44 results about "Abdominal aorta" patented technology

The balloon catheter blood pump comprises a pump body, a flow guide cone, a tail sleeve, a five-cavity catheter, a balloon and an impeller rotor assembly, the pump body comprises an inflow cage, a middle section and an outflow cage, the outflow cage end of the pump body is connected with the flow guide cone, the flow guide cone is connected with the tail sleeve, the tail sleeve is connected with the five-cavity catheter, and the five-cavity catheter is connected with the impeller rotor assembly. The two ends of the balloon are fixed to the middle section of the pump body in a sleeved mode, five round holes are formed in the cross section of the five-cavity catheter and include two flushing fluid perfusion holes, a wiring hole, a balloon injection hole and a center hole, the impeller rotor assembly comprises an impeller, an impeller shaft, a bearing and a flexible transmission shaft, and the impeller is installed at the far end of the impeller shaft and arranged in the pump body. A bearing is arranged between the impeller shaft and the inner wall of the flow guide cone, the near end of the impeller shaft is connected with the far end of a flexible transmission shaft, the flexible transmission shaft penetrates through the center hole, a gap a is reserved between the impeller shaft and the flow guide cone in the radial direction, and a gap b communicated with the gap a is reserved between the impeller and the flow guide cone in the axial direction.

Some embodiments of a rotational atherectomy device can remove (partially or completely) stenotic lesions in blood vessels by rotating one or more abrasive elements in an orbital path to abrade and breakdown the lesion. In particular implementations, multiple abrasive elements are arranged along a distal portion of a drive shaft with an improved configuration so as to facilitate both efficient navigation into vessels extending from the abdominal aorta such as the common iliac artery, the external iliac artery, the internal iliac artery, the profunda artery, the gluteal artery, and the pudental artery and effective orbital paths for abrading stenotic material in such vessels and junctions between such vessels.

The retractor for thoracoabdominal aorta replacement comprises a clamping assembly connected with an operating bed, the upper half portion of the clamping assembly is connected with a first connecting rod through a first locking assembly, the other end of the connecting rod is connected with two symmetrically-arranged universal balls through a second locking assembly, the universal balls are connected with a second connecting rod, and the second connecting rod is connected with a second connecting rod. A plurality of first traction assemblies and a plurality of second traction assemblies are installed on the second connecting rod through third locking assemblies. The device can be installed at any position of an operating bed, the second connecting rod can rotate by 360 degrees through the universal ball, the device adapts to patients with different fatnesses, the mounting angle and the mounting position can be adjusted through various locking assemblies, the device further adapts to patients with different body types, the whole structure can be detached into single structures to be disinfected and maintained, and the device is very convenient to use.

The invention relates to the technical field of medical instruments, and discloses a disposable simple in-vitro transplantation renal artery perfusion apparatus which comprises a buckle seat, a panel and a perfusion tube, a perfusion tube mounting hole is formed in the middle of the panel, the perfusion tube is connected in the perfusion tube mounting hole in the middle of the panel in a penetrating mode, one end of the perfusion tube is connected with a perfusion tube, and the other end of the perfusion tube is connected with a drainage tube. The other end is inserted into the abdominal aorta; the buckle base comprises a bottom plate and side plates arranged at the two ends of the two sides of the bottom plate, a penetrating hole is formed in the middle of the bottom plate, and clamping grooves are formed in the inner sides of the side plates. The disposable simple in-vitro transplantation renal artery perfusion apparatus can be effectively fixed at an opening of an artery, perfusion can be carried out by connecting an infusion tube, assistance of other people is not needed, fixation is good, perfusate cannot leak out to cause waste, and intima of the artery cannot be damaged to cause series complications.

Some embodiments of a rotational atherectomy device can remove (partially or completely) stenotic lesions in blood vessels by rotating one or more abrasive elements in an orbital path to abrade and breakdown the lesion. In particular implementations, multiple abrasive elements are arranged along a distal portion of a drive shaft with an improved configuration so as to facilitate both efficient navigation into vessels extending from the abdominal aorta such as the common iliac artery, the external iliac artery, the internal iliac artery, the profunda artery, the gluteal artery, and the pudental artery and effective orbital paths for abrading stenotic material in such vessels and junctions between such vessels.

The present invention relates to a self-expanding stent (1) for implantation in the abdominal aorta of a human body for the treatment of abdominal aortic aneurysm, the stent (1) comprising an expandable framework (2) formed from a shape memory alloy and having a distal end (4), a proximal end (6), and an interior volume extending along a central axis from the distal end (4) to the proximal end (6), the framework (2) having at least a distal end ring (8) and a proximal end ring (10) with peaks (12) and valleys (13), and optionally at least one ring (14, 15) disposed between the distal end ring (8) and the proximal end ring (10), the framework (2) having a length LF from the distal end (4) to the proximal end (6) of at least 10 mm, the stent having a compressed state having a minimum diameter (Dmin), an expanded state having a nominal diameter (DN), and a relaxed state having a maximum diameter (Dmax). According to the present invention, at least one of the distal ring (8), the proximal ring (10), and the optional rings (14, 15) of the stent (1) exhibits a nominal radial resistance pressure (RRP-N) of 100 mmHg or greater at a nominal diameter (DN). The present invention also relates to a method.

Described herein are pumps that linearly reciprocate to assist with circulating blood within the body of a patient. Red blood cell damage may be avoided or minimized by such linear pump movement. The linearly reciprocating movement may also generate a pulsatile pumping cycle that mimics the natural pumping cycle of the heart. The pumps may be configured to reside at various body locations. For example, the pumps may be situated within the right ventricle, the left ventricle, the ascending aorta, the descending aorta, the thoracic aorta, or the abdominal aorta. In some instances, the pump may be deployed within the venous circulation. In other instances, the pump may reside outside the patient.

The utility model discloses a multifunctional bedside nasojejunum nutrition tube placement training device which comprises a head and neck bionic block, a nasopharyngeal cavity channel is arranged in the head and neck bionic block; the pleuroperitoneal cavity frame comprises a hard simulation frame and bionic skin covering the hard simulation frame. Wherein the head and neck bionic block and the pleuroperitoneal cavity frame are integrally formed or detachably connected. A bionic esophagus, a bionic stomach, a bionic duodenum and a part of bionic jejunum which are sequentially connected are arranged in the pleuroperitoneal cavity frame, and a bionic cardia and a bionic pylorus are arranged at the head end and the tail end of the bionic stomach respectively. A bionic inferior vena cava, a bionic abdominal aorta, a bionic mesenteric superior vein and a bionic mesenteric superior artery are further arranged in the pleuroperitoneal cavity frame; the bionic inferior vena cava and the bionic abdominal aorta are arranged on the rear sides of the bionic stomach and the bionic duodenum, the bottom ends are closed, and the head ends penetrate out of the bionic skin; the bottom ends of the bionic superior mesenteric vein and the bionic superior mesenteric artery are closed, and the head ends of the bionic superior mesenteric vein and the bionic superior mesenteric artery partially wrap the bionic duodenum and then penetrate out of the bionic skin.

The application discloses an ultrasonic imaging system for accurately collecting heart sections in any body position, which comprises a plurality of two-dimensional ultrasonic arrays randomly distributed in space, a multichannel ultrasonic signal collecting module and a three-dimensional ultrasonic imaging module; the plurality of two-dimensional ultrasonic arrays, the multichannel ultrasonic signal collecting module and the three-dimensional ultrasonic imaging module are sequentially connected; wherein the plurality of two-dimensional ultrasonic arrays comprises a plurality of ultrasonic transducer arrays forming sub-area line scanning or sub-area surface scanning or cross surface scanning; the application provides doctors with more detailed images, which is helpful for more accurately positioning and evaluating lesions; can solve the problems of difficulty in collecting correct imaging sections, imaging section changes in motion and the like in wearable ultrasonic heart imaging; is not only suitable for the heart, but also suitable for the brain, the liver, the kidney, the urinary bladder, the abdominal aorta, the inferior vena cava and the like human tissues and parts.

The invention provides an ultrasound imaging enhanced balloon, a preparation method thereof and an ultrasound imaging enhanced abdominal aorta blocking device. The ultrasonic imaging enhanced balloon comprises a balloon body and an ultrasonic imaging enhanced coating, and the outer surface of the balloon body is coated with the ultrasonic imaging enhanced coating; wherein the ultrasonic imaging enhanced coating comprises ultrasonic imaging enhanced particles, a silica gel polymer and a curing agent; the ultrasonic imaging enhanced particles comprise at least one of metal nanoparticles, metal oxide nanoparticles, gas encapsulated microbubbles or liquid encapsulated microbubbles, and the average particle size of the ultrasonic imaging enhanced particles is 40-150 nm. According to the balloon, real-time and clear positioning and state recognition can be achieved, the intraoperative balloon positioning precision is remarkably improved, dependence on the experience of an operator is reduced, and the occurrence rate of complications such as puncture injury and intraoperative bleeding caused by inaccurate positioning is also effectively reduced.

The invention provides a preparation method of a soft tissue filling agent with a vascularization promoting function, and relates to the field of medical biological materials, and the preparation method comprises the following steps: taking aorta abdominalis blood vessels, carrying out alkali treatment, rinsing, decellularizing, disinfecting, carrying out secondary rinsing, shearing, grinding, sieving, and compounding with cross-linked sodium hyaluronate gel to obtain soft tissue filling gel. The soft tissue filling agent prepared by the method contains rich elastin and factors for promoting vascularization, and can improve the defects of the existing materials in tissue filling and repairing.

The balloon catheter blood pump comprises a pump body, a flow guide cone, a tail sleeve, a five-cavity catheter, a balloon and an impeller rotor assembly, the pump body comprises an inflow cage, a middle section and an outflow cage, the outflow cage end of the pump body is connected with the flow guide cone, the flow guide cone is connected with the tail sleeve, the tail sleeve is connected with the five-cavity catheter, and the five-cavity catheter is connected with the impeller rotor assembly. The two ends of the balloon are fixed to the middle section of the pump body in a sleeved mode, five round holes are formed in the cross section of the five-cavity catheter and include two flushing fluid filling holes, a wiring hole, a balloon injection hole and a center hole, the impeller rotor assembly comprises an impeller, an impeller shaft, a bearing and a flexible transmission shaft, the impeller is installed at the far end of the impeller shaft and arranged in the pump body, and the bearing is arranged at the far end of the impeller shaft. A bearing is arranged between the impeller shaft and the inner wall of the flow guide cone, the near end of the impeller shaft is connected with the far end of a flexible transmission shaft, the flexible transmission shaft penetrates through the center hole, a gap a is reserved between the impeller shaft and the flow guide cone in the radial direction, and a gap b communicated with the gap a is reserved between the impeller and the flow guide cone in the axial direction.

This invention relates to a vascular stent for the visceral region of the abdominal aorta, comprising an interconnected proximal non-degradable segment and a distal degradable segment. The proximal non-degradable segment includes a non-degradable metal skeleton and a covering structure. The distal degradable segment is a degradable bare skeleton. The proximal non-degradable segment corresponds to the location of the primary tear in the visceral region of the abdominal aorta, and the distal degradable segment corresponds to the location of branch vessels in the visceral region of the abdominal aorta. This invention is applicable to abdominal aortic dissection anatomical features, where the proximal stent segment is non-degradable and covered, while the distal visceral segment is degradable but not covered. It promotes false lumen thrombosis by sealing the primary tear through covering, while maintaining patency of branch vessels in the visceral segment by not covering. Simultaneously, a drug layer is attached to the covering of the proximal stent segment to actively promote intimal repair.

This invention discloses an experimental rat abdominal aorta fixation and blood collection device, belonging to the field of animal fixation and blood collection technology. It includes an experimental body with an operating table mounted on its upper end. The operating table has a Velcro structure in the middle and an absorbent pad is attached. Four side plates are vertically fixed at the four corners of the experimental body, and supplementary lights are mounted on the opposite sides of each side plate. Four movable slots are formed near the four corners of the operating table, and four magnetic restraint devices are movably connected within these slots. A controller is fixed to the front end of the experimental body and electrically connected to an external power source. This invention provides that the four magnetic restraint devices can be adjusted according to the length of the rat's limbs, and the controller controls four electromagnets to attract two iron blocks on four elastic restraint straps, completing rapid restraint and fixation. The operation is relatively simple and convenient, improving the efficiency of blood collection.

The utility model provides a catheter used for expanding a severe stenosis renal artery opening, the catheter is an elastic catheter, two ends of the catheter are respectively an input port and an output port, the catheter comprises a straight section, a bending section and an attacking section which sequentially extend between the input port and the output port, and the straight section is provided with an opening. The end, away from the input port, of the straight section extends towards one side in the radial direction to form the bent section and the straight section, and the included angle between the axis of the attack section and the axis of the straight section is not larger than 90 degrees. According to the catheter for expanding the severe stenosis renal artery opening, based on the anatomical structure relation between the renal artery and the aorta abdominalis, the attack section located at the head end of the catheter and the telecentric end of the aorta abdominalis form a right angle or an acute angle, and the appearance and the elasticity modulus of the attack section are limited, so that tension and stress of the bent section can be smoothly transferred; and therefore, the needle can easily and smoothly pass through the narrow section of artery during rolling and impact.

Disclosed are an automatic scoring method and an automatic scoring system for abdominal aortic calcification to simulate the doctor's scoring process. The CNN is first used to locate and recognize the aorta from the first lumbar vertebra to the fourth lumbar vertebra and the aorta in the corresponding area, then an improved regression model is used to automatically perform the scoring task. With particular attention to the continuity of sample data, a regression model that can capture the continuity of the intrinsic ordered relationship between samples is designed to ensure that the changing trend of the calcification degree is reflected more accurately. A regression model is constructed based on the intrinsic continuity of samples, which solves the problem of ignoring data continuity in the direct regression method, making the scoring to be more reflective of the continuous changes in calcification severity.

The utility model discloses an aorta abdominalis covered stent and a stent system, and belongs to the technical field of aorta abdominalis covered stents. The utility model provides an aorta abdominalis covered stent which comprises a stent body, and a first through hole, a second through hole and a third through hole are formed in the stent body in the longitudinal direction of a cylinder. The middle section of the support body is provided with an open groove, the second through hole and the third through hole are broken through the open groove, and the first through hole is not broken through the open groove. Therefore, according to the aorta abdominalis covered stent, the aorta abdominalis stent can be communicated with the four branch arteries. The first through hole is not affected by the open groove and penetrates through the stent body, and therefore it can be guaranteed that blood in the aorta abdominalis is smooth all the time. The slotting does not need to be customized according to the condition of a patient, and professional batch production can be realized, so that the manufacturing efficiency and the use reliability are improved.

The vessel forceps comprise a first forceps handle and a second forceps handle, the upper side of the first forceps handle is provided with a rectangular groove, the inner side of the rectangular groove is rotatably connected with a rotating shaft, the rotating shaft is fixedly connected with the second forceps handle, and the rotating shaft is fixedly connected with the second forceps handle. Handle parts are fixedly connected to the outer sides of the first plier handle and the second plier handle, a first clamping block is fixedly connected to one side of the first plier handle, a second clamping block is fixedly connected to the side, close to the first clamping block, of the second plier handle, and a first plier head is fixedly connected to the right side of the first plier handle. According to the vessel forceps suitable for abdominal aorta blocking and catheterization, by arranging the first forceps handle, the second forceps handle, the mounting plate, the side blocks, the contact plates, the pulling plate, the first spring, the second spring, the clamping rod and the clamping hole, when the first forceps head and the second forceps head block a blood vessel, the multiple contact plates can conveniently and rapidly extrude a suction tube through movement of the pulling plate, the blood vessel blocking effect is improved, and operation is easy.

The invention provides a covered stent system for curing total aortic dissection, which comprises a main stent, a large crevasse plugging device and a non-clogging blood flow branch stent, the main stent is used for blocking the crevasse, the main stent comprises a main stent skeleton and a micropore covering film, the large crevasse plugging device is wrapped in the main stent, and the micropore covering film is arranged in the main stent skeleton. The microporous stent is used for supporting the structure of a lesion position with a large crevasse, and the microporous stent is used for enabling some small branch passages to be unblocked; however, if a large crevasse exists at a non-branch position, the micropore of the micropore stent still causes the expansion of the interlayer, and at the moment, a large crevasse plugging device needs to be used. According to the invention, full aorta continuous treatment is realized: the main stent is designed to cover the whole course of thoracico-abdominal aorta and can be connected with an implanted individualized thoracico-aorta stent system to form a complete treatment scheme of the full aorta.

The application discloses an abdominal aorta automatic segmentation method based on a segmentation sampling neural network, and specifically comprises the following steps: obtaining a historical CT sequence scanning image, performing image preprocessing and cutting with a preset size to obtain an original cutting file; inputting the original cutting file into a pre-trained front segmentation network model after down-sampling to perform forward propagation, and obtaining a full receptive field prediction file; performing global segmentation sampling on the original cutting file based on a segmentation step to obtain a plurality of first sub-domain files; performing local segmentation sampling on the original cutting file based on the segmentation step to obtain a plurality of second sub-domain files; constructing and training a sub-domain prediction network model, wherein the sub-domain prediction network model takes the full receptive field prediction file, all the first sub-domain files and all the second sub-domain files as inputs; and using the front segmentation network model and the trained sub-domain prediction network model to perform target segmentation on a real-time CT sequence scanning image to obtain a voxel segmentation model of the abdominal aorta.

Described herein are pumps that linearly reciprocate to assist with circulating blood within the body of a patient. Red blood cell damage may be avoided or minimized by such linear pump movement. The linearly reciprocating movement may also generate a pulsatile pumping cycle that mimics the natural pumping cycle of the heart. The pumps may be configured to reside at various body locations. For example, the pumps may be situated within the right ventricle, the left ventricle, the ascending aorta, the descending aorta, the thoracic aorta, or the abdominal aorta. In some instances, the pump may be deployed within the venous circulation. In other instances, the pump may reside outside the patient.

The invention relates to application of an Arteridin gene as a biomarker in preparation of a product for auxiliary diagnosis of abdominal aortic aneurysm, clinical specimens and animal experiments find that the expression of Arteridin in occurrence of abdominal aortic aneurysm is remarkably increased, which indicates that Arteridin can be used as the biomarker for auxiliary diagnosis of abdominal aortic aneurysm; the invention also relates to a product for down-regulating the expression of Arterin and an application of the product in preparation of drugs for treating abdominal aortic aneurysm, the product comprises siRNA and shRNA of a targeted Arterin gene and AAV for coding the sequence of the shRNA, and after specific knockdown of Arterin by smooth muscle cells is realized, in an Elatase-induced abdominal aortic mouse model, the expression of Arterin is reduced, and the expression of Arterin is reduced. The diameter of the aneurysm is reduced, the occurrence rate is reduced, the elastin destruction degree is reduced, the expression quantity of vascular remodeling genes MMP2 and MMP9 is reduced, and the difference is obvious compared with that of a control group; the result shows that Arteridin is expected to become a target spot for treating abdominal aortic aneurysm.

The present application relates to a kind of adjustable bending delivery system for delivering implant into human body, the adjustable bending delivery system includes conveyor and bending device, the conveyor includes delivery sheath tube, the bending device includes bending sheath tube, the bending sheath tube distal end can be bent to make the bending device distal end be bent, the delivery sheath tube distal end can be accessed into human body from the artery on one leg, the bending device distal end can be accessed into human body from the artery on another leg, when the delivery sheath tube and the bending device distal end are pushed to abdominal aorta, the delivery sheath tube and the bending device distal end can cooperate in abdominal aorta, so that the bending sheath tube can drive the delivery sheath tube to be bent after bending.The adjustable bending delivery system provided by the present application requires smaller bending force, higher bending sensitivity, more stable bending process, more accurate bending direction, and better overall bending effect.

Devices, systems, and methods for patient-specific, custom-designed fenestrated implants. Various examples involve abdominal aortic stent-grafts with custom-designed fenestration features for perfusion of the renal arteries, mesenteric arteries, and / or celiac trunk arteries.

The invention discloses a conveying device for implanting an intrusive axial flow blood pump into an aorta abdominalis. The conveying device comprises a sheath tube, a sheath base assembly and a bypass extension tube assembly. The sheath base assembly comprises an operating handle, a sealing gasket and a gland, the bypass extension tube assembly comprises a Luer taper and a drainage tube, the operating handle is provided with a through hole, a drainage hole communicated with the through hole is formed in one side of the operating handle, the drainage tube is installed in the drainage hole, the sheath tube is installed at the far end of the operating handle, and the gland is connected with the near end of the operating handle by pressing the sealing gasket. The gland is connected with the locking cap through threads, the locking cap is connected with the handle end of the axial flow blood pump through the sterile sleeve, the axial flow blood pump penetrates through the sheath base assembly, is arranged in the sheath tube and is connected and positioned through the gland, and then the axial flow blood pump and the conveying device are implanted into the body of a patient in a percutaneous mode. And the sterile sleeve is operated to slowly withdraw the conveying device, so that the elastic bracket of the axial flow blood pump is released.

The application discloses application of Danshen-Gegen vesicle-like nanoparticles and belongs to the technical field of biological medicine. The Danshen-Gegen vesicle-like nanoparticles (SPVLNs) are extracted and purified from Danshen-Gegen decoction liquid by using a differential super-high-speed centrifugation method. The SPVLNs have good blood compatibility. When the SPVLNs are applied to treating abdominal aortic aneurysm, the SPVLNs can obviously relieve thickening of a blood vessel wall, reduce infiltrative cells of an arterial media and an adventitia, improve reduction and fracture of elastic fibers of the blood vessel wall, increase stretchability of the elastic fibers of the blood vessel wall, reduce contents of tissue muscle fibers and collagen fibers, reduce a fibrosis degree of the collagen fibers, obviously improve pathological changes of a mouse abdominal aorta caused by Ang II, and are safe and non-toxic.

The invention provides application of an adeno-associated virus overexpressing CTH in preparation of drugs for extravascular treatment of abdominal aortic aneurysm. When the adeno-associated virus overexpressing CTH is applied to the periphery of abdominal aortic aneurysm, fracture of elastic fibers of abdominal aorta can be reduced, collagen deposition can be reduced, infiltration of macrophages (CD68) can be reduced, secretion of matrix metalloproteinase can be reduced, degradation of extracellular matrixes can be reduced, and occurrence and development of AAA can be relieved.

The application provides an abdominal aorta imaging method, which comprises the following steps: obtaining an ultrasonic echo signal of a target object abdominal space, reconstructing a three-dimensional ultrasonic image of the abdominal aorta based on the ultrasonic echo signal, selecting a target cross-section image from the three-dimensional ultrasonic image, and calculating related information of the abdominal aorta based on the target cross-section image. The three-dimensional ultrasonic image directly shows the overall structure information of the abdominal aorta, the provided abdominal aorta information is more abundant, the calculated related information of the abdominal aorta is more accurate, and therefore the accuracy of a disease diagnosis result based on the three-dimensional ultrasonic image is also higher. In addition, the application embodiment further provides an ultrasonic detection device to ensure the application and implementation of the above method in practice.

Methods, systems, and uses for determining abdominal aortic calcification involve determining abdominal aortic calcification from lateral lumbar images and diagnostic / prognostic uses for abdominal aortic calcification. The method for determining abdominal aortic calcification includes receiving lateral lumbar images and determining, using one or more processors, a score representative of abdominal aortic calcification from the images, the determining step including encoding the images to identify visual features and decoding the visual features to calculate a plurality of calcification scores, each for a segment of the abdominal aorta.

A method for the treatment of a patient for the purpose of lowering blood pressure and / or treating other medical conditions such as cardiac arrhythmias. A catheter having an ablation element is placed inside the body of a patient and is directed to a targeted location either on in the abdominal aorta where the right or left renal arteries branch from the aorta at or near the superior junction or ostia or on the inside of the inferior vena cava near the junction with the right renal vein or in the left renal vein at a position spatially near where the left renal artery branches from the abdominal aorta. Catheters designed for use in the method where these targeted locations are also disclosed and claimed.