The invention discloses a thermoelectric power station automatic control system based on artificial intelligence. It includes dispersible control system, virtual DCS simulation system, program controlling system, monitoring information system and malfunction diagnosing and optimizing controlling system; the dispersible control system is connected with the virtual DCS simulation system and program controlling system; the program controlling system process the operating parameters of every machine group transmitted by dispersible control system, and at the same time transmits data to monitoring information system to display, then transmits malfunction diagnosing and optimizing controlling system to have equipment state monitoring, malfunction diagnosing and forewarns. The invention gathers automatic control, optimizing operation, security monitoring and malfunction diagnosing and forecast. It can improves the automated management level of the thermoelectric power station operation, and enhances enterprises' benefit. It has great economic and applied value in the producing process automatic control of the thermoelectric power station.