The invention discloses an external used medicine and process for preparation, which comprises the components as following, raw rheubarb, coptis chinesis, honeysuckle, polygonum ciliinerve, raw gardenburnet, phellodendron bark, radix notoginseng, polygonum cuspidate, astragalus, lithospermum, safflower, myrrh, olibamum, margarita, camphol, zine oxide, and sesame oil, and is processed in steps. The invention sinks gauze dressing in the form of oil solution, and then is stuck on wound, thereby reducing the water evaporation of wound, preventing wound infection, and avoiding wound incrustation,and the effusion of wound can easily mix with the finish oil gauze, which is beneficial for wound drainage, and largely relieves sufferings of burn patients. The invention is an externally used medicine for treating burn wound, which has short course of treatment, fast effect, strong safety, excellent repair virtue for wound, few scars after curing, and no side effect.