single J tube side branch is provided with a drainage bag, and the drainage bag is provided with a drainage hole. The single J tube collateral branch is connected with the drainage bag through a collateral branch flushing sampling end, and is used for a patient subjected to ureteral skin stoma pelvis ureteral drainage after radical bladder resection, the postoperative ureteral stent can be better prevented from slipping, the postoperative ureteral stent can be conveniently flushed, necrotic tissues and foreign matters can be flushed out in time, flushing and pressure measurement are facilitated due to sufficient drainage, and the drainage effect is good. Risks of hydronephrosis and exuresis caused by blockage of the ureteral stent after the operation of a patient are reduced, sampling after the operation is convenient, the condition of intrarenal pressure of the patient is known in time, and the problems that the ureteral stent slips easily and is difficult to wash in the perioperative period are solved.

This invention belongs to the field of traditional Chinese medicine external preparation technology, specifically providing a traditional Chinese medicine ointment for treating chronic osteomyelitis, bone tuberculosis, and persistent sinus tracts, as well as its preparation method. The traditional Chinese medicine ointment provided by this invention comprises 3-10 parts of *Achyranthes bidentata*, 5-15 parts of dried ginger, 0.3-1 part of red mercury sulfate, 20-50 parts of calcined gypsum, 4-12 parts of gecko, 5-15 parts of buffalo hide, and 40-100 parts of medicinal ointment base. This invention selects *Achyranthes bidentata*, red mercury sulfate, calcined gypsum, gecko, dried ginger, and buffalo hide as the main ingredients, achieving a combination of warming and cooling properties, and a tonifying and purging effect. It can effectively clear deep pus, necrotic tissue, and dead bone, while also warming and unblocking meridians, improving local blood circulation, promoting wound healing, and reducing the irritation of the medication.

1. Name of the product in this design: Ultrasonic debridement machine. 2. Purpose of this design: To clean wounds, remove necrotic tissue, and improve the wound healing environment. 3. The key design feature of this product is its shape. 4. The image or photograph that best illustrates the design's key points: a 3D model.

The invention discloses a foot wound nursing and treatment integrated device for diabetic feet, and relates to the technical field of medical apparatus and instruments, the foot wound nursing and treatment integrated device comprises a cleaning mechanism which can clean some necrotic tissues, bacteria and secreta impurities attached to a wound; the medicine applying mechanism is used for keeping the sole to be in contact with the medicine layer, and then the adhesion layer can be adhered to the ankle position. According to the device, the integrated design of the foot wound surface nursing and treatment process is achieved, cleaning, disinfection, dressing change and auxiliary treatment are organically integrated in the same device, medical staff do not need to frequently replace and use various instruments for completing different nursing and treatment steps, the nursing and treatment process is greatly simplified, and the nursing and treatment efficiency is improved. While time and energy are saved, the overall working efficiency is remarkably improved, higher quality and efficiency guarantee is brought to nursing and treatment work of diabetic foot patients, healing of diabetic foot wounds is promoted, and the rehabilitation process is accelerated.

Embodiments disclosed herein generally relate to identifying necrotic tissue in a multiplex immunofluorescence image of a slice of specimen. Particularly, aspects of the present disclosure are directed to accessing a multiplex immunofluorescence image of a slice of specimen comprising a first channel for a nuclei marker and a second channel for an epithelial tumor marker, wherein the slice of specimen comprises one or more necrotic tissue regions; providing the multiplex immunofluorescence image to a machine-learning model; receiving an output of the machine-learning model corresponding to a prediction that the multiplex immunofluorescence image includes one or more necrotic tissue regions at one or more particular portions of the multiplex immunofluorescence image; generating a mask for subsequent image processing of the multiplex immunofluorescence image based on the output of the machine-learning model; and outputting the mask for the subsequent image processing.

The invention discloses a multifunctional wound treatment and cleaning device, relates to the technical field of medical apparatuses and instruments, and aims to solve the technical problem that the current wound cleaning equipment usually realizes a debridement function through single water flow and is difficult to meet the use requirements except for debridement. Through the deformable assembly and the cleaning driving assembly, in the flushing state, the flushing structure outputs stable water flow pressure, and foreign matter and necrotic tissue can be effectively removed. When the water mist state is switched to, the water mist structure can penetrate into the wrinkles of the wound through water mist to clean the wrinkles of the wound, can promote wound healing through a moist environment, and is particularly suitable for wound surfaces needing continuous moist nursing such as burns and large-area scratches. Through free switching of the two modes, the device can meet the complete-cycle wound treatment requirement from debridement to repair, and the clinical application value is remarkably improved.

The invention discloses a wound flushing assembly for diabetic foot infection nursing, and relates to the technical field of diabetic foot nursing. A wound surface flushing assembly for diabetic foot infection nursing comprises a supporting rod, the top of the supporting rod is movably connected with an adjusting cylinder in a sleeving mode, a sealing box is fixedly installed at the top of the adjusting cylinder, and a sewage draining pipe is fixedly installed at the bottom of one side of the sealing box. The foot of a patient is isolated from the outside by arranging the sealing structure, an independent debridement space is formed, aerosol containing pathogenic bacteria generated during flushing is prevented from polluting the surrounding environment, the device is particularly suitable for diabetic foot patients infected by multiple drug-resistant bacteria, and the cross infection risk in a hospital is reduced; meanwhile, the stable sealing state can reduce the contact area of the wound surface and air, the oxidation speed of necrotic tissues is delayed, and the debridement environment is kept relatively clean.

The invention provides an extraction method of autologous neutrophil physical activation multi-component protein and application of the autologous neutrophil physical activation multi-component protein in chronic infectious wound treatment. According to the method, the neutrophil is physically activated, so that chemical irritant residues are avoided, and the compound protein component rich in MPO, NE, Lysozyme, Lactoferrin and other multiple bactericidal proteins is obtained. And the protein component is directly delivered to the basal part of the chronic wound surface in a multi-point and layered injection mode (1 time / 3 days, 250 [mu] L / time) in a focus area, so that bacterial biofilms and necrotic tissues can be effectively removed, wound debridement, cell migration and matrix remodeling are promoted, and the healing of the chronic infectious wound surface is accelerated. The method disclosed by the invention has the advantages of autologous source, good biocompatibility, accurate treatment and the like, is particularly suitable for treating chronic infectious wounds such as diabetic foot ulcer and the like, and provides a new thought for treating the chronic wounds.