Abdominal cavity hyperthermic perfusion chemotherapy device

Abstract

The invention relates to a hyperthermic intraperitoneal perfusion chemotherapy device, which belongs to the field of chemotherapy equipment and is characterized in that a liner tube is coaxially arranged in a liquid storage tank filled with liquid medicine, the bottom end of the liner tube is closed and is integrally connected with the bottom of the liquid storage tank, and an annular gap is formed between the liner tube and the inner side wall of the liquid storage tank; a closing cylinder can be vertically matched in the annular gap in a sliding manner; the lining pipe comprises a plurality of sub-pipe sections which are coaxially connected, a pair of flashboards are horizontally and slidably mounted between the end faces of every two adjacent sub-pipe sections in a sealed mode, and the side, facing the annular gap, of each flashboard is connected with a spherical cover cap through a pushing spring; when the gate closing cylinder is axially inserted into the annular gap, all the gate plates are seamlessly spliced with one another to divide the lining pipe into a plurality of rated cavities, and a perfusion pipeline used for conveying liquid medicine into the body of a patient is connected into each rated cavity. Synchronous metering and conveying of different medicine liquid amounts can be accurately achieved, operation is easy and convenient, and possibility is provided for one-time multi-position hyperthermic perfusion chemotherapy operation.

Description

Technical Field

[0001] The present invention relates to the technical field of chemotherapy equipment, in particular to a peritoneal hyperthermic perfusion chemotherapy device. Background Art

[0002] The intraperitoneal hyperthermic chemotherapy device is a medical device used for intraperitoneal hyperthermic chemotherapy, primarily for the treatment of intraperitoneal malignancies such as gastric cancer, intestinal cancer, ovarian cancer, hepatobiliary and pancreatic cancer, and malignant mesothelioma. The device heats the perfusion fluid containing chemotherapy drugs to a certain temperature (usually 43°C) and then continuously circulates the fluid at a constant temperature into the patient's peritoneal cavity for a certain period of time (usually 60 minutes). This treatment method utilizes the synergistic sensitization and perfusion flushing effects of thermochemotherapy to effectively kill and eliminate free cancer cells and microlesions in the body cavity.

[0003] There are two main control parameters of current intraperitoneal hyperthermic chemotherapy equipment. One is temperature, which requires very precise temperature, and the error is generally required to be at least no more than 0.5℃. Clinically, the drug solution is delivered as directly as possible at a constant temperature to ensure that the drug solution reaching the peritoneal cavity is maintained within a set temperature range with a small error or even no error. The other key parameter is the control of drug volume, which is even more important than the temperature control level, because chemotherapy drugs are different from general fluid metering requirements. Not only do chemotherapy drugs require very precise dosages and have extremely high requirements for flow instruments, but they also have a special feature, that is, the measured amount itself is very small, the amount of drugs delivered is small, and the corresponding perfusion pipeline is also small. It is difficult to install flow elements such as flow meters on such perfusion pipelines. Therefore, there are many limitations in design and production, as well as inconvenience in use.

[0004] In addition, in clinical practice, the lesions are often not located in one place, and multiple hot perfusion chemotherapy is required. The current perfusion chemotherapy equipment requires multiple perfusion pipes to be led out from the internal medicine box and inserted into different parts of the patient. This requires more metering elements and opening and closing elements on the pipeline, or special fluid control devices with more comprehensive functional integration, which are more expensive. Once a failure occurs, the subsequent maintenance and replacement costs will be extremely high and more troublesome. Therefore, in some cases, a chemotherapy mechanism of fractionated perfusion of various parts has to be adopted, which greatly prolongs the chemotherapy time and increases the patient's pain.

[0005] Therefore, these existing intraperitoneal hyperthermic chemotherapy devices still have many shortcomings in the output control of the drug solution volume, and technical personnel in this field urgently need to make improvements, so as to strive to make the equipment simpler and lower the cost while taking into account both measurement accuracy and ease of operation. Summary of the Invention

[0006] In view of this, the purpose of the present invention is to provide an intraperitoneal hyperthermic perfusion chemotherapy device, which uses a simple and reliable control structure to achieve simultaneous hyperthermic perfusion of multiple parts with corresponding rated doses, with accurate dosage and simple operation.

[0007] The present invention is achieved through the following technical solutions: a peritoneal hot perfusion chemotherapy device, comprising a liquid storage tank and a medicine dispensing box connected thereto, wherein the medicine dispensing box contains hot medicine liquid for chemotherapy, an inner lining tube is coaxially provided in the liquid storage tank, the bottom end of the inner lining tube is closed and integrally connected to the bottom of the liquid storage tank, an annular gap is provided between the inner lining tube and the inner side wall of the liquid storage tank, and a closing cylinder can be vertically slidably fitted in the annular gap; the inner lining tube comprises a plurality of coaxially connected sub-tube sections, a pair of gate plates are horizontally slidably and sealedly installed between the end faces of adjacent sub-tube sections, each gate plate is connected to a spherical cap toward one side of the annular gap by a pushing spring, and the spherical cap is pushed to a position where the two oppositely arranged gate plates are separated from each other by the pushing spring in the assembled state; when the closing cylinder is axially inserted into the annular gap, all the spherical caps are squeezed toward the inner lining tube, so that after all the gate plates are seamlessly spliced with each other, the inner lining tube is divided into a plurality of rated cavities, each rated cavity is connected to a perfusion pipe for conveying medicine liquid into the patient's body.

[0008] Furthermore, the gate plate is a semicircular structure, and its arc side surface can slide out of the inner liner pipe.

[0009] Furthermore, the annular blind groove formed by the annular gap cooperates with the gap of the closing cylinder, and the inner wall of the closing cylinder has a plurality of water-passing holes that are not vertically collinear with the spherical cap, so that when the closing cylinder is inserted into the annular blind groove, the medicine liquid in the liquid storage tank can flow upward into the inner liner through the gap between the closing cylinder and the annular blind groove and the water-passing holes, and flow back to the medicine dispensing box through the overflow hole at the side wall of the top port of the inner liner, so that the medicine liquid in the inner liner can be in an overflow state.

[0010] Furthermore, a screw plug is detachably installed at the pipe mouth of the inner lining pipe, and the screw plug is connected to a medicine liquid delivery pipeline fixed at the outlet end of the medicine dispensing box, and a control valve is provided on the medicine liquid delivery pipeline.

[0011] Furthermore, the inner wall of the bottom port of the closing cylinder has a rounded corner, and the rounded corner is used for sliding contact with the spherical cover cap.

[0012] Furthermore, a perfusion hole is provided on the side wall of each sub-pipe section near the gate plate at the lower end thereof, and the perfusion hole is connected to the perfusion pipeline.

[0013] Furthermore, a central guide rod is coaxially fixed at the center of the bottom of the inner liner pipe, and a plurality of connecting rods are radially installed on the central guide rod. The connecting rods are fixedly connected to the inner wall of the sub-pipe segment so that the two adjacent sub-pipe segments are coaxially aligned, and the end faces facing each other are in sliding and extrusion contact with the corresponding gate plates to form a whole.

[0014] Furthermore, two adjacent sub-pipe sections are coaxially installed in a socket-fitted manner, and a compression spring in a compressed state is coaxially sleeved in an annular groove formed by the outer side walls of the socket-fitted sections.

[0015] Furthermore, the central guide rod is installed in situ and rotates at the center of the bottom end of the inner liner pipe, and can be fixed by axial compression of a screw plug installed at the top end of the inner liner pipe through a threaded fitting; the connecting rod is connected to the threaded section on the central guide rod through a threaded sleeve, and a stop rod is also vertically installed at the bottom end of the inner liner pipe, which passes through the connecting rod. When the central guide rod rotates and causes the two sub-pipe sections to move axially relative to each other, the corresponding connecting rod can slide axially on the stop rod.

[0016] Furthermore, a bearing bush is provided at the center of the diameter side of the gate plate, and a semicircular shell-shaped sealing gasket is embedded in the bearing bush. When the two gate plates are spliced together, the two sealing gaskets embrace the central guide rod and realize axial sliding sealing with it.

[0017] The beneficial effects of the present invention are:

[0018] The intraperitoneal hyperthermic chemotherapy device accurately controls the amount of medicine in the inner lining tube by overflow, because the inner lining tube always contains a rated amount of liquid medicine, and the amount of liquid medicine is greater than the sum of the volumes of all rated cavities. Therefore, it can ensure that after the gate plates are seamlessly connected, each rated cavity formed has a corresponding amount of liquid medicine, that is, the liquid medicine volume is calibrated by quantitatively intercepting the volume of liquid medicine, and then the amount of medicine in the corresponding rated cavity can be directly discharged to achieve the perfusion of the required amount of liquid medicine in each corresponding part. The operation is simple and easy, and does not require numerous metering components and control components. The auxiliary pipeline facilities of the equipment are streamlined, and the maintenance process is simplified. It can provide greater inclusiveness for the structural optimization design of other performance of the intraperitoneal hyperthermic chemotherapy device.

[0019] Other advantages, objects, and features of the present invention will be described in part in the following description and, in part, will be apparent to those skilled in the art upon examination of the following description or may be learned from practice of the present invention. The objects and other advantages of the present invention may be realized and obtained through the following description. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] Figure 1 A partial structural cross-sectional view of the present invention;

[0021] Figure 2 for Figure 1 A partial enlarged view of the positions of two adjacent gate plates in the structure shown in FIG;

[0022] Figure 3 for Figure 1 The cross-sectional view along the CC direction;

[0023] Figure 4 This is a schematic diagram of a specific partial structure of a closing cylinder;

[0024] Figure 5 Schematic diagram of the socket-and-spigot installation structure of two adjacent sub-pipe sections.

[0025] In the figure: liquid storage tank 1, closing cylinder 2, filling hole 201, overflow hole 202, inner lining pipe 3, gate plate 4, annular gap 5, center guide rod 6, connecting rod 7, spherical cap 8, push spring 9, compression spring 10, annular groove 11, anti-rotation rod 12, filling pipe 13, bearing 14, sealing gasket 15, water strip hole 16, threaded sleeve 17, screw plug 18, liquid medicine delivery pipe 19. DETAILED DESCRIPTION

[0026] To make the objectives, technical solutions, and advantages of the embodiments of the present invention more clear, the technical solutions of the embodiments of the present invention will be clearly and completely described below in conjunction with the accompanying drawings of the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Generally, the components of the embodiments of the present invention described and shown in the drawings herein can be arranged and designed in various different configurations.

[0027] Therefore, the following detailed description of the embodiments of the present invention provided in the accompanying drawings is not intended to limit the scope of the invention as claimed, but rather merely represents selected embodiments of the present invention. All other embodiments derived by persons of ordinary skill in the art based on the embodiments of the present invention without creative effort shall fall within the scope of protection of the present invention.

[0028] It should be noted that similar reference numerals and letters denote similar items in the following drawings, and therefore, once an item is defined in one drawing, it does not need to be further defined or explained in subsequent drawings.

[0029] See also Figure 1-3The present invention provides a technical solution: a device for intraperitoneal hyperthermic perfusion chemotherapy, which, when manufactured, mainly includes a liquid storage tank 1 and a medicine dispensing box connected thereto. The medicine dispensing box contains hot liquid medicine for chemotherapy, which is prepared in advance and placed in the medicine dispensing box for heating and heat preservation. The key point is that in the liquid storage tank 1 in this embodiment, an inner lining tube 3 is also coaxially provided. The bottom end of the inner lining tube 3 is closed and is integrally connected to the bottom of the liquid storage tank 1. The two can be integrally formed. There is an annular gap 5 between the inner lining tube 3 and the inner side wall of the liquid storage tank 1. A closing cylinder 2 can be vertically slidably fitted in this annular gap 5, that is, the closing cylinder 2 can be inserted into the annular gap 5. Specifically, the inner liner pipe 3 includes several coaxially connected sub-pipe sections, and a pair of gate plates 4 are installed horizontally sliding and sealingly between the end faces of two adjacent sub-pipe sections. The surface of the gate plates 4 is smooth. Each gate plate 4 faces one side of the annular gap 5, that is, the side located inside the annular gap 5. It is connected to a spherical cap 8 through an elastic element such as a push spring 9, and the spherical cap 8 is pushed by the push spring 9 to the position where the two oppositely arranged gate plates 4 are separated from each other in the assembled state, so that the push spring 9 limits the two gate plates 4 to maintain a normally open non-contact position. When the closing cylinder 2 is axially inserted into the annular gap 5, all the spherical caps 8 can be squeezed toward the inner lining tube 3 so that all the gate plates 4 are close to each other. During production, the gate plates 4 can be made into a semicircular plate structure, and the arc side surfaces thereof can slide out of the inner lining tube 3. Then, after being seamlessly spliced into a circular plate, the inner lining tube 3 is divided into several rated cavities, that is, the space of the pipe section between every two adjacent circular plates constitutes a rated cavity to store a rated amount of liquid medicine. In addition, each rated cavity is connected to an infusion pipe 13 for delivering liquid medicine into the patient's body. Then, during hot infusion, the switch of the corresponding infusion pipe 13 is opened for infusion, and the liquid medicine in the corresponding rated cavity is drained, thereby realizing the infusion of the rated amount of medicine. No additional flow meter is required for metering, and the metering is accurate. Hot infusion treatment can be performed on multiple parts, and there is no need to infuse one by one to save treatment time. There is no need to install multiple pipelines, and each pipeline is installed with a valve, which is complicated. The operation is simple and reliable.

[0030] like Figure 1-3 As shown, the annular blind groove formed by the annular gap 5 is in clearance with the closing cylinder 2, and the inner wall of the closing cylinder 2 has the following Figure 4The plurality of water-passing holes 16 shown are not collinear with the spherical cap 8 in the vertical direction, so as to avoid affecting the contact and cooperation with the spherical cap 8, thereby preventing the insertion of the closing cylinder 2 from being blocked by the liquid in the annular gap 5 when the closing cylinder 2 is inserted. As a result, when the closing cylinder 2 is inserted into the annular blind groove, the liquid in the liquid storage tank 1 can flow upward into the inner liner 3 through the gap between the closing cylinder 2 and the annular blind groove and the water-passing holes 16, and then flow out through the overflow hole 2 at the side wall of the top end of the inner liner 3. 02, flows back to the medicine dispensing box, so that the liquid medicine in the inner lining tube 3 can be in an overflow state. The main purpose of the above structural design is to make the liquid medicine in the liquid storage tank 1 always maintain a rated value, or in other words, to make the liquid medicine in the inner lining tube 3 have a very accurate rated value, because as long as the inner lining tube 3 keeps overflowing, the liquid medicine stored inside must be a rated fixed value, thereby avoiding the problem of flow metering precision control and simplifying the layout and maintenance of the pipeline system. Figure 1 As shown, a screw plug 18 can be detachably installed at the mouth of the inner liner tube 3. The screw plug 18 is connected to a liquid medicine delivery pipe 19 fixed to the outlet end of the medicine dispensing box, and a control valve is provided on the liquid medicine delivery pipe 19. After the screw plug 18 is installed, the medicine dispensing box can inject liquid medicine into the inner liner tube 3. The liquid medicine leaks into the liquid storage tank 1 through the inner liner tube 3, and then flows out through the overflow hole 202 when the set value is reached, so that the liquid storage tank 1 and the inner liner tube 3 have a very accurate rated volume of liquid medicine. In order to push the spherical cap 8 more smoothly, as shown in FIG. Figure 1 The inner wall of the bottom end of the closing cylinder 2 has a rounded corner, which is used for sliding contact with the spherical cap 8. In the specific production, a pouring hole 201 can be opened on the side wall of each sub-tube segment near the gate plate 4 at its lower end. The pouring hole 201 is connected to the pouring pipe 13. Specifically, the pouring pipe 13 can be inserted into the pouring hole 201 for installation. Figure 5 The inlet end of the perfusion pipe 13 should be close to the gate 4 to fully drain the liquid medicine.

[0031] In this embodiment: Figure 1-3 A central guide rod 6 is coaxially fixed at the center of the bottom of the inner liner pipe 3. A plurality of connecting rods 7 are radially installed on the central guide rod 6. The connecting rods 7 are fixedly connected to the inner wall of the sub-pipe segment so that two adjacent sub-pipe segments are coaxially aligned, all the sub-pipe segments are connected in series, and two directly opposite sub-pipe segments are directly opposite each other, so as to be in sliding and extruding contact with the corresponding gate plate 4, thereby forming an integral tubular structure. In practice, a sealing ring can be embedded in the end face of the sub-pipe segment to be in sliding and sealing contact with the gate plate 4, and all the sub-pipe segments are axially compressed when connected in series, thereby forming a whole, and the gate plate 4 can slide relatively radially to separate or connect the inner liner pipe 3.

[0032] In this embodiment: When making the specific Figure 5 The two adjacent sub-pipe segments are coaxially installed with each other in a socket-and-spigot fit, and a compression spring 10 in a compressed state is coaxially sleeved in the annular groove 11 formed by the outer wall of the socket-and-spigot fit. This spring has two functions. First, when the sub-pipe segment at the top is squeezed, a stronger axial series pre-tightening force is formed. Second, when no axial fixed squeezing force is received, the connection function of the compression spring 10 itself is relied on to maintain the integrity of all sub-pipe segments within a certain torque range and prevent them from detaching. At the same time, the center guide rod 6 can be installed in the center of the bottom end of the inner liner pipe 3 in a self-rotating manner, that is, the center guide rod 6 can be installed in a self-rotating manner. Please continue to refer to Figure 1 The central guide rod 6 can be threadedly mounted on a screw plug 18 at the top end of the inner liner pipe 3 and fixed in the form of axial compression. Figure 5 The connecting rod 7 is connected to the threaded section on the central guide rod 6 through a threaded sleeve 17, and a stop rod 12 is also vertically installed at the bottom end of the inner liner pipe 3. The stop rod 12 passes through the connecting rod 7 to prevent the sub-tube segments from rotating; when the central guide rod 6 rotates, the two sub-tube segments can move axially relative to each other due to the limiting effect of the stop rod 12. For example, the above-mentioned compression spring 10 is compressed, and the two sub-tube segments are further inserted and brought closer to each other, and the corresponding connecting rod 7 can slide axially on the stop rod 12, that is, the length of the pipe segment between the two gate plates 4 can be adjusted. When multiple set volumes of liquid medicine are required, the central guide rod 6 can be rotated to obtain a series of rated spaces to pre-store liquid medicine, and then to meet different medication needs during simultaneous infusion in multiple places.

[0033] like Figure 3 and Figure 1-Figure 2 ,as well as Figure 5 There is a bearing shell 14 in the center of the diameter side of this gate plate 4, and a semicircular shell-shaped sealing gasket 15 is embedded in the bearing shell 14. When the two gate plates 4 are spliced together, the two sealing gaskets 15 embrace the central guide rod 6, thereby realizing an axial sliding sealing connection with the central guide rod 6, avoiding leakage at the connection point, and realizing the independence of the areas between the two pairs of gate plates 4 arranged up and down.

[0034] In all the above embodiments, those skilled in the art can adaptively design and improve the specific installation details and drive details of the corresponding components in the intraperitoneal perfusion chemotherapy device. Based on the core technical principles of the above embodiments, conventional designs are sufficient. For example, the device housing can be adaptively designed. For example, the specific structure and drive installation method of the above-mentioned closing cylinder 2 can be that there is a closing plate (not shown in the figure) at the top of the closing cylinder 2, and the above-mentioned perfusion pipe 13 passes through the closing plate in an axially dynamic and sealed manner, so that the closing cylinder 2 can not emit liquid medicine from the central seam at its top when it moves axially, and when in use, the initial position can be that the bottom port of the closing cylinder 2 is located above the top of the liner tube 3, but below the top port of the liquid storage tank 1, and a hydraulic rod can be connected to the closing plate to drive it to move vertically with the closing cylinder 2 to control the volume quantitative interception of the liquid medicine.

[0035] In the above description of the present invention, it should be noted that the terms "one side," "the other side," and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the accompanying drawings, or the orientations or positional relationships in which the inventive product is typically placed when in use. These terms are intended solely to facilitate the description of the present invention and simplify the description, and are not intended to indicate or imply that the devices or components referred to must have, be constructed, or operate in a specific orientation. Therefore, they should not be construed as limitations on the present invention. Furthermore, the terms "first," "second," and the like are used solely for distinction and should not be construed as indicating or implying relative importance.

[0036] Furthermore, the term "identical" and similar terms do not necessarily require that the components be absolutely identical; slight variations are permitted. The term "perpendicular" simply refers to the positional relationship between components being more perpendicular than "parallel," not that the structure must be perfectly vertical; rather, it can be slightly tilted.

[0037] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention and are not limiting. Although the present invention has been described in detail with reference to the preferred embodiments, those skilled in the art should understand that the technical solutions of the present invention may be modified or replaced by equivalents without departing from the purpose and scope of the technical solutions of the present invention, which should all be included in the scope of the claims of the present invention.

Claims

1. A device for intraperitoneal hyperthermic perfusion chemotherapy, comprising a liquid storage tank (1) and a medicine dispensing box connected thereto, wherein the medicine dispensing box contains a hot liquid medicine for chemotherapy, and wherein: An inner lining tube (3) is coaxially provided in the liquid storage tank (1), the bottom end of the inner lining tube (3) is closed and integrally connected to the tank bottom of the liquid storage tank (1), an annular gap (5) is provided between the inner lining tube (3) and the inner side wall of the liquid storage tank (1), and a closing cylinder (2) can be vertically slidably fitted in the annular gap (5); The inner lining pipe (3) comprises a plurality of coaxially connected sub-pipe sections, a pair of gate plates (4) are horizontally slidably and sealingly installed between the end surfaces of two adjacent sub-pipe sections, each gate plate (4) is connected to a spherical cap (8) on one side facing the annular gap (5) via a push spring (9), and the spherical cap (8) is pushed by the push spring (9) to a position where the two oppositely arranged gate plates (4) are separated from each other in the assembled state; When the closing cylinder (2) is axially inserted into the annular gap (5), all the spherical caps (8) are pressed toward the inner lining tube (3) so that all the gate plates (4) are seamlessly spliced with each other, and the inner lining tube (3) is divided into a plurality of rated cavities, each of which is connected to an infusion pipe (13) for delivering a liquid medicine into the patient's body.

2. The intraperitoneal hyperthermic perfusion chemotherapy device according to claim 1, characterized in that: The gate plate (4) is a semicircular structure, and its arc side surface can slide out of the inner lining pipe (3).

3. The intraperitoneal hyperthermic perfusion chemotherapy device according to claim 1, characterized in that: The annular blind groove formed by the annular gap (5) is in clearance fit with the closing cylinder (2), and the inner wall of the closing cylinder (2) has a plurality of water-passing holes (16) that are not vertically colinear with the spherical cap (8), so that when the closing cylinder (2) is inserted into the annular blind groove, the medicine liquid in the liquid storage tank (1) can flow upward into the inner lining tube (3) through the gap between the closing cylinder (2) and the annular blind groove and the water-passing holes (16), and flow back into the medicine dispensing box through the overflow hole (202) at the side wall of the top port of the inner lining tube (3), so that the medicine liquid in the inner lining tube (3) can be in an overflow state.

4. The intraperitoneal hyperthermic perfusion chemotherapy device according to claim 1, characterized in that: A screw plug (18) is detachably mounted on the pipe mouth of the inner lining pipe (3), and a liquid medicine delivery pipe (19) fixed at the outlet end on the medicine dispensing box is connected to the screw plug (18), and a control valve is provided on the liquid medicine delivery pipe (19).

5. The intraperitoneal hyperthermic perfusion chemotherapy device according to claim 1, characterized in that: The inner wall of the bottom port of the shutter cylinder (2) has a rounded corner, and the rounded corner is used for sliding contact with the spherical cover cap (8).

6. The intraperitoneal hyperthermic perfusion chemotherapy device according to claim 1, characterized in that: A perfusion hole (201) is provided on the side wall of each sub-pipe section near the gate plate (4) at its lower end, and the perfusion hole (201) is connected to the perfusion pipe (13).

7. The intraperitoneal hyperthermic perfusion chemotherapy device according to claim 1, characterized in that: A central guide rod (6) is coaxially fixed at the center of the bottom of the inner lining pipe (3), and a plurality of connecting rods (7) are radially installed on the central guide rod (6). The connecting rods (7) are fixedly connected to the inner wall of the sub-pipe segment so that two adjacent sub-pipe segments are coaxially aligned, and the end faces of the two sub-pipe segments facing each other are in sliding and extrusion contact with the corresponding gate plate (4) to form a whole.

8. The intraperitoneal hyperthermic perfusion chemotherapy device according to claim 7, characterized in that: Two adjacent sub-pipe sections are coaxially installed in a socket-and-spigot fit, and a compression spring (10) in a compressed state is coaxially sleeved in an annular groove (11) formed on the outer side walls of the two sub-pipe sections.

9. The intraperitoneal hyperthermic perfusion chemotherapy device according to claim 8, characterized in that: The central guide rod (6) is installed in situ and rotates at the center of the bottom end of the inner lining pipe (3), and can be fixed by axial compression by a screw plug (18) installed at the top end of the inner lining pipe (3) in a threaded manner; the connecting rod (7) is connected to the threaded section on the central guide rod (6) through a threaded sleeve (17), and a stop rod (12) is also vertically installed at the bottom end of the inner lining pipe (3). The stop rod (12) passes through the connecting rod (7). When the central guide rod (6) rotates and causes the two sub-pipe sections to move axially relative to each other, the corresponding connecting rod (7) can slide axially on the stop rod (12).

10. The intraperitoneal hyperthermic perfusion chemotherapy device according to claim 7, characterized in that: A bearing bush (14) is provided at the center of the diameter side of the gate plate (4), and a semicircular shell-shaped sealing gasket (15) is embedded in the bearing bush (14). When the two gate plates (4) are spliced together, the two sealing gaskets (15) embrace the central guide rod (6) to achieve axial sliding sealing with it.

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