20 results about "Hyperthermic perfusion" patented technology

The present application relates to the technical field of medical devices, in particular to a 3D printing vaginal hot perfusion aid, comprising an integrally formed medicine guide rod and wing, the medicine guide rod is columnar as a whole, an axial through hole is arranged in the medicine guide rod for penetrating a catheter, and the wing is arranged on the sidewall of the medicine guide rod. The design solves the problem that when a patient is treated with hot therapy, medicine needs to be injected into the patient's vagina, and the medicine injected into the vagina is prone to flowing out. The present application has a simple structure and is convenient for wide promotion and application.

1. The name of the design product: body cavity hot perfusion therapy machine. 2. The use of the design product: for hot perfusion therapy in human body. 3. The design points of the design product: the shape of the product as a whole. 4. The picture or photo that best indicates the design points: perspective view 1.

The invention discloses a sealing negative pressure protection device for abdominal cavity hyperthermic perfusion chemotherapy in laparotomy, and belongs to the technical field of medical instruments, the sealing negative pressure protection device comprises a protection cover body, the protection cover body is of a three-layer structure and sequentially comprises a porous breathable layer, a middle adsorption layer and a sealing supporting layer from inside to outside, and a circle of medical pressure-sensitive adhesive is arranged on the edge of the inner layer of the protection cover body; a negative pressure connector is arranged at the top of the protective cover body and used for being connected with external negative pressure equipment, two hanging rods are perpendicularly fixed to the inner layer of the protective cover body, telescopic supporting structures are fixed to the bottom ends of the two hanging rods, and a plurality of liquid inlet holes and liquid outlet holes are further formed in the protective cover body. The supporting assembly is integrated on the inner side of the protective cover body, and the problems that the compatibility of the surgical retractor and a sealing rubber strip on the edge of the protective cover body is poor, and gaps are likely to be generated are solved; by arranging the negative pressure connector and the middle adsorption layer, dual treatment of aerosol is achieved, and the occupational exposure risk of medical staff is reduced.

The invention discloses an abdominal cavity circulation hyperthermia perfusion device for tumor treatment, and relates to the technical field of tumor treatment, the abdominal cavity circulation hyperthermia perfusion device comprises a bottom plate, the upper end of the bottom plate is provided with two supporting plates, a supporting shaft is rotatably connected between the supporting plates, the surface of the supporting shaft is rotatably connected with two connecting sleeves, and the two connecting sleeves are jointly provided with a lying plate; an adjusting assembly is installed at the lower end of the lying plate, leg fixing assemblies are installed on the front portion and the rear portion of the upper end of the lying plate, an upper limb fixing belt is adjustably installed at the upper end of the bottom plate on one sides of the leg fixing assemblies, and circulating hot perfusion equipment is placed on one side of the bottom plate and provided with a pipe inserting opening. A patient lies on a lying plate, a driving motor in the adjusting assembly is controlled to drive a meshing gear to rotate, the meshing gear drives the lying plate to swing around a supporting shaft through a semi-annular rack, the angle of the lying plate is adjusted, the patient can be in a flat lying and side turning state, and medical workers do not need to conduct auxiliary adjustment.

This invention discloses a hyperthermic perfusion device, relating to the field of medical devices. It provides a hyperthermic perfusion device with a simpler tubing system, facilitating shorter preparation time for hyperthermic perfusion chemotherapy. The hyperthermic perfusion device includes a main unit and a liquid circulator; the liquid circulator includes a rigid liquid container, a suction tube, a return container, an output tube, a return tube, and two dispensing pumps; the dispensing pumps are vertically positioned at the upper end of the rigid liquid container, and include an inlet check valve, a drain check valve, a collar, and a liquid aspirator with a piston rod. The inlet and drain check valves communicate with the internal space of the liquid aspirator, and the collar is connected to the piston rod; the suction tube is connected to both inlet check valves and extends to the lower part of the rigid liquid container; the return container is located at the upper end of the rigid liquid container and has a filter screen; the output tube is connected to the rigid liquid container and connected to the two drain check valves via tubing; the return tube is connected to the return container; the main unit can heat the rigid liquid container and drive the dispensing pumps.

The invention discloses a pressurizing flushing device for hyperthermic intraperitoneal perfusion chemotherapy, and relates to the technical field of medical instruments. Comprising a puncture catheter and a multidirectional flow guide nozzle, the puncture catheter comprises a catheter body, multiple sets of supporting cavities are formed in the catheter body in the length direction, the supporting cavities are communicated through second air inlet channels, and the supporting cavities are of an arc-shaped structure; the end part of the guide pipe body is connected with a multidirectional flow guide nozzle; one end of the nozzle main body is connected with a drainage guide pipe; the drainage catheter is used for connecting a chemotherapy pump machine; the nozzle body comprises a sprayer and a connecting pipe. The other end of the connecting pipe is connected with the drainage catheter; a plurality of through holes are formed in the spray head; and a rotor is rotationally arranged in the connecting pipe. The catheter is prevented from being bent and collapsed under the action of external force such as extrusion of visceral organs in the abdominal cavity and body position change, and it is ensured that a liquid medicine conveying channel is smooth; in addition, the contact uniformity of the liquid medicine and the abdominal cavity wall, especially the peritoneal micro transfer focus, is obviously improved.

The application discloses a kind of abdominal cavity hyperthermic perfusion chemotherapy device in the technical field of medical devices, including frame, the top in frame is provided with the article track for hanging medicine, frame is equipped with delivery pump, delivery pump liquid inlet end and liquid outlet end are equipped with connecting pipe, and delivery pump is respectively communicated with needle holder and rotating disc rotation connection by connecting pipe, and rotating connection has take-up reel, take-up reel is communicated and is wound with output pipe, rotating connection has water tank in take-up reel, heating element is fixedly connected in water tank, transmission screw is fixedly connected in take-up reel end, transmission screw is screw-connected with slide base, slide base is slidably connected with slide rod, water tank outside is fixedly connected with support, support is fixedly connected with resistor, resistor is slidably connected with slide base, and adjusting piece is fixedly connected with slide base, frame is equipped with recovery tank and liquid guide frame;It can be automatically adjusted the temperature of liquid medicine according to the length of use pipeline, ensure that the temperature of liquid medicine into human body can eliminate pathogenic bacteria, also can avoid causing scald to human body.

The invention relates to the technical field of heat energy input treatment, in particular to an intelligent integrated intraperitoneal hyperthermic perfusion full-process management method which comprises the following steps: acquiring pressure intensity data, comparing a propelling trend to identify an abnormal path, calling temperature reading to screen a non-synchronous cooling path, switching a liquid injection path to propel cold liquid, and monitoring cavity pressure fluctuation to identify a response lagging path. And extracting an action sequence to obtain a multi-path execution list. According to the method, the path with abnormal liquid propulsion and uneven heat exchange can be recognized through combined collection and trend analysis of pressure and temperature data, path switching is combined with pressure control to guide the liquid injection direction, channel retardation and residual heat retention can be dealt with, whether channel response is lagged or not can be judged through periodic correlation of cavity pressure reading and liquid injection action, and the accuracy of channel response is improved. An operation instruction and a path behavior sequence are linked to construct a task execution chain, and a data-driven identification judgment, path screening and control closed loop is formed in path propulsion, so that the coordination and continuity of a perfusion process are enhanced, and the dependence on artificial experience is reduced.

The local directional hyperthermic perfusion chemotherapy device comprises a liquid medicine tube, a heating tube, a liquid medicine release body and a drainage tube, the liquid medicine release body comprises a heating cavity and a release cavity which are arranged in an overlapped mode, a permeable membrane is arranged on the release face of the release cavity, one end of the liquid medicine tube is communicated with an external liquid medicine bag, and the other end of the liquid medicine tube is communicated with the release cavity of the liquid medicine release body; the heating pipe comprises an input section heating pipe and an output section heating pipe, the input section heating pipe and the output section heating pipe wrap the liquid medicine pipe in the middle, the input section heating pipe, the liquid medicine releaser heating cavity and the output section heating pipe are sequentially communicated to form a heating channel, the heating channel is communicated with an external heat supply device, and a heating medium flows in the heating channel; the drainage tube is used for draining the liquid medicine in the abdominal cavity out of the abdominal cavity; according to the utility model, the local focus of the abdominal cavity is directionally perfused, the whole abdominal cavity is prevented from being filled with liquid medicine, the toxic effect on normal cell tissues in the abdominal cavity is small, the occurrence of chemotherapy complications is reduced, and the chemotherapy quality is improved.

The invention discloses an automatic flow regulator for an abdominal cavity hyperthermic perfusion chemotherapy water outlet pipe, and relates to the technical field of chemotherapy equipment. The automatic flow regulator comprises a shell, a water outlet pipe containing groove is formed in the middle of the shell, a hinge is installed at an opening in one side of the water outlet pipe containing groove, the hinge is hinged to one end of a cover plate, and a fixing button is installed at the other end of the cover plate; the upper surface of the shell is provided with a display screen and keys, and the display screen and the keys are electrically connected with the controller; an adjustment execution assembly and a flow detection unit are further installed in the shell. The adjustment execution assembly and the flow detection unit are both electrically connected with the controller. According to the automatic flow regulator for the water outlet pipe for hyperthermic intraperitoneal perfusion chemotherapy, manual operation is replaced, automatic and real-time regulation of flow is achieved, and the regulation response time is short; the flow control precision is high, the in-vivo liquid amount is stabilized, and the curative effect stability of intraperitoneal hyperthermic perfusion chemotherapy is improved; the adaptability is good, and the medical risk is reduced through the safety alarm function; and existing perfusion equipment is compatible, and clinical popularization is facilitated.

The puncture catheter is characterized in that the puncture catheter comprises a catheter body, a plurality of sets of supporting cavities are sequentially formed in the catheter body in the length direction, the supporting cavities are sequentially communicated through second air inlet channels, and each supporting cavity is of an arc-shaped structure; the catheter body is further provided with a first air inlet channel, the end of the first air inlet channel is connected with a blocking air bag, and the blocking air bag is arranged close to the end of the catheter body. Through the arrangement, gas is injected into the second gas inlet channel, so that each group of arc-shaped inner cavities are filled with the gas, and the structural strength and the extrusion resistance of the catheter body are effectively enhanced by utilizing the bending resistance characteristic of the arc-shaped structures and the supporting force after the gas is filled; the catheter is prevented from being bent and collapsed under the action of external force such as extrusion of visceral organs in the abdominal cavity, body position change and the like, a liquid medicine conveying channel is ensured to be smooth, and smooth proceeding of hyperthermic perfusion chemotherapy in the abdominal cavity is guaranteed.

This invention discloses a multi-directional flow nozzle for intraperitoneal hyperthermic perfusion chemotherapy, belonging to the field of medical device technology. It includes a nozzle body, one end of which is connected to a drainage conduit for connecting to a chemotherapy pump. The nozzle body includes a nozzle head and a connecting tube. One end of the connecting tube is fixedly connected to the nozzle head, and the other end is connected to the drainage conduit. Multiple through holes are evenly distributed on the nozzle head. A rotor is rotatably mounted inside the connecting tube. The connecting tube includes a Venturi tube segment and a connecting section. The rotor is positioned within the throat of the Venturi tube segment. A variable-diameter channel is located at the center of the rotor, and multiple guide vanes are evenly distributed circumferentially along a fixed support rod at the center of the variable-diameter channel. Water flow causes the rotor to rotate, inducing a vortex field in the intraperitoneal medication through the guide vanes. This invention forms a dynamic circulation under pressure, significantly improving the uniformity of contact between the medication and the peritoneal wall, especially small peritoneal metastases. The reaction force of the water flow drives the nozzle head to rotate or form a vortex, greatly improving the therapeutic effect of intraperitoneal hyperthermic perfusion chemotherapy.

The invention belongs to the technical field of medical equipment, and particularly relates to an abdominal cavity hyperthermia perfusion pipeline dredging device which comprises a perfusion liquid medicine box, a flushing liquid box is fixedly connected to the upper surface of the perfusion liquid medicine box, a first heating pipe is fixedly connected to the inner bottom wall of the perfusion liquid medicine box, and a second heating pipe is fixedly embedded in the left side face of the flushing liquid box. A first temperature monitoring sensor is fixedly embedded in the front face of the liquid medicine filling box. Through the arrangement of the intraperitoneal hyperthermia perfusion tube, the flow sensor, the pressure sensor, the ultrasonic detection assembly, the central controller and the early warning alarm, flow and pressure data of perfusate in a pipeline can be collected in real time, and the position, the size and the form of blockages in the pipeline can be detected in a high-frequency ultrasonic mode; multi-sensor cooperative monitoring and high-frequency ultrasonic detection of the intraperitoneal hyperthermic infusion tube are achieved, suspected blockage signals can be captured in advance, timely alarm early warning and dredging treatment are carried out, treatment interruption caused by blockage deterioration is avoided, and the treatment effect is improved.

A circulation pipeline system used for hyperthermic perfusion chemotherapy comprises a perfusion fluid power pipeline, which is provided with a fluid injection end, a fluid outlet end and a fluid return end; the crossed access body pipeline comprises a first pipeline, a second pipeline, a third pipeline and a fourth pipeline, the first pipeline and the second pipeline are provided with opposite access ends and connecting ends, the connecting end of the first pipeline is communicated with the liquid return end, and the connecting end of the second pipeline is communicated with the liquid outlet end; the connecting-in end of the first pipeline and the connecting-in end of the second pipeline are used for being connected into a patient body cavity, the third pipeline is communicated with the fourth pipeline in a crossed mode, the two ends of the third pipeline are communicated with the first pipeline and the second pipeline respectively, and the two ends of the fourth pipeline are communicated with the first pipeline and the second pipeline respectively. According to the device, sediments on the pipe wall can be stripped through impact of in-out body reverse fluid, deposition and blockage are avoided, meanwhile, by means of the flow dividing, cross mixing and reverse rotational flow effects generated by water flow, a medicament can be rapidly and evenly spread over the whole water body, and continuity of medicament perfusion is guaranteed.

According to the hyperthermia perfusion treatment device provided by the invention, the human body connecting unit is provided with the special human body connecting interface and can be accurately and stably connected with the human body, so that a reliable passage is formed between the whole treatment device and the human body, and a basic guarantee is provided for subsequent operations such as liquid medicine leading-out and medicine perfusion. The body fluid outlet pipe, the medicine injection unit, the temperature control heating unit and the body fluid inlet pipe are connected in sequence and are matched with the human body connecting unit to form a complete liquid medicine circulating channel; liquid medicine in a human body is led out through the body liquid outlet pipe, medicine is injected through the medicine injection unit, then the temperature control heating unit controls the temperature of the liquid medicine containing the medicine, finally the treated liquid medicine is conveyed back to the human body again through the body liquid inlet pipe, the whole process is smooth, and efficient treatment can be achieved easily. Through the synergistic effect of all the units, precise infusion of the medicine and precise control over the temperature can be achieved, the medicine can better play a role, and the treatment effect on the diseased region is enhanced.

The utility model relates to a carbon dioxide chemotherapeutic drug aerosol generating device which comprises a drug delivery pipeline, a drug atomizer and an abdominal cavity, one end of the drug delivery pipeline is connected with the drug atomizer, and the other end of the drug delivery pipeline is connected with the abdominal cavity through a first drug delivery branch and a second drug delivery branch; and the second dosing branch is connected with a carbon dioxide pneumoperitoneum machine through a bypass pipeline. The novel carbon dioxide chemotherapy drug aerosol generating device can provide carbon dioxide chemotherapy drug aerosol with smaller mist particles and uniform distribution, a small amount of anti-cancer drugs can be more effectively conveyed to cancer cells, the dosage of the chemotherapy drugs is only 10-30% of that of traditional intraperitoneal hyperthermic perfusion chemotherapy (HIPEC), the aerosol is high in tissue penetrating power, pharmacokinetics can be improved, and the effect of treating cancer cells is achieved. The dosage of chemotherapeutic drugs is greatly reduced, toxic and side effects are reduced, the treatment cost is reduced, and high efficiency, convenience and safety are achieved.

The invention discloses a bone cement type intramedullary nail device capable of being used for hyperthermic perfusion chemotherapy. The bone cement type intramedullary nail device comprises a main nail, a hyperthermic perfusion injector, a bone cement injector and an aspirator. The main nail is suitable for being implanted into a lesion medullary cavity through a guide needle, a through hollow main nail medullary core is formed in the main nail in the axial direction, an injection opening communicated with the main nail medullary core is formed in the near end of the main nail, and the main nail is suitable for being connected with a hyperthermia perfusion syringe or a bone cement syringe so that chemotherapeutic drugs or bone cement can be injected into the main nail medullary core. A leaking hole communicated with the main nail medullary core is formed in the far end of the main nail, so that chemotherapeutic drugs or bone cement flows into a lesion medullary cavity; and the aspirator is communicated with the diseased medullary cavity through the water outlet screw so as to suck out the chemotherapeutics in the diseased medullary cavity. The bone nail has remarkable beneficial effects in the aspects of mechanical stability, chemotherapy drug hyperthermic perfusion treatment, bone cement filling and fixation enhancement, surgical operation process simplification, main nail structure design optimization and the like, and has a wide application prospect in the field of treatment of limb long tubular bone metastatic cancer.

The invention relates to the technical field of medical apparatus and instruments, and discloses a system and method for intracavity pressure management of hyperthermic perfusion chemotherapy for abdominal tumors. Comprising a data acquisition module used for acquiring dynamic pressure data of a perfusion pump in the intraperitoneal hyperthermic perfusion chemotherapy process; the physiological data acquisition module is used for acquiring respiration data and heartbeat data of the patient; the pressure processing module is used for generating an internal organ pressure estimation value based on a pre-stored internal organ pressure estimation value model, and reducing the dynamic pressure data of the perfusion pump and the internal organ pressure estimation value to obtain reduced pressure data; the pressure analysis module is used for analyzing the pressure conditions of blood vessels and diaphragms in the abdominal cavity in combination with the respiration data, the heartbeat data and the reduced pressure data and judging whether the pressure in the abdominal cavity is abnormal or not; and the early warning module is used for generating early warning information to prompt to carry out minimally invasive and open measures when the pressure analysis module judges that the pressure in the abdominal cavity is abnormal.

This invention relates to a fixation device for an indwelling catheter used in intraperitoneal hyperthermic perfusion, comprising a fixing block, a first fixing part, a second fixing part, a shaft, a blade, and a baffle. The fixing block has a through hole connecting its upper and lower sides. The upper side of the fixing block is recessed downwards to form an arc-shaped groove for accommodating the upper part of the indwelling catheter and a connecting groove. The center of the arc-shaped groove is located on the axis of the through hole. One end of the connecting groove is connected to one end of the arc-shaped groove, and the other end is connected to the upper end of the through hole. When the upper end of the indwelling catheter is pulled upwards, the wall of the indwelling catheter pushes the baffle to rotate. The baffle drives the shaft and the blade to rotate, and the blade's cutting edge rotates towards the through hole and sweeps across the location of the through hole. Due to the adoption of the above technical solution, this invention can reduce the possibility of abdominal puncture site tearing, bleeding, and organ damage when patients attempt to remove the catheter unplannedly and forcefully.

The invention relates to the technical field of biomedical engineering, and discloses an accurate temperature control system for hyperthermic perfusion chemotherapy of abdominal tumors, which overcomes the difficulty of monitoring blind areas caused by complex anatomical structures of the abdominal cavity by constructing a patient-specific porous medium flow resistance model and a physical constraint neural network. High-precision transparent reconstruction from a sparse discrete measuring point to a global three-dimensional thermal field is realized; in cooperation with a deep reinforcement learning strategy and a generalized thermal potential energy balance function, the system can actively plan an optimal perfusion flow combination, a thermal fluid is driven to bypass visceral organs to block and accurately cover hidden focuses, and local heat accumulation and treatment cold spots are effectively eliminated; besides, a self-adaptive correction mechanism based on streamline projection endows the system with real-time sensing and self-calibration capabilities for intraoperative organ displacement, so that the robustness and safety of temperature control in a dynamic physiological environment are ensured, the treatment efficiency of hyperthermic perfusion chemotherapy is remarkably improved, and the risk of complications is reduced.