62 results about "Nephrology" patented technology

The invention discloses an integrated nephrology urinary sediment microscopy device which mainly comprises a base body, a high-speed centrifugal device, a liquid taking telescopic device and a microscopy device body. The high-speed centrifugal device is embedded into the base body, the liquid taking telescopic device is connected on the upper portion of the base body through a vertical column and a horizontal supporting plate, the microscopy device body is connected on the upper portion of the horizontal supporting plate through a vertical supporting plate, a first liquid guide protection sleeve and a second liquid guide protection sleeve are longitudinally, bilaterally and parallelly arranged in the inner middle of the liquid taking telescopic device and sleeve a liquid supernatant guide pipe and a urinary sediment guide pipe in a penetrated manner, one end of the liquid supernatant guide pipe is connected with a waste liquid bottle, and the upper end of the urinary sediment guide pipe is communicated with a double-layer slide in the microscopy device body. The device is reasonable in design and convenient to operate, and working efficiency can be greatly improved.

A method for distinguishing between kidney dysfunctions in a mammal, including pre-renal azotemia, an acute renal injury that may progress to acute renal failure, and chronic kidney disease, using a urinary or circulating NGAL assay result that is compared to a predetermined NGAL cutoff level, and a single serum or plasma creatinine measurement. Typically the single creatinine measurement cannot distinguish acute renal injury from chronic kidney disease or pre-renal azotemia, a single measurement of urinary NGAL, combined with the single serum or plasma creatinine measurement, has sufficient sensitivity and specificity to distinguish acute renal injury from normal function, prerenal azotemia, and chronic kidney disease and predicts poor inpatient outcomes. Patients admitted to the emergency department of the hospital with any of acute kidney injury, prerenal azotemia, chronic kidney disease, or even normal kidney function, can be evaluated based on the single measurements of urinary or circulating NGAL, and serum or plasma creatinine. Urinary NGAL level is highly predictive of clinical outcomes, including nephrology consultation, dialysis, and admission to the intensive care unit.

The invention provides a platform convenient for doctor management and patient self-supervision, and aims to assist a patient to know a health condition and remind the patient to timely go back to a hospital for follow-up visit. The platform has main functions of patient archiving, examination index input, follow-up visit plan and rehabilitation plan pushing and reminding, related follow-up visit data analysis and the like, and provides online expert consultation and wardmate communication, thereby facilitating self-management and self-supervision of the patient. While follow-up visit and diagnosis and treatment process management is covered, data accumulated in an operation process is subjected to statistical analysis, so that big data value is comprehensively reflected and powerful data support and decision support are provided for clinic scientific and research of nephrology departments. The follow-up visit is taken as a center; for the patient with the chronic kidney disease, the follow-up visit is performed in the way; the problem that a kidney disease assistant in China at present takes no count of the follow-up visit is solved; the burden of a doctor and the frequency of going to the hospital for the patient are reduced; and a few unnecessary expenses are saved.

A method for distinguishing between kidney dysfunctions in a mammal, including pre-renal azotemia, an acute renal injury that may progress to acute renal failure, and chronic kidney disease, using a urinary or circulating NGAL assay result that is compared to a predetermined NGAL cutoff level, and a single serum or plasma creatinine measurement. Typically the single creatinine measurement cannot distinguish acute renal injury from chronic kidney disease or pre-renal azotemia, a single measurement of urinary NGAL, combined with the single serum or plasma creatinine measurement, has sufficient sensitivity and specificity to distinguish acute renal injury from normal function, prerenal azotemia, and chronic kidney disease and predicts poor inpatient outcomes. Patients admitted to the emergency department of the hospital with any of acute kidney injury, prerenal azotemia, chronic kidney disease, or even normal kidney function, can be evaluated based on the single measurements of urinary or circulating NGAL, and serum or plasma creatinine. Urinary NGAL level is highly predictive of clinical outcomes, including nephrology consultation, dialysis, and admission to the intensive care unit.

The present invention relates to the field of nephrology. More specifically, the present invention provides compositions and methods useful for the study and treatment of acute kidney injury. In one embodiment, the present invention provides a knockout animal whose genome comprises a deletion of exon 2 and exon 3 of kelch-like ECH-associated protein 1 (KEAP1) in T-cells. In another embodiment, a method for treating a subject diagnosed with AKI comprising the steps of (a) isolating T-cells from the subject; (b) activating Nrf2 expression in the isolated T-cells; and (c) administering the T-cells back to the subject.

The present invention relates to the field of nephrology. More specifically, the present invention provides methods and compositions useful for more precisely estimating glomerular filtration rate (GFR). In a specific embodiment, a method for calculating the estimated glomerular filtration rate (eGFR) in a patient comprises the steps of (a) measuring the level of one or more metabolites using mass spectrometry from a blood sample obtained from the patient; and (b) calculating the eGFR using an algorithm that utilizes the measured levels of the one or more metabolites.

A pharmaceutical composition having thrombolytic, anti-inflammatory and cytoprotective properties is described. The composition contains active proteases attached to a gel or to a mixture of a gel with a water-soluble polymer, said attachment being achieved with the help of radiation, preferably with the help of gamma-radiation or a flow of accelerated electrons. As the proteases the composition contains proteases which are stable at a temperature of up to 70° C., preferably at 30-40° C., for instance such as subtilysine, trypsin, chemotrypsin, papain or streptokinase. The gel is preferably polyethylene glycol gel, dextran gel, or polyglycane gel, and the water-soluble polymer is polyethylene glycol, polyvinyl alcohol, dextran or polyglycane. The method of preparing said composition and its use are also disclosed. The composition has a broad range of application, and can be used in cardiology, nephrology, surgery, rheumatology, gynecology and gastroenterology.

The invention relates to a peritoneum dialysis locator for nephrology. The locator comprises a dialysis outer tube, an outer suction cup is arranged in the middle of the dialysis outer tube, a sealingring is hingedly mounted on the inner side of the upper portion of the outer suction cup, the inner side of the sealing ring is in contact with the dialysis outer tube, the bottom surface of the outer suction cup is hingedly provided with a circle of positioning ring, a large sealing ring is fixedly mounted on the outer side of the bottom surface of the positioning ring, two uniformly distributedannular grooves are respectively formed in the bottom surface of the middle of the positioning ring, the annular grooves are respectively provided with cooperating air bags, the bottom surfaces of the air bags are fixedly provided with circles of sealing strips, a first adhesive layer is fixedly mounted on the inner side of the bottom surface of the positioning ring, an inclined piston tube is fixedly mounted on the left side of the outer suction cup, a through groove is formed in the life side of the middle of the piston tube, a moving block is arranged in the through hole, and the moving block can move along the through groove. The locator has reasonable structural design, simple installation, time and labor saving and firm fixing, an inner suction cup and the outer suction cup are double-fixed, the fixing effect is good, double sealing improves air tightness of fixing, and the air leakage or the poor fixing effect is avoided.

A pharmaceutical composition having thrombolytic, anti-inflammatory and cytoprotective properties is described. The composition contains active proteases attached to a gel or to a mixture of a gel with a water-soluble polymer, said attachment being achieved with the help of radiation, preferably with the help of gamma-radiation or a flow of accelerated electrons. As the proteases the composition contains proteases which are stable at a temperature of up to 70 DEG C, preferably at 30-40 DEG C, for instance such as subtilysine, trypsin, chemotrypsin, papain or streptokinase. The gel is preferably polyethylene glycol gel, dextran gel, or polyglycane gel, and the water-soluble polymer is polyethylene glycol, polyvinyl alcohol, dextran or polyglycane. The method of preparing said composition and its use are also disclosed. <??>Advantages: the claimed composition is noted for a broad range of application and can be used in cardiology, nephrology, surgery, rheumatology, gynecology and gastroenterology.

The invention belongs to the field of nephrology, and relates to a chronic kidney disease angiosteosis experiment model and a making method thereof. The chronic kidney disease angiosteosis experiment model is established by using C57BL / 6 mouse molding through cooperation of combination of adenine and vitamin D with a high-phosphorus and low-protein diet intervention mode. The making method has the advantages of short modeling time and good stability; and the established chronic kidney disease angiosteosis experiment model can be further used to screen drugs for treating chronic kidney disease angiosteosis and research mechanisms of the drugs.

The invention discloses a nephrology nursing device with a massage function, which comprises an airbag, a controller is fixedly installed on the left side of the bottom of the airbag, an inflatable tube is fixedly installed on the top of the airbag, and a controller is fixedly installed on the inflatable tube. A motor box is fixedly installed on the front surface of the airbag, and the top of the inner cavity of the motor box is fixedly installed with a dust removal box, a cooling box and a battery in sequence from left to right, and both sides of the inner cavity of the motor box are fixedly installed There are slide rails, slide bars matching with the slide slots are arranged in the slide slots of the slide rails, and massage blocks are fixedly installed at opposite ends of the two slide bars. The nephrology nursing device with massage function achieves the effect of driving the massage block to move through the improvement of the motor box, thereby facilitating the massage of the patient, relieving the pain of the patient and speeding up the recovery of the patient, improving the device. The efficiency of use is convenient for users and the efficiency of nursing care is improved.

The invention discloses a system and a method for automatically generating a nutrition treatment scheme of a renal failure patient. The method comprises the following steps: acquiring first user information; according to the first user information, obtaining first medical record information, the first medical record information comprises a first test result, and the first test result is nephrology examination test data; obtaining a first patient grade according to the first test result; according to the first medical record information, obtaining a first food taboo disease which is not a kidney disease; inputting the first patient level and the firstfood taboo disease into a scheme generation model to obtain a first treatment scheme; obtaining a first dietary habit according to the first user information; and obtaining a first nutrition treatment scheme according to the first treatment scheme and the first dietary habit. The technical problems that in the prior art, a nutrition treatment scheme for a patient with chronic renal failure is single, only afood taboo requirement is given, but guidance of a specific recipe is lacked, the patient executes the scheme blindly, nutrition imbalance of the patient is possibly caused, and recovery is not facilitated are solved.

The invention provides a woven reinforced degradable polyurethane elastomer artificial blood vessel and a preparation method thereof. The inner layer of the artificial blood vessel adopts activated H2N-PEG-COOH, heparin and (Mpa)-GGGGGREDV polypeptide to treat a C-PEEUU-NH2 electrospun nanofiber tubular stent to obtain a C-PEEUU-PEG-Hep / REDV tubular stent, the middle layer adopts a woven reinforced layer of nanofiber yarns woven by dissolving and mixing one or more master batches of PLGA, PDO and PGA according to a mass ratio, and the outer layer is a macroporous layer prepared by thermally induced phase separation. The woven reinforced degradable polyurethane elastomer artificial blood vessel provided by the invention can be used for tissue regeneration and construction of cardiovascularand cerebrovascular diseases, the preparation method is simple and efficient, the price is low, and the prepared artificial blood vessel has resilience, compliance, bursting strength and biocompatibility matched with autologous vascular tissues. The artificial blood vessel has no hypersensitivity to a human body in a transplantation operation, has affinity with blood and peripheral tissues in thehuman body, and has a good application prospect in repair operations of cardiology surgery, nephrology surgery and brain surgery.

The invention provides a positioner for peritoneal dialysis in the Department of Nephrology, which relates to the technical field of medical devices and includes a positioning tube, a catheter and a belt. An implant is inserted and fixedly connected, and a side wall of the implant is provided with a ventilation device, and the ventilation device includes an airway inserted and fixedly connected to one side of the implant, and one side of the airway The wall is fixedly connected with a ventilating head, the implant is provided with a sealing device, the catheter is inserted into the implant and against its inner wall, one side wall of the adsorption block is fixedly connected with two symmetrically arranged installation blocks, and the installation block is set There are fixtures. The sealing device is used to effectively seal the implant, and when not in use, it can seal the implant to prevent foreign matter from entering the body and affecting the health of the user. The application of this device effectively improves the safety of the device.

The present invention relates to the technical field of medical devices, in particular to a dialysis tube positioning device for nephrology, which includes a plurality of clip-connected fixing frames, wherein the fixing frames are composed of a main clip, a left clip, a right clip, and a clip. , tie-down belt, clamping assembly and winding assembly, the main clamping plate has two and forms a circular structure with the left clamping plate and the right clamping plate, and the binding belt runs through the main clamping plate and slides with the main clamping plate connected, the clamping block is clamped on one of the main clamping boards, the clamping block is provided with a clamping slot for clamping the dialysis tube, the two adjacent fixing frames are clamped and connected by clamping components, and the binding The belt runs through the clamping assembly and is fixedly connected with the clamping assembly. The two ends of the binding belt are clamped and connected in the winding assembly to form a structure for adjusting the size of the circular structure surrounded by the fixing frame. The invention realizes the dialysis tube It is firmly fixed on the arm, avoiding the movement of the dialysis tube from affecting the dialysis treatment, and has broad application prospects in the technical field of medical devices.

The invention discloses a medicine for treating sepsis in nephrology, which is prepared from the following raw materials in parts by weight: 2-8 parts of rhubarb, 3-10 parts of scutellaria baicalensis, 4-10 parts of salvia miltiorrhiza, and 3-9 parts of red peony , 7‑15 parts of Panax notoginseng, 4‑15 parts of Citrus aurantium, 3‑10 parts of Pulsatilla chinensis, and 5‑15 parts of Patrinia. The medicine for treating sepsis prepared by the nephrology department of the invention can effectively improve the treatment effect and has no toxic or side effects and adverse reactions. The preparation adopts the step-by-step method of preparing extracted powder and mixing, and the preparation method is simple and novel.

The invention provides a kidney puncture device for nephrology which prevents the needle handle from slipping off during use. A vertical plate inserted into the fastening plate is fixed, airbag one is fixedly installed on the side of the backing plate close to the twist ring, a wedge-shaped block is fixedly connected to the inner wall of the twist ring, and airbag two is fixedly installed under the fastening plate, and the second airbag passes through The hollow ring and the ventilation tube are connected with the first air bag. When the twisted ring is rotated, the wedge-shaped block squeezes the fastening plate and the second air bag at the same time. The fastening plate is protruded inward and is pressed against the outer wall of the puncture needle handle to enhance the stability of the puncture needle handle. The gas in the second airbag is squeezed into the first airbag, and the volume of the first airbag becomes larger. Continue to push the fastening plate to further strengthen the clamping firmness. By setting the hollow ring, different airbags can be adjusted to ensure All fastening plates rest on the needle shaft.

The invention discloses a medical nephrology dialysis device which comprises a machine frame and a dialysis device. The top of the machine frame is provided with a blood outlet tube, and the blood outlet tube passes into the machine frame, the top of the machine frame is provided with a blood inlet tube, the blood inlet tube passes into the machine frame, the upper right corner of the machine frame is provided with a push rod, and the push rod is closely connected with the machine frame. The medical nephrology dialysis device is reasonable in design, a roller is mounted at the bottom of the machine frame, and a roller fixator is mounted outside the roller. The device can be pushed to move through the roller. After the device stops moving, the roller is fixed through a roller fixing device,the fixation and movement of the device are facilitated, medical workers' workload is reduced, and the problem that it is inconvenient to move the device is solved.

The invention discloses a peritoneal dialysis apparatus for nephrology use, and relates to the technical field of medical instruments. The peritoneal dialysis apparatus for nephrology use comprises a liquid intake bag, a drip cup, a heating detection clamp, a three-way liquid exchange valve, a liquid exchange tube, a drainage measuring bottle and a drainage bag; the drip cup is clamped with the heating detection clamp, and communicates with the three-way liquid exchange valve and the liquid exchange tube arranged below; the three-way liquid exchange valve and the liquid exchange tube comprise a liquid intake channel and a liquid outlet channel; and the end of the liquid outlet channel is connected with the drainage measuring bottle and the drainage bag. Inlet and outlet amounts of dialysate can be accurately observed through the liquid intake bag as well as the drainage measuring bottle and the drainage bag arranged below; the drip cup is clamped with the heating detection clamp; dropping speed (flow rate) of the dialysate can be controlled by a dropping speed detection device; and the temperature of the entering dialysate can be adjusted by a constant-temperature heating device. Thus, the peritoneal dialysis apparatus for nephrology use is rational in structural design, convenient and practical to use, and suitable for promoted use by medical institutions.

The present invention relates to the field of nephrology. More specifically, the present invention provides compositions and methods useful for the study and treatment of acute kidney injury. In one embodiment, the present invention provides a knockout animal whose genome comprises a deletion of exon 2 and exon 3 of kelch-like ECH-associated protein 1 (KEAP1) in T-cells. In another embodiment, a method for treating a subject diagnosed with AKI comprising the steps of (a) isolating T-cells from the subject; (b) activating Nrf2 expression in the isolated T-cells; and (c) administering the T-cells back to the subject.

The invention discloses an integrated nephrology urinary sediment microscopy device which mainly comprises a base body, a high-speed centrifugal device, a liquid taking telescopic device and a microscopy device body. The high-speed centrifugal device is embedded into the base body, the liquid taking telescopic device is connected on the upper portion of the base body through a vertical column and a horizontal supporting plate, the microscopy device body is connected on the upper portion of the horizontal supporting plate through a vertical supporting plate, a first liquid guide protection sleeve and a second liquid guide protection sleeve are longitudinally, bilaterally and parallelly arranged in the inner middle of the liquid taking telescopic device and sleeve a liquid supernatant guide pipe and a urinary sediment guide pipe in a penetrated manner, one end of the liquid supernatant guide pipe is connected with a waste liquid bottle, and the upper end of the urinary sediment guide pipe is communicated with a double-layer slide in the microscopy device body. The device is reasonable in design and convenient to operate, and working efficiency can be greatly improved.

The invention discloses a kidney warming chair for nephrology. The kidney chair has ingenious structure, powerful functions, and simple operation. By using this device, the patient's kidney can be treated with hot compresses, so as to dilate the local capillaries of the patient's kidney, promote the blood circulation of the patient's kidney, and effectively dispel cold and dampness. It can reduce the pain of patients after renal surgery and ensure the progress of renal rehabilitation.

The invention discloses a peritoneal dialysis device for nephrology. The device comprises a circular base, a collecting groove is formed in the left end of the upper surface of the circular base, theinner side surface of the collecting groove is provided with a second dialysis bag, the middle of the upper surface of the circular base is provided with a telescopic rod, the telescopic rod is in screwed connection with a positioning bolt through a threaded hole formed in the middle of the outer side surface, hooks are arranged on the upper end of the outer side surface of the telescopic rod, thenumber of the hooks is four, and the four hooks are evenly distributed on the outside surface of the telescopic rod; the peritoneal dialysis device has a compact structure, convenient operation and small occupied space for use, and can effectively prevent a dialysis hole on a dialysis tube from being blocked and wrapped by intra-abdominal structures such as omentum majus and the like, a locking universal wheel is in combination with a push rod so that the device can conveniently move, the setting of the hooks facilitates the hanging of a first dialysis bag, and the setting of the telescopic rod enables the first dialysis bag to be conveniently adjusted for lifting and lowering.

The invention discloses a puncture needle fixation apparatus for renal internal medicine. The puncture needle fixation apparatus comprises a poisoning seat used for positioning the puncture position of a patient and limit pieces used for adjusting depth of a puncture needle, a tubular lug boss is arranged on the upper end face of the positioning seat, a concave portion is formed in the center of the tubular lug boss, a needle hole penetrating the lower end face of the positioning seat is arranged in the bottom center of the concave portion, concave limit grooves matched with the limit pieces to limit the rotation angle of the limit pieces are arranged on two upper sides of the tubular lug boss, the limit pieces include a first limit piece and a second limit piece which are detachably connected, a first arc portion of a semicircular structure is arranged in the middle of the first limit piece, the limit pieces are fixed on the puncture needed through fixation of the first limit piece and the second limit piece with each other, constraint of puncture depth of the puncture needle is achieved by allowing lower end faces of the limit pieces to be abutted against bottoms of the limit grooves when the puncture needle penetrates the needle hole of the positioning seat. The puncture needle fixation apparatus is reliable in scheme implementation and capable of reducing operation difficulty and intensity of medical workers.

The invention relates to a urinary catheter system for nephrology, comprising: a catheter body, a suction tube and a flexible suction container; the catheter body includes an insertion section, an external section and a urination section, and the insertion section passes through the external The set section is connected with the urination section, the external section communicates with the first end of the suction pipe, the second end of the suction pipe is detachably connected with the flexible suction container, and the flexible suction container It communicates with the second end of the suction pipe. By connecting a flushing tube to the external section of the catheter body, the flexible flushing container can extract urine from the external section, making the flexible flushing container closer to the insertion section, so that the blood clot solidified in the insertion section can be removed. Being flushed away, the dredging effect on the catheter body is better and the efficiency is higher, and since the flexible flushing container is close to the insertion section, it can be performed with a small suction force to reduce the patient's discomfort.

The invention discloses a dry powder bag and dialysis auxiliary equipment for nephrology. The dry powder bag includes a bag body; The material guide tube connected to the flaring head, the deformation section formed on the material guide tube and the cut-off ring arranged on the deformation section; the preparation device includes a cabinet; a liquid preparation device; the liquid preparation device includes a The accommodating chamber, the preparation chamber located in the accommodating chamber and the swinging part matched with the preparation chamber; the preparation chamber is provided with a stirring device, and the rotation direction of the stirring device is opposite to that of the preparation chamber. In the present invention, the dry powder bag can be placed in the powder chamber to realize the conduction with the discharge pipe, and the operation is simple; there is no need to frequently replenish the powder chamber, and the work efficiency is high; a stirring device is set in the preparation chamber, which enhances the preparation The turbulence effect of the indoor liquid, the high dissolution rate of the dry powder, and the precise control of the concentration of the dialysate.

The invention discloses a nephrology auxiliary therapeutic instrument, which relates to the technical field of medical equipment. The nephrology auxiliary therapeutic instrument comprises a movable chair, a supporting frame and electromagnetic wave searchlights. The movable chair has a chair back which comprises a supporting layer and a therapeutic layer in sequence from front to back. The supporting layer and the therapeutic layer are laminated and fixedly connected on vertical columns of the chair back, supporting frames are fixed on the supporting layer, and the electromagnetic wave searchlights are fixed on the therapeutic layer. Each supporting frame comprises connecting rods, a supporting rod and limiting blocks, one end of each connecting rod is hinged and connected with one vertical column of the chair back, the other end of each connecting rod is hinged and connected with the supporting rod, and the connecting rods and the supporting rod form a double-crank mechanism. Two pairs of the double-crank mechanisms are formed, and are mounted on the two vertical columns of the chair back separately. The limiting blocks are positioned under hinged parts of the connecting rods and the vertical columns, and are fixedly connected to the inner sides of the vertical columns. The nephrology auxiliary therapeutic instrument can ensure that a patient is safe and cannot be burnt when the nephrology auxiliary therapeutic instrument is in use, and the patient can reach a comfortable and relaxed state without causing muscle and bone fatigue.

The invention discloses a urine sampler for nephrology urine test, relates to the technical field of nephrology urine test sampling, comprising a sampling cup, a sampling tube horizontally arranged on one side of the sampling cup, and a circular tube screwed to the liquid inlet end of the sampling tube A cylinder connector, the air in the sampling tube is drawn out, and the cylinder connector is blocked at the liquid inlet end of the sampling tube, so that the inside of the sampling tube is in a state of negative pressure and vacuum. The beneficial effects of the present invention are: when the urine sample in the sampling cup is introduced into the sampling tube, there is no need to tilt the sampling cup, and only the sampling tube and the cylindrical connecting piece on it need to be rotated until the connecting tube in the piercing piece of the sealing cap is pierced. When the sealing cap in the cylindrical connecting piece is worn, and the liquid outlet hole on the connecting pipe is located in the sampling pipe, the urine sample in the sampling cup will be automatically sucked into the sampling pipe.