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Medicine composition for preventing and treating AIDS and its prepn process and use

A composition and AIDS technology, applied in the field of medicine, can solve problems such as difficulty in applying to large sample groups of patients, unfavorable enrichment of medicinal substances, and difficulty in controlling the quality of medicinal raw materials

Inactive Publication Date: 2007-08-22
广州中医药大学热带医学研究所
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The purpose of the present invention is also to try to solve the ubiquitous problems in the Chinese herbal medicine combinations for the treatment of AIDS at the present stage that the quality of the raw materials of the medicinal materials is difficult to control, the backward preparation process is not conducive to enriching the effective substances and exerting their efficacy, the curative effect is difficult to evaluate and obtain recognition, and there is a lack of standardization. Problems in preparation quality standards, difficulty in applying to patients with large sample groups, etc.

Method used

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  • Medicine composition for preventing and treating AIDS and its prepn process and use
  • Medicine composition for preventing and treating AIDS and its prepn process and use

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0107] Example 1 Preparation method of the pharmaceutical composition tablet of the present invention

[0108] The mass percentage of the composition: Polygonum cuspidatum 30%, Epimedium 20%, Wintergreen 20%, Ligustrum lucidum 20%, Licorice 10%.

[0109] Take Polygonum cuspidatum and Mao Dongqing, add 8 times the volume fraction of 70% ethanol and reflux for 3 times, 2h each time, filter, combine the ethanol solution, and recover the ethanol under reduced pressure. The thick paste is made into a 30% ethanol solution of 5 times the amount of medicinal materials. , Respectively on the treated D-101 macroporous resin column, first eluted with purified water (about 2 column volumes), and then eluted with volume fraction of 60% ethanol (about 6-8 column volumes), collect 60 % Ethanol eluent, recover ethanol under reduced pressure, and thick paste for later use; take Ligustrum lucidum and licorice, add 8 times the volume fraction of 70% ethanol to reflux and extract 3 times, 2h each tim...

Embodiment 2

[0110] Example 2 Preparation method of the pharmaceutical composition tablet of the present invention

[0111] Percentage of composition: Polygonum cuspidatum 20%, Mao Dongqing 20%, Epimedium 15%, Ligustrum lucidum 10%, Licorice 5%, Astragalus 5%, Arctium burdock 5%, Drynaria 5%, Salt tree 5% , Scutellaria 5%, Curcuma 2.5%, Lithospermum 2.5%.

[0112]Take Polygonum cuspidatum and Mao Dongqing, add 8 times the volume fraction of 70% ethanol to reflux and extract 3 times, 2h each time, filter, combine the ethanol solution, recover the ethanol, and make the thick plaster into a 30% ethanol solution of 5 times the amount of medicinal materials, respectively On the D-101 macroporous resin column that has been processed, first eluted with purified water (about 2 column volumes), and then eluted with volume fraction 60% ethanol (about 6-8 column volumes), and collected 60% ethanol The eluent, the ethanol is recovered under reduced pressure, and the thick paste is ready for use; take Ligu...

Embodiment 3

[0113] Example 3 Preparation method of the pharmaceutical composition capsule of the present invention

[0114] Composition percentage: Polygonum cuspidatum 25%, Mao Dongqing 20%, Epimedium 20%, Ligustrum lucidum 10%, Licorice 5%, Astragalus 5%, Arctium burdock 5%, Drynaria 5%, Curcuma 2.5%, Purple Grass 2.5%.

[0115] Take Polygonum cuspidatum and Mao Dongqing, add 8 times the volume fraction of 70% ethanol and reflux for 3 times, 2h each time, filter, combine the ethanol solution, and recover the ethanol under reduced pressure. The thick paste is made into a 30% ethanol solution of 5 times the amount of medicinal materials. , Respectively on the treated D-101 macroporous resin column, first eluted with purified water (about 2 column volumes), and then eluted with volume fraction of 60% ethanol (about 6-8 column volumes), collect 60 % Ethanol eluate, recover ethanol under reduced pressure, and thick paste for later use; take Ligustrum lucidum, licorice, burdock seed, add 8 times ...

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Abstract

The present invention discloses one kind of medicine composition for preventing and treating AIDS and its preparation process and use. The medicine composition consists of active ingredient and auxiliary ingredient, and may be prepared into granule, tablet, capsule, oral liquid or injection. It has the functions of inhibiting the copying of HIV, promoting immunologic reconstruction of the AIDS patient, delaying disease and clinical complication, and synergizing and attenuating in high efficiency retrovirus resisting therapy. The present invention has wide application foreground.

Description

Technical field [0001] The present invention relates to a medicine. Specifically, it relates to a pharmaceutical composition with the effect of preventing and treating AIDS, and its preparation method and application. Background technique [0002] AIDS is one of the major infectious diseases caused by human immunodeficiency virus (HIV) infection that seriously endangers human health and has a serious social impact. It is a malignant infectious disease that is still incurable. So far, there are more than 70 million people living with HIV worldwide, and more than 30 million people have died of AIDS. There are more than 800,000 HIV-infected people in my country, and the epidemic has entered a stage of rapid transmission, and the spreading situation is very severe. If it is not effectively controlled, it will have a serious impact on my country's social stability and economic development. [0003] High-efficiency antiretroviral therapy (HAART, a combination of reverse transcriptase i...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61K9/08A61K9/10A61K9/14A61K9/16A61K9/20A61K9/48A61P31/18A61K35/56A61K35/586
Inventor 符林春胡英杰
Owner 广州中医药大学热带医学研究所
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