The invention provides a novel medical degradable hemostatic material and a preparation method thereof. According to the preparation method, a dry-heat crosslinking method is adopted to crosslink
chitosan and a derivative thereof, and
starch and a derivative thereof, a crosslinked sample is made into a
microsphere by a method of electrostatic droplet, in the process of preparing the
microsphere, asoluble
calcium salt solution is used as stationary liquid,
calcium ions are complexed on the
microsphere, then physical pore-forming is conducted on the microsphere through a method of
ultrasound, aporous microsphere sample is dried through supercritical and sprayed mode, the
polysaccharide composite hemostatic material prepared by adopting the preparation method has the advantages of both thestarch and the
chitosan, the hemostatic ability is high,
antibacterial activity is achieved,
toxicity and stimulation are avoided, the process is simple,
reagent residue is avoided,
pollution is avoided, the cost is low, using is convenient, the
polysaccharide composite hemostatic material is suitable for fast
hemostasis of
massive bleeding, irregular parts and viscera, and also can be used as a
raw material of anti-adhesion products,
hemostasis products and dressing products.