87 results about "Wound skin" patented technology

The invention relates to a cell-free compound artificial skin and a preparation method thereof. The compound skin of the invention is provided with a double layer structure of a dermis layer and an epidermis layer; the dermis layer is a loose porous structure made of extracellular matrix; gel-shaped epidermis-like materials are coated on the upper surface of the dermis layer to solidify, thus forming the epidermis layer, and the epidermis layer is inserted into a void structure of the surface of the dermis layer; compared with the existing skin substitutes, the skin of the invention has the functions of promoting the regeneration of wound skin, enhancing the elasticity, flexibility and mechanical wear resistance of the skin after the wound is healed, reducing the scar proliferation, controlling the contracture, improving the success rate of skin implantation and improving the healing quality; the skin of the invention has a sustained release function and can make individual-based treatment for different diseases by releasing different drugs and being directly applied to the treatment of skin defects caused by inflammations, ulcers, burn wounds and iatrogenic causes; the epidermis layer and the dermis layer are embedded together organically with a tight structure; the shapes, sizes and the thicknesses of the skin can be prepared according to specific requirements. The skin of the invention has wide sources of preparation materials, simple production process, short production period, long period of product storage and convenient transportation.

The present invention refers to an Integrated Implant System constituted as a gel-matrix-cells integrated system, that allows providing implants in a brief time period, for covering a great skin extension to be treated, with a successful acceptance in patients with burns, chronic damage or wound skin, needing of a skin grafting.

The present invention relates to novel hydrophilic adhesive compositions, characterised in that they comprise a thermoplastic elastomer of poly(styrene-olefin-styrene) block copolymer type, a tackifying product, a liquid plasticizer, water and un amphiphilic copolymer. The invention also relates to the use of these novel hydrophilic adhesive compositions as adhesives for fixing any type of product, and notably products for medical, dermatological or cosmetological purposes, which come into contact with a wound, the skin or the mucous membranes.

The invention discloses a surgical dressing material with a cooling property and a preparation method of the surgical dressing material, belongs to the technical field of medicinal materials, and aims to solve the problems of providing a surgical dressing material which has a cooling effect and a wound protection function as well in the use process, and a preparation of the surgical dressing material. The surgical dressing material consists of the following components in parts by weight: 65-85 parts of copolyether, 10-20 parts of isocyanate, 20-40 parts of a chain extender, 40-60 parts of a foaming agent, 1-5 parts of a surfactant, 1-5 parts of an opening forming agent and 20-35 parts of a phase change agent. The surgical dressing material has good water absorption and air permeability, various testing results meet national technical requirements on surgical dressing materials, and meanwhile wound skin heat can be absorbed in the use process, so that discomfort of patients can be alleviated.

The invention discloses a spina gleditsiae extract hydrogel patch and a preparation method thereof, and belongs to the technical field of pharmaceutic preparation. The spina gleditsiae extract hydrogel patch is formed by mixing a spina gleditsiae extract and a blank hydrogel substrate; the phenolic acid compound contend of the spina gleditsiae extract is 6-7 mg/ml; the blank hydrogel substrate is formed by stirring and mixing an oil phase and a water pahse, wherein the weight ratio of the oil phase and the water phase is 50-60:100; the components of the oil phase are glycerin, polyacrylic acid, dihydroxyaluminum aminoucetate, and azone; the components of the water phase are water, carboxymethylcellulose sodium, tartaric acid, EDTA-2Na, and titanium dioxide. The spina gleditsiae extract hydrogel patch of the invention has simple substrate prescription, high water content, and strong affinity, is reliable and stable, has no irritation to skin, has good anti-infection drug effect activity, allows convenient addition of various Chinese herbal medicine extracts, and is widely applicable to aspects such as surgical wounds, general wounds, skin infection, cosmetology and skin beautification, and the like.

The invention discloses a collagen dressing, which is composed of a collagen complex liquid and nonwoven cloth impregnated in collagen. The collagen complex liquid is composed of following componentsin parts by weight: 1 to 10 parts of C3 polyol, 0.01 to 0.5 part of recombinant human-derived collagen, 0.1 to 0.5 part of lactobionic acid, 0.05 to 0.2 part of gluconolactone, 0.2 to 0.5 part of antiseptic, and the balance being injection water, wherein the total parts by weight is 100. The invention also provides a preparation method of the collagen dressing. The collagen dressing is little irritant to the skin, is mild, has a moisturizing function, and can effectively promote the metabolism of cells and healing of wound skins.

The invention belongs to the field of medical dressings, and particularly relates to a liquid dressing and a preparation method thereof. The liquid dressing is prepared from glycerin, polyethylene glycol, sodium hyaluronate, trehalose and purified water. The liquid dressing prepared according to the technical scheme is safe and non-irritant, can protect a wound from being infected by external pollutants and bacteria, and meanwhile has effects of moisturizing and repairing wound skin.

The invention belongs to the field of sewing devices, in particular to a suturing device for wound emergency nursing. An existing suturing device is inconvenient to draw wound skin together, and the position of the arm of the patient cannot be fixed. Proposed now is the following scheme, the device comprises a fixed seat, a fixing groove is formed in the top of the fixed sea, sliding holes are formed in the inner walls of the two sides of the fixing groove, movable seats are mounted in the two sliding holes in a sliding manner, connecting grooves are formed in the sides, close to each other, of the two movable seats, sliding bases are slidably mounted in the two connecting grooves correspondingly, rotating grooves are formed in the sides, close to each other, of the two sliding bases correspondingly, rotating blocks are rotatably mounted in the two rotating grooves correspondingly, pulling plates are fixedly mounted on the sides, close to each other, of the two rotating blocks correspondingly, and non-slip mats are fixedly connected to the sides, close to each other, of the two pulling plates correspondingly. The suturing device is reasonable in structure and convenient to operate,wound skin can be conveniently drawn together through the suturing device, and the position of the arm of a patient can also be fixed.

The invention belongs to the field of medical dressings, and particularly relates to a liquid dressing for skin wound repair and a preparation method and application thereof. The liquid dressing for skin wound repair is prepared from the following raw materials in percentage by weight: 0.05 to 0.2 percent of D-(+)-trehalose dihydrate, 0.05 to 0.2 percent of hyaluronate, 1 to 5 percent of butanediol, 1 to 5 percent of glycerol and the balance of purified water. Experimental results show that the liquid dressing prepared by the technical scheme of the invention is safe and non-irritant, can protect skin wounds from being invaded by external pollutants and bacteria, and has the effects of moisturizing and repairing wound skin at the same time.

The invention relates to an adjustable skin tension measuring device. The adjustable skin tension measuring device comprises two fixed legs which are used for being fixed on skin on two sides of a wound and are connected through a connecting rod, a propelling component is connected to the fixed legs and is used for pushing the two fixed legs to slide on the connecting rod, a locking structure is arranged at one end of the propelling component, a spring is arranged at the other end of the propelling component, a pressure sensor is arranged at a tail end of the spring, and a display (7) is connected to the pressure sensor. The adjustable skin tension measuring device can be used for measuring skin tensions of the wounds at different positions, can be used in vitro, has little possibility ofinjuring the skin and is easy in operation and convenient for disinfection and suitable for clinical application.

The invention discloses lactobacillus rhamnosus FLRH93. The lactobacillus rhamnosus FLRH93 is preserved in the Guangdong Microbial Culture Collection Center, and has a preservation number of GDMCC No:60956. Animal damage intervention experiment results show that the lactobacillus rhamnosus FLRH93 can obviously improve the intestinal injury caused by drugs; tissue staining sections show that the strain maintains the integrity of a small intestine structure, reduces the loss of goblet cells after drug treatment, and can regulate and control the secretion of Bcl-2 and NLRP3, thereby reducing generation of inflammatory factors IL1-beta and TNF-alpha. The invention belongs to the technical field of microorganisms. The strain provided by the invention can improve the survival rate of mice withdrug injury and can also remarkably promote healing of wound skin.

The invention discloses an intelligent skin stretching device, and belongs to the technical field of medical instruments. The intelligent skin stretching device is composed of two hook elements and anelectric device which is controlled by an intellectualized program. Two specific embodiments are disclosed. The intelligent skin stretching device has the advantages that the intelligent skin stretching device is provided with the electric device which is controlled by the intellectualized program, thus traditional manual operation is replaced, and automatic stretching of skin on two sides of wounds and precise control are achieved, so that an operation effect which is more efficient, safer and better is obtained. The skin stretching device can turn large-spacing high-tension wounds (cuts) into small-spacing low-tension wounds (cuts), direct suturing is achieved, and the purpose of primary closure is achieved.

The present invention relates to a Chinese medicine prescription of compound centipede poultice which is used to externally remedy the cicatrical tissue proliferation of wounded skin. The Chinese medicine prescription uses 1 to 10 centipedes, 30 to 90g of nutgall, 10 to 30g of rhubarb, 10 to 30g of safflower and 10 to 30g of liquorice. The material is doubled when large dosage is needed. Dried and crushed to powder, the five Chinese medicines pass 100 mesh sieve and then is mixed and sealed for reserve. After cleaning, sterilizing and drying the wounded skin, the compound centipede powder is made into paste with 75 percent of alcohol in an abacterial porcelain jar. The user can use an abacterial cotton bud to dip the compound centipede powder and smear on the surface of the wounded skin evenly about 4 to 5 mm with a range larger than the wounded skin. Abacterial PE preservative film covers the paste surface. The wounded skin is covered and bound up according to different wounded part. The medicine should be changed for once to twice every day and for 1 to 3 weeks according to different wound situations. During the treatment time, the user should observe the curative effect.

The invention provides a fixing and suturing method for preventing wound skin shrinkage of rodents and an application of the fixing and suturing method. The method comprises the following steps of annularly cutting off dartos of which the width is 2-3mm along the wound margins of the wound skin of the rodents, enabling the outer diamter of a steel ring to coincide with the edge of the cut-off dartos, and fixing the stell ring, the skin, the dartos and subcutaneous tissue in a suturing manner by a continuous hemstitch suturing method. The fixing and suturing method is notable in shrinkage preventing effects, can reduce the shrinkage of wound surfaces of rats to the maximum extent without influencing epithelium creepage, and does not influence the healing quality of the wound surfaces. A shrinkage preventing model prepared by the method can effectively simulate a wound healing mechanism, can accurately assess the crust creepage process of the wound healing process, can well observe the derma remodeling process, can be used as a good model for researching the wound healing, and can be used as a platform for assessing various factors influencing wound healing. The method has high application value in the respect of scientific research.

The invention provides a flexible skin distraction closer. The flexible skin distraction closer comprises a fixing assembly and at least one drawing assembly; the fixing assembly comprises a pair of fixing plates and adhesive tape attached to release paper; the pair of fixing plates is arranged on two sides of injured skin; ends of the adhesive tape are attached to the surfaces of the fixing plates; Each drawing assembly comprises a clamping groove, a buckle and a pull strip; the clamping groove is fixedly connected to one of the pair of fixing plates; the buckle is fixedly connected to the other one of the pair of fixing plates; the pull strip is provided with a tooth groove; the pull strip penetrates through the clamping groove and the buckle; and the pull strip is movably matched with the buckle. The flexible skin distraction closer is used for distracting wound skin which is difficult to directly suture, can be bent and well attached to the skin by adopting the flexible pull strips and flexible connecting strips, and is suitable for various regular or irregular, flat or uneven wounds.

The invention discloses a rheumatism ointment capable of being adhered on the surface of wound skin. The rheumatism ointment comprises a base cloth and a medicine layer coated on the lower surface of the base block, and is characterized in that the base cloth is provided with a plurality of pores; each pore is covered by an individual paste; and the medicine layer is coated on the lower surface of the paste. The rheumatism ointment has greatest characteristics that the rheumatism ointment can be adhered on the surface of the skin with small wound, and the rheumatism ointment can timely relieve pain, and cannot injury the wound.

The invention relates to plant antibacterial cream. The plant antibacterial cream mainly comprises the following components of 3-10 parts of glycerine, 0.1-2 parts of xanthan gum, 0.1-1 part of potassium sorbate, 0.05-0.5 part of ethylenediamine tetraacetic acid disodium salt, 1-5 parts of ceteareth, 1-5 parts of 16/18 alcohol, 2-7 parts of glyceryl monostearate, 2-8 parts of white mineral oil, 1-4 parts of shea butter, 1-5 parts of silicone oil, 5-15 parts of traditional Chinese medicine powder, 0.5-2 parts of azone, 0.2-0.6 part of a preservative, 10-20 parts of deionized water and 50-70 parts of water, wherein the traditional Chinese medicine powder comprises 2-4 parts of a Chinese prickly ash extract, 1-5 parts of an argy wormwood leaf extract and 3-8 parts of a pomelo extract. According to the plant antibacterial cream, the traditional Chinese medicine powder is used as the additive, so that the plant antibacterial cream can achieve the effects of diminishing inflammation, stopping bleeding, dispelling wind and arresting itching on wound skin, can exert complete regulation advantages of a traditional Chinese medicine compound recipe, and is high in safety. Besides, in the cream, through cooperation of the azone and the xanthan gum, the merging of the traditional Chinese medicine powder, a liquid phase and an aqueous phase can be promoted, the permeation of the traditionalChinese medicine powder to the skin can be promoted, and the antibacterial effect can be improved.

The invention aims to provide an iodophor disinfection paste being prepared from potassium iodate, citric acid, fatty alcohol, borneol, mint, ethanol, glycerol, polyethylene glycol, polyalkyloxygen (40) stearate, povidone iodine and purified water. The iodophor disinfection paste is suitable for disinfecting ruptured skin wounds such as burning, scale, bedsores and the like or polluted and infected wounds, and skin trauma and sport trauma and the like wounds. The iodophor disinfection paste can quickly kill purulent bacteria causing wound infection and bacteria and microorganism generated due to festers, thereby preventing and controlling infection. The disinfection paste has excellent formula so that the disinfection paste can improve discomfortableness on wound skin, has the effects of alleviating pain, preventing decay, regenerating tissue and moisturizing skin, and being free of scab. The iodophor disinfection paste can control infection, can promote growth of granulation tissues, can reduce healing time of the wound and can improve healing rate of the wound.

The invention provides a crochet hook pull rod-type skin distraction closer. The crochet hook pull rod-type skin distraction closer comprises a pull rod, joints, a buckle and two groups of crochet hooks, wherein one side of the pull rod is provided with a tooth groove; a through hole is formed in the middle of each joint, and the pull rod penetrates through the through holes in the middles of the two joints; the buckle is fixedly arranged above the joint and is movably matched with the tooth groove in one side of the pull rod; and the two groups of crochet hooks are fixedly connected below the two joints respectively, and hook bending directions of the two groups of crochet hooks are opposite. The crochet hook pull rod-type skin distraction closer is used for distracting wound skin which is difficult to directly suture; wound skin distraction is performed by adopting the pull rod and the crochet hooks; a distraction force can be conveniently adjusted and can be reversibly adjusted; the crochet hook pull rod-type skin distraction closer can adapt to plane and non-plane irregular wounds, has a relatively small size, has small injury to skin, does not influence postoperative activities of a patient, and meanwhile, is very convenient to operate, and low in price.

The invention relates to a wound repairing strip comprising two adhesive tapes and at least two dragging lines or at least two added strengthening transverse lines, wherein the adhesive tapes are made of medical material and have certain space, the dragging lines are arranged between two adhesive tapes, and two ends of the dragging lines are respectively and integratedly connected with the adhesive tapes. The wound repairing strip has simple structure and convenient use, can drag skin on two sides of a wound to be matched after operation without hindering applying medicine and pasting gauzes and can ensure that the cut can naturally heal without suturing, thus avoiding stitching scars by stitching before, reducing scars because of extrusion deformation of a wound connecting part due to line dragging external force, and reducing the scar on the wound skin after operation, so that the invention can effectively improve beauty and naturality of the skin after operation. The product is suitable for human body crack because of falling down and mechanical breaking and also can be used for repairing the cut with different lengths and widths after surgical operation.

The invention discloses a preparation method of hEGF-rich lyophilized powder for repairing wound skin. The lyophilized powder is prepared by lyophilizing culturing supernatant liquid which contains anover-expression hEGF gene and is applied to production of stem cells; the cell concentration of the culturing supernatant liquid is more than or equal to 1x10<7>/ml; and the lyophilized powder contains the over-expression hEGF, human keratinocyte growth factors, human fibroblastic growth factors, human platelet-derived growth factors and fibronectin. The invention discloses the preparation methodof the hEGF-rich lyophilized powder for repairing the wound skin. The process is reasonable in design and is simple in operation; and the prepared lyophilized powder cannot only be applied to repairing treatment of wounds, including burns and scalds, long lasting healing of ulcer wound surfaces and the like, of patients; and the method is simple and feasible, is applied to large-scale productionof the culturing supernatant lyophilized powder for different sources of stem cells, and provides a new way for application of the stem cells to medical transformation career; and therefore, the method is higher in practicability.

The invention relates to a skin wound treatment instrument. The skin wound treatment instrument comprises a column-shaped casing, wherein an upper end of the casing is provided with a treatment head contact with skin, a groove is molded on an upper end surface of the treatment head, a chamber is molded at a lower side of the groove, a groove wall of the groove is provided with multiple through holes communicated with the chamber, air in the groove is pumped through the through holes to make a groove edge absorbed on the skin, the groove wall is provided with multiple nozzles capable of spraying medicine liquid onto the skin, the groove edge is provided with a negative electrode sheet connected with a negative electrode of a bioelectric field generator, and the middle portion of the groove is provided with a telescoping positive electrode sheet connected with a positive electrode of the bioelectric field generator. The skin wound treatment instrument is advantaged in that the treatment head can be absorbed on the wound skin, a bioelectric field can be generated at the wound skin after the positive and negative electrode sheets are electrified, and the bioelectric field has the functions of tissue cell division and multiplication facilitating and orientation migration to a wound center.