97 results about "Biological property" patented technology

A method for computational drug design includes defining a population of a plurality of compounds. Each compound includes one or more molecular properties. The method includes defining a training set of compounds from the population for which one or more biological properties are known. The method includes selecting, from the population, a subset of one or more compounds that are not in the training set. The method includes determining a subset score of the selected subset based on molecular properties of the one or more compounds in the selected subset, and evaluating the selected subset based on the determined subset score. The subset score is determined based on a frequency of the molecular properties in the population and on a frequency of the molecular properties in a sampled set comprising the training set and the selected subset.

The invention relates to the technical field of agricultural resources and environment, and particularly discloses a rapid fertilization improvement method for newly-reclaimed red soil dry land. The method systematically integrates the core steps of soil diagnosis aluminum toxicity passivation, composite conditioner deacidification, two-stage deep ploughing, organic and inorganic biological synergistic fertilization, soil moisture content regulation and control, earth surface covering, green manure planting and returning to the field and the like. The applied composition comprises a soil composite conditioner, a charcoal-based organic fertilizer and a specific functional microbial agent, wherein the soil composite conditioner comprises modified oyster shell powder, a calcium magnesium phosphate fertilizer, humic acid, polyglutamic acid and the like. The method relates to key processes such as temperature programming calcination modification of raw materials, co-pyrolysis and composite granulation of the materials and the like. The method can synchronously and quickly improve the chemical and biological properties of soil and optimize the physical structure of a plough layer, and has the advantages of high improvement targeting, synergistic interaction of all steps, high fertilizing speed and lasting effect; in addition, the method has the advantages of being coherent in process, high in resource utilization efficiency and easy to implement on a large scale.

Novel compositions of recombinant human CC10 protein have been generated by chemically modifying the pure protein in vitro. Several new synthetic preparations containing isoforms of chemically modified rhCC10 have been generated by processes that utilize reactive oxygen species and reactive nitrogen species. These preparations contain novel isoforms of rhCC10 which have been characterized with enhanced or altered biological properties compared to the unmodified protein. Preparations containing novel isoforms may be used as standards to identify and characterize naturally occurring isoforms of native CC10 protein from blood or urine and ultimately to measure new CC10-based biomarkers to assess patient disease status. These preparations may also be used to treat respiratory, autoimmune, inflammatory, and other medical conditions that are not effectively treated with the unmodified protein.

The application discloses an application method of leguminous green manure combined with growth-promoting bacteria for emission reduction and efficiency increase, and relates to the technical field of crop planting. The method comprises the following steps: sowing black bean seeds in soil inoculated with bacillus velezensis, and culturing black bean plants to the full flowering stage, and then crushing and turning over the black bean plants as green manure. A special bacillus velezensis is separated, which has the effects of bacteriostasis, nitrogen fixation, phosphorus dissolution, potassium solution, biofilm formation and auxin production, and has excellent biological characteristics such as stress resistance, rapid growth and easy separation, and the advantages of easy cultivation, safety, harmlessness and no pollution. Meanwhile, the bacillus velezensis can ferment to produce rich metabolic products, has good antibacterial activity and stress resistance. The bacillus velezensis is particularly suitable for being combined with black beans for green manure cultivation, and can maximize the effects of soil fertilization and gas emission reduction of green manure.

The invention relates to the field of soil mite classification, and discloses a soil mite extractor capable of autonomously detecting types and quantity, which comprises an extractor bracket, an extraction funnel, a crawling channel, an alcohol collecting vessel, an insect expelling lamp, a micro-object camera, an image processor and a display. During working, a collected soil sample is placed in the extraction funnel, and the mites are driven to move downwards and enter the crawling channel through light and thermal stimulation provided by the trapping light source located above the extraction funnel by utilizing the biological characteristics of light and heat resistance of the soil mites. The micro-object camera shoots mites passing through the channel in real time and transmits a video stream to the image processor. A trained image detection algorithm is built in the image processor, and the types and the number of mites in the video are automatically recognized. According to the method, the problem that time and labor need to be consumed for manual counting in traditional soil mite recognition is solved, automation and visualization of the extraction and statistical process are achieved, and the working efficiency is remarkably improved.

The invention relates to the field of plant ecological risk assessment, and discloses a foreign mangrove species ecological influence assessment and risk prediction method, which comprises the following steps: performing biological characteristic information investigation and analysis on target foreign mangrove species to construct a multi-dimensional assessment index system, and performing risk judgment on the target foreign mangrove species according to different index score values, given by the system, of the target foreign mangrove species. And evaluating a risk evolution process after the risk judgment, and outputting a management scheme for the risk. According to the method, the comprehensive influence of external mangrove species can be comprehensively and comprehensively evaluated, key risk points are not missed, meanwhile, the management efficiency is improved, and the decision randomness and uncertainty are reduced.

The invention discloses sinorhizium xinjiangense APXJHT24-1 which has the functions of promoting growth and inhibiting aspergillus flavus, and the preservation number of the sinorhizium xinjiangense APXJHT24-1 is CCTCC (China Center for Type Culture Collection) M 2026229. According to the invention, the integration of two major functions of'generation of a characteristic antibacterial volatile matter of dimethyl disulfide 'and'efficient symbiotic nitrogen fixation' on a single strain is realized in Sinkiang Sinkiang rhizobium for the first time. The dimethyl disulfide released by the strain can accurately down-regulate expression of toxin synthesis key genes and spore development core genes in the aspergillus flavus, so that efficient bacteriostasis is realized on the molecular level. Through one-time inoculation, the strain can synchronously achieve the dual purposes of growth promotion and nitrogen fixation and source bacteriostasis at the rhizosphere ecological niche of the peanuts. Especially aiming at the biological characteristics of overground flowering and underground fruiting of peanuts, a lasting biological fumigation protection layer can be formed in a soil microenvironment in a legume development critical period.

The invention provides a bacillus high-yield strain for producing riboflavin and application of the bacillus high-yield strain, and belongs to the technical field of microbial fermentation. The bacillus strain is named as VB2-M-230602-66, the preservation unit is China Center for Type Culture Collection, the preservation date is December 1, 2023, and the preservation number is CCTCC NO: M20232421; according to the invention, the strain VB2-M-230602-66 with stable character is obtained by adopting physical mutagenesis separation and combining with shake flask screening of tolerance dose of a resistance marker, riboflavin can be produced through liquid fermentation, and the yield is stable; the bacterial strain has the biological characteristics that the bacterial strain is gram-positive bacteria through gram staining, the bacteria are cultured at 37 DEG C for 18 hours, the thalli are rod-shaped, 0.5-0.8 mu m * 2.0-5.4 mu m and are arranged in a single or paired manner, and bacterial colonies cultured on a solid culture medium are pale yellow, nearly circular, wet in surface, opaque and irregular in edge; the bacillus strain VB2-M-230602-66 provided by the invention is suitable for fermentation production of riboflavin (vitamin B2), has stable production performance, can obtain greater economic benefits, and is worthy of popularization.

The invention discloses a method for producing a fish and shrimp pond water quality conditioner by using hermetia illucens larvae. The clean and sanitary feed raw materials with a specific ratio are used as the black soldier fly larva culture material, and the culture material is not only suitable for growth of the black soldier fly larvae, but also suitable for water quality conditioning of fish and shrimp ponds after transformation. The culture material is converted into the fish and shrimp pond water quality conditioner by utilizing the biological characteristics of hermetia illucens larvae. The water quality conditioner can effectively reduce ammonia nitrogen, nitrite and harmful pathogenic bacteria of the fish and shrimp pond, treat water quality pollution of the fish and shrimp pond, stabilize water quality and improve the fish and shrimp culture success rate.

The invention discloses primers and a method for detecting Corynebacterium bovis and application of the primers and the method in detection of pathogenic bacteria of immunodeficient mice. The primers comprise an upstream primer and a downstream primer aiming at 16S rRNA (ribosomal Ribonucleic Acid) genes of the Corynebacterium bovis. The invention establishes a qPCR molecular detection method for the pathogenic bacteria Corynebacterium bovis of the immunodeficient mice, and the qPCR molecular detection method has the advantages of strong specificity, high sensitivity, high detection efficiency and the like, and can quickly and accurately detect the Corynebacterium bovis in the immunodeficient mice and the environment. The establishment of the detection method is beneficial to timely discovery and control of the bacterium, and has important significance for guaranteeing the environmental safety of personnel and the health of experimental animals. In future experimental animal quality control and related scientific research work, the qPCR detection method is expected to be widely applied, and powerful technical support is provided for further deep research on biological characteristics and pathogenic mechanisms of corynebacterium bovis.

The invention discloses a polygonatum cyrtonema high-yield cultivation method based on dynamic ridge expansion and ecological shading, and belongs to the technical field of traditional Chinese medicinal material cultivation. The method comprises the following steps: selecting high-quality seed stems; the seedlings are placed in ridges in a high-density single-row mode, and bud heads face the two sides alternately during placement; sowing high-stem crops at ridge edges in the early growth stage and in furrows in the later growth stage so as to ecologically shade and improve the soil structure; fine weeding is carried out by adopting a partitioning strategy; and a dynamic management mode of'year-by-year ridge expansion and fertilization 'is adopted. Compared with a traditional fixed ridge mode, the yield per mu can be remarkably increased by 27% or above, the occurrence rate of plant diseases and insect pests is reduced, meanwhile, the weeding labor cost is greatly reduced, and the soil structure and fertility are effectively improved. According to the method, the biological characteristics of the polygonatum cyrtonema are accurately matched, the problems of low utilization rate of fixed ridge cultivation organic fertilizer, high weeding cost, later soil hardening, serious root rot and high shading cost are effectively solved, the yield and commodity quality of the polygonatum cyrtonema are remarkably improved, and the method is suitable for large-scale popularization and application.

The invention discloses a pseudomonas aeruginosa bacteriophage vBPaePpha0325 and an application of the pseudomonas aeruginosa bacteriophage vBPaePpha0325. The pseudomonas aeruginosa phage vBPaePpha0325 is classified and named as pseudomonas aeruginosa phage, and is preserved in the Guangdong Microbiological Culture Collection Center on December 29, 2025, the preservation number is GDMCC NO: 67562-B1, and the preservation address is Institute of Microbiology, Academy of Sciences, Guangdong Province. The bacteriophage vBPaePpha0325 shows remarkable splitting activity on pseudomonas aeruginosa, can efficiently kill and split host bacteria, and has the biological characteristics of short incubation period and high splitting quantity. The bacteriophage has strong adaptability to environmental conditions, and shows good temperature and acid-base tolerance. Genome analysis proves that the strain does not contain virulence genes and antibiotic resistance genes, has good biological safety, and shows application potential as an antibacterial preparation.

This invention discloses a strain of Salmonella choleraesuis phage SCP512 and its applications, belonging to the field of microbial technology. Salmonella choleraesuis phage SCP512 is deposited at the China General Microbiological Culture Collection Center (CGMCC) with accession number CGMCC No. 47021, dated February 4, 2026. It belongs to the family Myocaudae within the class Caudata. This phage SCP512 possesses multivalent lytic characteristics, excellent biological properties and environmental adaptability, and can disrupt pathogen biofilm formation. It addresses the technical problems of existing phages, such as limited lytic spectrum, insufficient coverage of common foodborne pathogens, weak biofilm removal ability, and limited application potential in practical food matrices.

The embodiment of the invention provides cleaning equipment and a control method thereof. The cleaning device comprises an ultraviolet lamp source, a camera and a processing assembly. And the outer lamp source is used for emitting ultraviolet light to the stains so as to excite the fluorescence reaction of the stains. The camera is used for acquiring a fluorescence picture after the stain is subjected to fluorescence excitation reaction. And the camera is also used for acquiring a color picture of the stain. In this way, the color picture can obtain two-dimensional information such as the color, the texture and the range of the stains. Based on the biological properties of urine, the ultraviolet lamp source emits ultraviolet light to urine stains to excite fluorescence reaction of the urine, and the camera obtains fluorescence pictures of the stains. And the fluorescent picture can acquire information about whether the stain has fluorescence or not. Therefore, the processing component can determine whether the type of the liquid is urine or not through the color picture and the fluorescence picture.

The invention relates to the field of insect prevention and control, in particular to a high-toxicity metarhizium anisopliae strain IPPMA362 resistant to high temperature and ultraviolet stress and application thereof. The invention aims to screen excellent metarhizium anisopliae strains with high toxicity to bemisia tabaci. Through indoor biological activity determination, the lethal ability of the target strain on the bemisia tabaci nymphs is determined; further, key biological characteristics such as sporulation capability, spore germination rate and ultraviolet resistance of the strain are systematically evaluated, so that the application potential of the strain is judged; and the optimized strain is accurately identified through a molecular biology means, so that a foundation is laid for subsequent strain registration, patent protection and product development.

The invention relates to a corn variety five-level four-dimensional evaluation method and application, the method comprises a five-level index evaluation system of basic agronomic traits, stress resistance performance, yield composition, quality characteristics and industrialization potential, and data acquisition and analysis are carried out through four dimensions of scientific quantification, production adaptability, industrial application and economic and social values. According to the method, traditional empirical evaluation is converted into a quantifiable data model through hierarchical weighting and multi-dimensional data fusion, subjective deviation is overcome, and whole-industry-chain closed-loop evaluation of the corn varieties from biological characteristics to market values is achieved. According to the method, an efficient and scientific decision-making tool is provided for variety certification, variety breeding, farmer seed selection and enterprise investment, and the transformation of the corn industry from yield to quality and benefit is promoted.

The application discloses a kind of multi-dimensional dynamic model under the evaluation method of soil salinization to cultivated land productivity, it is related to the field technical field of agricultural resources and environment, and the multi-source data set of fusing remote sensing, ground monitoring, meteorological and farmer management data is first constructed in the scheme, and the minimum data set of soil physical, chemical, biological properties is screened after fusion preprocessing;Soil quality index (SQI) and cultivated land productivity index (CPI) are calculated again;Subsequently, the multi-dimensional dynamic evaluation model containing key salinization index screening, effect quantification, mechanism model and crop sub-model is constructed;Finally, the productivity influence dynamic update is realized in combination with real-time data of Internet of Things, and the optimal improvement technology mode is simulated and screened by structural equation model simulation management scene. The method is comprehensive in data coverage, accurate in evaluation, dynamic in model and targeted, can reveal the influence mechanism of salinization on cultivated land productivity, provide practical decision support, and help efficient and sustainable use of saline-alkali soil.

The invention discloses sinorhizobium meliloti ASZJHZ25-4 with functions of efficiently promoting growth and inhibiting aspergillus flavus and application of the sinorhizobium meliloti ASZJHZ25-4, and the preservation number of the sinorhizobium meliloti ASZJHZ25-4 is CCTCC M 2026230. According to the invention, the integration of two functions of generating a characteristic antibacterial volatile matter of 2-methylbutyric acid and efficiently symbiotic nitrogen fixation on a single strain is realized in the sinorhizobium meliloti for the first time. The 2-methylbutyric acid volatile matter released by the strain can accurately down-regulate expression of toxin synthesis key genes and spore development core genes in aspergillus flavus, so that efficient bacteriostasis is realized on the molecular level. Through one-time inoculation, the dual purposes of growth promotion and nitrogen fixation and source bacteriostasis can be synchronously achieved at the rhizosphere ecological niche of the peanuts. Especially aiming at the biological characteristics of overground flowering and underground fruiting of peanuts, a lasting biological fumigation protection layer is formed in a soil microenvironment in a legume development critical period.

The application provides a fusion protein PA-G which fuses Ig dominant binding domains of protein A and protein G, and the amino acid sequence of the fusion protein PA-G is as shown in SEQ ID NO. 1. The fusion protein PA-G disclosed by the application has the immunoglobulin binding capacity, has the larger biological characteristic potential than protein A and protein G, has the better affinity and faster binding efficiency for different species and subtypes of immunoglobulins, and through acid and alkali resistance research experiments, it is found that the most important thing of the fusion protein PA-G is that the pH tolerance is wider, and the application prospect and application range are wider.

The present application relates to a kind of yunnan ganoderma strain L4741 and its cultivation method, belong to the field of microbial technology.The yunnan ganoderma strain L4741 has been preserved in Guangdong Provincial Microbial Culture Collection Center on December 27, 2021, and the preservation number is GDMCC No:62108.Through collecting and separating wild ganoderma strain L4741 and combining morphological and DNA barcoding technology to determine its taxonomic status, strain culture, biological characteristics and artificial domestication cultivation are carried out, and mature fruiting bodies are obtained after bag material covering soil cultivation.The yunnan ganoderma strain L4741 of the present application has excellent agronomic traits, high and stable yield, bag yield is 61.6g / bag, equivalent to 308kg per mu.Moreover, the content of active substance is higher than that of widely cultivated ganoderma lucidum, the mushroom is neat and has good stress resistance, the genetic traits are stable, and it is easy to popularize and apply.

The invention discloses a sinorhizobium fredii strain capable of promoting growth and inhibiting aspergillus flavus and application of the sinorhizobium fredii strain. The sinorhizobium fredii strain is classified and named as sinorhizobium fredii, and the preservation number of the sinorhizobium fredii strain is CCTCC (China Center for Type Culture Collection) M 20253054. According to the invention, the dual functions of generating a specific bacteriostatic volatile matter 2-nonanol and efficiently symbiotic nitrogen fixation are integrated in the sinorhizobium freudenreanum for the first time. 2-nonanol released by the strain can accurately down-regulate expression of toxin synthesis key genes and spore development core genes in aspergillus flavus, so that efficient bacteriostasis is realized on the molecular level. Through one-time inoculation, the strain can synchronously achieve the dual purposes of growth promotion and nitrogen fixation and source bacteriostasis at the rhizosphere ecological niche of the peanuts. Especially aiming at the biological characteristics of overground flowering and underground fruiting of peanuts, a lasting biological fumigation protection layer can be formed in a soil microenvironment in a legume development critical period.

The invention provides a gel aerobic particle based on sludge immobilization and a preparation method and application thereof, and belongs to the field of sewage treatment.The method comprises the steps that 1, sEPS powder is evenly dispersed in a sodium alginate solution, and composite gel is obtained; 2, filtering and centrifuging the activated sludge in the aerobic tank, and removing supernate to obtain concentrated bacterial liquid; and 3, adding the concentrated bacterial liquid into the composite gel, uniformly mixing, dripping into a cross-linking solution, and curing to obtain the gel aerobic particles. According to the gel aerobic particle based on sludge immobilization, the composite gel is prepared from the structural extracellular polymeric substance in the activated sludge and the sodium alginate, and the concentrated activated sludge is immobilized by using the multivalent metal ion cross-linking agent; gel aerobic particles with chemical components, mechanical strength and biological properties similar to those of natural aerobic particles are prepared, and rapid granulation of sludge and rapid starting operation of a granular system are achieved.

A method, computer program product, and computer system for assessing carbon sequestration contribution of a nature-based asset located in a water environment are provided. The method includes obtaining a meta descriptor of the nature-based asset and a meta descriptor of a region of the water environment in which the asset is located; mapping a size of the nature-based asset; accessing data of a monitored physical property of the asset in the water environment based on the meta descriptor of the asset; accessing data of a monitored carbon concentration in the region of the water environment based on the meta descriptor of the region; accessing data of monitored physical, chemical, and biological properties of the water environment based on the meta descriptor of the region; and applying a model to the accessed data to assign a carbon sequestration contribution per unit of measurement of the nature-based asset.

The application discloses a kind of northern Shaanxi white cashmere goat muscle satellite cell separation and purification method, the present application uses northern Shaanxi white cashmere goat fetus dorsal longest muscle tissue as test material, by aseptic pretreatment, tissue block inversion adherent culture, primary subculture culture Combination of compound technology of hierarchical differential adherent purification, stably obtain the 5th generation muscle satellite cell.The present application optimizes and adapts culture system and purification process, overcomes the defects of low cell yield, serious interference of mixed cells, activity and poor purity of traditional preparation method.At the same time, the present application also adopts RT-PCR molecular identification and immunofluorescence staining combined with multi-level verification method, from gene and protein level Bidirectional verification cell specificity and differentiation potential, accurately determine the biological properties of cell.The present application process is simple, good stability and repeatability, can efficiently prepare northern Shaanxi white cashmere goat muscle satellite cell, provides important technical support for cashmere goat germplasm resource conservation, muscle development mechanism and muscle regeneration related research.

This invention provides a highly active surface-modifying agent for saline-alkali land and its application, belonging to the field of saline-alkali land improvement technology. Under ultrasonic conditions, a sulfur source is pre-loaded into biomass. Under the action of sulfate free radicals, a hydrothermal reaction process etches the surface of the hydrothermal carbon, increasing the specific surface area and porosity. Simultaneously, the broken C-C bonds provide active sites for sulfur doping. At the same time, alginate and Fe... 3+ Cross-linking forms a hydrogel network that encapsulates hydrothermal carbon, enhancing sulfur stability, reducing direct contact between the material and soil, protecting the material's functional groups, achieving efficient ion exchange within the membrane, and increasing the material's interaction time. This invention, through a triple mechanism of "exchange desalination – soil aggregation – nutrient enhancement," can improve the physical, chemical, and biological properties of saline-alkali soils, promote crop growth, reduce soil heavy metal content, enhance carbon sequestration, reduce the bioavailability and toxicity of pollutants, and restore ecosystem structure and function.

The present application relates to a Klebsiella pneumoniae bacteriophage, a bacteriophage composition thereof and application thereof, and belongs to the field of microorganisms. The present application provides a lytic bacteriophage Kp_WF01 infecting Klebsiella pneumoniae, and biological property research, morphological observation and whole-genome phylogenetic analysis are performed on the bacteriophage, and it is determined that the bacteriophage Kp_WF01 is a new species of Caudoviricetes Class Autographivirales Order Autotranscriptaviridae Family Przondovirus Genus. The in-vivo treatment effect and safety of the bacteriophage Kp_WF01 are evaluated by using a mouse model infected with CRKP, and the results show that the bacteriophage Kp_WF01 can rescue the CRKP-infected mouse, can be used as an effective therapeutic preparation against CRKP infection, and the treatment effect of the bacteriophage Kp_WF01 is better than that of imipenem.

The invention discloses a rhizobium mesonii strain APHNZY-24-4 which has the functions of promoting peanut growth and inhibiting aspergillus flavus, and the preservation number of the rhizobium mesonii strain APHNZY-24-4 is CCTCC (China Center for Type Culture Collection) M 2026228. According to the invention, integration of two functions of generating a specific bacteriostatic volatile matter, namely 3-methylbutyric acid, and efficient symbiotic nitrogen fixation on a single strain is realized in the rhizobium japonicum for the first time. 3-methylbutyric acid released by the strain can accurately down-regulate expression of toxin synthesis key genes and spore development core genes in aspergillus flavus, so that efficient bacteriostasis is realized on the molecular level. Through one-time inoculation, the strain can synchronously achieve the dual purposes of growth promotion and nitrogen fixation and source bacteriostasis at the rhizosphere ecological niche of the peanuts. Especially aiming at the biological characteristics of overground flowering and underground fruiting of peanuts, a lasting biological fumigation protection layer can be formed in a soil microenvironment in a legume development critical period.

This invention belongs to the field of biomedical materials technology, and discloses a one-step chitosan-grafted iohexol self-illuminating microsphere, its preparation method, and its applications. The microsphere uses chitosan, a natural biocompatible material, as the carrier framework, iohexol as the self-illuminating functional component, and genipin, a natural extract, as the cross-linking agent. A one-step grafting and cross-linking curing process is used to form self-illuminating microspheres with uniform particle size and stable structure. These microspheres exhibit clear imaging under X-rays and also possess good biocompatibility, biodegradability, and sustained-release properties, making them widely applicable in medical fields such as tumor embolization therapy and tissue engineering tracing, achieving integrated diagnosis and treatment. The preparation process of this invention is simplified, requiring no multi-step reactions, with mild control conditions, and is easy for industrial production, solving the problems of complex preparation, poor biocompatibility, and imbalance between imaging and biological properties in traditional self-illuminating materials.

The present disclosure provides tissue scaffolds and hydrogels as well as methods of making and using the same. Also provided are tissue scaffolds with improved biological properties and methods of utilizing said tissue scaffolds for the treatment of wounds.

The invention belongs to the technical field of microorganisms, and particularly relates to a P.megatherium PM-MZM strain and application thereof. According to the invention, a strain of P.megatherium PM-MZM is separated from excrement of healthy Hu sheep, and biological preservation is carried out on the P.megatherium PM-MZM. A biological characteristic research result shows that the strain has relatively strong biofilm forming capability, relatively high self-agglutination capability and relatively good acid-resistant and cholate-resistant capability. The activity can still be maintained in a high-temperature and high-concentration cadmium environment. The strain has no hemolytic activity, is sensitive to most antibiotics, and has good safety. The P.megatherium PM-MZM provided by the invention is stable in genome structure, has relatively strong carbohydrate degradation utilization and nutrition uptake capabilities, contains a large number of unique functional genes, effectively reduces intestinal injury under a cadmium pollution condition, and improves the intestinal health of animals. According to the invention, the resource library of the Prussella strain is enriched, and an important support is provided for the development and application of intestinal probiotic resources.