36 results about "False lumen" patented technology

The methods and devices disclosed herein pertain to the percutaneous treatment of various forms of aortic dissection by at least partially filling the false lumen of the aortic dissection with a stabilization agent percutaneously and steps to decrease the size of the false lumen using the devices. Fluid maybe aspirated from the false lumen to decrease the volume of the false lumen. And the entrance opening between the true lumen and the false lumen may be sealed with a sealing agent such as a biocompatible adhesive. The medical devices disclosed herein generally comprise an extendable sealing element that is used in conjunction with a catheter to expand the true lumen while reducing the size of the false lumen. The device has the ability to aspirate and / or deliver fluid containing the stabilization agent into the false lumen.

An implantable medical device (30) for treating aortic dissections includes a stent graft part (34) having a bulbous section (48) of greater radial diameter than the radial diameter of first and second sections (60,62) of the stent graft part (34). The bulbous section (48) is able to close off the false lumen (10) of an aortic dissection, thereby to prevent any fluid backflow into the false lumen (10). Radiopaque markers (70) may be provided for orientation and deployment purposes. The device (30) is able to treat chronic dissections and reduce false lumen backflow, which remains otherwise an unresolved issue in the endovascular treatment of false lumen aneurysms.

The invention provides an aortic dissection aneurysm covered stent which comprises a cylindrical metal supporting portion and a cylindrical covered portion coated on the cylindrical metal supporting portion. A bulging covered portion is coated outside the cylindrical covered portion, and the middle portion of the bulging covered portion bulges outwards. By adopting the above structure, a false lumen crevasse can be sealed and isolated, space of a false lumen can be actively reduced, blood flow speed and blood flow in the false lumen can be changed, and the false lumen is ensured to quickly form thrombus within expected time; the outwards-bulging portion can effectively prevent displacement and sliding caused by blood flow impact after the stent is implanted in a human body, and disease relapse caused by exposure of an original aortic crevasse due to displacement of the stent is avoided.

The present invention discloses an aortic image analyzing method and system. The aortic image analyzing method comprises the following steps: step S1: acquiring CTA image data of the aorta; step S2: performing multiplanar reconstruction on the CTA image data; step S3: utilizing an artificial neural network model to identify the aortic lumen, the intima of the interlayer, the crevasse, and the branch vessel in the image obtained through multiplanar reconstruction; step S4: acquiring aortic dissection information according to the result of identification, wherein the aortic dissection information comprises the aortic diameter, the true lumen diameter, the false lumen diameter, the branch vessel angle, the location of the crevasse, and the extension status of the crevasse in the branch vessel. The aortic image analyzing method provided by the invention facilitates achievement of automation and rapidity of diagnosis and measurement of the aortic dissection, which not only can reduce the manual workload, but also can reduce the measurement error and avoid the influence of subjective factors.

The methods and devices disclosed herein pertain to the percutaneous treatment of various forms of aortic dissection by at least partially filling the false lumen of the aortic dissection with a stabilization agent percutaneously and steps to decrease the size of the false lumen using the devices. Fluid maybe aspirated from the false lumen to decrease the volume of the false lumen. And the entrance opening between the true lumen and the false lumen may be sealed with a sealing agent such as a biocompatible adhesive. The medical devices disclosed herein generally comprise an extendable sealing element that is used in conjunction with a catheter to expand the true lumen while reducing the size of the false lumen. The device has the ability to aspirate and / or deliver fluid containing the stabilization agent into the false lumen.

A medical device with anti-microbial properties to prevent infections. This medical device, such as an in-dwelling catheter, has a portion that is insertable into the body of a patient and accessible from outside the body once the portion is inserted. The portion has an outer wall, a first active lumen within the outer wall, and a false lumen within the outer wall in which the false lumen has a distal portion and a proximal portion. The false lumen contains an anti-microbial agent that provides the outer wall with anti-microbial properties. The distal portion of the false lumen is sealed. The false lumen may be adjacent to the first active lumen. The medical device may also contain a second active lumen, wherein the first active lumen is an inlet lumen and the second active lumen is an outlet lumen. Alternatively, the false lumen may surround the first active lumen.

The invention discloses a plugging device for far end tears of aortic dissection. The plugging device comprises a bare stent system and a plugging device body. A bare stent is accurately positioned and released by a bare stent releasing device, and the axial length can be limited and fixed by limiting rods; the plugging device body is composed of a big disc, a small disc and a short waist, the bigdisc and the small disc are in an arc shape from overlooking, a circle of bent hooks pointing to the circle center are arranged on the inner side of the small disc, the section of the short waist canbe in different shapes, and the contact surfaces of the short waist with the big disc and the small disc are sewn and wrapped by flexible blood impermeable materials. The plugging device is used forplugging the far end tears of the aortic dissection, can be matched with the tears of the dissection in shape, reduce internal hemorrhage and the risk of falling of the plugging device body, reduce hurt to inner walls of blood vessels by the big disc and the small disc, and adapt to the pathogenic structures of existing branched blood vessels nearby the tears, and reduces physical hurt to the inner wall of a false lumen by the big disc located in the false lumen.

The invention relates to the technical field of medical instruments, in particular to an endovascular repair graft for treating the aortic dissection false lumen. The endovascular repair graft is composed of an occluding part and a conveying device, wherein the body of the occluding part is of a cylinder structure formed by knitting wire mesh, and the body is covered with membranes, so that the occluding part forms a closed cavity. The endovascular repair graft can be stably fixed to the dissection false lumen and effectively occlude slits to cut off false lumen blood flow. Different from an existing occluder repair device which is placed in the aorta to precisely cover a slit, the occluding part is a closed stent graft and completely covers multiple or even all slits; meanwhile, as both ends, in the axial direction, of the occluding part are covered with the membranes, the occluding part is a closed cylinder, the shape and mechanical properties are strictly suitable for the false lumen, the occluding part can basically or even completely fill the false lumen, it is more difficult for blood to flow in or flow out, the false lumen blood flow is cut off, and thrombosis in the false lumen is accelerated.

A non-covered vascular scaffold comprises Z-shaped supports and grid supports which are integrally connected directly or connected alternately via one or any of medical macromolecular suture lines, metal rings and macromolecular vascular cloth. The non-covered vascular scaffold is of straight tube, expanded junction or converging structure and has good flexibility and good radial supporting force such that vascular true lumens are reshaped, false lumens are downsized and formation of thrombi in false lumens is promoted. The non-covered vascular scaffold employs a structure of the front end released later and can provide precision positioning; a control wire is passed through the trough of the tail end of the last grid support at the distal end of the vascular scaffold, the control wire is loosened to release the vascular scaffold, and the control wire is retracted to reclaim the vascular scaffold.

A device system and method for the treatment of aortic dissections comprising placing a stent in the true lumen and displacing the blood in the false lumen with an inflatable bag.

The invention belongs to the technical field of medical instruments, and particularly relates to a blood vessel inner false lumen blocking stent, comprising a stent body, a distal choke membrane, a proximal choke membrane, two circumferential blocking membranes, a release nut and a fixed bushing. The stent body is an expandable net body knitted by nickel-titanium alloy wire, and 2 to 4 layers of distal choke membrane are parallel mutually and are mounted inside the distal end of the stent body at intervals, thus, the multiple layers of distal choke membrane are used for preventing backflow ofdistal break blood; 2 to 4 layers of proximal choke membranes are parallel mutually and are mounted inside the proximal end of the stent body at intervals; the outer surfaces of two ends of the stentbody are covered with two circumferential blocking membranes circumferentially. The stent has excellent deformability and flexibility, good anchoring effect, cannot fall to aorta true lumen, can effectively prevent aorta distal break blood from flowing back to the false lumen, and is favorable for thrombus formation of the false lumen and remodeling of the true lumen.

The invention discloses a false lumen occlusion device which is a hollow cylinder structure as a whole; the outer wall of the cylinder structure is weaved with metal wires; the cross section of the cylinder structure is enclosed by a first edge having large curvature and a second edge having small curvature. In practical application contexts, one side, close to an original blood vessel wall, inside the false lumen is arc shaped, which has large curvature; while due to the elasticity or a little of tightness of an organ itself of a decollement part which has large curvature; therefore, the false lumen occlusion device of the invention is improved to be a semicircular column structure, which increases the fitting effect with the false lumen inner walls.

The embodiments of the invention provide a type B aortic dissection postoperative risk prediction method and device, and an electronic device, and relates to the technical field of medical images. Thetype B aortic dissection postoperative risk prediction method comprises the steps that firstly, a plurality of cases of preoperative three-dimensional angiography images are obtained, and all cases of the three-dimensional angiography images are pretreated to obtain a to-be-treated data set, wherein the to-be-treated data set comprises blood vessel true lumen information and blood vessel false lumen information; then the blood vessel true lumen information and the blood vessel false lumen information are subjected to vector analysis to obtain various image omics feature information, and the various image omics feature information is subjected to dimensionality reduction treatment and linear fitting to obtain risk factor variables; and finally, a risk predicting model is constructed according to the risk factor variables and a preset clinical lesion type. In this way, the risk probability of postoperative complications can be obtained, and thus patient safety is ensured.

The invention relates to the technical field of aortic dissection animal models and methods for manufacturing the same and provides a Stanford A type aortic dissection animal model and a method for manufacturing the same. Compared with the conventional method for manufacturing a Stanford A type aortic dissection animal model, the method for manufacturing a Stanford A type aortic dissection animal model, which is provided by the invention, has the advantages that the time for manufacturing the ascending aortic dissection is reduced and the success rate of manufacture of the Stanford A type aortic dissection animal model is increased. Meanwhile, the control to the false lumen length of the Stanford A type aortic dissection animal model lays an experiment foundation for the investigation of the Stanford A type aortic dissection pathogenesis and new therapeutic methods.

The invention belongs to the technical field of surgical medical training equipment, and relates to a manufacturing method of a personalized extracorporeal interlayer physical model.The method comprises the following steps of: manufacturing a three-dimensional geometric model based on a medical image, and carrying out smoothing treatment; manufacturing a bottom coating on the three-dimensional geometric model; forming a tearing opening in the bottom layer coating; carrying out surface modification or additional layer coating on a cut tearing-opening-shaped silica gel sheet, and attaching the silica gel sheet to a tearing opening; and manufacturing an outer coating on the bottom coating of the three-dimensional geometric model. According to the modeling method, the technical problem that a developable false lumen model cannot be manufactured in traditional cavity model manufacturing is solved; and meanwhile, a controllable false lumen triggering position and a controllable false lumen development path can be realized; and the aortic dissection model can be well manufactured according to the real size, and the clinical application value of the model is remarkably improved.

The invention provides a three-lumen balloon catheter to solve the problem that the balloon catheter does not have the cutting function in the prior art. A three-lumen balloon catheter, including a tube head, the proximal end of the tube head is connected to the balloon and the three-lumen tube, the three-lumen tube is connected to the outlet of the handle, the distal end of the balloon is tapered, and the boundaries on both sides of the balloon are respectively A developing material marking block is installed, and the proximal end of the balloon is connected to the outer layer of the three-lumen tube. The lumen of the three-lumen tube consists of a first lumen for the guide wire to pass through and a second lumen for drug injection. It is composed of a third cavity with a vascular knife, a knife storage area is provided at the far end of the third cavity, and the vascular knife is arranged in the knife storage area. The three-lumen balloon catheter can break through the intima into the true lumen during the interventional operation, incise or break through the intima of the false lumen as needed, and cut through the lumen of the diseased segment to avoid repeated withdrawal and puncture of the balloon catheter.

An implantable medical device (30) for treating aortic dissections includes a stent graft part (34) having a bulbous section (48) of greater radial diameter than the radial diameter of first and second sections (60,62) of the stent graft part (34). The bulbous section (48) is able to close off the false lumen (10) of an aortic dissection, thereby to prevent any fluid backflow into the false lumen (10). Radiopaque markers (70) may be provided for orientation and deployment purposes. The device (30) is able to treat chronic dissections and reduce false lumen backflow, which remains otherwise an unresolved issue in the endovascular treatment of false lumen aneurysms.

The present invention provides an application of aortic root angioplasty in Stanford type A aortic dissection clinical procedures. During the clinical treatment of Stanford type A aortic dissection, the premise of not using new surgical materials and increasing the cost of surgery It can basically eliminate the proximal dissection cavity of the aortic root, avoid anastomotic bleeding, avoid the compression of the coronary arteries by the proximal dissection cavity of the aortic root, and effectively avoid long-term false lumen caused by the proximal aortic root. There is formation of pseudoaneurysm caused by proximal neoplasia of the aortic root or anastomotic stoma. Reduce the possibility of bleeding while avoiding complications caused by massive blood transfusion, shorten the operation time, improve the success rate of the operation, reduce the difficulty of Stanford type A aortic dissection, and facilitate the promotion of Stanford type A aortic dissection and popularity.

The invention discloses a conformable and modular special occluder for promoting thrombosis of aortic dissection and false lumen, which is a three-piece structure, including a proximal part of the dissection false lumen, a middle part of the false lumen and a distal part of the false lumen. According to the different types of breaches at the distal end of the aortic dissection, the end-blocker is selectively combined with different parts and put into practical use. The present invention provides a conformable and modular special-purpose surface-modified and coagulation-promoting false lumen occluder for clinical use, which can be suitable for false lumens with various shapes and characteristics, effectively promotes the formation and reconstruction of false lumen thrombus, and is widely used ; The appropriate model can be selected according to the shape and size of the false cavity to reduce the economic burden and shorten the operation time. At the same time, a special release system is designed to accurately release and reduce damage to the false lumen, so as to better promote the thrombosis of the false lumen, improve the long-term therapeutic effect of the false lumen, and improve the overall prognosis of the dissection.

The invention discloses a microtubule assembly for coronary chronic total occlusion. The microtubule assembly for coronary chronic total occlusion comprises a microtubule body, a plurality of guide wires, a plurality of balloons and inflating pipelines of the balloons, wherein the specifications of the guide wires are different; the specifications of the balloons are different; each guide wire isdetachably and movably arranged in the microtubule body in a penetrating manner; each guide wire is located along the microtubule body in a stepping manner under the state that the guide wire is in the microtubule body; the balloons are detachably and movably arranged in the microtubule body in a penetrating manner, and each balloon is arranged along the microtubule body in a sliding manner underthe state that the balloon is located in the microtubule body; each balloon also communicates with the outer part of the microtubule body through the corresponding inflating pipe. The microtubule assembly for chronic total occlusion disclosed by the invention has the advantage that after wrongly entering a false lumen, the guide wire is easy to return to a true lumen; when the microtubule assemblyfor coronary chronic total occlusion is used for puncturing, microtubule assembly cannot be inserted deeply, and the situation that when a fiber cap is punctured, the blood vessel is punctured off isavoided; and the balloons are arranged, so that during operation, an appropriate balloon can be flexibly selected for use.

The invention relates to the field of a medical appliance, and particularly discloses an intraoperative freezing elephant trunk stent capable of realizing transesophageal ultrasound guided localization. The intraoperative freezing elephant trunk stent capable of realizing transesophageal ultrasound guided localization comprises an air guide tube and an air bag, wherein after passing through a holepassage of a stent body from top to bottom, the air guide tube communicates with an inner cavity of the air bag; and the air bag is of a flexible bag body structure and can be inflated to expand. Theguide-in and release of the stent body can be completed in an transesophageal ultrasound guided way; the hybrid operation is not needed; the popularization and the application are facilitated; in addition, the localization of the stent body is accurate; and the distal end of the stent body can be effectively prevented from entering the false lumen, so that the operation risk is reduced.

The present application provides a method and device for segmenting a dissecting artery, by acquiring an original CTA image of the aorta to be segmented; preprocessing the original CTA image to obtain a second target CTA image; using the artery segmentation model in the trained segmentation model and the chamber segmentation model, segment the second target CTA image to obtain a first structural model marked with the dissection aorta and branch arteries and a second structural model marked with the true lumen and false lumen on the dissection aorta; The first structural model and the second structural model are used to correct the misclassification of the true cavity and the false cavity on the second structural model. The present application standardizes the original CTA image, and uses the artery segmentation model and the chamber segmentation model to segment the standardized CTA image, which greatly reduces the image data that needs to be processed, effectively improves the efficiency of dissecting artery segmentation, and improves the the segmentation accuracy.

The invention provides an aortic dissection endoluminal repair postoperative false lumen blood flow state evaluation method, which comprises the following steps of: recoding, naming and sequencing a .IMA format file in a four-dimensional blood flow magnetic resonance imaging original file, and respectively exporting anatomical information and blood flow information contained in the .IMA format file; importing exported anatomical information and blood flow information data into an MATLAB platform to be preprocessed, processing original data through an autonomous coding program, and generating an .ENCAS format file; selecting an interested target blood vessel plane needing to be processed for analysis; selecting different blood flow parameters to calculate a time-varying quantitative relation of different blood flow dynamic parameters passing through normal aorta or real and false cavities of a dissection; and comparing different hemodynamic parameters in the true cavity and the false cavity in different planes as well as difference changes at different time points in a cardiac cycle, and analyzing hemodynamic parameters and a blood flow distribution mode in the false cavity after the aortic endoluminal repair.

The invention discloses a blood vessel constraining device which comprises a hollow cylindrical rigid frame. One radial side of the rigid frame is broken. The device further comprises an elastic body which is fixed between borders of the rigid frame and forms a semi-ring sleeve structure. The blood vessel constraining device can improve the tension stress performance of a vascular wall, angiectasis and angiorrhexis can be prevented, direct contact of instruments and blood vessel endothelium and blood is avoided, the blood and the blood vessel endothelium are protected, extracorporeal circulation is avoided, operation is easy, time is short, trauma is small, treatment effect can be greatly improved, meanwhile, a bare stent placed in a lumen can be combined for treating artery dissection, the inner portion and the outer portion of the vascular wall are clamped tightly, the mechanical strength of the vascular wall is improved, damage on an aorta intima is lowered, forming rate of inner membrane crevasses is lowered, inner leakage is avoided, the function of vessel inner membrane protecting is achieved, thrombus-causing rate can be lowered, the bare stent has no influence on blood supply of an aorta branch vessel, the occurrence rate of paraplegia is lowered, the implanting range is wide, a false lumen is fully closed, and the shortcoming that an existing later-period false lumen is not completely closed continuously is overcome.

The present invention discloses a catheter system, comprising: a catheter head having a lumen, a proximal end and a distal end, and an opening positioned at a bottom of the distal end; and a rotatable inner tube having a lumen positioned in the lumen and at a proximal end of the catheter head, the inner tube including a front end having an arcuate opening; wherein the rotatable inner tube can be rotated so that the arcuate opening thereon can be made to engage or disengage with the opening at the bottom of the distal end of the catheter head. The invention also provides a catheter system and method for re-entry of a vascular false lumen into a true lumen in a quick, accurate and low-risk way. The catheter system for re-entry of a vascular false lumen into a true lumen in a quick, accurate and low-risk way effectively solve the problems of difficult operation, inaccurate positioning, long operation time and easiness to cause acute occlusion and internal hemorrhage of the branch vessel when the guidewire is re-entering the true lumen in the prior art.

The invention provides an aortic dissection aneurysm covered stent which comprises a cylindrical metal supporting portion and a cylindrical covered portion coated on the cylindrical metal supporting portion. A bulging covered portion is coated outside the cylindrical covered portion, and the middle portion of the bulging covered portion bulges outwards. By adopting the above structure, a false lumen crevasse can be sealed and isolated, space of a false lumen can be actively reduced, blood flow speed and blood flow in the false lumen can be changed, and the false lumen is ensured to quickly form thrombus within expected time; the outwards-bulging portion can effectively prevent displacement and sliding caused by blood flow impact after the stent is implanted in a human body, and disease relapse caused by exposure of an original aortic crevasse due to displacement of the stent is avoided.

The invention provides an aortic dissection crevasse plugging device, and relates to the field of medical apparatus and instruments. The aortic dissection crevasse plugging device comprises a tubular grid stent and a plugging filling portion capable of preventing blood in an aortic true lumen from flowing into a false lumen from an intima crevasse; the plugging filling portion is connected to one side of the tubular grid stent; in the state that the aortic dissection crevasse plugging device is implanted into a human body and released, the tubular grid stent is supported on the inner wall of the aortic true lumen, a part of the plugging filling portion penetrates through the aortic intima crevasse to stretch into the false lumen and fill the false lumen, the plugging filling portion in the false lumen is supported on the inner wall of the false lumen, and the portion, connected with the plugging filling portion in the false lumen, of the tubular grid stent plugs the edge of the aortic intima crevasse. The aortic dissection crevasse plugging device at least solves the problems that in the prior art, when a covered stent, a grid stent, a plugging device and the like are used for treating an aortic dissection with an insufficient healthy anchoring area, a fragile intima needs to be expanded or a new crevasse is likely to be formed with the fragile intima as the anchoring area, and blood flow in the false lumen is difficult to suberize.

A blood catheter with a stent has a flexible tube body and an expandable stent structure. The tube body has a first open end for blood inflow and a second open end for blood outflow only; the stent structure is composed of a plurality of wires attached to the tube body, and the expansion direction of the stent structure body intersects with the tube body axis. There is a predetermined distance between the wire rod closest to the second open end in the stent structure and the second open end, thereby effectively preventing blood from flowing back into the false lumen through the new breach.