2 results about "Massive bleeding" patented technology

This invention discloses a pressure-adjustable extravascular occlusion balloon with drainage and flushing function, relating to the field of vascular hemostasis technology. It includes a tubing wall with a C-shaped front end. Several balloons that can compress each other are arranged inside the C-shaped tube. A balloon catheter is inserted through the tubing wall, with one end connected to the balloon and the other end extending out from the rear end of the tubing wall. This invention can quickly control massive bleeding, achieving hemostasis without causing permanent loss of blood supply to the controlled blood vessel, thus avoiding related complications caused by ischemia.

The invention relates to a composite sponge based on calcium silicate biological ceramic and a preparation method and application thereof, St-Nor and HS-PEG-SH are prepared into a polymer precursor solution, a proper amount of modified anion polysaccharide-sodium alginate is introduced, then the prepared CS is added into the polymer solution, and after foaming treatment, cross-linking curing and freeze drying, the composite sponge based on calcium silicate biological ceramic is obtained. A series of composite sponges based on calcium silicate biological ceramics are obtained, the composite sponges not only have good water absorption capacity and rapid shape recovery capacity, but also have relatively strong mechanical properties, have the potential of expandable hemostatic sponges in incompressible and massive hemorrhage applications, have relatively strong water absorption capacity and macroporous structures, and are suitable for large-scale popularization and application. When the sponge is in contact with blood, blood components such as blood platelets and red blood cells can be effectively enriched, and meanwhile, CS in the sponge plays an important role in accelerating the blood coagulation process. The negative charges in the sponge activate the blood coagulation factor XII and thrombin to trigger the blood coagulation cascade rapid reaction, and further enhance the thrombus strength through the interaction with fibrinogen, so that the sponge has an enhanced hemostatic effect in a massive hemorrhage model and a massive hemorrhage model in a blood dilution state.