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135 results about "Burn wound" patented technology

A burn is an injury to the flesh caused by such things… Burn wound care is important to avoid infection and help the healing process. A burn is an injury to the flesh caused by such things as heat, chemicals, friction or electricity. These wounds can range in severity by degrees and,...

Intelligent burn wound dynamic monitoring and evaluation system

The invention relates to the technical field of burn wound treatment, and discloses an intelligent burn wound dynamic monitoring and evaluation system. The system comprises a data acquisition module for acquiring real-time physiological data of a burn wound by using a multi-source sensor; the multi-modal feature fusion module is used for generating wound comprehensive state features based on a deep belief network; the dynamic evaluation module outputs a wound healing level and a risk early warning signal through a pre-trained collaborative evaluation model; the optimization decision generation module is used for constructing a multi-target dynamic optimization model to adjust a treatment scheme according to risk early warning; and the hierarchical execution control module realizes distributed execution of treatment instructions through a hierarchical control architecture. The system can comprehensively monitor the state of the wound surface, accurately evaluate the healing risk, optimize the treatment scheme and accurately execute the treatment scheme, effectively improve the treatment effect of the burn wound surface, reduce the infection risk and shorten the healing period, and has important clinical application value.
Owner:MEI HOSPITAL UNIV OF CHINESE ACAD OF SCI

Burn and damaged skin recovery degree evaluation method based on skin image recognition

The invention discloses a burn and damaged skin recovery degree evaluation method based on skin image recognition, and the method comprises the steps: obtaining a visible light image and an infrared thermal imaging image of a skin burn patient, carrying out the preprocessing, and fusing into a skin burn image; performing feature extraction, recognition and segmentation to obtain a burn area image; constructing a static feature set based on the burn feature parameters, constructing a three-dimensional model of the burn wound based on the burn area image and the depth image, and constructing a dynamic feature set; and inputting the extracted static and dynamic features into the optimized deep learning-support vector machine fusion model for training, carrying out final classification on a recovery stage, and calculating the time required for complete healing. The method provided by the invention not only can effectively capture the static feature information of the burn area, but also can dynamically monitor the recovery change trend of the wound in real time, accurately predict the time required for complete healing, and can significantly improve the accuracy and personalized assistance of burn diagnosis and treatment.
Owner:FIRST HOSPITAL AFFILIATED TO GENERAL HOSPITAL OF PLA

Burn wound image detection method based on attention-enhanced convolutional neural network

The invention discloses a burn wound image detection method based on an attention-enhanced convolutional neural network, and belongs to the field of medical image artificial intelligence target detection. The method comprises the following steps: establishing and marking a burn wound skin image data set, introducing a Swin Transform and an LSKA attention module in series behind a spatial pyramid pooling fast module (SPPF) at a backbone part of a YOLOv11 network, forming an enhanced Backbone of SPPF-Swin-LSKA, and realizing collaborative optimization of global modeling and local detail perception; and cross-layer feature routing and multi-scale prediction layer configuration are redesigned at a Head end so as to improve the detection capability of a small target and the recognition performance under a complex background. The method can effectively reduce missing detection and false detection, improves the detection stability and robustness, and has good real-time performance and clinical application value.
Owner:SHANGHAI UNIV

Burn wound area segmentation method and system

The invention provides a burn wound area segmentation method and system, and the method comprises the steps: obtaining a to-be-segmented image through constructing an anatomy database, and employing a lightweight CNN classifier to extract a feature vector; determining a healing stage of the burn wound according to the feature vector, and adjusting boundary parameters according to the healing stage; inputting an image to be segmented into the improved U-Net encoder network, and outputting a segmentation mask and a boundary probability graph; determining an interaction area according to the boundary probability graph, carrying out interaction in the interaction area by referring to the segmentation mask, and generating a smooth boundary according to interaction data; and post-processing optimization fused with prior constraints is performed on the smooth boundary to obtain a target boundary so as to complete burn wound area segmentation, specific and prior knowledge provides basic constraints for segmentation, interactive operation pertinently corrects a complex area, post-processing realizes global consistency optimization, and a'constraint-correction-optimization 'closed-loop processing flow is formed.
Owner:NANCHANG HIGH-TECH ZONE PEOPLES HOSPITAL

Dressing for promoting pain relieving and regeneration of burn wound and preparation method thereof

The invention discloses a dressing for promoting pain relief and regeneration of burn wounds and a preparation method of the dressing. The dressing comprises a drug delivery carrier and slow-release multi-effect hydrogel loaded on the drug delivery carrier, the slow-release multi-effect hydrogel is prepared from the following raw materials in parts by weight: 100 parts of water, 7 to 35 parts of multi-effect slow-release microspheres, 3.5 to 10 parts of sodium carboxymethyl cellulose, 2.5 to 8 parts of sodium hyaluronate and 0.5 to 4 parts of glycerol. The dressing provided by the invention has the effects of relieving wound pain, promoting wound regeneration and inhibiting and killing bacteria, the effect of the dressing is long-acting by realizing slow release of various active components (antibacterial carbon dots, silver nanoparticles and bletilla striata polysaccharide), and the dressing has a good application prospect by virtue of matching of the active components and the slow-release effect of the active components. The nursing and treatment effects of burn wounds can be effectively improved, and the application prospect is very good.
Owner:GENERAL HOSPITAL OF PLA

Intelligent dynamic negative pressure and phototherapy integrated burn wound treatment device

The invention relates to an intelligent dynamic negative pressure and phototherapy integrated burn wound treatment device, and belongs to the technical field of medical instruments, the device comprises a contact layer, a conduction layer and a honeycomb support layer, the contact layer drains exudate, the conduction layer is integrated with an optical fiber network and a self-adaptive deformation mechanism, and the honeycomb support layer is connected with an intelligent negative pressure chamber and a gradient sterilization system. The pressure of the negative pressure chamber is dynamically adjusted through a corrugated air bag and a rhombic telescopic unit, and the photo-thermal assembly irradiates the wound surface in a time-sharing mode and maintains the constant temperature. And the sterilization system adopts ultraviolet pulse and a multi-stage filter screen to cooperatively purify the percolate. The intelligent regulation and control module optimizes treatment parameters in real time through a multi-mode sensing network, and full-closed-loop cooperation of negative pressure, phototherapy and sterilization is achieved. According to the device, the limitation of traditional treatment is broken through through integrated design, the wound repairing quality and the anti-infection capacity are remarkably improved, meanwhile, the medical care burden is reduced through modular expansion and a non-invasive monitoring function, and an efficient and safe intelligent solution is provided for burn management.
Owner:THE FIRST AFFILIATED HOSPITAL OF ARMY MEDICAL UNIV

Burn wound infection early warning method and system based on infrared thermal imaging monitoring

The invention relates to the technical field of temperature mapping, in particular to a burn wound infection early warning method and system based on infrared thermal imaging monitoring, and the method comprises the following steps: extracting an image temperature recombination thermal matrix, recognizing a contour, screening edge fluctuation, trimming a thermal difference to track a heat flow path, calculating a drift trajectory, and analyzing heat value mutation. And a wound infection early warning scheme is obtained. According to the invention, through temperature reconstruction and thermal difference distribution analysis of an infrared image, a wound surface hot area range and a thermal energy gathering trend are accurately identified, dynamic tracking of edge thermal drift is realized in combination with a heat flow path and a heat value change direction, and a multi-layer heat map structure is constructed by using heat value increasing and climbing mutation characteristics. According to the method, the identification precision and infection risk early warning capability of a thermal abnormal region are improved, the sequential expression and spatial structure definition of temperature change are enhanced, the fuzzy problem of a static heat map is improved, and continuous monitoring of the thermal evolution process of a wound surface and directional positioning of a high-risk region are realized.
Owner:THE FIRST AFFILIATED HOSPITAL OF ARMY MEDICAL UNIV

Microcapsule controlled-release medical dressing and preparation method thereof

The invention relates to the technical field of medical supplies, and discloses a microcapsule controlled-release medical dressing and a preparation method thereof.The microcapsule controlled-release medical dressing comprises a base cloth layer, a microcapsule layer arranged on one side of the base cloth layer and a protective layer covering the microcapsule layer; the microcapsule layer is composed of a plurality of drug-loaded microcapsules, each microcapsule is composed of a wall material and a core material, the core material is a wound treatment drug, and the wall material is a modified chitosan-sodium alginate composite wall material; the base cloth layer is a polyurethane non-woven fabric with air holes, and the protective layer is a degradable hyaluronic acid film. The microcapsule is suitable for various types of wounds, such as surgical incisions, burn wounds, chronic ulcers and the like, different wound treatment requirements can be met by adjusting the types of antibiotics in the microcapsule, the crosslinking degree of the wall materials and the drug loading capacity, and the microcapsule has a wide clinical application prospect.
Owner:连云港美顺医疗用品有限公司

MXene modified and engineered exosome loaded GelMA hydrogel, preparation method thereof and application thereof in preparation of burn wound repair products

The invention provides MXene modified and engineered exosome loaded GelMA hydrogel, a preparation method thereof and application of the MXene modified and engineered exosome loaded GelMA hydrogel in preparation of burn wound repair products, and belongs to the technical field of medical biology. The preparation method comprises the following steps: introducing the anti-tagomiR-192-5p into mesenchymal stem cell MSCs exosome through an electroporation technology to obtain an exosome preparation for promoting wound healing based on regulation and control of the miR-192-5p, and recording the exosome preparation as Exo-anti-tagomiR-192-5p; the preparation method comprises the following steps: mixing Exo-antitago miR-192-5p, MXene and a methacrylated gelatin solution, so as to obtain the Exo-antitago miR-192-5p (at) M-GelMA hydrogel. The preparation method comprises the following steps: mixing the Exo-antitago miR-192-5p (at) with the methacrylated gelatin solution; in a mouse burn model, after the hydrogel is used, the wound closing speed is obviously increased, the inflammatory reaction is obviously relieved, and the tissue regeneration quality is higher.
Owner:THE FIRST AFFILIATED HOSPITAL OF NAVAL MEDICAL UNIVERSITY OF CHINESE PEOPLES LIBERATION ARMY

Controlled hydrogel delivery of focal adhesion kinase inhibitor for decreased scar formation

PendingUS20260137839A1Organic active ingredientsAbsorbent padsPullulanExcisional wound
The formation of scars at a wound site is reduced by contacting the wound site with an effective dose of an inhibitor of focal adhesion kinase (FAK) formulated in a pullulan hydrogel. The release profile of the FAK inhibitor can be adjusted according to the nature of the wound, e.g., excisional wounds, burn wounds, etc.
Owner:THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIV

Oil gel based on hermetia illucens oil as well as preparation method and application of oil gel

The invention discloses oil gel based on hermetia illucens oil as well as a preparation method and application of the oil gel, and relates to the technical field of biological medicines. According to the oil gel based on the hermetia illucens oil, the hermetia illucens oil is used as a grease matrix, and a stable lipid network structure is constructed by combining monoglyceride from hermetia illucens and vegetable wax. The hermetia illucens oil is derived from an animal lipid metabolism system, the fatty acid chain length distribution, the polarity characteristic and other aspects of the hermetia illucens oil are highly similar to those of a human skin cuticle lipid system, a continuous lipid covering layer can be formed on the surface of a burn wound, and the wound barrier condition is effectively improved; meanwhile, antioxidant fat-soluble components contained in the hermetia illucens oil are beneficial to reducing the local oxidative stress level of the wound surface and improving the microenvironment of the wound surface. The oleogel provided by the invention is suitable for external nursing of burn wounds, has dual functions of bionic barrier construction and antioxidant synergistic regulation, and can provide a novel and efficient biomedical material for burn wound repair.
Owner:WUHAN POLYTECHNIC UNIVERSITY

Antibacterial burn gel and preparation method thereof

The invention relates to the technical field of burn gels, in particular to an antibacterial burn gel and a preparation method thereof.The preparation method comprises the following steps that carbomer is dispersed in water, standing and swelling are conducted, and a primary gel matrix is obtained; stirring the primary gel matrix, sequentially adding emulsified silicone oil, ethanol, a disodium ethylene diamine tetraacetate solution and an emulsifier, and stirring to obtain a mixture A; adding silver salt and modified hydroxyapatite nanorods into the mixture A, and stirring to obtain a mixture B; the pH value of the mixture B is adjusted to 6.5-7.5, and the antibacterial burn gel is obtained. According to the invention, silver salt is introduced to endow the burn gel with excellent antibacterial performance; the hydroxyapatite nanorods are introduced, so that the problem that the antibacterial property is reduced due to silver ion precipitation is solved, the biocompatibility and the heat dissipation effect of the gel are synchronously enhanced, and a more efficient and safer solution is provided for antibacterial and repair of burn wounds.
Owner:ROOSIN MEDICAL CO LTD

Traditional Chinese medicine composition for promoting burn wound healing and preparation method and application thereof

The invention provides a traditional Chinese medicine composition for promoting burn wound healing and a preparation method and application thereof, and belongs to the technical field of traditional Chinese medicine. The traditional Chinese medicine composition comprises the following components in parts by weight: 15-20 parts of fructus cnidii; 20-40 parts of sargentgloryvine stem; 20 to 40 parts of dandelion; 20 to 40 parts of polygonum cuspidatum; 25 to 30 parts of cortex phellodendri; 25 to 30 parts of radix sophorae flavescentis; 10 to 15 parts of Chinese gall; 1-5 parts of a temperature slow release agent; 1 to 5 parts of mucus polysaccharide; wherein the temperature slow-release agent is prepared from menthol glucoside, tris (hydroxymethyl) aminomethane and sodium alginate. The traditional Chinese medicine composition is prepared by compounding fructus cnidii, sargentgloryvine stem, dandelion, polygonum cuspidatum, golden cypress, radix sophorae flavescentis and gallnut, has the efficacy of resisting inflammation, resisting bacteria, promoting healing, astringing to relieve pain and the like, and is combined with the temperature slow-release agent and mucous polysaccharide, so that the temperature required during fumigation and washing is effectively regulated and controlled while the efficacy is promoted, and the fumigation and washing effects are improved. And the secondary injury of the wound surface caused by improper control of the fumigation and washing temperature is avoided.
Owner:NANCHANG HIGH-TECH ZONE PEOPLES HOSPITAL

Fibrin particles and methods of making the same

Disclosed herein are low density particles comprising polymerized fibrin that are micrometer or nanometer sized in diameter. The particles can further include at least one therapeutic agent. The particles may be used to treat wounds, by administration directly or systemically to the site of the wound. Exemplary wounds that may be treated with the fibrin particles include a trauma wound, a surgical wound, a burn wound, or an ulcer wound. Also disclosed herein are methods for preparing the particles using a shearing process.
Owner:NORTH CAROLINA STATE UNIV

Application of exosomes from rabdosia rubescens in preparation of drugs for promoting wound healing

PendingCN122440696APharmaceutical drugFibroblast migration
The present application relates to the field of biotechnology, in particular to the application of Radix Rabdosiae Rubescens derived exosomes in the preparation of a drug for promoting wound healing, wherein the prepared Radix Rabdosiae Rubescens derived exosomes are uniform in size, good in appearance, can promote cell proliferation, have good effects of promoting fibroblast migration and reducing scar formation; and a scar-free wound healing hydrogel containing Radix Rabdosiae Rubescens derived exosomes is also provided, wherein the hydrogel can encapsulate rEVs or ORI, can effectively increase the proportion of type III collagen in the new skin tissue, effectively reduce the formation of scars, effectively promote the healing of deep second-degree burn wounds, and effectively inhibit the MMT process of macrophages in the wound healing process, and has a wide application prospect in the field of scar prevention and treatment.
Owner:XINXIANG MEDICAL UNIV

A traditional Chinese medicine composition for treating skin trauma, a preparation method thereof and application thereof

This invention provides a traditional Chinese medicine composition for treating skin trauma, its preparation method, and its application, relating to the field of traditional Chinese medicine technology. The traditional Chinese medicine composition of this invention comprises the following raw materials in parts by weight: Astragalus membranaceus 20-30 parts, Piper kadsura vine 20-30 parts, Dragon's blood 10-20 parts, Rheum palmatum 3-8 parts, Coptis chinensis 3-8 parts, Phellodendron chinense 3-8 parts, Angelica sinensis 8-15 parts, Panax notoginseng 1-5 parts, Angelica dahurica 5-10 parts, Rehmannia glutinosa 5-10 parts, Scrophularia ningpoensis 3-8 parts, Aucklandia lappa 1-5 parts, Paeonia suffruticosa 5-10 parts, Rosin 3-8 parts, Vespa nidus 10-15 parts, and Carbonized human hair 1-5 parts. The various medicinal materials of this invention interact and complement each other, possessing the effects of promoting diuresis and reducing swelling, promoting tissue regeneration and detoxification, anti-inflammatory and analgesic effects, and activating blood circulation and removing blood stasis. It can reduce tissue swelling and redness, effectively prevent infection of burn wounds, and improve wound healing speed. It has significant therapeutic effects on skin trauma caused by burns and scalds, with no toxic side effects.
Owner:SHAANXI XINFENGHE PHARM CO LTD

A moisturizing device for burn and plastic surgery care

The present application belongs to the technical field of medical equipment, and discloses a moisturizing device for burn plastic surgery nursing, which comprises a moisturizing cover, a water tank, a heater, an atomizer, a fan and a power supply. The moisturizing cover is hemispherical and made of transparent plastic, the inner surface of the moisturizing cover is covered with multiple layers of microporous membranes, the outer surface of the moisturizing cover is provided with multiple ventilation holes, the lower end of the moisturizing cover is open and used for being sleeved on a burn wound surface, the upper end of the moisturizing cover is provided with an air inlet and an air outlet; the water tank is used for storing a solution, the lower part of the water tank is provided with a water outlet connected with a water pump, the other end of the water pump is connected with the air inlet of the moisturizing cover through a water pipe, a valve is arranged on the water pipe and used for controlling the size of water flow; the heater is used for heating the solution in the water tank; the atomizer is used for atomizing the solution delivered by the water pump; the fan is used for discharging air and water mist in the moisturizing cover; the power supply is used for providing power for the water pump, the heater, the atomizer and the fan, a switch is arranged on the power supply and used for controlling the on-off of the power supply; and the controller is used for controlling the working state of the moisturizing device.
Owner:THE FIRST AFFILIATED HOSPITAL OF ARMY MEDICAL UNIV

Pseudomonas aeruginosa flagella inhibiting peptide and synthesis method and application thereof

The application discloses a flagellum inhibiting peptide of pseudomonas aeruginosa and a preparation method and application thereof, and the sequence of the flagellum inhibiting peptide is Lys-Ile-Gly-Leu-Phe-Arg-Trp-Arg. The synthetic inhibiting peptide has a time-dependent self-assembly ability, can gradually evolve from scattered granular into filamentous structure, and finally forms a stable net-like morphology. The synthetic inhibiting peptide can significantly inhibit the flagellum motility of PAO1 and other strains of pseudomonas aeruginosa, and has synergistic antibacterial activity when combined with allicin, ciprofloxacin, meropenem, levofloxacin, polymyxin B and the like. Moreover, the synthetic inhibiting peptide has obvious bacteriostatic and healing-promoting effects on burn wound infection.
Owner:NANJING UNIV OF TRADITIONAL CHINESE MEDICINE

Anti-adhesion burn dressing equipment

The present invention relates to the technical field of auxiliary medicine application equipment for burn patients, specifically to an anti-adhesion burn dressing change device, comprising a chassis, an automatic gauze winding unit fixed on the chassis, and an anti-adhesion unit, wherein a through circular hole is provided in the middle of the chassis; the automatic gauze winding unit comprises a shaft sleeve fixed in the chassis, a bearing fixed on the outer circle of the shaft sleeve, a gear ring fixed on the outer ring of the bearing, and a core shaft threadedly connected to the end face of the gear ring, gauze is wound on the core shaft, and the core shaft can rotate coaxially around the circular hole; the anti-adhesion unit comprises a container box fixed on the surface of the chassis and a medicine dispensing mechanism arranged in the container box, the container box is located directly above the central axis of the circular hole, the lower end of the container box is provided with a conical medicine dispensing hole, and the medicine dispensing mechanism is used to block or open the medicine dispensing hole. The present invention can assist medical staff in completing gauze bandaging and performing anti-adhesion treatment on the wound during the dressing change process for hand burn wound care, thereby reducing the workload of medical staff and promoting wound recovery.
Owner:THE FIRST AFFILIATED HOSPITAL OF ARMY MEDICAL UNIV

Convenient dressing change treatment device for burn wound repair

The invention discloses a convenient dressing change treatment device for burn wound repair, which comprises a bottom clamping group shell, a corrugated group shell is fixedly arranged at the upper end of the bottom clamping group shell, the corrugated group shell is made of a silica gel material, a top clamping group shell is fixedly arranged at the upper end of the corrugated group shell, and an air hole is formed in the upper end of the top clamping group shell. The bottom clamping group shell is movably connected with the top clamping group shell through a fixing assembly, the bottom end of the bottom clamping group shell is fixedly provided with an attaching bottom group shell, and the inner walls of the bottom clamping group shell and the top clamping group shell are uniformly and fixedly provided with limiting assemblies; dynamic angle adjustment between the bottom clamping assembly shell and the top clamping assembly shell is allowed, the requirement for flexion and extension of finger joints is perfectly met, and the problem of joint stiffness caused by a traditional rigid brace is solved.
Owner:乐清市人民医院

Glyceroglucoside-containing antibacterial repair medical gel and preparation method thereof

The invention relates to a bacteriostatic repair medical gel containing glycosylglycerol and a preparation method thereof, and belongs to the technical field of medical dressings. The gel is prepared by taking glycosylglycerol as a main active component and cooperating with chitosan, collagen, a silver ion antibacterial agent and other components through a specific process. The gel has triple synergistic effects: glycosylglycerol enhances the skin barrier function and provides lasting moisture retention by activating aquaporin; chitosan and silver ions provide broad-spectrum antibacterial activity; and collagen and glucan promote tissue repair and cell proliferation. Experiments show that the antibacterial rate of the gel on common pathogenic bacteria such as staphylococcus aureus and escherichia coli exceeds 99.9%, meanwhile, the wound healing speed can be increased by 40% or above, and the gel is good in biocompatibility and free of skin irritation. The gel can be used for repairing and nursing various skin injuries such as burn wounds, chronic ulcers and surgical wounds.
Owner:青岛中科蓝智生物科技发展有限公司

Seepage management and self-power generation double-bionic wound dressing as well as preparation method and application thereof

ActiveCN120733098APlastersAdhesive dressingsActive Ion TransportWound dressing
The invention discloses a double-bionic wound dressing with seepage management and self-power generation functions as well as a preparation method and application of the double-bionic wound dressing. The double-bionic wound dressing comprises a first electrode layer, a blocking layer, a moisture absorption power generation layer, a diffusion antibacterial layer, an evaporation power generation layer and a second electrode layer which are sequentially stacked from bottom to top. The electrostatic spinning fiber membrane with high biocompatibility is adopted, a liquid transport mechanism of plant transpiration and an ion active transport principle of electric ray power generation cells are combined through bionic design, the triple functions of wound surface antibiosis, efficient seepage management and stable power generation are achieved, the wound surface microenvironment is regulated and controlled, and the wound surface antibacterial effect is achieved. Excessive inflammation caused by seepage accumulation is effectively avoided, fibroblast migration, angiogenesis and skin appendage regeneration are remarkably promoted, wound healing is accelerated, skin function recovery is facilitated, and a new treatment mode is provided for burn wound repair.
Owner:WUHAN UNIV OF TECH

Zinc-doped antibacterial carbon dots and preparation method and application thereof

The present application relates to a kind of zinc-doped antibacterial carbon dots and its preparation method and application, the preparation method of the zinc-doped antibacterial carbon dots is that biomass, anhydrous zinc acetate is dispersed in deionized water according to mass ratio, after ultrasonic stirring, mixed solution is obtained, after hydrothermal reaction, mixed solution is obtained after natural cooling, centrifugal, filtration treatment, carbon dot solution is obtained, carbon dot solution is obtained after freeze-drying treatment, and powder zinc-doped antibacterial carbon dots are obtained.Then zinc-doped antibacterial carbon dots are dissolved in double distilled water with carboxymethyl chitosan, bioactive glass according to proportion, stirring is obtained at room temperature, and composite hydrogel is obtained.The zinc-doped antibacterial carbon dots and composite hydrogel prepared in the present application have good antibacterial effect, the preparation process of composite hydrogel is simple, low in cost, low in cytotoxicity, and zinc-doped antibacterial carbon dots have wide application prospect in the preparation of antibacterial material and the treatment of skin deep lesions, diabetic wound and burn wound dressing material.
Owner:HEFEI UNIV OF TECH

Traditional Chinese medicine alcohol dressing and use method

PendingCN122351570AAfter treatmentAlcohol
This invention belongs to the field of medical pharmaceuticals, specifically relating to a traditional Chinese medicine alcohol dressing and its application method; a traditional Chinese medicine alcohol dressing comprising one of Lithospermum erythrorhizon, borneol, or Polygonum cuspidatum, and alcohol; the weight ratio of one of Lithospermum erythrorhizon, borneol, or Polygonum cuspidatum to alcohol is 1.5–2:10; a method of applying the traditional Chinese medicine alcohol dressing includes the following steps: clearing static electricity; spraying the traditional Chinese medicine and alcohol onto the wound and blisters, avoiding the mouth, eyes, ears, and nose, for rapid pain relief and heat dissipation; preserving the intact wound and blisters; implementing corresponding treatment measures according to the type of burn; discharge from the hospital after treatment and rest at home to allow the biological cells' electromagnetic sensing self-healing ability to recover; during the operation of the aforementioned method, to avoid secondary trauma, the burn wound must never be bandaged or disinfected with iodine; only spraying and application are permitted. This application invents a traditional Chinese medicine alcohol dressing and its application method, which is highly targeted, effectively relieves pain and prevents infection, reduces scar formation, and is suitable for different types of burns.
Owner:张建立

Modified exosome as well as preparation method and application thereof

The invention discloses a modified exosome as well as a preparation method and application thereof, and relates to the technical field of biological medicines, CD44 targeted modification and composite active ingredients are synergistic to realize efficient repair of burn wounds and sensitive skin, and the modified exosome can be specifically enriched on the burn wounds or damaged sensitive skin parts through CD44 targeted peptide fragment coupling, so that the effect of repairing the burn wounds and the sensitive skin is achieved. The defects that a traditional repairing product is poor in targeting property and low in active ingredient utilization rate are overcome, the loaded dipotassium glycyrrhizinate, glutathione and FGF form a synergistic effect, wound healing and skin barrier repairing can be promoted through the FGF, the dipotassium glycyrrhizinate and the glutathione can be used for strongly resisting inflammation and oxidation, release of sensitive skin inflammatory factors is reduced, and the repairing effect is achieved. By matching with nitrogen protection incubation and a pulse ultrasonic loading process, the stability of active ingredients is greatly improved, finally, the repair effects that the healing process of burn wounds is remarkably accelerated, and sensitive skin percutaneous moisture loss is obviously reduced are achieved, and safety and effectiveness are both considered.
Owner:JILIN UNIVERSITY

Burn wound abrader

ActiveCN115721384BSurgeryMechanical engineeringEschar
The application discloses a burn wound eschar grinder, which comprises an eschar grinder body, an eschar grinder head arranged in the eschar grinder body, an outer tube arranged on the eschar grinder body, a pus removing assembly arranged on the eschar grinder body, an eschar grinding mechanism arranged in the eschar grinder body and a sundry collecting assembly arranged on the outer tube. The eschar grinder can collect the eschar generated during the pus removing and eschar grinding. The eschar grinder is different from the prior art, and the pus under the eschar can be removed by the pus removing assembly and the eschar grinder head when a medical staff grinds the eschar of a patient. The eschar grinder head is connected with the eschar grinding mechanism by pulling the eschar grinding mechanism upward, and then the eschar grinder head is driven to rotate, so that the ground eschar is prevented from scattering around and further infecting the wound position.
Owner:FIRST HOSPITAL AFFILIATED TO GENERAL HOSPITAL OF PLA

Burn wound negative pressure treatment and drug perfusion combined drainage device

The invention discloses a burn wound negative pressure treatment and medicine perfusion combined drainage device which comprises a shell, a negative pressure mechanism, an infusion mechanism, a drainage opening, a supporting mechanism, a pressing mechanism and an adsorption mechanism, a rotating ring is installed at the top of the shell, and a guide column is arranged on the inner wall of the rotating ring; the supporting mechanism is fixed in the shell and provided with a supporting channel, and the negative pressure mechanism penetrates through the supporting channel. A drainage opening is formed in the surface of the shell; the negative pressure mechanism comprises a connecting port, a negative pressure pipeline and a protruding block, and the connecting port is formed in the top of the negative pressure pipeline. Therefore, negative pressure treatment of the wound surface and medicine perfusion can be carried out synergistically, and wound surface infection can be controlled in time; a negative pressure system does not need to be disassembled and assembled in each time of perfusion, operation is greatly simplified, medical care burden is relieved, frequent operation on a wound surface is reduced, damage to new granulation tissue is avoided, pain of a patient is relieved, and the risk of secondary pollution caused by repeated exposure of the wound surface is reduced.
Owner:TAIHE HOSPITAL OF SHIYAN CITY (AFFILIATED HOSPITAL OF HUBEI UNIVERSITY OF MEDECINE)

Table type negative pressure wound therapeutic apparatus

ActiveCN223453525USuction devicesValvesAcute woundDiaphragm pump
The utility model relates to a table-type negative pressure wound therapeutic apparatus, which comprises a front cover, a back cover and a drainage box which are connected in sequence, and a control panel, a diaphragm pump, a fixed support, a pressure relief valve, a battery pack and a negative pressure tube which are arranged between the front cover and the back cover, and a key panel electrically connected with the control panel is arranged on the outer side of the front cover; through the combined action of the diaphragm pump and the pressure relief valve, the air pressure sensor detects the internal air pressure and feeds back the internal air pressure in real time, the air pressure value is controlled within a specified range, a continuous or intermittent negative pressure mode is met, and the negative pressure type negative pressure negative pressure device is suitable for various treatment modes such as acute wounds, non-acute wounds, diabetic feet, chronic ulcers and burn wounds.
Owner:ZHEJIANG TOP-MEDICAL MEDICAL DRESSING CO LTD

A neural network-based burn identification and effect prediction method and system

PendingCN122336404AEngineeringImage pair
This invention relates to the field of burn wound type identification technology, specifically disclosing a method and system for burn identification and effect prediction based on neural networks, comprising the following steps: S1, acquiring burn wound images and performing preprocessing; S2, constructing a convolutional neural network classification model, employing a transfer learning strategy, and training the convolutional neural network classification model using the preprocessed burn wound images to obtain a trained burn identification model; S3, inputting the burn wound image to be identified into the trained burn identification model, and outputting the burn grade and corresponding thermal damage effect identification results; wherein the burn grades include: first-degree burns, superficial second-degree burns, deep second-degree burns, and third-degree burns; this invention achieves the identification of detailed burn grades and thermal damage effects by constructing and training a convolutional neural network classification model employing a transfer learning strategy.
Owner:NAT UNIV OF DEFENSE TECH

Artificial intelligence-driven burn wound assessment method and system

The invention discloses an artificial intelligence-driven burn wound assessment method and system, and relates to the technical field of medical information processing and intelligent diagnosis, and the method comprises the following steps: S001, employing a fixed imaging attitude to collect continuous short-sequence wound image frames, calculating a brightness change curve of adjacent image frames, generating a light and shade rhythm track, and drawing a beat frequency prompt band, the method is used for marking a light source flicker rule and establishing an initial reference baseline of brightness change. Through brightness breakpoint identification, error shooting parameter calculation, light source phase jitter and inverse rhythm optical shutter regulation and control, active separation and reverse coupling of illumination rhythm and sampling rhythm are realized, periodic flicker interference is effectively eliminated, the brightness stability and texture reduction degree of a wound image are improved, an artificial intelligence evaluation result is more accurate and reliable, and the artificial intelligence evaluation efficiency is improved. And the objectivity and safety of clinical diagnosis are improved.
Owner:AFFILIATED HOSPITAL OF NANTONG UNIV