23 results about "Internal hemorrhage" patented technology

The invention relates to 4 serum peptide patterns for diagnostics of intracranial hemorrhagic stroke (ICH) in humans and differential diagnosis from acute ischemic stroke that are defined using a list of the 34 quantitative peptides that in sera of patients with ICH are increased 2 folds or more as compared with individuals without stroke and patients with acute ischemic stroke and a list of 16 qualitative peptides detectable in sera of the patients with ICH but not detectable in the sera of individuals without stroke and in sera of patients with acute ischemic stroke.

Embodiments of the present application relate to the field of measurement technology for diagnostic purposes, and particularly relate to an intracranial hemorrhage detection device and a containing part thereof. The containing part is used for mounting an antenna and a flexible headgear, and comprises a peripheral part, an end part, a plurality of antenna mounting parts and a headgear mounting part. The peripheral part is connected with the end part to jointly form a containing space for containing a patient's cranium. The headgear mounting part is used for mounting the flexible headgear in the containing space. Each antenna mounting part is used for mounting one antenna on the peripheral part to face the flexible headgear. Embodiments of the present application can mount the flexible headgear in the containing space by providing the headgear mounting part, and can mount the antenna on the peripheral part to face the flexible headgear by providing the antenna mounting part, thereby facilitating the assembly of the intracranial hemorrhage detection device. Moreover, the antenna can directly emit and receive microwave signals to and from the flexible headgear, and the transmission efficiency of the microwave signals can be improved through the flexible headgear.

The utility model discloses an internal fistula side limb fixer for a hemodialysis patient during defecation, which comprises a first fixing plate and a second fixing plate, a plurality of fixing seats are arranged on the first fixing plate and the second fixing plate, arc-shaped limiting rings are arranged on the fixing seats, and restraint straps are arranged in the arc-shaped limiting rings; shoulder straps are arranged at one ends of the first fixing plate and the second fixing plate. When the fixator is used, an internal fistula side limb can be placed in the fixator, and internal hemorrhage caused by excessive movement of the limb is prevented; the contact surface between the inner side of the fixator and the limbs is made of breathable perforated fabric which is comfortable and skin-friendly; a restraint strap and a first hook-and-loop fastener are arranged outside the fixator, the size of the fixator can be adjusted to be proper according to the size of the arm circumference of a patient, the shoulder strap is arranged, the limb on the internal fistula side can be kept in a straightened state when the patient goes to the toilet, and a puncture needle is better protected; the second hook-and-loop fastener can prevent the puncture needle from slipping due to the fact that the puncture needle is pulled when the patient goes to the toilet.

Processes are provided based on an interventional (device-based) approach to minimize the development of intramyocardial hemorrhage within the myocardial infarction (MI) zone. In one exemplary process, the revascularization occurs in an incremental fashion prior to fully opening the vessel, so as to modulate the hydrostatic pressure transmitted from the proximal end of the catheter, prior to placing a stent. In another exemplary process, the stent will be placed within the central core of the embolization and will slowly expand within the lumen reaching full patency over a period of time. Devices operated with these processes can also greatly reduce the chance of development of intramyocardial hemorrhage with the MI zone. These developments can improve the outcome in hemorrhagic patients, who otherwise carry a significant risk for heart failure and sudden death.

The invention discloses an application of sunitinib in preparation of a medicine for treating secondary injury caused by intracranial hemorrhage. It is found for the first time that sunitinib can act on a CSF-1R / PI3K / Akt axis, pathological activation and pro-inflammatory response of microglial cells are effectively inhibited, the normal phagocytic function and lipid metabolism balance of the microglial cells are remarkably recovered, myelin sheath damage around hematoma is effectively relieved, and the neurological function score, the movement coordination ability and the exploration behavior of ICH mice are remarkably improved; the progress of secondary injury caused by intracranial hemorrhage is hindered from multiple dimensions, the curative effect is superior to that of a positive control drug pecetinib (PLX3397), and a brand new molecular target and an interference strategy are provided for comprehensive treatment of ICH.

The invention discloses an application of a pyroptosis pathway inhibitor in protection of plateau brain impact lung injury, the pyroptosis pathway inhibitor is applied to preparation of a medicine for preventing and / or treating lung injury caused by plateau brain impact injury, the pyroptosis pathway inhibitor acts on a Caspase-1 / GSDMD signal pathway, the inhibitor comprises a Caspase-1 inhibitor, an ASC inhibitor or a GSDMD-D inhibitor, and the inhibitor comprises a Caspase-1 inhibitor, an ASC inhibitor or a GSDMD-D inhibitor. The medicine is used for improving lung function impairment caused by plateau brain impact injury. The lung function indexes comprise at least one of the maximum inspiration flow rate, the maximum expiration flow rate, the respiratory rate and the accumulated volume, and the medicine is used for relieving lung tissue pathological injury caused by the plateau brain impact injury; the pathological injury comprises at least one of pulmonary alveolar wall thickening, inflammatory cell infiltration, pulmonary alveolar cavity internal hemorrhage and pulmonary alveolar rupture and fusion into pulmonary bulla. The invention provides a new target spot and strategy for clinical prevention and treatment of the secondary lung injury of the plateau craniocerebral impact injury.

The present application relates to the technical field of medical image processing, and discloses a method and system for predicting vascular injury and assessing internal hemorrhage risk, comprising: acquiring original data, wherein the original data includes body surface marker coordinate data, physiological state and trauma-related information of a critically injured trauma victim; preprocessing the body surface marker coordinate data in the original data to obtain standardized coordinate data; inputting the standardized coordinate data into a pre-trained graph neural network model for mapping processing to obtain vascular marker three-dimensional coordinate prediction data; calculating the spatial distance between the injury path and the vascular marker according to the vascular marker three-dimensional coordinate prediction data and the trauma-related information to obtain a quantitative evaluation result of vascular injury risk; and combining the quantitative evaluation result of vascular injury risk with the physiological state information of the victim to complete comprehensive quantitative assessment of the internal hemorrhage risk of the victim to obtain a corresponding risk level result.

This invention relates to mitochondrial-enriched extracellular vesicles, their preparation methods, and applications, which can effectively solve the drug problem in spontaneous intracerebral hemorrhage. The technical solution involves using platelets as raw material, and obtaining platelet-derived extracellular vesicles carrying active mitochondria through activation induction, differential centrifugation and fractionation, membrane filtration and elution enrichment. This achieves efficient and stable loading of functional mitochondria, and the resulting PEV Mito has a complete structure and uniform particle size, which can effectively maintain mitochondrial membrane potential and biological activity. It can achieve efficient delivery and intracellular internalization to damaged neurons and restore mitochondrial function. The PEV Mito prepared by this invention has high delivery efficiency and excellent biocompatibility, and can be used to prepare drugs for the treatment of intracerebral hemorrhage and secondary neurological injury, with good prospects for clinical translation.

A wearable monitor is configured for early detection of internal bleeding events and particularly hematomas after vascular catheterization including cardiac catheterization. The wearable monitor is placed over an access location following the vascular catheterization procedure and the wearable monitor system periodically runs diagnostic test to detect changes in the tissue around the vascular access location. An emitter device may input an emitter input into the tissue and a detector device may then measure the emitter input after it has passed through the tissue, an emitter output. A computer may receive the data from the detector device and operate a program that determines changes in the tissue and in particular, pooling of blood in the tissue. The emitters may be electrodes that input an electromagnetic input, or an ultrasound emitter that inputs ultrasound sound waves, or a Near IR emitter that emits Near IR electromagnetic radiation.

The present invention provides a novel method to isolate and expand pure neural stem cells (NSCs) from cerebrospinal fluid (CSF) of premature babies with Intraventricular haemorrhage, which produces a population enriched in NSC-CSF cells free of contaminating fibroblasts and other cell types. The present invention also includes substantially pure populations of CSF-NSC cells, and their use to treat and prevent diseases and injuries, including Intraventricular haemorrhage and post- hemorrhage hydrocephalus / developmental deficits.

An ultrasound catheter with a lumen for fluid delivery and fluid evacuation, and an ultrasound source is used for the treatment of intracerebral or intraventricular hemorrhages. After the catheter is inserted into a blood clot, a lytic drug can be delivered to the blood clot via the lumen while applying ultrasonic energy to the treatment site. As the blood clot is dissolved, the liquefied blood clot can be removed by evacuation through the lumen.

A system for treating internal bleeding via application of a heated irrigant, such that the heated irrigant is delivered at a flow rate of between 2 cc / s and 12 cc / s and at a temperature of between 46 degrees Celsius and 52 degrees Celsius.

The invention discloses an intracranial hemorrhage CT image segmentation method and device, a medium and equipment, and relates to the technical field of image segmentation. In a segmentation threshold optimization process, a Bareones mechanism and an orthogonal learning mechanism are integrated into an African vulture optimization algorithm, a search space is expanded in a search population corresponding to a segmentation threshold through Gaussian mutation, and the ability of the threshold optimization algorithm to get rid of local optimum is enhanced; and an orthogonal learning mechanism promotes resource sharing among search population individuals corresponding to the segmentation threshold, and improves the search diversity of the segmentation threshold. And obtaining an optimal individual with the maximum Renyi entropy after the two-dimensional histogram is divided based on the threshold value through multi-round iterative optimization, and taking the optimal individual as an optimal segmentation threshold value of the intracranial hemorrhage CT image. According to the method, the population diversity and convergence speed in segmentation threshold optimization of the intracranial hemorrhage CT image are improved, and the image segmentation effect of the intracranial hemorrhage CT image is improved.

The application relates to the technical field of medical devices, in particular to a portable intraperitoneal hemorrhage qualitative detector, which comprises a detection control instrument, a detector is arranged on the front side of the detection control instrument, the detector comprises a detection assembly, a taking assembly is arranged on the top of the detection assembly; the detection assembly comprises a control assembly, a coupling agent smearing assembly is fixedly connected to the rear side of the control assembly. The detection control instrument and the detector are arranged, rapid and accurate qualitative detection of intraperitoneal hemorrhage is realized, the whole detection process has high automation degree, operation is simple, the detector has reasonable structure design, all components work cooperatively, after the electric push rod is started, a series of actions such as coupling agent smearing, detection head close to the detection position, qualitative detection, automatic resetting of all components after the detection is completed and the like can be sequentially completed, the detection efficiency is greatly improved, and the detection head is shielded after resetting, so that pollution or damage of the detection head due to exposure is effectively avoided.

The invention relates to the field of biological medicines, in particular to application of fullerene and fullerene derivatives in preparation of medicines, and the medicines are used for preventing, relieving, assisting in treating or treating intracranial hemorrhagic diseases. The invention finds that the fullerene and the fullerene derivative have excellent blood brain barrier crossing capability, can remarkably reduce neurotoxicity caused by intracranial hemorrhagic diseases such as cerebral hemorrhage and accelerate hematoma absorption, can be used for preparing medicines for preventing, relieving, assisting in treating or treating the intracranial hemorrhagic diseases, and has a wide application prospect. A new strategy and a solution scheme are provided for treatment of related diseases such as intracranial hemorrhagic diseases, and the application prospect is wide.

The embodiment of the invention provides a fundus image hemorrhage identification method and device, electronic equipment and a storage medium, and relates to the technical field of fundus image processing, and the method comprises the steps: obtaining a fundus image, and carrying out the preprocessing of the fundus image; extracting a bleeding area and a blood vessel area of the fundus image; calculating feature information of bleeding points in the bleeding area; wherein the feature information comprises hemorrhagic spot area, hemorrhagic spot number and hemorrhagic spot position; analyzing to obtain a fundus hemorrhage depth result according to the position relationship between the hemorrhage point and the blood vessel region; wherein the fundus hemorrhage depth result comprises one or more of intraretinal hemorrhage, supraretinal hemorrhage and subretinal hemorrhage; the fundus image is automatically processed and analyzed, the fundus hemorrhage position is obtained, the recognition precision and the recognition effect are improved, the risks of misdiagnosis and missed diagnosis are reduced, and therefore the diagnosis accuracy is improved.

A method for supporting diagnosis of intraventricular hemorrhage and early death within a week in very low birth weight infants based on deep learning includes a data collection step, a data preprocessing step, a learning step of training a prenatal prediction model, training a birth prediction model and training a postnatal prediction model, and a diagnosis step of, when a diagnosis target and diagnosis time are determined, selecting one prediction model based on the diagnosis time, analyzing medical information of the diagnosis target through the selected prediction model, and predicting and outputting the intraventricular hemorrhage diagnosis result.

The application discloses an intracranial hemorrhage CT image segmentation method and device, medium and equipment, and relates to the technical field of image segmentation. In the threshold segmentation optimization process, the Barebones mechanism and the orthogonal learning mechanism are integrated into the African vulture optimization algorithm. The search space is expanded in the search population corresponding to the segmentation threshold through Gaussian mutation, and the ability of the threshold optimization algorithm to get rid of local optimization is enhanced. The orthogonal learning mechanism promotes the resource sharing between the search population individuals corresponding to the segmentation threshold, and improves the search diversity of the segmentation threshold. Through multiple rounds of iteration optimization, the optimal individual that makes the Rényi entropy of the two-dimensional histogram based on the threshold segmentation maximum is obtained as the optimal segmentation threshold of the intracranial hemorrhage CT image. The application improves the population diversity and convergence speed in the threshold segmentation optimization of the intracranial hemorrhage CT image, and improves the image segmentation effect of the intracranial hemorrhage CT image.

Embodiments of the present application relate to the technical field of brain hemorrhage detection, and particularly relate to a method for determining brain microwave signal imaging, a system thereof, an intracranial hemorrhage detection device and a computer storage medium. The method for determining brain microwave signal imaging according to the embodiments of the present application comprises the following steps: obtaining brain microwave signals; filtering out clutter of the microwave signals to obtain only brain microwave signals; and determining brain signal imaging according to the obtained only brain microwave signals. The method provided by the embodiments of the present application can more clearly display the position of the hemorrhage area in the brain due to fewer clutter points of pixels in the brain imaging.

The utility model relates to the technical field of medical instruments, in particular to a uterine cavity drainage device for auxiliary suturing after delivery, which is characterized in that blood is drained into a drainage bag through a drainage cup and a drainage tube, and uterine bleeding is drained out of a body without passing through a vagina; a supporting part is arranged at the lower part of the drainage cup; the first balloon is arranged on the upper portion of the drainage cup, the second balloon and the third balloon are arranged on the lower portion of the drainage cup, the second balloon is arranged on the outer side of the supporting part, and the third balloon is arranged on the inner side of the supporting part; the first balloon, the second balloon and the third balloon contract to form a placement state, the first balloon expands, the second balloon and the third balloon contract to form a first auxiliary state, so that a receding space is formed between the lower portion of the drainage cup and the vagina, a good suturing view is provided, and the view does not need to be exposed through manual expansion; the first balloon, the second balloon and the third balloon expand to form a second auxiliary state, fixing and hemostasis are facilitated, and the problems that bleeding in the uterine cavity is not easy to observe, and gauze is left in the vagina are solved.

Methods of measuring the effects of an intracerebral hemorrhage are disclosed herein and include: acquiring at least one blood, serum, or plasma sample from a patient suffering from intracerebral hemorrhage, utilizing the at least one blood, serum, or plasma sample to isolate at least one neuron-derived extracellular vesicle, at least one oligodendrocyte-derived extracellular vesicle, at least one astrocyte-derived extracellular vesicle, or a combination thereof to form an extracellular vesicle isolate composition, analyzing the exosome isolate composition to identify at least one surface associated biomarker, wherein the at least one surface biomarker is located on the surface of the at least one neuron-derived extracellular vesicle, at least one oligodendrocyte-derived extracellular vesicle, the at least one astrocyte-derived extracellular vesicle, or the combination thereof, and quantifying the at least one surface biomarker to monitor post-hemorrhage cellular and molecular cascades in the patient.

The application discloses application of sodium butyrate in preparation of a medicine for treating intracranial hemorrhage, in particular, application of sodium butyate in preparation of a medicine for treating neonatal intraventricular hemorrhage, researches show that the sodium butyate is used for preventive neuroprotection of IVH of high-risk premature infants (fetal age is less than 32 weeks), secondary brain injury is reduced, and long-term neurodevelopmental outcome is improved; the sodium butyate is used for treating neonatal intraventricular hemorrhage, brain ventricle expansion is reduced, neuron survival is increased, and nerve function is improved; and the sodium butyate can also improve motor function and cognitive function, and has the effect of comprehensive neuroprotection. The application provides a new medicine source for treating intracranial hemorrhage, in particular, neonatal intraventricular hemorrhage.

This specification relates to an artificial hemostatic plug for stopping and / or preventing internal bleeding in a patient, more specifically, intrathoracic bleeding. The plug has a compressible plug body with a first end and a second end. The plug also has a thread slidably disposed through the plug body. The thread is also fixedly connected to the first end of the plug body, allowing the first end to be pulled toward the second end using the thread, which extends further outward from the plug body. This specification also includes a kit comprising the plug and a plug pusher.