The invention discloses a medicinal composition which is prepared by the following bulk pharmaceutical chemicals of scutellaria baicalensis, honeysuckle, thunder god vine, radix zanthoxyli, bark of ash, polygonum cuspidatum, radix aconiti lateralis preparata, angelica sinensis, white pepper, rheum officinale, gallnut, borneol and liquorice. Conventional auxiliary materials or an excipient can be added in medicinal composition, an extractive and a refining matter to prepare preparation such as injection, a fogging agent, a tablet, a capsule and an oral solution. The medicinal composition has functions of clearing away heat and toxic materials, tonifying spleen and warming the kidney, promoting blood circulation to arrest pain and conducting immune adjustment, is used for therapy or adjuvant therapy of the aids, can obviously improve SD4+ cell quantity and SD4+ / SD8+ ratio of HIV / AIDS patient, and improves or stabilizes immunologic functions of aids patients.