The invention relates to a device for capturing at least one pair of cells in a solution containing at least one first
cell (C1) of a first type and at least one second
cell (C2) of a second type, said device comprising:-a
microfluidic channel (3) adapted for a unidirectional flow (F) of the solution; -a first trap (1) comprising a pair of first fingers (10a, 10b) arranged in the
microfluidic channel (3), at least one of the first fingers (10a, 10b) being coupled with a respective first
actuator (11a, 11b) configured to adjust the first trap (1) in a direction transverse to the flow (F) between an open position allowing the first cells to flow between the first fingers (10a, 10b) and a closed position allowing the first cells to flow between the first fingers (10a, 10b); a closed position adapted to the size of the first
cell to allow capture of the first cell between the first fingers (10a, 10b); 15-a second trap (2) comprising a pair of second fingers (20a, 20b) arranged in the
microfluidic channel (3), at least one of the second fingers (20a, 20b) being coupled with a respective second
actuator (21a, 21b) configured to adjust the second trap (2) in a direction transverse to the flow (F) between an open position allowing second cells to flow between the second fingers (20a, 20b) and a closed position allowing second cells to flow between the second fingers (20a, 20b). A closed position adapted to the size of the second cell to allow capture of the second cell between the second fingers (20a, 20b); wherein the first trap (1) is arranged relative to the second trap (2), when the first trap and the second trap are in a closed position, so as to form a
cell pair comprising captured first and second cells, such that the second cells physically or chemically interact with the first cells.