The invention relates to a mouse
spinal cord injury bionic compression modeling
system and a method thereof.The
system comprises a mechanical arm, a
magneto-rheological-pneumatic loading compression module, a multi-mode
optical fiber sensing probe and a control module, the
magneto-rheological-pneumatic loading compression module comprises a shell, an air bag, a
magneto-rheological
elastomer and an air supply part, the shell is installed at the driving end of the mechanical arm, and the air bag is installed at the driving end of the mechanical arm; the air bag is installed in an inner cavity of the shell, the electromagnetic part is fixedly installed at the bottom of the inner cavity of the shell, the air supply part supplies air to the air bag, and the
magnetorheological elastomer is fixedly installed at the end, away from the bottom of the shell, of the air bag. The multi-mode
optical fiber sensing probe is installed at the end, away from the air bag, of the
magnetorheological elastomer and used for detecting the microenvironment of the deep
spinal cord tissue of the mouse. The injured
spinal cord chronic compression
animal model constructed by the scheme is high in fidelity, the
clinical correlation of the model can be remarkably improved, and the experimental variability is reduced, so that a more reliable and more comprehensive research platform is provided for mechanism research and
treatment strategy evaluation of degenerative spinal cord diseases.