A multi-directional guide flow nozzle for intraperitoneal hyperthermic perfusion chemotherapy

Abstract

This invention discloses a multi-directional flow nozzle for intraperitoneal hyperthermic perfusion chemotherapy, belonging to the field of medical device technology. It includes a nozzle body, one end of which is connected to a drainage conduit for connecting to a chemotherapy pump. The nozzle body includes a nozzle head and a connecting tube. One end of the connecting tube is fixedly connected to the nozzle head, and the other end is connected to the drainage conduit. Multiple through holes are evenly distributed on the nozzle head. A rotor is rotatably mounted inside the connecting tube. The connecting tube includes a Venturi tube segment and a connecting section. The rotor is positioned within the throat of the Venturi tube segment. A variable-diameter channel is located at the center of the rotor, and multiple guide vanes are evenly distributed circumferentially along a fixed support rod at the center of the variable-diameter channel. Water flow causes the rotor to rotate, inducing a vortex field in the intraperitoneal medication through the guide vanes. This invention forms a dynamic circulation under pressure, significantly improving the uniformity of contact between the medication and the peritoneal wall, especially small peritoneal metastases. The reaction force of the water flow drives the nozzle head to rotate or form a vortex, greatly improving the therapeutic effect of intraperitoneal hyperthermic perfusion chemotherapy.

Description

Technical Field

[0001] This invention belongs to the field of medical device technology, and more specifically relates to a multi-directional flow nozzle for intraperitoneal hyperthermic perfusion chemotherapy. Background Technology

[0002] A hyperthermic intraperitoneal chemotherapy (HIPEC) device is a medical instrument used for intraperitoneal hyperthermic chemotherapy, primarily for treating malignant tumors within the abdominal cavity, such as gastric cancer, colorectal cancer, ovarian cancer, hepatobiliary and pancreatic cancer, and malignant mesothelioma. The HIPEC device heats the perfusion fluid containing chemotherapy drugs to a specific temperature (usually 43°C) and then continuously circulates it at a constant temperature into the patient's abdominal cavity, maintaining this temperature for a certain period (usually 60 minutes). This treatment method utilizes the synergistic sensitization and perfusion flushing effects of hyperthermic chemotherapy to effectively kill and eliminate free cancer cells and micro-lesions within the body cavity.

[0003] Existing intraperitoneal hyperthermic perfusion techniques mostly employ "low-pressure immersion" or "unidirectional turbulent flow" modes. Current equipment typically administers the medication into the peritoneal cavity via a single perfusion catheter, which is then drained through a drainage tube, creating a circulation. However, this traditional method has the following drawbacks: Distribution limitations: Unidirectional perfusion can easily lead to the formation of a "dominant channel" in the abdominal cavity, meaning that the drug flows only along the path with less resistance. This results in complex anatomical sites such as the abdominal wall, mesentery, and hepatorenal recesses not being adequately and evenly flushed, creating "irrigation blind spots".

[0004] Insufficient flushing force for micrometastases: Peritoneal micrometastases are often hidden in peritoneal folds. Traditional low-pressure soaking methods lack dynamic mechanical flushing force, making it difficult to increase the drug concentration in these deposited tumor cells or drug "dead zones," thus affecting the radical cure effect.

[0005] The contradiction between pressure and safety: While simply increasing the perfusion pressure can enhance the flushing force, it can easily lead to a sudden increase in intra-abdominal pressure, causing the diaphragm to rise and affecting breathing, or even causing anastomotic leakage or leakage of medication through the puncture hole.

[0006] Therefore, there is an urgent need for an infusion device that can maintain effective flushing pressure, guide the uniform distribution of the drug solution, and avoid damage to the abdominal cavity. Summary of the Invention

[0007] In view of this, the present invention provides a multi-directional flow nozzle for intraperitoneal hyperthermic perfusion chemotherapy, which solves the technical problems of uneven drug distribution, insufficient flushing of peritoneal micrometastases and pressure control in the prior art.

[0008] To achieve the above objectives, the present invention adopts the following technical solution: A multi-directional flow nozzle for intraperitoneal hyperthermic perfusion chemotherapy includes a nozzle body, one end of which is connected to a drainage conduit; the drainage conduit is used to connect to a chemotherapy pump; the nozzle body includes a nozzle head and a connecting pipe; one end of the connecting pipe is fixedly connected to the nozzle head, and the other end is connected to the drainage conduit; the nozzle head is uniformly provided with multiple through holes; a rotor is rotatably disposed inside the connecting pipe.

[0009] Furthermore, the nozzle is spherical at the end facing the patient's abdominal cavity.

[0010] Furthermore, both the nozzle and the outer surface of the connecting pipe are covered with a layer of silicone.

[0011] Furthermore, the axis of the through hole is at a certain angle to the straight line from the through hole to the center of the ball.

[0012] Furthermore, the connecting tube includes a Venturi tube section and a connecting section; one end of the connecting section has a narrowed diameter for connecting to the drainage conduit; the rotor is disposed within the throat of the Venturi tube section; a variable diameter channel is provided at the center of the rotor, and the diameter of the variable diameter channel gradually increases from the inlet section of the Venturi tube section to the diffuser section.

[0013] Furthermore, a fixed support rod is provided at the center of the variable diameter channel; a fixed plate is provided at one end of the variable diameter channel near the inlet section, the outer side of the fixed plate is fixedly connected to the side wall of the variable diameter channel, and the center is fixedly connected to the fixed support rod; a plurality of guide vanes are evenly arranged above the fixed plate along the circumference of the fixed support rod, and the inner side of the guide vanes is engaged with the fixed support rod.

[0014] Furthermore, the fixed plate is provided with a plurality of water passage grooves along the circumference of the fixed support rod; the gap between two adjacent sets of guide vanes corresponds one-to-one with the water passage grooves, and the water passage grooves and gaps form a water outlet slit.

[0015] Furthermore, the guide vane is angled relative to the plane containing the radial line of the rotor, so that the water flow direction of the outlet slit forms a certain angle with the water flow direction of the drainage pipe.

[0016] The beneficial effects of this invention are as follows: This invention provides a multi-directional flow nozzle for intraperitoneal hyperthermic perfusion chemotherapy. Addressing the problems of uneven drug distribution and insufficient flushing force in existing intraperitoneal hyperthermic perfusion chemotherapy methods, a multi-directional flow nozzle is installed at the end of the drainage catheter. A rotor is installed inside the nozzle; water flow causes the rotor to rotate, inducing a vortex field in the peritoneal fluid through guide plates. Through-holes at the nozzle end enable multi-angle pressurized flushing, forming a dynamic circulation under pressurization. This significantly improves the uniformity of contact between the drug and the peritoneal wall, especially small peritoneal metastases. The reaction force of the water flow drives the nozzle to rotate or form a vortex, transforming the traditional "static pressurization" into "dynamic agitation," greatly improving the therapeutic effect of intraperitoneal hyperthermic perfusion chemotherapy. Attached Figure Description

[0017] To more clearly illustrate the technical solutions in the embodiments of the present invention or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only embodiments of the present invention. For those skilled in the art, other drawings can be obtained based on the provided drawings without creative effort.

[0018] Figure 1 This is a schematic diagram of the overall structure of the present invention.

[0019] Figure 2 This is a schematic diagram of the internal structure of the present invention.

[0020] Figure 3 This is a cross-sectional view of the rotor of the present invention.

[0021] Figure 4 This is a top view of the rotor of the present invention.

[0022] In the figure: 1- Nozzle body; 2- Drainage conduit; 3- Nozzle; 31- Through hole; 4- Connecting pipe; 41- Venturi tube section; 42- Connecting section; 5- Silicone layer; 6- Rotor; 61- Variable diameter channel; 62- Fixed support rod; 63- Fixed plate; 64- Guide vane; 65- Water passage; 7- Bearing. Detailed Implementation

[0023] The technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0024] Please see the appendix Figure 1-4The present invention provides a multi-directional flow nozzle for intraperitoneal hyperthermic perfusion chemotherapy, comprising a nozzle body 1, one end of which is connected to a drainage conduit 2; the drainage conduit 2 is used to connect to a chemotherapy pump.

[0025] The nozzle body 1 includes a nozzle 3 and a connecting tube 4; the nozzle 3 is spherical with a hollow interior, located at one end facing the patient's abdominal cavity; one end of the connecting tube 4 is fixedly connected to the nozzle 3, and the other end is connected to the drainage tube 2.

[0026] Both the nozzle 3 and the connecting pipe 4 are wrapped with a layer of silicone 5 on their outer surfaces. The silicone layer is soft and has rounded edges without sharp corners, which prevents damage to the peritoneum and intestinal serosa when the nozzle moves or comes into contact with the abdominal cavity.

[0027] Multiple through holes 31 are evenly arranged within the top hemisphere of the nozzle 3, and the axis of the through hole 31 is at a certain angle to the straight line from the through hole 31 to the center of the sphere.

[0028] The connecting tube 4 includes a venturi section 41 and a connecting section 42; one end of the connecting section 42 has a narrowed diameter for connecting to the drainage conduit 2; a rotor 6 is rotatably provided at the throat of the venturi section 41, and the rotation of the rotor 6 due to the impact of the liquid can increase the pressure of the liquid and form a vortex.

[0029] The rotor 6 is rotatably mounted in the center of the throat of the Venturi tube section 41 via the bearing 7; the rotor 6 has a variable diameter channel 61 at its center, and the diameter of the variable diameter channel 61 gradually increases from the inlet section to the diffuser section of the Venturi tube section 41.

[0030] A fixed support rod 62 is provided at the center of the variable diameter channel 61; a fixed plate 63 is provided at one end of the variable diameter channel 61 near the inlet section, the outer side of the fixed plate 63 is fixedly connected to the side wall of the variable diameter channel 61, and the center is fixedly connected to the fixed support rod 62.

[0031] Multiple water passage grooves 65 are arranged on the fixed plate 63 along the circumference of the fixed support rod 62; multiple guide vanes 64 are evenly arranged on the upper part of the fixed plate 63 along the circumference of the fixed support rod 62, and the inner side of the guide vanes 64 is engaged with the fixed support rod 62. The gap between two adjacent sets of guide vanes 64 corresponds one-to-one with the water passage grooves 65, and the water passage grooves 65 and the gaps form a water outlet slit, allowing the liquid medicine to enter the nozzle 3 through the water outlet slit.

[0032] The guide vane 64 is set at an angle relative to the radial line of the rotor 6, so that the water flow direction of the outlet slit forms a certain angle with the water flow direction of the drainage pipe 2.

[0033] The drug solution impacts the rotor 6, and is ejected tangentially through the water outlet slit. The combined action of multiple tangentially ejected liquid streams induces a slowly rotating vortex field around the nozzle and even throughout the peritoneal cavity. This vortex drives the overall flow of the drug solution within the peritoneal cavity, ensuring continuous and uniform contact between the chemotherapy drug and the peritoneal wall. This allows the drug solution to reach the dead zones of the peritoneum, effectively flushing and covering micrometastases in the peritoneum.

[0034] The various embodiments in this specification are described in a progressive manner, with each embodiment focusing on its differences from other embodiments. Similar or identical parts between embodiments can be referred to interchangeably. For the apparatus disclosed in the embodiments, since they correspond to the methods disclosed in the embodiments, the description is relatively simple; relevant parts can be referred to the method section.

[0035] The above description of the disclosed embodiments enables those skilled in the art to make or use the invention. Various modifications to these embodiments will be readily apparent to those skilled in the art, and the general principles defined herein may be implemented in other embodiments without departing from the spirit or scope of the invention. Therefore, the invention is not to be limited to the embodiments shown herein, but is to be accorded the widest scope consistent with the principles and novel features disclosed herein.

Claims

1. A multi-directional flow nozzle for intraperitoneal hyperthermic perfusion chemotherapy, characterized in that, The device includes a nozzle body (1), one end of which is connected to a drainage conduit (2); the drainage conduit (2) is used to connect to a chemotherapy pump; the nozzle body (1) includes a nozzle (3) and a connecting pipe (4); one end of the connecting pipe (4) is fixedly connected to the nozzle (3), and the other end is connected to the drainage conduit (2); a plurality of through holes (31) are evenly arranged on the nozzle (3); a rotor (6) is rotatably arranged inside the connecting pipe (4).

2. The multi-directional flow nozzle for intraperitoneal hyperthermic perfusion chemotherapy according to claim 1, characterized in that, The nozzle (3) is spherical at the end facing the patient's abdominal cavity.

3. The multi-channel nozzle for intraperitoneal hyperthermic perfusion chemotherapy according to claim 1, characterized in that, The outer surfaces of the nozzle (3) and the connecting pipe (4) are both covered with a layer of silicone (5).

4. The multi-directional flow nozzle for intraperitoneal hyperthermic perfusion chemotherapy according to claim 1, characterized in that, The axis of the through hole (31) is at a certain angle to the straight line from the through hole (31) to the center of the ball.

5. The multi-channel nozzle for intraperitoneal hyperthermic perfusion chemotherapy according to claim 1, characterized in that, The connecting tube (4) includes a Venturi tube section (41) and a connecting section (42); the diameter of one end of the connecting section (42) is narrowed to connect to the drainage conduit (2); the rotor (6) is located in the throat of the Venturi tube section (41); a variable diameter channel (61) is provided in the center of the rotor (6), and the diameter of the variable diameter channel (61) gradually increases from the inlet section to the diffuser section of the Venturi tube section (41).

6. The multi-channel nozzle for intraperitoneal hyperthermic perfusion chemotherapy according to claim 5, characterized in that, A fixed support rod (62) is provided at the center of the variable diameter channel (61); a fixed plate (63) is provided at one end of the variable diameter channel (61) near the inlet section, the outer side of the fixed plate (63) is fixedly connected to the side wall of the variable diameter channel (61), and the center is fixedly connected to the fixed support rod (62); a plurality of guide vanes (64) are evenly arranged on the upper part of the fixed plate (63) along the circumference of the fixed support rod (62), and the inner side of the guide vanes (64) is engaged with the fixed support rod (62).

7. The multi-channel nozzle for intraperitoneal hyperthermic perfusion chemotherapy according to claim 6, characterized in that, Multiple water passage grooves (65) are provided on the fixed plate (63) along the circumference of the fixed support rod (62); the gap between two adjacent sets of guide vanes (64) corresponds one-to-one with the water passage grooves (65), and the water passage grooves (65) and the gaps form a water outlet slit.

8. The multi-channel nozzle for intraperitoneal hyperthermic perfusion chemotherapy according to claim 7, characterized in that, The guide vane (64) is set at an angle relative to the radial line of the rotor (6), so that the water flow direction of the outlet slit forms a certain angle with the water flow direction of the drainage pipe (2).

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