The invention belongs to the medical apparatus and instrument technical field and relates to a radiation protection cover for the department of radiotherapy. The radiation protection cover comprises aradiotherapy platform, telescopic bars, a lower radiation protection cover, an upper radiation protection cover, claiming slots, a positioning box, handles, electronic valves, radiotherapy holes, anextension plate, a control panel, a holographic projection camera, a fixed board, a display screen, a human body diagram and a marking pen; the telescopic bars are respectively arranged at the four corners of the upper surface of the radiotherapy platform; the tops of the two telescopic bars on the edge of the tail of the radiotherapy platform are provided with the lower radiation protection cover; and the tops of the two telescopic bars on the edge of the head of the radiotherapy platform are provided with the upper radiation protection cover. With the radiation protection cover of the invention adopted, the radiation protection for the whole body of a patient can be realized; the single disease portion of the patient can be treated; an irradiation area near the disease portion of the patient can be decreased, so that damage to the benign tissues and organs of the patient can be effectively prevented; and holographic projection can be carried out, so that medical staff can promptly understand the treatment status of the patient and mark the disease portion of the patient. The radiation protection cover has high practicality.