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351 results about "Inner membrane" patented technology
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The inner membrane of the nuclear envelope is connected to the outer nuclear envelope membrane through nuclear pores. It contains a number of proteins involved in the structural organization of the nucleus and the attachment of chromatin to the nuclear envelope. In metazoan cells, the inner nuclear membrane contains proteins of the nuclear lamina, a protein meshwork underlying the nuclear envelope and providing structural support. Mutations in inner nuclear envelope proteins can cause nuclear envelopathies, a number of genetic disorders in humans.
Reusable analyte sensor site and method of using the same
A reusable analyte sensor site for use with a replaceable analyte sensor for determining a level of an analyte includes a site housing and a resealable insertion site coupled to one end of the site housing. Preferably, the site housing is formed to have an interior cavity, and includes an outer membrane made of a material selected to promote vascularization and having a first pore size, and an inner membrane made of a material selected to be free of tissue ingress. Also, the site housing permits the analyte to pass through the site housing to the interior cavity to permit measurement by the replaceable analyte sensor. The resealable insertion site is provided for inserting the replaceable analyte sensor into the interior cavity of the site housing.
Owner:MEDTRONIC MIMIMED INC
Device and method for exothermic treatment of eyelid diseases
ActiveUS20050119629A1Convenient procedurePreventing occurrence and recurrencePharmaceutical delivery mechanismMedical applicatorsDiseasePh control
Provided herein is a pad for treating eye conditions comprising a multipart container having an impermeable outer membrane sized to fit generally within the peri-orbital region and sufficiently flexible to mold to the eye; a first chemical in a first storage area in the multipart container; a second chemical in a second storage area in the multipart container, the first and second chemicals selected to have an exothermic reaction when mixed for producing a temperature suitable for treating eye conditions, the exothermic reaction providing the suitable temperature for a period of time suitable for treating eye conditions; and an inner membrane for initially separating the first and second chemicals, the inner membrane being renderable permeable, without causing the impermeable outer membrane to become permeable, to permit mixing the first and second chemicals to cause the exothermic reaction. This multipart container is covered with a soft, non-abrasive, lint-free material which is presoaked in a pH controlled antibacterial soap with or without an antibiotic.
Owner:OCUGIENE
Structural modification of 19-norprogesterone I: 17-α-substituted-11-β-substituted-4-aryl and 21-substituted 19-norpregnadienedione as new antiprogestational agents
The present invention relates, inter alia, to compounds having the general formula: in which: R1 is a member selected from the group consisting of —OCH3, —SCH3, —N(CH3)2, —NHCH3, —NC4H8, —NC5H10, —NC4H8O, —CHO, —CH(OH)CH3, —C(O)CH3, —O(CH2)2N(CH3)2, and —O(CH2)2NC5H10; R2 is a member selected from the group consisting of hydrogen, halogen, alkyl, acyl, hydroxy, alkoxy (e.g., methoxy, ethoxy, vinyloxy, ethynyloxy, cyclopropyloxy, etc.), acyloxy (e.g., acetoxy, glycinate, etc.), alkylcarbonate, cypionyloxy, S-alkyl, —SCN, S-acyl and —OC(O)R6, wherein R6 is a functional group including, but not limited to, alkyl (e.g., methyl, ethyl, etc.), alkoxy ester (e.g., —CH2OCH3) and alkoxy (—OCH3); R3 is a member selected from the group consisting of alkyl, hydroxy, alkoxy and acyloxy; R4 is a member selected from the group consisting of hydrogen and alkyl; and X is a member selected from the group consisting of ═O and ═N—OR5, wherein R5 is a member selected from the group consisting of hydrogen and alkyl.In addition to providing the compounds of Formula I, the present invention provides methods wherein the compounds of Formula I are advantageously used, inter alia, to antagonize endogenous progesterone; to induce menses; to treat endometriosis; to treat dysmenorrhea; to treat endocrine hormone-dependent tumors; to treat meningiomas; to treat uterine leiomyomas; to treat uterine fibroids; to inhibit uterine endometrial proliferation; to induce cervical ripening; to induce labor; and for contraception.
Owner:HEALTH & HUMAN SERVICES THE GOVERNMENT OF THE US SEC THE DEPT OF
Device and method for exothermic treatment of eyelid diseases
ActiveUS7211070B2Preventing occurrence and recurrencePromotes better eyelid hygienePharmaceutical delivery mechanismMedical applicatorsDiseasePh control
Provided herein is a pad for treating eye conditions comprising a multipart container having an impermeable outer membrane sized to fit generally within the peri-orbital region and sufficiently flexible to mold to the eye; a first chemical in a first storage area in the multipart container; a second chemical in a second storage area in the multipart container, the first and second chemicals selected to have an exothermic reaction when mixed for producing a temperature suitable for treating eye conditions, the exothermic reaction providing the suitable temperature for a period of time suitable for treating eye conditions; and an inner membrane for initially separating the first and second chemicals, the inner membrane being renderable permeable, without causing the impermeable outer membrane to become permeable, to permit mixing the first and second chemicals to cause the exothermic reaction. This multipart container is covered with a soft, non-abrasive, lint-free material which is presoaked in a pH controlled antibacterial soap with or without an antibiotic.
Owner:OCUGIENE
Micro-Valve
InactiveUS20100137784A1Accurately defined activation pressurePrecise definitionDiaphragm valvesEngine diaphragmsInner membraneBiomedical engineering
A one-way valve comprises a seat and a membrane having an inner portion that is stretched over the seat, wherein, in use, the inner membrane portion is selectively deflected from the seat such that a fluid path is created from one side of the membrane to the other so as to open the valve, and wherein an outer peripheral portion of the membrane is stiffer than the inner portion such that the membrane deflection is substantially restricted to only the inner portion. The one-way valve may be used in a pump for an infusion system.
Owner:INSULET NETHERLANDS BV
Needle amperometric determination type glucose sensor for subcutaneous tissue real-time monitoring and manufacturing method thereof
ActiveCN101530327AShort response timeStable jobDiagnostic recording/measuringSensorsGlucose sensorsConcentrations glucose
The invention discloses a needle amperometric determination type glucose sensor for subcutaneous tissue real-time monitoring and manufacturing method thereof. The sensor comprises a needle reference electrode (2) and at least one needle working electrode (1) including a conducting layer (8) and an enzyme membrane layer (6), and is characterized in that the working electrode (1) further comprises a polymer material inner membrane layer (7) and a polymer material control diffusion layer (5), and the conducting layer (8), the polymer material inner membrane layer (7), the enzyme membrane layer (6) and the polymer material control diffusion layer (5) are coated in turn from inner to outside. According to the manufacturing method in the invention, the glucose sensor has good stability, high flexibility, wide linear range of output current and glucose concentration, short response time, continuous real-time monitoring, good fastness and stability of enzyme bonding, high flexibility, selectivity and repeatability.
Owner:HUZHOU MEIQI MEDICAL EQUIP CO LTD
Water and oil separation system
ActiveUS20130146536A1Efficiently and completely performReduce dirtSedimentation separationLoose filtering material filtersOil separationInner membrane
A separation system includes at least a hydrocyclone and one or more membranes. In another aspect, a separation system includes a membrane having graduated and / or asymmetrical pore sizes. A further aspect of a separation system includes an inner membrane, an outer membrane and a hydrocyclonic flow between the membranes.
Owner:BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIV
Device and methods for the production of chlorine dioxide vapor
InactiveUS20060039840A1High moisture levelRapid productionDeodrantsGas generation devicesChlorine dioxideLiquid water
A device for producing chlorine dioxide vapor in a time release manner when exposed to ambient moisture is provided. The device comprises two outer membranes and an inner membrane. The outer and inner membranes are sealed together along the edges of the device. The outer and inner membranes together form a pouch comprising two separate compartments separated by the inner membrane. Each compartment is provided with a dry reactant (e.g. an acid component and a metal chlorite component) for producing chlorine dioxide vapor. The outer membranes are permeable to moisture and chlorine dioxide vapor, and impervious to liquid water and the dry reactants. The acid component in one of the compartments is hydrated by the moisture penetrated through the outer membranes, and the hydrated acid component is absorbed by the inner membrane and transported across the inner membrane to come into contact with the metal chlorite component in the other compartment to produce chlorine dioxide vapor. The chlorine dioxide vapor eventually slowly diffuses out of outer membranes into the surrounding environment.
Owner:AVANTEC TECH
Carbidopa/Levodopa gastroretentive drug delivery
A gastroretentive drug formulation for the sustained release of an active agent in the gastrointestinal tract comprises an internal layer or compartment comprising an active agent and one or more pharmaceutical excipients, of which at least one is a polymer and two membranes forming together an envelope around the inner membrane, each membrane comprising at least one polymeric combination of an enteric polymer which is not soluble in gastric juice, and an hydrophilic swelling polymer, and at least one plasticizer.
Owner:INTEC PHARMA
Device for proactive modulation of cardiac strain patterns
ActiveUS20050004420A1Maintain strainReduces apoptosis in the myocardiumHeart valvesIntravenous devicesCardiac muscleApoptosis
A direct cardiac assist device which may aid in ventricular recovery. The device proactively modulates cardiac strain pattern to produce a contraction strain pattern that induces beneficial growth and remodeling of the myocardium or prevents or reduces apoptosis of the myocytes. The device may include an outer shell. membrane, or mesh and an inner membrane. The space between the outer member and the membrane may be filled with fluid that is pressurized during contraction. The device prescribes a beneficial strain pattern during heart contraction. This strain pattern does not invert the curvatures or grossly alter the curvatures of the heart and may assist in myocyte regrowth and healing of the failing heart.
Owner:TEXAS A&M UNIVERSITY
Ballistic fire protection packaging system
Owner:THE BOEING CO
Segmentation method for inner membrane in blood vessel of intravascular unltrasound image
ActiveCN107909585AMultiple learning opportunitiesEasy to identifyImage enhancementImage analysisComputer visionInner membrane
The invention discloses a segmentation method for an inner membrane in a blood vessel of an intravascular unltrasound image. The method comprises the steps of S1, collecting intravascular unltrasoundimage data, and marking a central inner membrane area in each intravascular unltrasound image; S2, performing polar coordinate transformation on a training set image; S3, computing an edge distance map of a mark chart; S4, setting a sliding clamping window and determining the size of the window and a sliding step length; S5, building and training a FusionNet deep learning segmentation model; and S6, inputting new data and acquiring a segmentation result. The method provided by the invention, the inner membrane area in the blood vessel can be quickly, accurately and effectively extracted.
Owner:SOUTH CHINA UNIV OF TECH
Compound medicament intravascular stent and preparation method thereof
ActiveCN101327343ANo effect on mechanical propertiesEffect on mechanical propertiesStentsSurgeryBiocompatibility TestingThrombus
The invention relates to a composite drug stent and a preparation method thereof. The stent includes a stent body and active drugs; wherein, the stent body is a perforated medical material with good biocompatibility, which can be made by optionally using stainless steel, cobalt-based alloy, titanium alloy, nickel-titanium alloy, or polylactic acid bio-polymer material; the active drugs include special endothelial progenitor cell antibody drug and anti-smooth muscle cell proliferation drug. The internal surface of the perforated stent body is fixedly provided with the special endothelial cell antibody drug, while the external surface of the perforated stent body is coated with the anti-smooth muscle cell proliferation drug. The preparation method includes as follows: (1) pretreating the surface of the stent body; (2) making holes; (3) post-treating the surface of the stent body; (4) dispensing medicines; (5) coating the external surface; (6) fixing the internal surface; (7) drying at low temperature. The preparation method can selectively absorb endothelial progenitor cells and facilitate in repairing endodermis, and can effectively inhibit the proliferation and migration of vascular smooth muscle cells, persistently and effectively reduce the newborn endangium, effectively prevent the stent from narrowing, and avoid the risk of tardive thrombosis.
Owner:LEPU MEDICAL TECH (BEIJING) CO LTD
Supporting frame capable of being taken out
InactiveCN102038564AEasy to take outImprove flexibilityStentsSurgeryNasal cavityExternal Auditory Canals
The invention relates to a supporting frame capable of being taken out. In the invention, a sandwich structure that a support is arranged between an inner membrane and an outer membrane is adopted; the connection part of the inner membrane and the outer membrane is opposite to a mesh of the supporting frame; and the supporting frame can freely wriggle in the space formed by the disconnection part of the inner membrane and the outer membrane, therefore, the supporting frame capable of being taken out, provided by the invention, has particularly good flexibility; a full covering membrane structure is adopted to ensure that granulation tissues cannot grow into the supporting frame; and a detachable design is adopted to ensure that the supporting frame can be conveniently taken out. The supporting frame capable of being taken out can be used for inducing and promoting the growth of a neonatal cavity tube, the covering and the epithelization of a mucous membrane, can be conveniently taken out and detached under the direct vision of an endoscopy after the mucous membrane of the neonatal cavity tube is epithelized and the organization is stable, and can be used for a temporary support under the situations of esophagus rebuilding and injury repairing, trachea rebuilding and injury repairing, urethra rebuilding and injury repairing, esophagus-esophagus anastomosing, intestine-intestine anastomosing, nasal cavity rebuilding and injury repairing, external auditory canal rebuilding and injury repairing and the like.
Owner:周星
Method for manufacturing high-energy-density and high-power-density asymmetric supercapacitor based on eggshell inner membranes
InactiveCN103258654AHigh specific capacitanceIncrease energy densityHybrid/EDL manufactureHigh energyCarbonization
The invention discloses a method for manufacturing a high-energy-density and high-power-density asymmetric supercapacitor based on eggshell inner membranes. According to the manufacturing method, after carbonization and activating treatment in the air are carried out on one eggshell inner membrane, the eggshell inner membrane serves as negative electrode material of the supercapacitor, after carbonization and activating treatment in the strong alkaline environment are carried out on one eggshell inner membrane, MnO2 nano particles grow on the eggshell inner membrane to serve as positive electrode material of the supercapacitor, the eggshell inner membrane without treatment serves as a diaphragm, a Na2SO4 neutral solution serves as an electrolytic solution, and the asymmetric supercapacitor is assembled. The asymmetric supercapacitor based on the eggshell inner membranes has the advantages of being high in energy density, high in power density, safe to use, low in cost, environment-friendly and the like, cycling stability of the asymmetric supercapacitor reaches a usage level, and the eggshell inner membranes can be recycled as daily household garbage.
Owner:SOUTHWEST UNIV
Carbidopa/lipodopa gastroretentive drug delivery
A gastroretentive drug formulation for the sustained release of an active agent in the gastrointestinal tract comprises an internal layer or compartment comprising an active agent and one or more pharmaceutical excipients, of which at least one is a polymer and two membranes forming together an envelope around the inner membrane, each membrane comprising at least one polymeric combination of an enteric polymer which is not soluble in gastric juice, and an hydrophilic swelling polymer, and at least one plasticizer.
Owner:INTEC PHARMA
Method for producing polymer membrane silver ion selective electrode
InactiveCN101750444ASolution to short lifeLow detection limitMaterial analysis by electric/magnetic meansPolyvinyl chlorideIon exchange
The invention discloses a method for producing a polymer membrane silver ion selective electrode. Crown ether compound which comprises amide groups and sulfur heteroatoms is used as silver ion carrier and is mixed with polyvinyl chloride, plasticizer and ion exchanging agent according to a certain proportion. Inorganic salt which comprises anions which can form slightly soluble matters with silver ions is used to adjust the concentration of interfering ions and main ions in internally filled liquid. The polymer membrane silver ion selective electrode membrane forming and activating conditions are optimized, the seepage of main irons of an inner membrane phase to sample solution is effectively reduced, and the polymer membrane silver ion selective electrode detection limit is made to comply with theoretical prediction value (less than 10-10mol / L). The polymer membrane silver ion selective electrode has good silver ion nernst response and silver ion selectivity. The method for producing the polymer membrane silver ion selective electrode overcomes the defect that the complexing agent used for the internally filled liquid of a polymer membrane electrode of low detection limit is easy to seep into a polymer membrane and the iron exchange resin is hard to miniaturize. The performance of the polymer membrane silver ion selective electrode can not be reduced in one month.
Owner:YANTAI INST OF COASTAL ZONE RES CHINESE ACAD OF SCI
Sealing gland
A sealing gland for sealing between an elongate member and a surface through which the member extends, the gland comprising a sealing body having an inner membrane for sealing about the elongate member and an outer peripheral region for sealing against the surface. The inner membrane has one or more cut guides on an underside of the membrane arranged to locate adjacent the surface in use. Each cut guide represents a known elongate member option and facilitates the formation of an aperture through the membrane for suitably receiving the associated elongate member option there through in use. A compression ring is also provided to couple the surface over the sealing body to compress the sealing body in use and form an effective seal.
Owner:LAKE PROD
Second-order-odd-repetitive-controller-based odd harmonic current suppression method of magnetic levitation rotor
ActiveCN106886152AWiden the upper limit of the valueSuppress harmonic currentAdaptive controlHysteresisHarmonic mitigation
The invention discloses a second-order-odd-repetitive-controller-based odd harmonic current suppression method of a magnetic levitation rotor. A magnetic levitation rotor kinetic model including rotor mass unbalance and sensor harmonic is established; and a second-order-odd-repetitive-controller(SOORC)-based odd harmonic current suppression method of a magnetic levitation rotor is employed. The SOORC has a second-order inner membrane structure for odd harmonic frequency suppression, so that the harmonic suppression capability on a harmonic frequency changing or uncertain condition can be improved and thus the control robustness of the system for the harmonic frequency changing or uncertain condition can be improved. With phase hysteresis-lead compensation, the steady performance and dynamic performance of the system are improved, so that odd harmonic current components generated by a magnetic bearing coil in a magnetic levitation rotor can be suppressed. The method is suitable for suppression of odd harmonic current components of the magnetic levitation rotor system with rotor mass unbalance and sensor harmonic.
Owner:BEIHANG UNIV
Reversible crosslinked biodegradable polymer vesicle having positive charges on inner membrane, preparation method thereof and application in preparation of antineoplastic drugs
ActiveCN106137968AEfficient specific bindingEfficient combinationPharmaceutical non-active ingredientsAntineoplastic agentsTumor targetingApoptosis
The invention discloses a reversible crosslinked biodegradable polymer vesicle having positive charges on an inner membrane, a preparation method thereof and application in preparation of antineoplastic drugs. The biodegradable polymer vesicle based on tumor targeting of a block polymer PEG-P (TMC-DTC)-SP or PEG-P (LA-DTC)-SP, having the positively charged membrane, reversibly crosslinked in reduction sensitivity and intracellularly solvable and crosslinked can effectively support and protect biological macromolecules such as proteins, DNA and siRNA and micromolecular drugs with negative charges in a physical environment and can be delivered to intravital tumor cells to induce apoptosis. The system has lots of unique advantages including simple and easy controllability of preparation, excellent biocompatibility, excellent controlled drug release property, super-strong in-vivo circulation stability, superior cancerous cell targeting and remarkable cancer cell apoptosis capability and the like. Therefore, the reversible crosslinked biodegradable polymer vesicle is expected to become a simple, stable, multifunctional nano system platform integrating multiple advantages and is used for efficient, active and targeted delivery from nucleic acids to in-situ tumors.
Owner:SUZHOU UNIV
Thrombus fetching device with multi-spiral structure
The invention relates to a thrombus fetching device with a multi-spiral structure. The thrombus fetching device comprises a first driving part, a second driving part, an inner catheter, an outer catheter, a near-end marking ring, a far-end marking ring, a guide sleeve, and a spiral guide wire. The thrombus fetching device has the advantages that the structure of a spring stent is similar to the structure of a self-expanding stent; when the spring stent is released, compared with the existing self-expanding stent, the wall attaching property is better; when the spring stent is released, the structure in contact with the inner wall of a blood vessel is a round and smooth spiral guide wire, so that compared with the existing self-expanding stent, the injury to the blood vessel is less, and the pain of a patient is furthest reduced; the spring stent can be completely released in the blood vessel, so that when the spring stent is retracted, the spring stent can thoroughly fetch the thrombus, and the spiral guide wire of the spring stent can be spirally retracted and closed, thereby furthest preventing the falling of thrombus spots; after the spring stent is released from the guide sleeve, the spring stent can be quickly and naturally expanded to fill the inner wall of the blood vessel, the process is equivalent to performance of one-time stent-assisted angioplasty, the blood flow can be instantly restored, and the injury to the inner membrane of the blood vessel is avoided.
Owner:THE FIRST AFFILIATED HOSPITAL OF ZHENGZHOU UNIV
Intravascular ultrasound image segmentation method
An intravascular ultrasound image segmentation method includes the steps: determining seed points of blood vessel lumens and seed points of the outer wall of a blood vessel; obtaining probability images of the seed points of a first blood vessel lumen and the seed points of the outer wall of the blood vessel; obtaining a first gradient image of a intravascular ultrasound image; processing a threshold of the probability image of the seed points of the outer wall of the blood vessel to obtain a first sequence threshold image; determining an outer membrane boundary of the blood vessel according to the first sequence threshold image and the first gradient image; taking second communication area boundary pixels as seed points of a media; obtaining probability images of the seed points of a second blood vessel lumen and the seed points of the media; obtaining a second gradient image of the intravascular ultrasound image; processing a threshold of the probability image of the seed points of the second blood vessel lumen to obtain a second sequence threshold image; and determining an inner membrane boundary of the blood vessel according to the second sequence threshold image and the second gradient image. The probability of the probability images of the seed points of the blood vessel lumens in a second communication area is higher than 0.5.
Owner:UNIV OF SHANGHAI FOR SCI & TECH +1
Sealing gland
A sealing gland for sealing between an elongate member and a surface through which the member extends, the gland comprising a sealing body having an inner membrane for sealing about the elongate member and an outer peripheral region for sealing against the surface. The inner membrane has one or more cut guides on an underside of the membrane arranged to locate adjacent the surface in use. Each cut guide represents a known elongate member option and facilitates the formation of an aperture through the membrane for suitably receiving the associated elongate member option there through in use. A compression ring is also provided to couple the surface over the sealing body to compress the sealing body in use and form an effective seal.
Owner:LAKE PROD
Method for rapidly preparing supported zeolite inner-membranes
The invention discloses a method for rapidly preparing supported zeolite inner-membranes, which is characterized in that the method comprises the following steps: a, hermetically protecting the outer surface of a carrier pipe by using a zeolite inner-membrane fixing assembly consisting of a fixed supporting panel, a protective casing and a connecting seal component firstly, then introducing large zeolite seed crystals to the inner surface of the carrier pipe through a dip coating method so as to block an orifice of the inner surface of a carrier, and modifying the carrier pipe by using small zeolite seed crystals through the dip coating method, and finally, forming an ultrathin seed crystal layer on the inner surface of the carrier pipe; and b, hermetically protecting the outer surface of the carrier pipe pre-coated with seed crystals by using the zeolite inner-membrane fixing assembly, horizontally placing the carrier pipe in a crystallization kettle, and slowly injecting crystallized reaction liquid into the crystallization kettle to carry out crystallized synthesis; and after the crystallized synthesis is completed, quenching the crystallization kettle, and after a prepared membrane is taken out, cleaning and drying the membrane so as to obtain a supported zeolite inner-membrane. The method disclosed by the invention can carry out rapid batch preparation on one or more single-channel and multi-channel supported zeolite inner-membranes.
Owner:CNOOC TIANJIN CHEM RES & DESIGN INST +1
Microorganism comprising particles and uses of same
A particle is disclosed. The particle comprising: (i) at least one inner core which comprises a solid matrix of nutrients for microorganism growth; (ii) an inner membrane being fabricated from a water-soluble polymer, the inner membrane surrounding the inner core and a population of dried microorganisms; and (iii) an outer porous membrane surrounding the inner membrane, the outer porous membrane being insoluble in water. Methods of generating same, propagating microorganisms within and uses of same are also disclosed.
Owner:MENASHE OFIR
Method for detecting compaction degree of screen in flat plate reverse osmosis or nano-filtration membrane equipment
InactiveCN101545797AQuickly diagnose tightnessDiagnosis is tightWater/sewage treatment bu osmosis/dialysisMachines/enginesFiltration membraneGraduated cylinder
The invention relates to a method for detecting the compaction degree of a screen in a flat plate reverse osmosis or nano-filtration membrane equipment. The method comprises the following steps: assembling an entering water screen, a flat plate reverse osmosis or nano-filtration membrane sheet, and certain number of generated water screens or entering and generated water mixed screens; adopting tap water without active chlorine as entering water, and operating for certain period of time in a mode of complete cycle so that a reverse osmosis system is operated; after parameters of the generated water are stable, reducing the pressure of the system, closing a generated water valve, opening a resorption pipeline valve, and then turning off a high-pressure pump; and using the pressure difference between a measuring cylinder in a resorption pipeline and an inner membrane of flat plate equipment in the process of stopping the pump to detect the liquid level descending of the measuring cylinder so as to judge whether the screen in the flat plate membrane equipment is compacted tightly, wherein greater amplitude of the liquid level shows that the membrane screen is not compacted tightly, and no descending of the liquid level shows that the screen is compacted tightly.
Owner:浙江凯锐环保股份有限公司
Histidine-tagged intimin and methods of using intimin to stimulate an immune response and as an antigen carrier with targeting capability
InactiveUS6942861B2Lessens seriousnessPromotion of protective immune responseAntibacterial agentsOrganic active ingredientsAntigenInner membrane
The present invention describes the isolation and purification of histidine-tagged functional portions of intimin (his-tagged intimin or his-intimin), a protein associated with the ability of certain strains of pathogenic bacteria to adhere to epithelial cells. The invention further describes the use of intimin as an antigen to promote a protective immune response. In addition, the invention describes the combination of intimin with one or more other antigens and administration of the combination to promote a protective immune response against intimin and the one or more antigens.One aspect of the invention is the administration of intimin to target specific epithelial cells to promote a protective immune response to intimin proteins. Additional aspects of the invention include the use of intimin or intimin combined with one or more antigens and administration of the combination to target gastrointestinal mucosa and stimulate an immune response. Additionally, the invention describes administration of the combination of intimin combined with drugs, to provide a means for targeted delivery of drugs to specific epithelial cells. Other aspects of the invention include the production of antibodies directed against his-intimin and methods of using such antibodies to provide passive immune protection, and in an assay system.
Owner:THE HENRY M JACKSON FOUND FOR THE ADVANCEMENT OF MILITARY MEDICINE INC
Biology polypeptide medicament blood vessel bracket and preparation method thereof
ActiveCN101313873ANo effect on mechanical propertiesEffect on mechanical propertiesStentsOrganic active ingredientsProgenitorBiopolymer
The invention relates to a biologic polypeptide medicine blood vessel support and a preparation method thereof. The biologic polypeptide medicine blood vessel support comprises a support body and active medicines. The support body which is medical material with pores and good biocompatibility is made from stainless steel, cobalt-base alloy, titanium alloy, nickel-titanium alloy or polylactic acid biopolymer; the active medicines comprise a biologic polypeptide medicine and a smooth muscle cell proliferation inhibition medicine. The support is characterized in that: the support body with the pores has the biologic polypeptide medicine fixed on the internal surface of the body and the smooth muscle cell proliferation inhibition medicine coated on the external surface of the body. The preparation me(3) carrying out the after-treatment of the surface of the support body; (4) preparing the medicines; (5) coating the external surface; (6) fixing the medicine onto the internal surface; (7) carrying out the process step of low temperature drying. The support can selectively absorb endothelium progenitor cells which quickly differentiate into endothelium cells to promote the restoration of the endothelium after the support is built in; the support can also effectively inhibit the proliferation and migration of vascular smooth muscle cells, persistently and effectively reduce the formation of a new inner membrane, effectively prevent restenosis inside the support, and avoid the risk of potentially fatal late thrombosis.
Owner:乐普(深圳)国际发展中心有限公司
Process of windowing breeding egg and hatching chicken embryo
The present invention discloses process of windowing hatching egg and hatching chicken embryo, and the process includes windowing hatching egg, embryo operation, sealing and hatching. The present invention features the windowing hatching egg including sterilizing hatching egg, cutting one or several polygonal or circular slots without opening the inner membrane, cutting the inner membrane in bacteria-free condition, and turning the cut inner membrane for convenient embryo operation. Compared with available technology, the present invention has the advantages of simple operation and capacity of reaching hatching rate over 50 %.
Owner:湖南省畜牧兽医研究所
Metallic blood vessel bracket coating for osamine glycan load CD133 antibody and method for preparing the same
InactiveCN101172168AMeet shelf life requirementsGood biocompatibilitySurgeryCatheterHuman bodyVascular endothelium
Owner:DALIAN UNIV OF TECH
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