The application relates to the technical field of
high polymer materials, in particular to a
hyaluronic acid-collagen composite gel for facial filling and a preparation method thereof, which is physically mixed from a collagen solution and a
hyaluronic acid solution, wherein the volume of the
hyaluronic acid solution is three times that of the collagen solution, the concentration of the hyaluronic acid solution is mixed from
sodium hyaluronate and a composite buffer, the collagen solution is mixed from
bovine collagen and the composite buffer, the molecular weight of the
bovine collagen is 300-400 kDa, and the composite buffer contains
lidocaine hydrochloride and a
phosphate. The hyaluronic acid-collagen composite gel for facial filling and the preparation method thereof improve the material properties of collagen, enhance the anti-deformation ability and
viscosity of the material, make the material better fit the
facial profile and dynamic changes, reduce the deformation and displacement risk after injection, and help to improve the
facial appearance and
skin state and promote the repair and regeneration of the
skin.