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Anti-tuberculosis drug and production method thereof

A technology for tuberculosis and drugs, applied in antibacterial drugs, pharmaceutical formulations, plant raw materials, etc., can solve the problems of few clinical experimental studies, lack of unified syndrome differentiation and diagnosis and treatment standards, and few traditional Chinese medicine preparations, etc., achieve curative effect and non-toxic , Increase the immune function of the body, good curative effect

Inactive Publication Date: 2016-01-27
新疆维吾尔自治区中药民族药研究所
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  • Abstract
  • Description
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Problems solved by technology

[0009] However, the main problem in the current research is the lack of unified syndrome differentiation and diagnosis and treatment standards. The treatment of this disease is mostly limited to general clinical observation, while clinical experimental research is less, and the research on MDR-TB is still in its infancy. stage, especially there are not many traditional Chinese medicine preparations for killing or strongly inhibiting the action of Mycobacterium tuberculosis

Method used

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  • Anti-tuberculosis drug and production method thereof
  • Anti-tuberculosis drug and production method thereof
  • Anti-tuberculosis drug and production method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0161] Example 1: Take the Chinese medicinal materials rhubarb, white peony root, white root, and fenugreek, and grind them into powders below 250 μm, and add 1.5 to 1.7 parts by weight of starch to 1 part of croton kernel powder crushed to 250 μm or less, and mix evenly to obtain croton cream. 3 to 15 parts of Radix Paeoniae Alba, 9 to 15 parts of Baiji, 6 to 15 parts of Rhubarb and Croton Cream: 0.1 to 0.3 parts, 3 to 5 parts by weight of beeswax and 80 to 100 parts by weight of water are added to 100 parts by weight of the total amount, Stir evenly at a temperature of 50-80°C to make pellets of 0.1-0.12g, and then air-dry until the water content is below 10%.

Embodiment 2

[0162] Example 2: Take 3-15 parts of Chinese herbal medicine rhubarb, 9-15 parts of white peony root, 6-15 parts of white peony root, mix and grind them into a powder below 250 μm, take croton kernels and grind them into a powder below 250 μm, add 1.5-1.5 to 1 part of croton kernel powder 1.7 parts by weight of starch and mixed evenly to obtain croton cream, mixed with 0.1 to 0.3 parts of the crushed white peony root, white root and rhubarb mixture with croton cream, and added 3 to 5 parts by weight of beeswax and 80 to 80 parts by weight of 100 parts by weight of the total amount. 100 parts by weight of water, stirred evenly at a temperature of 50-80°C to make 0.08 ～ 0.12g of pellets should be dried until the moisture content is below 8%.

Embodiment 3

[0163] Example 3: Take 3-15 parts of Chinese medicinal materials rhubarb, 9-15 parts of white peony root, 6-15 parts of white peony root, and grind them into 150 μm or less respectively, add 1.5-1.7 weight parts of starch to the croton kernels, and then grind them into 100 μm powder to obtain croton Frost.

[0164] Add 0.1 to 0.3 parts of croton cream to the pulverized Radix Paeoniae Alba, Baiji and Rhubarb, add 3 to 5 parts by weight of beeswax and 80 to 100 parts by weight of water according to the total amount of the above mixture of 100 parts by weight, Stir evenly to make 0.1 ～ 0.2g of pellets should be dried until the water content is below 8%.

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Abstract

The invention discloses an anti-tuberculosis drug and a production method thereof. The anti-tuberculosis drug is mainly prepared from 3-15 parts of rhubarb, 9-15 parts of radix paeoniae alba, 6-15 parts of bletilla striata and 0.1-0.3 part of Semen Crotonis Pulveratum, and is made into pills. The Semen Crotonis Pulveratum is a mixture of croton seed powder and starch. The drug is completely made of Chinese herbal medicines, has the advantages of tuberculosis resistance and sterilization, pus expelling and tissue regeneration promotion, swelling and pain relieving, nerve repairing, promotion of tuberculosis focus absorption and repair, and strengthening of body immune function, etc., is mainly applicable to bone and joint tuberculosis complicated with abscess sinus, spinal tuberculosis complicated with pulmonary tuberculosis, lymphoid tuberculosis, tuberculous pleuritis, intestinal tuberculosis and renal tuberculosis, etc., also has no pain and risk of surgical trauma, and especially has the advantages of small toxic and side effect and adverse reaction, quick effect, short course of treatment and low price, etc.

Description

technical field [0001] The invention relates to an anti-tuberculosis drug and a production method thereof. Background technique [0002] Tuberculosis was once effectively controlled, but since the mid-1980s, the epidemic situation has deteriorated and rebounded sharply. According to WHO estimates, there are 8 million new cases and more than 3 million deaths worldwide every year, forming the third rebound peak. [0003] China ranks second among the 22 countries with a high burden of tuberculosis in the world, with about 550 million people infected with tuberculosis. [0004] Among the many reasons for the resurgence of tuberculosis epidemics, the most important and most harmful are the following two situations: (1) dual infection of HIV / AIDS patients and tuberculosis bacteria, of which tuberculosis has become an important cause of death; (2) multidrug-resistant tuberculosis (MDR- TB) has the potential to make tuberculosis incurable again. [0005] In view of the severe sit...

Claims

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Application Information

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IPC IPC(8): A61K36/898A61P31/06
Inventor 朱国强邱远金贾晓光陈书强李忠民
Owner 新疆维吾尔自治区中药民族药研究所
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