17 results about "Wound skin" patented technology

The utility model designs a high-molecular blood circulation blocking prevention elastic bandage, which comprises a high-molecular elastic bandage and is characterized in that a plurality of elastic sheets are arranged on the front surface of the high-molecular elastic bandage. And a plurality of elastic sheets are arranged on the back surface of the macromolecular elastic bandage. And the elastic sheet is square or circular. The elastic sheet is made of a foam material, and the foam material is polyurethane foam. The high-molecular elastic bandage has the advantages that after a bound wound swells, due to the fact that the high-molecular elastic bandage is covered with the foam materials, a buffer area exists between the bandage and the skin of the wound, and the interval areas between the foam materials can relieve compression on the skin and reduce the influence on blood supply.

This utility model relates to the field of negative pressure drainage technology, specifically a portable negative pressure drainage device, comprising a negative pressure source instrument, a dressing, and a drainage component. The negative pressure source instrument and the dressing are connected and cooperate through the drainage component to form a negative pressure environment to absorb fluid flowing from the patient's skin. The dressing includes a sponge layer, a baffle, and an adhesive layer. The adhesive layer adheres to the patient's skin, and the baffle corresponds to the wound area of ​​the patient's skin. The side of the baffle facing the patient's skin is used to place wet dressing medication, and the side of the baffle away from the patient is connected to the sponge layer. A gap exists between the side of the baffle facing the patient's skin and the patient's skin. The baffle is provided with ventilation holes to connect the gap between the sponge layer, the baffle, and the patient's skin. The sponge layer is used to absorb bodily fluids flowing from the patient's skin. This utility model utilizes the gap between the baffle and the patient's skin to reduce tearing of the patient's wound skin when changing or removing the dressing, thereby reducing the patient's pain.

The invention discloses an antibacterial hydrogel dressing taking spunlace non-woven fabric as a carrier and a preparation method of the antibacterial hydrogel dressing, and relates to the technical field of biomedical polymers. The antibacterial hydrogel dressing is composed of a spunlace non-woven fabric carrier layer and an antibacterial hydrogel functional layer loaded on the surface and in pores of the spunlace non-woven fabric carrier layer, and the preparation method comprises the following steps: sterilizing spunlace non-woven fabric to obtain a spunlace non-woven fabric carrier; adding the antibacterial component into the aqueous solution of the hydrophilic polymer base material to form a hydrogel precursor solution; and immersing the spunlace non-woven fabric carrier into the hydrogel precursor solution, and curing to obtain the antibacterial hydrogel dressing. The antibacterial hydrogel dressing prepared by the preparation method disclosed by the invention has the flexible breathable characteristic of spunlace non-woven fabric and the high swelling and antibacterial functions of hydrogel, has an excellent bactericidal effect on escherichia coli and staphylococcus aureus, can effectively promote healing of infected wounds, is suitable for clinical nursing of burn and traumatic skin injuries, and has wide application prospects. Wide clinical application prospects are realized.

The invention relates to the field of medical equipment, in particular to a plasma permeation enhanced DBD wound treatment patch device which comprises a power supply host and a high-voltage electrode patch, the power supply host comprises a dual-mode modulation module and a power supply high-voltage output end, and the power supply host outputs low-frequency high-voltage pulses and high-frequency low-voltage pulses at intervals under modulation of the dual-mode modulation module; the high-voltage electrode patch is connected with a power supply high-voltage output end and receives low-frequency high-voltage pulses and high-frequency low-voltage pulses output by the power supply high-voltage output end at intervals, the high-voltage electrode patch receives the low-frequency high-voltage pulses to excite and generate discharge plasma, and the high-voltage electrode patch receives the high-frequency low-voltage pulses to form reversible electroporation field intensity. Pulse power output of two functional modes is achieved through the dual-mode modulation module, more stable and safer plasma generation is achieved, the reversible electroporation effect on the wound skin surface is enhanced through high-frequency low-voltage pulses, the permeability of plasma active ingredients is enhanced, and therefore the more efficient wound treatment effect is achieved.

This application provides a high-voltage electrochemical composite hydrogel for wound skin repair and its preparation method. The high-voltage electrochemical composite hydrogel is prepared by using hydroxyethyl cellulose and acrylamide monomers as raw materials to form an interpenetrating network structure. Polyvinylidene fluoride (PVDF) and ZnO nanowires are used as piezoelectric materials, and are formed by interweaving PVDF and ZnO nanowires within the hydrogel. This high-voltage electrochemical composite hydrogel significantly improves the crystallization orientation and polarization efficiency of PVDF through mechanical stretching and polarization, resulting in an order-of-magnitude improvement in the piezoelectric properties of the composite hydrogel. Simultaneously, it retains the excellent flexibility and biocompatibility of the hydrogel, showing broad application prospects in flexible sensors, self-powered devices, and human-computer interfaces.

The invention relates to the technical field of medical auxiliary appliances, in particular to an intelligent wound classification and treatment auxiliary device applying an image recognition chip, which comprises a scanning bed, a base is arranged on one side of the scanning bed, a universal bracket is rotatably connected to the base, a rectangular frame is rotatably connected to the universal bracket, and a plurality of image recognition chips are arranged on the rectangular frame. A wound diagnosis and measurement assembly is arranged on the rectangular frame, a wound scanning assembly is arranged on the wound diagnosis and measurement assembly, the wound scanning assembly is arranged on the rectangular frame, the wound scanning assembly is driven by the wound diagnosis and measurement assembly to move freely, and during measurement, the universal support is adjusted to enable the frame to be parallel to wound skin; the laser transmitter is started, the light spot is aligned with one end of the wound, the imaging assembly moves along the wound, the computer records the moving distance in real time, the actual arc length of the curved suture wound can be accurately obtained, the defect that only the straight chord length can be measured through a traditional ruler shooting method is overcome, and the measurement precision of the curved wound length is remarkably improved.

Disclosed herein are therapeutics compositions including one or more active agents, for instance a statin, cyclodextrin, or combination thereof. The compositions are useful in the treatment of tissue injuries, including wounds, as well as skin inflammation and infections.

The invention discloses application of water microspheres of modified polysaccharide in promoting wound skin regeneration and inhibiting wound skin fibrosis. In the invention, compared with a Control group (silicone oil) as a control and an unmodified polysaccharide water microsphere group (AVBEC), when the modified polysaccharide water microsphere group (AVBER) is externally applied to the skin of a bama miniature pig in a deep II-level scald model, the wound healing can be effectively promoted, the inflammation degree and duration can be controlled, and the extracellular matrix composition and plasticity can be regulated; expression of fibrosis marker protein is reduced, and the dual effects of promoting skin regeneration and inhibiting fibrosis are achieved. The problems that natural extracts and common polysaccharide microsphere products are low in biological activity and poor in stability are solved, and new functions of modified polysaccharide are found.

The invention belongs to the technical field of biological medicines, and particularly relates to a recombinant collagen repair liquid as well as a preparation method and application thereof. Comprising the following steps: preparing a protein activity enhancer; preparing a recombinant humanized collagen fiber sol; and carrying out photopolymerization to construct the recombinant humanized collagen hydrogel. After turnip pollen polysaccharide is subjected to sulfating modification and compounded with recombinant humanized collagen, the turnip pollen polysaccharide and positively charged collagen amino acid residues can form a stable compound through electrostatic interaction, natural triple helix conformation of the turnip pollen polysaccharide is maintained, collagen aggregation denaturation is reduced, and the activity of the turnip pollen polysaccharide is enhanced; in addition, the recombinant humanized collagen can be assisted in activating cell surface receptors and enhancing adhesion and proliferation of cells, so that the epidermal regeneration promoting capacity of the recombinant humanized collagen is enhanced, and the bioavailability of the recombinant humanized collagen at wounds and the repair treatment effect of the recombinant humanized collagen on the wounded skin can be effectively improved.

Provided herein are secretory compositions / cocktails derived from a novel, extremophilic fungal species cultured, isolated, and characterized herein. Said novel, extremophilic fungal species may be exploited to produce secretory compositions / cocktails which comprise a unique mixture of thermo-tolerant, stable enzymes capable of digesting cellular and genetic material in its surroundings under extreme temperatures. Such secretory compositions / cocktails may be useful as cleaning and sterilization solutions against biofilm, urine, yeast, bacterial, or viral contamination. Other uses include, but are not limited to, urea removal, fertilizer wastewaters, wastewater reclamation for life support systems in space, pH control, source of ammonia and carbon dioxide, starch digestion, biofuel production, as pharmaceuticals, and medical treatments such as wounds, skin disorders, or nail disorders.

The invention relates to the technical field of medical instruments, and particularly discloses a gel smearing device for wound skin repair, which comprises a holding block and a smearing mechanism, the smearing mechanism comprises a medicine cylinder and smearing assemblies symmetrically arranged in the width direction of the medicine cylinder. The medicine cylinder is fixedly connected with the holding block; the smearing assembly comprises a side shaft, a side block, a hollow disc, smearing cotton, a hollow cylinder, a medicine discharging box, a medicine discharging pipe, a piston cylinder, a piston block, a medicine discharging hole formed in the medicine discharging box, a driving part used for driving the side shaft to rotate, and a power part used for driving the piston block to do vertical reciprocating motion. The side shaft is rotationally connected with the pesticide barrel; two ends of the side block are fixedly connected with the side shaft and the hollow disc respectively; the coating cotton is detachably connected with the hollow disc; two ends of the hollow cylinder are fixedly connected with the pesticide cylinder and the lower pesticide box respectively; two ends of the medicine feeding pipe are respectively communicated with the medicine cylinder and the medicine feeding box; the piston cylinder is fixedly connected with the lower pesticide box; the piston block is slidably connected with the piston cylinder. The problem that an existing medicine applying device cannot evenly apply medicine to an affected part is solved.

The invention provides a boa oil-containing composition for laser postoperative skin repair, a biological preparation and a preparation method of the biological preparation, and relates to the technical field of biological medicines. The boa oil-containing composition for laser postoperative skin repair comprises the following components in parts by weight: 10-20 parts of a boa oil compound, 10-20 parts of a traditional Chinese medicine composition and 1-5 parts of senna angustifolia seed polysaccharide, the traditional Chinese medicine composition comprises ganoderma lucidum, uncaria, dicliptera chinensis, glossogyne tenuifolia, ginseng, pseudo-ginseng, polygonatum odoratum and dragon's blood. The composition is specifically combined to form a synergistic repair system, provides comprehensive repair for the skin after the laser surgery, can repair the wound surface, rapidly penetrate through the skin, is high in healing rate, enables the skin to rapidly fade red and not to be allergic, and also can supplement skin cuticle moisture, lock moisture, relieve skin dryness and prevent the outside from irritating the wound surface skin.

The present application relates to the technical field of medical information processing, in particular to a kind of free flap grafting wound injury ultrasound evaluation method, comprising: the ultrasound gray scale image obtained is carried out block processing to obtain each enhanced analysis candidate block, block processing helps to improve the contrast of fat area and edema area;By fat feature screening parameter screening obtains several enhanced analysis target blocks, to a certain extent reduce image data analysis amount, improve the efficiency of wound injury ultrasound evaluation;Blood vessel ultrasound frequency shift characteristic value and fat echo factor are combined to determine the fat feature first evaluation value of enhanced analysis target block, and then determine the fat feature second evaluation value of each gray level, which helps to realize the enhancement of fat area differentiation under the condition that probe and wound skin contact is not good, and obtain enhanced ultrasound gray scale image for wound injury ultrasound evaluation with better enhancement effect.

The invention relates to the technical field of medical instruments, in particular to a thoracic surgery postoperative drainage tube fixing structure. Comprising a fixed paste fixedly connected with a fixed shell, a first movable shell slidably connected to the fixed shell, and a second movable shell slidably connected to the fixed shell. The mounting shell is fixedly connected to the first moving shell; the number of the first moving frames and the number of the second moving frames are both multiple, the first moving frames are fixedly connected to the fixing paste, the second moving frames are fixedly connected to the first moving shell, and the first moving frames are in sliding connection with the corresponding second moving frames; buffering blocks are fixedly connected between the first moving frame and the first moving shell and between the second moving frame and the fixing paste. Pressure acting on the drainage tube is converted into gentle displacement through the buffer block, and compression and pain on wound skin of a patient are relieved; meanwhile, the installation shell directly protects the pipeline from being pressed and folded, integral buffering is combined to ensure smooth drainage, and clinical risks caused by pipeline blockage are prevented.

The invention provides application of nintedanib in prevention and treatment of wound proliferative fibrosis diseases, the nintedanib or pharmaceutically acceptable salt thereof is prepared into a medicament by adding auxiliary materials, acts on wounds of subjects in manners of smearing, spraying, application, oral administration, injection and the like, can inhibit neovascularization, reduce fibroblast growth and reduce inflammation, and can be used for preventing and treating the wound proliferative fibrosis diseases. The wound skin can be recovered as far as possible. According to the invention, nintedanib is adopted to carry out external local treatment during wound stitch removal, so that the growth of new vessels is inhibited in the early stage, the number of fibroblasts is reduced, the wound skin is recovered to be normal as far as possible, a treatment window is advanced to the abnormal stage of the new vessels, and wound fibrosis and scar formation are avoided. The treatment is greatly simplified, the treatment pain of a patient is reduced, and the treatment cost is also greatly reduced.

The breast postoperative upper limb exercise wound anti-cracking device has the advantages that the fixed seat is fixed on the skin of the patient and the first pressing rod is located above the wound, two groups of second pressing rods are located on the two sides of the wound, the first pressing rod and the second pressing rods are in contact with the skin of the patient, when the patient lifts the arm and the driving part slides upward, the driving part slides upward and drives the first pressing rod and the two groups of second pressing rods to fold towards the wound through the transmission mechanism, the first pressing rod and the two groups of second pressing rods fold towards the wound and drive the skin around the wound to move towards the wound, so that the skin of the patient around the wound is prevented from being pulled and cracked in the process of lifting the arm, and the upper limb exercise is convenient.

The invention provides a collagen dressing for promoting wound healing and a preparation method thereof. The dressing is prepared from the following raw materials in parts by weight: 20 to 26 parts of collagen peptide, 17 to 21 parts of mussel extract, 6 to 9 parts of keratin, 6 to 9 parts of sodium alginate, 4 to 7 parts of peptidoglycan, 1 to 3 parts of polypeptide, 18 to 23 parts of polysaccharide, 16 to 20 parts of compound plant extract, 8 to 13 parts of sodium hyaluronate, 7 to 11 parts of gelatin, 8 to 12 parts of carbomer, 7 to 10 parts of glycerinum, 0.002 to 0.004 part of preservative and 66 to 80 parts of water. The collagen peptide, the mussel extract, the keratin, the peptidoglycan, the polypeptide, the polysaccharide, the composite plant extract, the sodium hyaluronate and other raw materials are reasonably matched and used, so that a protective layer can be formed on a wound surface, exudate of the wound is effectively absorbed, good anti-inflammatory and antibacterial effects can be achieved, invasion of external harmful germs can be effectively resisted, and the wound healing effect is good. The cell activity can also be improved, wound skin cell regeneration is promoted, wound healing is helped, and the wound healing time is effectively shortened.